Clinical trials: Ocd
OCD
Effect of Pyridoxine as Add-on Therapy in OCD Patients
Title: Effect of Pyridoxine as Add-on Therapy with Standard Treatment in Obsessive Compulsive Disorder Patients: A Randomized, Double-Blind, Placebo-Controlled Trial Purpose of the study: This study aims to examine the effect of…
- Trial name
- NCT06244121
- Testing
- Pyridoxine
- Where
- Bangladesh
- Volunteers
- 76 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Obsessive-compulsive Disorder With Acute Onset, PANDAS
PANS - A Detailed Study of the Patients, Their Symptoms, Biomarkers and Treatment Offered in a Scandinavian Cohort
Background: Obsessive-compulsive disorder (OCD) is considered one of the most debilitating of the psychiatric illnesses, yet much remains unclear regarding causes and cures.
- Conditions
- Obsessive-compulsive Disorder With Acute Onset, PANDAS, Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections, Pediatric Acute-onset Neuropsychiatric Syndrome (PANS)
- Trial name
- NCT02190292
- Where
- Sweden
- Volunteers
- 185 people
- Sponsor
- Karolinska Institutet
OCD
Pilot Study to Evaluate Escitalopram in Obsessive-compulsive Disorder
This study will determine the safety and effectiveness of escitalopram (Lexapro)in treating obsessive-compulsive disorder (OCD) symptoms.
- Trial name
- NCT00215137
- Testing
- escitalopram
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Duke University
Obsessive Compulsive Disorder
Efficacy Study of Transcranial Magnetic Stimulation for Treatment of Obsessive-Compulsive Disorder
This study aimed at verifying whether sessions of repetitive transcranial magnetic stimulation over a certain brain area (the supplementary motor area) could be useful in the relief of Obsessive-Compulsive Disorder symptoms.
- Trial name
- NCT01540305
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Brazil
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Brasilia
Obsessive-Compulsive Disorder
Double Blinded, Placebo-Controlled Trial of Paliperidone Addition in SRI-Resistant Obsessive-Compulsive Disorder
Obsessive-compulsive disorder (OCD) is a common, chronic, and oftentimes disabling disorder. The only established treatments for OCD are a specific form of Cognitive Behavioral Therapy (CBT) and the Serotonin Reuptake Inhibitor…
- Trial name
- NCT00632229
- Testing
- Paliperidone
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- University of South Florida
Obsessive-Compulsive Disorder, Post Traumatic Stress Disorder
CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy
Anxiety-, obsessive-compulsive and trauma- and stressor-related disorders reflect a significant public health problem. This study is designed to evaluate the predictive power of a novel biomarker based on a CO2 challenge, thus…
- Conditions
- Obsessive-Compulsive Disorder, Post Traumatic Stress Disorder, Generalized Anxiety Disorder, Social Anxiety Disorder
- Trial name
- NCT05467683
- Testing
- Exposure-Based Therapy
- Where
- 2 sites in United States
- Volunteers
- 600 people
- Sponsor
- Jasper A. Smits
Mental Disorders, Severe
Measuring Development of Brain Responses to Vocal Sounds in Babies of Mums With Mental Illness
CAPRI-Voc examines the differences in how speech and environmental sounds are processed in the infant brain as they grow from 9 to 12 months.
- Trial name
- CAPRI-Voc (NCT04350294)
- Where
- United Kingdom
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Anxiety, Obsessive-Compulsive Disorder
Virtual Reality System for Anxiety and OCD
Cognitive Behavioral Therapy with fear provoking exposures is the most effective therapy for anxiety disorders. The investigators aim to enhance this therapy with the use of virtual reality exposures.
- Trial name
- NCT03636022
- Testing
- VR System, Control
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Minnesota HealthSolutions
Post-Traumatic Stress Disorders, Obsessive-Compulsive Disorder
Cognitive Characteristics of PTSD Patients With OCD
Cognitive profile of patients who suffer both from PTSD and OCD, as compared to those who suffer from PTSD or OCD without other comorbidity.
- Trial name
- NCT00294970
- Where
- Israel
- Volunteers
- 76 people
- Sponsor
- Sheba Medical Center
Obsessive-Compulsive Disorder
Immersive Virtual Reality & Obsessive Compulsive Disorder
Immersive VR (IVR) is based on the generation and projection of images from different perspectives. Obsessive Compulsive Disorder (OCD) is considered one of the 5 most common mental disorders and one of the 20 most disabling…
- Trial name
- NCT05841017
- Testing
- Psychotherapy with Immersive Virtual Reality support.
- Where
- Spain
- Volunteers
- 98 people
- Sponsor
- Consorci Hospitalari de Vic
Obsessive-Compulsive Disorder
Neurocircuitry of Obsessive-Compulsive Disorder: Modulation by Transcranial Magnetic Stimulation
The purpose of this study is to test the effects of non-invasive neuromodulation, transcranial magnetic stimulation on brain function in individuals with obsessive-compulsive disorder (OCD).
- Trial name
- NCT02704117
- Testing
- Transcranial Magentic Stimulation
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
Obsessive-Compulsive Disorder, Microbiota
Microbiome in Obsessive-compulsive Disorder
Background: Humans live in symbiosis with microbes and their implication for health and disease is evident. The importance of microbiome-gut-brain axis in psychiatric disorders is an area of increasing research interest.
- Trial name
- MIO (NCT03638791)
- Testing
- Exposure and response inhibition
- Where
- Sweden
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Obsessive-Compulsive Disorder, Trichotillomania (Hair-Pulling Disorder)
Epidiolex in Obsessive Compulsive Disorder and Related Disorders
The primary objective of the proposed study is to evaluate the safety and efficacy of Epidiolex (cannabidiol) in adults with obsessive compulsive and related disorders (OCRDs).
- Conditions
- Obsessive-Compulsive Disorder, Trichotillomania (Hair-Pulling Disorder), Tourette Syndrome, Hoarding Disorder
- Trial name
- NCT04978428
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Chicago
Obsessive Compulsive Disorder
Precision Analytic Research Methods in OCD
Psychiatric disorders characterized by compulsivity, such as obsessive-compulsive disorder (OCD), result in considerable functional impairment and many individuals do not respond to gold-standard treatments.
- Trial name
- NCT07011901
- Testing
- Exposure and Response Prevention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Obsessive Compulsive Disorder
Examining the Usage of Dopamine Blockers in OCD Patients
We examine the usage of Dopamine blockers in OCD patients. We want to examine their frequency of usage, compare the course of the disease between those who receive and those who do not receive Dopamine blockers, and efficacy of…
- Trial name
- NCT00496925
- Where
- Israel
- Volunteers
- 63 people
- Sponsor
- Sheba Medical Center
Obsessive-Compulsive Disorder
2/2 D-Cycloserine Augmentation of CBT for Pediatric OCD
The purpose of this study is to find out if D-Cycloserine (DCS), taken at the same time as a child gets cognitive behavioral therapy (CBT) can help children with pediatric obsessive-compulsive disorder.
- Trial name
- NCT01404208
- Testing
- D-Cycloserine
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- Massachusetts General Hospital
Obsessive Compulsive Disorder (OCD)
iCBT for Adolescents Obsessive-compulsive Dissorder
The goal of the study is to assess the feasibility, acceptability, and potential effects of therapist-guided internet-delivered cognitive-behavior therapy (iCBT) for adolescent obsessive-compulsive disorder, using a recently…
- Trial name
- NCT07469358
- Testing
- Behavioral: icbt.
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Hospital Clinic of Barcelona
Obsessive-Compulsive Disorder, Psychiatric Disorder
Ketamine in OCD: Efficacy and Effects on Stress and Cognition
The main goal of this trial is to demonstrate therapeutic efficacy of low dose ketamine in patients with OCD. We expect that ketamine will alleviate symptoms in the hours following application, but also - if effective - that the…
- Trial name
- KET-OCD (NCT05577585)
- Testing
- Ketamine 50 MG/ML Blinded, Midazolam, Ketamine 50 MG/ML Open Label
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Obsessive-Compulsive Disorder
iTBS-DCS in Obsessive Compulsive Disorder
Obsessive Compulsive Disorder (OCD)is a common and debilitating illness. For an unacceptable proportion of patients, depressive symptoms remain impairing despite multiple treatments.
- Trial name
- NCT05177601
- Testing
- iTBS repetitive Transcranial Magnetic Stimulation (rTMS), D-cycloserine
- Where
- Canada
- Volunteers
- 81 people
- Sponsor
- University of Calgary