Clinical trials: Ocd
Obsessive-Compulsive Disorder
Using Online Delivered Therapy and Brain Imaging to Better Understand OCD
This study will implement an e-CBT program for OCD and observe its effects on brain activation levels using functional magnetic resonance imaging (fMRI).
- Trial name
- NCT04630197
- Testing
- e-CBT
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Callum Stephenson
Obsessive-Compulsive Disorder, Transcranial Magnetic Stimulation
Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment for Obsessive Compulsive Disease
To investigate the treatment effect of repetitive transcranial magnetic stimulation on Obsessive-compulsive disorder, and the underlying neural mechanism by functional MRI.
- Conditions
- Obsessive-Compulsive Disorder, Transcranial Magnetic Stimulation, Functional Magnetic Resonance Imaging, Event-Related Potentials
- Trial name
- NCT03393078
- Testing
- transcranial magnetic stimulation with real coil
- Where
- China
- Volunteers
- 37 people
- Sponsor
- Anhui Medical University
Obsessive Compulsive Disorder
Genetics of Obsessive-Compulsive Disorder
The purpose of this study is to identify genes that affect susceptibility to obsessive-compulsive disorder (OCD). By identifying genes that increase or decrease the risk of OCD, researchers can better understand how the condition…
- Trial name
- NCT00001548
- Where
- United States
- Volunteers
- 1,067 people
- Sponsor
- National Institute of Mental Health (NIMH)
Obsessive-Compulsive Disorder
Reinforcement Learning and Obsessive-compulsive Disorder: Exploring the Role of the Orbitofrontal Cortex
Obsessive-compulsive disorder (OCD) is a neuropsychiatric condition affecting 1-3% of the population. Typically, symptoms start in adolescence or early adulthood, are time-consuming, and have a significant impact on quality of…
- Trial name
- NEUROCOMP (NCT06566781)
- Where
- Portugal
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Fundacao Champalimaud
Body Dysmorphic Disorder, Obsessive-compulsive Disorder
Oxytocin Administration in BDD and OCD
The purpose of the current study is to investigate the effect of an acute administration of intranasal oxytocin, relative to placebo, on social cognitive impairments among individuals with body dysmorphic disorder and…
- Trial name
- NCT02671266
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Depression - Major Depressive Disorder, Anxiety Chronic
The Effectiveness and Efficacy of an Online Cognitive Behavioral Psychotherapeutic Program
An online group cognitive behavioral psychotherapeutic program will be offered to patients with cystic fibrosis and to caregivers by the Hellenic Cystic Fibrosis Association.
- Conditions
- Depression - Major Depressive Disorder, Anxiety Chronic, Anxiety, Functional Outcome
- Trial name
- RAKITZIHCFA (NCT07255131)
- Testing
- Group A An online group cognitive behavioral psychotherapy in 13 sessions via Zoom, Group B An online group supportive psychotherapy in 13 sessions via Zoom, Group C An online group cognitive behavioral psychotherapy in 13 sessions via Zoom
- Where
- Greece
- Volunteers
- 52 people
- Sponsor
- Rakitzi, Stavroula
Skin-Picking
Skin Picking Approach Avoidance Task
Pathological skin picking (PSP) is conceptualized as a behavioral addiction. Research has shown that behavioral addictions (e.g., problematic alcoholism or smoking) can be reduced using a cognitive retraining tool called…
- Trial name
- SPAAT (NCT04099537)
- Testing
- Computerized cognitive training
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Wisconsin, Milwaukee
Obsessive-compulsive Disorders and Symptoms, Obsessive Thoughts
Internet-delivered CBM-C for OC-symptoms
A factorial randomised controlled trial comparing internet-delivered combined cognitive bias modification intervention (iCBM-C) versus internet-delivered CBM-interpretation intervention (iCBM-I), internet-delivered CBM-attention…
- Conditions
- Obsessive-compulsive Disorders and Symptoms, Obsessive Thoughts, Obsessive Compulsive Behavior
- Trial name
- NCT04575805
- Testing
- Internet-delivered Combined Cognitive Bias Modification (iCBM-C), Internet-delivered Cognitive Bias Modification-Interpretation (iCBM-I), Internet-delivered Cognitive Bias Modification-Attention (iCBM-A)
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Dokuz Eylul University
Obsessive-Compulsive Disorder
Dealing With Intrusive Thoughts in OCD - a Comparison of Detached Mindfulness and Cognitive Restructuring
The purpose of this study is to assess and compare the overall efficacy and differential effects of detached mindfulness and cognitive restructuring in the treatment of patients with obsessive-compulsive disorder.
- Trial name
- NCT03002753
- Testing
- detached mindfulness, cognitive restructuring
- Where
- Germany
- Volunteers
- 43 people
- Sponsor
- Christoph-Dornier-Stiftung für Klinische Psychologie
Obsessive Compulsive Disorders
Repetitive Transcranial Magnetic Stimulation in the Treatment of Obsessive Compulsive Disorders
Objectives.-Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive stimulation methods that became widely used as therapeutic tools in neuropsychiatric research.
- Trial name
- rTMS-OCD (NCT02511392)
- Testing
- rTMS-1Hz, rTMS-10 Hz
- Volunteers
- 45 people
- Sponsor
- Assiut University
Hoarding Disorder
A Test of Acceptance-based Bibliotherapy for Hoarding Disorder
The investigators are proposing to test an Acceptance and Commitment Therapy (ACT) based bibliotherapy intervention as a self-help approach to hoarding disorder.
- Trial name
- NCT07880236
- Testing
- Acceptance and Commitment Therapy Bibliotherapy
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Utah State University
Obsessive-Compulsive Disorder in Children, Obsessive-Compulsive Disorder in Adolescence
Treatment Effects of Family Based Cognitive Therapy in Children and Adolescents With Obsessive Compulsive Disorder
To investigate the benefits and harms, and the neural and neurocognitive mediators of treatment response, in family-based cognitive behavioural therapy versus family-based psychoeducation and relaxation training in children and…
- Trial name
- TECTO (NCT03595098)
- Testing
- Family Based Cognitive Behavioural Therapy, Family Based Psychoeducation/Relaxation Training
- Where
- Denmark
- Volunteers
- 128 people
- Sponsor
- Anne Katrine Pagsberg
Obsessive-Compulsive Disorder
Safety and Efficacy of Pramipexole Treatment in Resistant Obsessive-Compulsive Disorder (OCD)
The most common and effective treatment for OCD is pharmacological therapy that includes selective serotonin reuptake inhibitors (SSRIs) antidepressants and, in the case of patients resistant to this approach, a combination with…
- Trial name
- OCD-RT (NCT06611592)
- Testing
- Pramipexole 0.088mg/tid, Pramipexole 0.18 mg/tid, Pramipexole 0.35 mg/tid
- Where
- Portugal
- Volunteers
- 48 people
- Sponsor
- Clinical Academic Center (2CA-Braga)
Obsessive Compulsive Disorder
Attaining and Maintaining Wellness in Obsessive-compulsive Disorder
The goal of this study is to understand whether patients with obsessive-compulsive disorder (OCD) already on serotonin reuptake inhibitors (SRIs) who then receive a type of Cognitive-behavioral therapy called Exposure and Ritual…
- Trial name
- NCT01686087
- Testing
- Monthly Booster Sessions of EX/RP, Visits with MD and independent evaluators
- Where
- 2 sites in United States
- Volunteers
- 137 people
- Sponsor
- New York State Psychiatric Institute
Obsessive - Compulsive Disorder
Feasibility and Efficacy Trial of a Culturally Adapted Guided Self-Help CBT Manual for OCD
This randomised controlled trial (RCT) aims to assess the feasibility, acceptability, and preliminary efficacy of a culturally adapted, guided self-help cognitive behaviour therapy (CBT) manual specifically designed for…
- Trial name
- NCT07239401
- Testing
- Culturally adapted Guided Self-Help OCD Manual
- Volunteers
- 108 people
- Sponsor
- Pakistan Association of Cognitive Therapists
Obsessive Compulsive Disorder
Application of Vagal Stimulation in Exposure and Response Prevention for Obsessive Compulsive Disorder
Obsessive Compulsive Disorder (OCD) is a condition associated with recurrent intrusive distressing thoughts, images and urges compelling the person to perform neutralizing acts or thoughts to the extent of significantly…
- Trial name
- NCT02196090
- Testing
- Exposure and Response Prevention, Cold face gel mask
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- King's College London
Obsessive-Compulsive Disorder, OCD
pBFS Guided High-dose rTMS Therapy for Treatment-Resistant Obsessive-Compulsive Disorder
The research aims to evaluate the safety and efficacy of pBFS-guided High-dose rTMS therapy targeting preSMA for patients with treatment-resistant Obsessive-Compulsive Disorder.
- Trial name
- NCT05964062
- Testing
- active rTMS treatment
- Volunteers
- 30 people
- Sponsor
- Changping Laboratory
Obsessive Compulsive Disorder
China Refractory Obsessive-Compulsive Disorder Deep Brain Stimulation Study
Refractory obsessive-compulsive disorder (OCD) is a disabling condition. Deep brain stimulation (DBS) of the nucleus accumbens is the most tested therapeutic avenue for refractory OCD.
- Trial name
- CRODS (NCT02398318)
- Testing
- Bilateral Nucleus Accumbens DBS (Suzhou Sceneray)
- Where
- 3 sites in China
- Sponsor
- Ruijin Hospital
OCD
Personalized Inhibitory Control Training for Compulsive Behavior Change
Obsessive-compulsive disorder (OCD) is a severe mental illness characterized by repetitive behaviors that a person feels compelled to perform.
- Trial name
- NCT03682913
- Testing
- P-CIT protocol
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hebrew University of Jerusalem
Obsessive - Compulsive Disorder
The Study is Investigating the Effectiveness of the Traditional Islamically Integrated Psychotherapy Using the Islamic Workbook for Religious Obsessive-Compulsive Disorder in Turkish Adults Who Suffer From Scrupulosity
The goal of the clinical trial is to determine whether the Islamic Workbook of Scrupulosity treats scrupulosity in adults. The main question is whether patients show fewer scrupulosity symptoms after receiving the workbook…
- Trial name
- TIIP (NCT07872462)
- Testing
- Islamically integrated cognitive behavioral intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people
- Sponsor
- Ibn Haldun University