Clinical trials: Ocd
OCD, Major Depressive Disorder (MDD)
Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics
This is an observational study which does NOT directly administer a psychedelic substance but rather recruits participants who are already participating in another clinical trial in which they may receive a serotonergic…
- Conditions
- OCD, Major Depressive Disorder (MDD), Alcohol Use Disorder (AUD), Healthy Volunteer
- Trial name
- NCT06624137
- Testing
- Serotonergic Psychedelic
- Where
- 2 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Yale University
Obsessive-compulsive Disorder
Ketamine Infusion for Obsessive-Compulsive Disorder
Roughly one-third of patients with obsessive-compulsive disorder (OCD) do not experience significant clinical benefit from first-line interventions such as pharmacotherapy with selective serotonin reuptake inhibitors (SSRI) or…
- Trial name
- NCT01349231
- Testing
- ketamine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Yale University
Obsessive-Compulsive Disorder
Novel Deep Brain Stimulation in Ventral Capsule and Stratum for Refractory Obsessive-Compulsive Disorder
Refractory obsessive-compulsive disorder (OCD) is a disabling condition. Deep brain stimulation (DBS) of ventral capsule/ventral striatum(VC/VS) is potentially the most effective treatment for refractory OCD.
- Trial name
- NCT02590445
- Testing
- deep brain stimulation system
- Where
- China
- Volunteers
- 8 people
- Sponsor
- Ruijin Hospital
Obsessive Compulsive Disorder
Transcranial Magnetic Stimulation (TMS) in Obsessive Compulsive Disorder (OCD): Mechanisms and Biomarkers
The purpose of this study is to test the efficacy of 1-Hz repetitive transcranial magnetic stimulation (TMS) over the pre-supplementary motor area as a treatment for obsessive compulsive disorder.
- Trial name
- TMSOCD (NCT02355002)
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Massachusetts General Hospital
Claustrophobia, Obsessive-Compulsive Disorder
Efficacy of Targeted Memory Reactivation for Enhancing Exposure Therapy
This study evaluates whether a scent applied during exposure therapy and during subsequent sleep will increase the durability of treatment effects for individuals with fear of spiders, contamination, and enclosed spaces.
- Conditions
- Claustrophobia, Obsessive-Compulsive Disorder, Arachnophobia
- Trial name
- NCT04663672
- Testing
- Experimental Scent, Control Scent, No-Scent Control
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- University of Texas at Austin
Obsessive-Compulsive Disorder
A Study to Evaluate the Efficacy and Safety of Adjunctive Troriluzole in Obsessive-Compulsive Disorder
The purpose of this study was to evaluate the efficacy and safety of troriluzole as adjunctive therapy compared to placebo in participants with Obsessive Compulsive Disorder (OCD).
- Trial name
- NCT04693351
- Testing
- Troriluzole
- Where
- 89 sites in United States, Canada and 5 more
- Volunteers
- 589 people
- Sponsor
- Biohaven Pharmaceuticals, Inc.
Autism Spectrum Disorders, Autism
Psychotherapy for Anxiety in Children With Autism Spectrum Disorder
Anxiety disorders affect 40 to 50% of children with autism spectrum disorders (ASD), contributing to substantial distress and impairment.
- Conditions
- Autism Spectrum Disorders, Autism, Asperger's Syndrome, Pervasive Developmental Disability - Not Otherwise Specified
- Trial name
- TAASD (NCT02028247)
- Testing
- Personalized Cognitive-behavioral therapy, Standard Practice Cognitive-behavioral therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Obsessive-Compulsive Disorder
Electrical Stimulation of the Internal Capsule for Intractable Obsessive-compulsive Disorder (OCD)
This study will evaluate the safety and effectiveness of deep brain stimulation in treating people with severe and otherwise treatment-resistant obsessive-compulsive disorder.
- Trial name
- NCT01061983
- Testing
- Medtronic Activa Deep Brain Stimulation
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Butler Hospital
Osteochondritis Dissecans Knee, Psychological Stress
Psychological Response and Readiness Associated With OCD of the Knee
This study primarily aims to determine whether patients diagnosed with osteochondritis dissecans (OCD) of the knee experience psychological stress due to their diagnosis and treatment plan.
- Trial name
- NCT04649905
- Testing
- Surgical Treatment, Nonoperative Treatment
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- Boston Children's Hospital
Obsessive-Compulsive Disorder
Randomized Controlled Trial of Intranasal Ketamine vs. Intranasal Midazolam in Individuals With OCD
Obsessive-compulsive disorder (OCD) is a common illness that causes significant distress and impairment. Currently, serotonin reuptake inhibitors (SRIs) are the only medications that are FDA-approved to treat OCD.
- Trial name
- NCT02206776
- Testing
- Intranasal Ketamine, Intranasal Midazolam
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- New York State Psychiatric Institute
OCD
Individual Versus Group Exposure With Response Prevention (ERP) for the Treatment of Obsessive Compulsive Disorder (OCD)
The primary objective is to examine the efficacy of implementing evidence based Exposure and Response Prevention (ERP) within group therapy versus individual therapy by monitoring reduction of Obsessive-Compulsive Disorder (OCD)…
- Trial name
- NCT03926546
- Testing
- ERP for Individuals
- Where
- United States
- Sponsor
- Baylor College of Medicine
Obsessive-Compulsive Disorder
Precision Brain Mapping to Predict and Track Response to Exposure and Response Prevention Therapy in Youth With Obsessive-Compulsive Disorder
The goal of this clinical trial is to learn whether brain scan results can help predict and track changes in obsessive-compulsive disorder, or OCD, symptoms in children and teens ages 10 to 17 who receive Exposure and Response…
- Trial name
- NCT07570108
- Testing
- Exposure and Response Prevention Therapy, Clinical Assessments, Research MRI Sessions
- Where
- United States
- Sponsor
- Weill Medical College of Cornell University
Trichotillomania
Technology Assisted Treatment of Trichotillomania: Open Trial
This open-label feasibility trial evaluates the use of the Keen2 awareness bracelet for adults with trichotillomania (hair-pulling disorder). Participants will use the bracelet for eight weeks.
- Trial name
- NCT07224126
- Testing
- Keen2 Predictive Awareness Bracelet
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- HabitAware Inc.
Obsessive-Compulsive Disorder
Deep-brain Stimulation in Obsessive-compulsive Disorder: Randomized, Double-blinded Clinical Trial
A prospective, randomized, double-blinded study was conducted in 7 OCD patients during which 4 electrode contacts along a striatal axis were stimulated bilaterally.
- Trial name
- 10/131 (NCT03217123)
- Testing
- Deep Brain stimulation
- Volunteers
- 7 people
- Sponsor
- Hospital San Carlos, Madrid
Obsessive Compulsive Disorder
Augmentation in Tx-resistant OCD: an Open Label Trial
This study examines the use of Acamprosate (Campral(R)) in the treatment of Obsessive Compulsive Disorder (OCD). The treatment of this condition is difficulty and a large percentage of patients fail to respond to medications and…
- Trial name
- NCT00590642
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Creighton University
Obsessive-Compulsive Disorder
The Cost of Obsessive-compulsive Disorder (OCD) in China
The purpose of this study is to estimate the cost of obsessive-compulsive disorder in China based on the prevalence rate from a social perspective.
- Trial name
- OCD (NCT04215549)
- Testing
- No intervention
- Where
- China
- Sponsor
- Shanghai Mental Health Center
Obsessive-compulsive Disorder
Stepped Care for Treating Obsessive-Compulsive Disorder
This study will determine the effectiveness and cost-effectiveness of a stepped-care treatment program for people with obsessive-compulsive disorder.
- Trial name
- NCT00316355
- Testing
- Traditional CBT, Stepped-Care CBT
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Hartford Hospital
Obsessive-Compulsive Disorder
Extending Ketamine's Effects in OCD With Exposure and Response Prevention (EX/RP)
This study investigates if a single dose of IV Ketamine can rapidly improve Obsessive-Compulsive Disorder (OCD) symptoms and whether these effect can be maintained with a condensed course of a type of Cognitive Behavioral Therapy…
- Trial name
- NCT02062658
- Testing
- Ketamine, Exposure and Response Prevention
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- New York State Psychiatric Institute
Obsessive-Compulsive Disorder
Cognitive Bias Modification for Thought-Action Fusion
An important cognitive bias in many emotional disorders, particularly obsessive-compulsive disorder (OCD), is thought-action fusion (TAF).
- Trial name
- TAF (NCT03921255)
- Testing
- Cognitive Bias Modification
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Milwaukee
Obsessive-Compulsive Disorder (OCD), Schizophrenia and Schizophrenia Spectrum Psychosis
Obsessive-Compulsive Disorder: Insight, Trauma, and Links to Schizophrenia Spectrum Disorders
This study aims to better understand Obsessive-Compulsive Disorder (OCD) by examining the types and patterns of OCD symptom presentation. The investigators seek to determine how these symptoms impact overall daily functioning.
- Trial name
- NCT07092826
- Testing
- Psychopathological assessment and non-invasive multisensory stimulation
- Where
- 2 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Matteo Tonna