Clinical trials: Ocd
Obsessive-Compulsive Disorder
Targeting Taboo Thoughts In Obsessive-Compulsive Disorder
The purpose of this pilot study is to investigate if a cognitive treatment targeting obsessive beliefs in patients with aggressive obsessions is feasible and effective as an online treatment.
- Trial name
- NCT04313439
- Testing
- Online cognitive therapy (I-CT)
- Where
- Sweden
- Volunteers
- 19 people
- Sponsor
- Karolinska Institutet
Obsessive Compulsive Disorder (OCD)
Safety Study of the Drug RG1068 in Patients With Obsessive Compulsive Disorder
The purpose of this study is to determine the safety and tolerability of RG1068 (Synthetic Human Secretin) when administered three times weekly to outpatients with obsessive compulsive disorder (OCD), to determine the impact of…
- Trial name
- NCT00216294
- Testing
- RG1068 (Synthetic Human Secretin)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Indiana University
Obsessive-Compulsive Disorder
Family Focused Treatment of Pediatric Obsessive Compulsive Disorder
Pediatric obsessive compulsive disorder (OCD) is a chronic, impairing condition that accrues significant concurrent and long-term risk to affected youth (Piacentini et al. 2003; Pine et al. 1998).
- Trial name
- PFIT (NCT01409642)
- Testing
- Individual Child CBT, Positive Family Interaction Therapy
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of California, Los Angeles
Hoarding Disorder
Contingency Management for Hoarding Disorder
Aim 1: To test the efficacy of contingency management for patients with hoarding disorder (HD). Hypothesis 1. Participants completing CM will show significant pre- to post-treatment decreases in severity of hoarding symptoms and…
- Trial name
- HCM (NCT04894851)
- Testing
- Contingency Management
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Hartford Hospital
Obsessive-Compulsive Disorder
Valbenazine in Obsessive Compulsive Disorder
The primary aim of the study is to examine the efficacy and safety of valbenazine in adults with moderate to severe obsessive-compulsive disorder (OCD).
- Trial name
- NCT07111988
- Testing
- Valbenazine
- Volunteers
- 30 people
- Sponsor
- University of Chicago
Obsessive-Compulsive Disorder
Exposure and Response Prevention Therapy for Obsessive-compulsive Disorder
The purpose of this research study is to evaluate whether Exposure and Response Prevention Therapy (ERP) can help adults with obsessive-compulsive disorder (OCD) in China following a training of professionals and ongoing…
- Trial name
- NCT02602886
- Testing
- Exposure and Response Prevention Therapy
- Where
- 5 sites in China
- Volunteers
- 48 people
- Sponsor
- Ruijin Hospital
Trichotillomania
N-Acetyl Cysteine in Trichotillomania
This is a 12-week, double-blind study of N-Acetyl Cysteine in the treatment of trichotillomania
- Trial name
- NCT00354770
- Testing
- N-Acetyl Cysteine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Chicago
Trichotillomania (Hair-Pulling Disorder), Trichotillomania
Semaglutide (Wegovy) Treatment for Trichotillomania
This research study is testing the effectiveness and safety of semaglutide (Wegovy) in people with trichotillomania, also known as hair-pulling disorder.
- Conditions
- Trichotillomania (Hair-Pulling Disorder), Trichotillomania, Hair Pulling Disorder, Hair Pulling
- Trial name
- NCT07282769
- Testing
- Semaglutide
- Volunteers
- 10 people
- Sponsor
- University of Chicago
Obsessive-Compulsive Disorder
Acceptance and Commitment Therapy in SSRI-Resistant Obsessive Compulsive Disorder
The purpose of this study is to determine whether acceptance and commitment therapy is effective in the treatment of SSRIs-resistant obsessive- compulsive disorder.
- Trial name
- NCT02955654
- Testing
- Acceptance and commitment therapy, Aripiprazole, Stress management training
- Sponsor
- Shanghai Mental Health Center
ADHD, Trichotillomania
Methylphenidate in ADHD With Trichotillomania
This study will evaluate the safety and effectiveness of methylphenidate in treating attention deficit hyperactivity disorder (ADHD) in children with both ADHD and trichotillomania.
- Trial name
- NCT00552266
- Testing
- Methylphenidate
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Geha Mental Health Center
OCD, Obsessive-Compulsive Disorder
Measuring Automated Behavioral Observations & Vocal Expressions (ABOVE)
The investigators propose to synchronize automated measurements of behavior - head, body, and face dynamics, gaze, and vocal prosody - with simultaneous recordings of brain activity in clinically relevant contexts.
- Trial name
- ABOVE (NCT03459456)
- Testing
- Provocation OC task (Provoc), Trier Social Stress Test (TSST), Exposure provocation task
- Where
- 3 sites in United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Obsessive-Compulsive Disorder/High Compulsive Individuals, Healthy Individuals
The Role of Serotonin in Compulsive Behavior in Humans: Underlying Brain Mechanisms
The aim of this project is to investigate: The status of the central serotonin (5-hydroxytryptamine, 5-HT) system in compulsive behaviour and how it is affected by sub-chronic escitalopram administration The mechanisms underlying…
- Trial name
- NCT04336228
- Testing
- Escitalopram
- Where
- Denmark
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Obsessive - Compulsive Disorder
Accelerated rTMS in Hospitalized Patients With OCD: a Feasibility and Mechanistic Study
This study investigates a new treatment approach for Obsessive-Compulsive Disorder (OCD), a condition characterized by unwanted repetitive thoughts and behaviors.
- Trial name
- arTMS-OCD (NCT07135414)
- Testing
- iTBS, dTMS, ERP
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- University Hospital, Ghent
OCD - Osteochondritis Dissecans
MRI Findings of Epiphyseal Growth Plate in Healthy Children
The purpose of the study is to determine if by using MRI changes can be identified changes early on in the knees of young children that may be at risk for developing osteochondritis dissecans.
- Trial name
- NCT03190200
- Testing
- MRI
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Obsessive-Compulsive Disorder
Using Personalized Assessments in the Treatment of Childhood OCD
The primary purpose of this study is to learn whether personalized assessment of obsessive-compulsive disorder (OCD) symptoms in childhood OCD using mobile health technology are feasible and acceptable for youth and parents.
- Trial name
- NCT06407648
- Testing
- Personalized Assessments, Standard of Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Johns Hopkins University
Autism Spectrum Disorders, Autism
Psychotherapy for Anxiety in Children With Autism Spectrum Disorder
Anxiety disorders affect 40 to 50% of children with autism spectrum disorders (ASD), contributing to substantial distress and impairment.
- Conditions
- Autism Spectrum Disorders, Autism, Asperger's Syndrome, Pervasive Developmental Disability - Not Otherwise Specified
- Trial name
- TAASD (NCT02028247)
- Testing
- Personalized Cognitive-behavioral therapy, Standard Practice Cognitive-behavioral therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of South Florida
OCD, Decision-Making
Arbitration Between Habitual and Goal-directed Behavior in Obsessive-compulsive Disorder: Circuit Dynamics and Effects of Noninvasive Neurostimulation
People utilize two behavioral strategies, goal-directed and habitual, when engaging in value-based decision-making that involves rewarding or punishing outcomes.
- Conditions
- OCD, Decision-Making, tDCS, fMRI
- Trial name
- NCT04075890
- Testing
- transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Obsessive Compulsive Disorder
Neural Mechanisms of CBT Response in Hoarding Disorder
The purpose of this research is to measure changes in brain activity with functional magnetic resonance imaging (fMRI) before and after cognitive-behavioral therapy for compulsive hoarding.
- Trial name
- NCT01956344
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Skin-Picking, Trichotillomania (Hair-Pulling Disorder)
Behavioral Treatment and Memantine in Body Focused Repetitive Behaviors
The goal of the proposed study is to compare the efficacy of behavioral treatment (BT) to memantine, a psychopharmacological agent, for BFRBs.
- Trial name
- NCT05796752
- Testing
- Memantine, ComB Behavioral Therapy
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Chicago
Obsessive-Compulsive Disorder, EEG With Periodic Abnormalities
EEG Results of Deep TMS in Patients With OCD
Obsessive Compulsive Disorder (OCD) is a psychiatric disorder in which involuntary thoughts and irresistible behaviors are seen and its prevalence affects 2%-3% of the general population.
- Trial name
- NCT05188833
- Testing
- Deep Transcranial Magnetic Stimulation, Paroxetine
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital