Clinical trials: Ocd
Obsessive Compulsive Disorder (OCD)
Reducing Maximal Support in OCD: Efficacy of Stepped-Care Online CBT
This study is conducted to explore the efficacy and cost-effectiveness of stepped-care internet-based cognitive behavior therapy (sc-ICBT) with reduced support compared to cognitive-behavioral group therapy(CBGT), to identify the…
- Trial name
- NCT06659094
- Testing
- stepped-care Internet-based cognitive behavioral therapy(SC-ICBT), Cognitive Behavioral Group Therapy (CBGT), conventional medical treatment (TAU)
- Where
- China
- Volunteers
- 95 people
- Sponsor
- Shanghai Mental Health Center
Obsessive Compulsive Disorder
Assessing the Effects of a Neurobehavioral Intervention on Symptoms of Obsessive Compulsive Disorder
This experiment will examine if the use of computerized tasks that train individuals to control their attention more effectively will predict individual differences in obsessive-compulsive symptoms, rumination and BDNF change.
- Trial name
- CCT-OC (NCT01414023)
- Testing
- Cognitive Control Training, Peripheral Vision Task
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Obsessive-Compulsive Disorder
Development of Adaptive Deep Brain Stimulation for OCD (Phase 1a)
This research study is for participants that have been diagnosed with intractable Obsessive -compulsive disorder (OCD). OCD is a persistent and oftentimes disabling disorder marked by unwanted and distressing thoughts…
- Trial name
- NCT03457675
- Testing
- Activa PC+S DBS implant for OCD, One Month Blinded Discontinuation Period
- Where
- 3 sites in United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Obsessive-Compulsive Disorder
Study of Memantine Augmentation in Severe Obsessive-Compulsive Disorder
Memantine is a glutamate receptor antagonist that has been reported to reduce Obsessive-Compulsive Disorder (OCD) symptoms in case studies of treatment-resistant individuals.
- Trial name
- NCT00869505
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Obsessive-Compulsive Disorder
Towards Personalized Medicine for OCD
Obsessive compulsive disorder (OCD) is one of the most disabling anxiety disorders occurring in about 2 out of a 100 adults. Untreated, OCD is a chronic and deteriorating condition, negatively impacting multiple areas of life…
- Trial name
- NCT03852186
- Testing
- Cognitive behavioral therapy, Acceptance and commitment therapy
- Where
- Denmark
- Volunteers
- 178 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Tourette's Disorder
Omega-3 Fatty Acids in Tourette's Disorder
This study examines the safety and efficacy of omega-3 fatty acids (fish oil) for the treatment of Tourette's Disorder.
- Trial name
- NCT01315327
- Testing
- Omega-3 Fatty Acids, Olive oil
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- NYU Langone Health
Obsessive Compulsive Disorder
Intravenous Ketamine in the Treatment of Obsessive-Compulsive Disorder
Obsessive-Compulsive Disorder (OCD) is a chronic and disabling anxiety disorder and a leading cause of worldwide disability that presents a significant public health problem.
- Trial name
- IVKetamine (NCT01371110)
- Testing
- Ketamine, Midazolam
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Wayne Goodman MD
Obsessive Compulsive Disorder (OCD), Treatment Resistant Obsessive Compulsive Disorder
Brain-Oscillation Synchronized Stimulation of the DMPFC
This trial aims to obtain initial evidence about the clinical efficacy and modulation of neurophysiological markers in obsessive compulsive disorder (OCD) using personalized (i.e., electroencephalography (EEG)-triggered)…
- Trial name
- BOSS-OCD (NCT06942559)
- Testing
- EEG-Triggered Repetitive Transcranial Magnetic Stimulation (rTMS), Non-EEG Triggered Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Centre for Addiction and Mental Health
Parkinson Disease, Essential Tremor
Functional Magnetic Resonance Imaging (fMRI) During Deep Brain Stimulation (DBS) to Treat Parkinson's Disease
This study is investigating the usefulness of using functional magnetic resonance imaging (fMRI) to monitor brain activation during deep brain stimulation for Parkinson's Disease, Essential tremor, dystonia, OCD, depression…
- Conditions
- Parkinson Disease, Essential Tremor, Dystonia, Obsessive Compulsive Disorder
- Trial name
- NCT01809613
- Testing
- Functional Magnetic Resonance Imaging (fMRI)
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Mayo Clinic
Trichotillomania
Trichotillomania: Group Cognitive-Behavioral Therapy
Objective: Trichotillomania is a psychiatric condition characterized by chronic pulling and plucking of one's own hair. Cognitive behavioral therapy shows promise as a treatment.
- Trial name
- NCT01968343
- Testing
- Cognitive-behavioral therapy., Supportive therapy.
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- University of Sao Paulo
Obsessive-Compulsive Disorder
Probiotic Treatment in Adult Obsessive-Compulsive Disorder
This study will evaluate the effectiveness of 12-weeks of probiotic treatment in adults with primary Obsessive-Compulsive Disorder and whether this treatment will alter the microbiota composition in these patients.
- Trial name
- NCT02334644
- Testing
- Probiotic Formula (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175)
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- McMaster University
Skin Picking
Impact of COVID-19 on Mental Health of Patients With Skin Picking
Skin Picking Disorder (SPD) affects up to 10% of the general population, causing significant socioeconomic damage in 75% of affected individuals.
- Trial name
- NCT04522492
- Testing
- Internet-based Cognitive Behavioral Therapy, Quality of life promotion
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Juvenile Osteochondritis Dissecans
Study of Two Surgical Drilling Techniques to Treat Juvenile Osteochondritis Dissecans of the Knee
The purpose of this study is to compare the functional, clinical and radiographic outcomes associated with trans-articular drilling versus retro-articular drilling, two commonly employed techniques of operative treatment for…
- Trial name
- NCT01754298
- Testing
- Retro-articular drilling, Trans-articular drilling
- Where
- 14 sites in United States, Canada
- Volunteers
- 91 people
- Sponsor
- Boston Children's Hospital
Obsessive-Compulsive Disorder
Psychiatric Neurosurgery (PNS) for Obsessive Compulsive Disorder (OCD): A Qualitative Analysis of Patient and Family Member Experiences
In this study the investigators will use semi-structured interviews to qualitatively analyse patient and family member experiences with either deep brain stimulation or other forms of psychiatric neurosurgery.
- Trial name
- NCT02537795
- Testing
- deep brain stimulation, anterior capsulotomy
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Osteochondral Defects of Talus, Gait Analysis
Gait Pattern Analysis After Arthroscopic Treament of Osteochondral Defects of Talus
The study will investigate alterations in post-surgical gait patterns among patients who have undergone all arthroscopic microfracture and biological scaffold implementation surgery for the osteochondral lesions of talus.
- Conditions
- Osteochondral Defects of Talus, Gait Analysis, Microfracture Procedure, Biological Scaffold
- Trial name
- NCT07161128
- Testing
- arthroscopic microfracture and biological scaffold implementation for osteochondral defects of talus
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gazi University
Obsessive-Compulsive Disorder
SMART ERP for the Behavioral Treatment of Youth With Obsessive Compulsive Disorder (OCD)
This randomized pilot study examines a graduated behavioral treatment approach for youth with obsessive compulsive disorder. Youth will be randomized to receive treatment in the community or at the hospital.
- Trial name
- NCT03672565
- Testing
- Phase One: Standardized Brief Intensive ERP, Phase Two: Flexible Patient Driven Intensive ERP, Follow-Up Phase: Booster Calls
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of British Columbia
Emotion Regulation, Mood Disorders
Neurostimulation Versus Therapy for Problems With Emotions
The primary goal of this clinical trial is to evaluate the unique neural and behavioral effects of a one-session training combining emotion regulation skills training, with excitatory repetitive transcranial magnetic stimulation…
- Conditions
- Emotion Regulation, Mood Disorders, Stress Disorder, Anxiety Disorders
- Trial name
- NCT05712057
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), electrical scalp stimulation, Cognitive Restructuring
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Duke University
Obsessive-Compulsive Disorder
Repetitive Transcranial Magnetic Stimulation in Obsessive Compulsive Disorder
Evaluate the therapeutic effect of a functional Magnetic Resonance Imaging (fMRI)-guided and robotized neuronavigated theta burst Transcranial Magnetic Stimulation (TMS) targeting right inferior frontal region in resistant…
- Trial name
- MAGTOC (NCT02884674)
- Testing
- Active Repetitive Transcranial Magnetic Stimulation
- Where
- France
- Volunteers
- 56 people
- Sponsor
- University Hospital, Grenoble
Obsessive-Compulsive Disorder
Double Blinded, Placebo-Controlled Trial of Paliperidone Addition in SRI-Resistant Obsessive-Compulsive Disorder
Obsessive-compulsive disorder (OCD) is a common, chronic, and oftentimes disabling disorder. The only established treatments for OCD are a specific form of Cognitive Behavioral Therapy (CBT) and the Serotonin Reuptake Inhibitor…
- Trial name
- NCT00632229
- Testing
- Paliperidone
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- University of South Florida
Obsessive-Compulsive Disorder
Individually Targeted Neuromodulation for Contamination-based OCD
Patients with obsessive-compulsive disorder (OCD) experience a wide array of different types of obsessions and compulsions. However, current treatments for OCD employ a "one size fits all" approach and are used for all patients…
- Trial name
- NCT05048251
- Testing
- cTBS, iTBS
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mclean Hospital