Clinical trials: Ocd
Obsessive-Compulsive Disorder
Pragmatic Trial of Obsessive-compulsive Disorder
This study includes a sequenced clinical trial in order to assess the efficacy of several switching or augment strategies when initial treatment is ineffective，and to provide strong evidence for clinical practice and…
- Trial name
- Proceed (NCT04539951)
- Testing
- Sertraline 200 milligram(mg), Sertraline 300 milligram(mg), Fluvoxamine
- Where
- China
- Volunteers
- 1,600 people
- Sponsor
- Shanghai Mental Health Center
Cartilage or Osteochondral Defects in the Knee
Agili-C™ Implant Performance Evaluation in the Repair of Cartilage and Osteochondral Defects
Evaluate the performance of the Agili-C™ in the repair of Cartilage and Osteochondral defects.
- Trial name
- NCT02423629
- Testing
- Agili-C™ implantation procedure
- Where
- 8 sites in Austria, Belgium and 6 more
- Volunteers
- 143 people
- Sponsor
- Smith & Nephew, Inc.
Obsessive-Compulsive Disorder
Feasibility, Clinical Effects, and Safety of Psilocybin-assisted Psychotherapy for Treatment-resistant OCD
Psilocybin, the chemical component of "magic mushrooms", has been administered with psychotherapy in several randomized clinical trials (RCTs) showing large and sustained antidepressant effects.
- Trial name
- PAP-OCD (NCT06299319)
- Testing
- Psilocybin
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Centre for Addiction and Mental Health
Obsessive-Complusive Disorder
Analysis of Visual-Motor Task Electrophysiological Activity During Deep Brain Stimulation for Treatment-Resistant Movement Disorders
Objective The objective of this pilot study is to characterize the abnormal neuronal firing patterns of basal ganglia neurons and those in the premotor cortex in patients with treatment-resistant movement disorders undergoing…
- Trial name
- NCT01485263
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Major Depressive Disorder, Bi-Polar Disorder
DELPhI Evaluation of Psychiatric Conditions
DELPhI acquisition and analysis software, a QuantalX Neuroscience development, which is designed to measure, analyze, and display brain electrical activity of human electroencephalogram (EEG), to transcranial magnetic stimulation…
- Conditions
- Major Depressive Disorder, Bi-Polar Disorder, ADHD, Schizophrenia
- Trial name
- NCT03842345
- Sponsor
- QuantalX Neuroscience
Obsessive-Compulsive Disorder
ESTOCMA: Mental Health Application for Enhancing Mental Health Literacy About Obsessive-compulsive Disorder
The aim of the study is to analyze the efficacy of a mobile health application (app) designed to increase mental health literacy, help seeking attitudes and reduce stigma associated with obsessive-compulsive disorder.
- Trial name
- ESTOCMA (NCT04777292)
- Testing
- Use of a mobile health application until app completion
- Where
- Spain
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Neurotic Excoriation, Pathologic Skin Picking
Double-Blind Lamictal (Lamotrigine) in Neurotic Excoriation
The goal of the proposed study is to evaluate the comparative efficacy of Lamictal (lamotrigine) to placebo in neurotic excoriation.
- Conditions
- Neurotic Excoriation, Pathologic Skin Picking, Psychogenic Excoriation, Dermatillomania
- Trial name
- NCT00513019
- Testing
- Lamictal (lamotrigine)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Chicago
Tourette's Syndrome, Obsessive Compulsive Disorder
Evaluation of the HBDL Coil Transcranial Magnetic Stimulation (TMS) Device - Safety and Feasibility Study for the Treatment of Tourette Syndrome
This is an open study.approximately 20 patients diagnosed with tourette's syndrome and under pharmAcological or psychotherapy treatments will participate.patients will be recruited from Schneider hospital and all his extensions.
- Trial name
- NCT00965211
- Testing
- HBDL-coil Repetitive Deep Transcranial magnetic stimulation (rdTMS)
- Where
- 2 sites in Israel
- Volunteers
- 20 people
- Sponsor
- Shalvata Mental Health Center
Obsessive Compulsive Disorder, Body Dysmorphic Disorder
Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals
To examine the effectiveness and clinical care outcomes of cognitive-behavioral therapy interventions at Massachusetts General Hospital (MGH).
- Conditions
- Obsessive Compulsive Disorder, Body Dysmorphic Disorder, Tourette Syndrome, Trichotillomania
- Trial name
- NCT01075672
- Testing
- Cognitive behavioral therapy (CBT)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Massachusetts General Hospital
Anxiety Disorders, OCD
Digital Coach to Support Exposure Therapy Homework for Anxious Youth
This study is testing a digital tool called BraveBot for young people who are receiving cognitive behavioral therapy (CBT) for anxiety, OCD, or related problems. BraveBot is a computer program, not a person.
- Trial name
- NCT07666672
- Testing
- BraveBot, Self-Guided Exposure Therapy Homework
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Obsessive Compulsive Disorder
Long-term Safety Study of Adjunctive Troriluzole in Subjects With Obsessive Compulsive Disorder
The purpose of the study is to evaluate the long term safety and tolerability of troriluzole as adjunctive therapy in subjects with obsessive compulsive disorder (OCD).
- Trial name
- NCT04708834
- Testing
- Troriluzole (BHV-4157)
- Where
- 175 sites in United States, Canada and 4 more
- Volunteers
- 772 people
- Sponsor
- Biohaven Pharmaceuticals, Inc.
Obsessive-Compulsive Disorder
The Safety and Efficacy of Long-term Treatment of PINS Stimulator System for Patients With Obsessive-Compulsive Disorder
The purpose of this clinical study is To verify the long term effectiveness and safety of a bilateral deep brain stimulation (DBS) produced by Beijing PINS Medical Co., Ltd.
- Trial name
- NCT02253472
- Testing
- Deep Brain Stimulation
- Volunteers
- 30 people
- Sponsor
- Beijing Pins Medical Co., Ltd
Obsessive Compulsive Disorder
Precision Analytic Research Methods in OCD
Psychiatric disorders characterized by compulsivity, such as obsessive-compulsive disorder (OCD), result in considerable functional impairment and many individuals do not respond to gold-standard treatments.
- Trial name
- NCT07011901
- Testing
- Exposure and Response Prevention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Patient Diagnosed With OCD and Resistant to SSRI Treatment, Failed SSRI Over 12 Weeks at Appropriate Doses
Study to Evaluate the Effect of AFQ056 in Obsessive Compulsive Disorder (OCD) Patients Resistant to Selective Serotonin Reuptake Inhibitor (SSRI) Therapy
The purpose of this study is to determine whether AFQ056 as an add on therapy to SSRIs can have beneficial effects by reducing the total score of Y-BOCS (Yale and Brown Obsessive Compulsive Scale) in OCD patients resistant to…
- Trial name
- NCT01813019
- Testing
- AFQ056
- Where
- 15 sites in United States, Bulgaria and 3 more
- Volunteers
- 50 people
- Sponsor
- Novartis Pharmaceuticals
Parkinson's Disease, Obsessive-Compulsive Disorder
Mechanisms of Fronto-Subcortical Dysfunction: Comparing PD and OCD
The purpose of this study is to characterize and compare irregularities in dopaminergic function in fronto-subcortical circuits, between Parkinson's Disease patients (ON and OFF medication) and patients with obsessive-compulsive…
- Trial name
- NCT00790634
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Obsessive-Compulsive Disorder
Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Obsessive Compulsive Disorder
This study will evaluate the possible therapeutic effects of repetitive transcranial magnetic stimulation(rTMS) in obsessive-compulsive disorder (OCD) in OCD patients who have not fully responded to pharmacotherapy, and the…
- Trial name
- NCT03649685
- Testing
- Continuous theta burst stimulation (cTBS)
- Where
- China
- Volunteers
- 53 people
- Sponsor
- Shanghai Mental Health Center
Obsessive - Compulsive Disorder, Tic Disorder, Chronic Motor or Vocal
Integrating Exposure and Response Prevention and Habit Reversal Techniques to Treat a Tourettic Subtype of Obsessive-Compulsive Disorder (Tourettic OCD)
Obsessive-Compulsive Disorder and Tic Disorders frequently co-occur, and a subgroup of patients - those with a Tourettic Subtype of OCD (TOCD) - present with concurrent obsessive-compulsive and tic symptoms.
- Conditions
- Obsessive - Compulsive Disorder, Tic Disorder, Chronic Motor or Vocal, Tic Disorders, Tic Disorder, Combined Vocal and Multiple Motor
- Trial name
- TORCH (NCT07725926)
- Testing
- Exposure and Response Prevention (ERP), Habit Reversal Training (HbRT, Psychoeducation and Supportive Intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 40 people
- Sponsor
- University College London Hospitals
Obsessive-Compulsive Disorder
Pilot Study of Ketamine in Adults With Obsessive-Compulsive Disorder (OCD)
In this study investigators are studying the effects of a drug called ketamine on the symptoms of Obsessive-compulsive disorder (OCD).
- Trial name
- NCT01100255
- Testing
- Ketamine infusion, Saline
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- New York State Psychiatric Institute
Obsessive-Compulsive Disorder
Accelerated Rotational Field Deep TMS for Treating OCD
A Prospective Double Blind Randomized Controlled Trial to Evaluate the Efficacy and Durability of the BrainsWay Rotational Field Deep Transcranial Magnetic Stimulation (Deep TMS) in Obsessive-Compulsive Subjects
- Trial name
- NCT07116785
- Testing
- BrainsWay Deep TMS HAC/H7-Coil
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Ben-Gurion University of the Negev
Compulsive Behavior, Obsessive-Compulsive Disorder
Theta Burst Stimulation Plus Habit Override Training for Compulsive Behaviors
This project seeks to identify causal neural mechanisms underlying unwanted, repetitive behaviors (compulsions). Using non-invasive brain stimulation coupled with practice in a computer task, we will modulate activity in a target…
- Trial name
- NCT04580043
- Testing
- Habit Override Practice, Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Rebecca Price