Clinical trials: Ocular Anesthesia
Ophthalmic Surgery, Parabulbar Block
Anaesthesia for Ophthalmic Surgery: How "Retro" is the Peribulbar Block?
Ophthalmic surgery on the posterior section of the eye can either be performed under general anaesthesia or under local aneasthesia. The local anaesthesia is performed by injecting local anaesthetics behind the eye.
- Trial name
- NCT01258959
- Testing
- Ultrasound detection of local anesthetics spread
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Sunnybrook Health Sciences Centre
Anesthesia, Local, Office Hysteroscopy
Intrauterine Anesthesia in Operative, Awake, Office Hysteroscopy. A Randomized Double-blind Placebo-controlled Trial
Objective: to evaluate intrauterine lidocaine infusion effectiveness in reducing pain associated with operative, awake office hysteroscopy Methods: A total of 100 patients will be randomized for this study The control group…
- Trial name
- NCT05610371
- Testing
- Lidocaine, Saline
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Assuta Ashdod Hospital
Anesthesia-induced Negative Hemodynamic Effects
Atropine-effect During Propofol/Remifentanil Induction
Remifentanil is a widely used potent intravenous opioid with the advantage of having a short time of action. Compared to other opiates however remifentanil generates more intense hemodynamic side-effects.
- Trial name
- NCT01871922
- Testing
- Atropine
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- University Medical Center Groningen
Cataract, Vitreous Disorder
Comparison of Two Surgical Sequences "Cataract Surgery Then Vitrectomy" Versus "Vitrectomy Then Cataract Surgery" Under Local-regional Anesthesia
Cataracts and vitreo-retinal conditions are frequently associated and can lead to a combined surgery to treat both diseases at the same time.
- Trial name
- VICAR (NCT05583331)
- Testing
- Cataract surgery, Vitrectomy
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Elsan
Intraocular Pressure, Anesthesia
An Observational Study of the Use of Chloral Hydrate for Ophthalmic Procedures in Children
The study involves a prospective evaluation of chloral hydrate sedation for the measurement of intraocular pressure in children ages one month to five years of age.
- Trial name
- NCT02985567
- Testing
- Intraocular pressure evaluation
- Where
- Saudi Arabia
- Volunteers
- 324 people
- Sponsor
- Johns Hopkins University
Intubation; Difficult, Failed or Difficult Intubation
Combined Technique for Difficult Intubation
A difficult tracheal intubation can be a problem, even if one has taken all precautions. A possible solution can be using a videolaryngoscope in conjunct with the Bonfils® intubation scope.
- Conditions
- Intubation; Difficult, Failed or Difficult Intubation, Failed or Difficult Intubation, Initial Encounter, Anesthesia Intubation Complication
- Trial name
- NCT01691703
- Testing
- Videolaryngoscope and Bonfils
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Psychological Stress, Anesthesia
RELIEF OF PSYCHOEMOTIONAL STRESS USING XENON SEDATION
The goal of this clinical trial is to propose for implementation and evaluate the effectiveness of xenon sedation for the relief of psychoemotional stress disorder before the operation of refractive laser vision correction…
- Conditions
- Psychological Stress, Anesthesia, Anxiety, Xenon
- Trial name
- NCT06080100
- Testing
- Xenon, premedication hydroxyzine 25 mg
- Where
- Russia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- The S.N. Fyodorov Eye Microsurgery State Institution
Antiseptic, Anesthesia, Local
The Effects of Low Viscosity Chloroprocaine Ophthalmic Gel 3% on the Bactericidal Action of Povidone-Iodine
To evaluate if Iheezo's (chloroprocaine 3%) gel vehicle acts as a barrier on the ocular surface, potentially blocking the bactericidal action of povidone-iodine.
- Trial name
- NCT05934253
- Testing
- Chloroprocaine ophthalmic gel 3%
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Harrow Inc
Pain
Evaluation of Vitrase as an Adjuvant to Increase Absorption and Dispersion of Other Injected Anesthetics
The purpose of this study is to evaluate Vitrase as an adjuvant to increase absorption and dispersion of other injected anesthetics
- Trial name
- NCT00198549
- Testing
- Vitrase (ovine hyaluronidase) Lyophilized
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Bausch & Lomb Incorporated
Urological Manifestations, Anesthesia
Optic Nerve Sheath Diameter in Urologic Surgery
The investigators aimed to determine intracranial pressure changes during spinal and general anesthesia by using optic nerve sheath diameter and near infrared spectrometer in urologic surgery patients in lithotomy position.
- Trial name
- NCT05846555
- Testing
- urologic surgery
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Airway Complication of Anesthesia
A Comparison of Video Laryngoscopes and the Direct Laryngoscope in Simulated Normal and Difficult Infant Airway.
In Pediatric both manikin and human studies have suggested that the video laryngoscopy is equally suitable to facilitate intubation compared to the direct laryngoscopy.
- Trial name
- Kivi (NCT03230422)
- Testing
- normal airway, difficult airway
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Johannes Gutenberg University Mainz
Retinoblastoma, Neurocognitive Dysfunction
Cognitive Functioning and Health Related Quality of Life in Retinoblastoma Survivors
A retrospective crosssectional observational study of the effects of oncological treatment and frequent general anesthesia on neuropsychological development, psychosocial functioning (in terms of anxiety, depression, peer…
- Conditions
- Retinoblastoma, Neurocognitive Dysfunction, Health-Related Behavior
- Trial name
- RbNeuroQoL (NCT06227962)
- Testing
- Neuropsychological assesment, Psychosocial functioning and quality of life (questionnaires), Parental psychosocial functioning (questionnaires)
- Where
- Netherlands
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Amsterdam University Medical Center
Intra Ocular Hypertension
The Effect of Two Different Artificial Respiration Methods on the Intraocular Pressure During Surgery Under General Anesthesia
The purpose of this study is to examine whether the intraocular pressure of operated people under general anesthesia is affected by the artificial respiration method.
- Trial name
- NCT01567761
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Visual Acuity
An Investigation of the Impact of Localized Topical Anesthesia of the Ocular Surface on End-of-day Contact Lens Discomfort
This is a controlled, randomized, subject-masked, 3x3 crossover, non-dispensing, contralateral study. Twenty subjects will be recruited based on their scores (with their habitual lenses) from the Contact Lens Dry Eye…
- Trial name
- NCT03733899
- Testing
- Local Anesthesia
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Strabismus
Peribulbar Block for Prevention of Oculocardiac Reflex
Strabismus is a common ophthalmic problem in Egypt that usually requires surgical correction. This surgery primarily aims to improve alignment of visual axis but may be required only for cosmetic reasons.
- Trial name
- NCT04549844
- Testing
- Bupivacaine
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Fayoum University Hospital
Seeing the Benefits of Using 4 Channel EEG During the DISE Procedure With Sedation
Evaluation of Anesthesia Depth Using 4-channel EEG in Patients Undergoing Drug-induced Sleep Endoscopy (DISE) With Two Different Sedation Methods.
You will undergo a drug-induced sleep endoscopy procedure. The drugs we use to create routine sedation will be used as medication.
- Trial name
- NCT06511128
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ankara City Hospital Bilkent
Intracranial Hypertension, Endotracheal Intubation
Lidocaine, Dexmedetomidine, Esmolol and Magnesium Effect on Optic Nerve Sheath Diameter After Laryngoscopy
This clinical trial aims to compare the effects of lidocaine, dexmedetomidine, esmolol, and magnesium on optic nerve sheath diameter and hemodynamic response to laryngoscopy.
- Conditions
- Intracranial Hypertension, Endotracheal Intubation, Optic Nerve Sheath Diameter, General Anesthesia
- Trial name
- NCT06254534
- Testing
- optic nerve ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Haseki Training and Research Hospital
Total Knee Replacement, Optic Nerve Sheath Diameter Measurement
The Effect of Epidural Anesthesia on Optic Nerve Sheath Diameter Measurements in Total Knee Prosthesis Surgery
This study investigates the effects of epidural anesthesia on intracranial pressure (ICP) by using ultrasonographic optic nerve sheath diameter (ONSD) measurements as a non-invasive indicator.
- Conditions
- Total Knee Replacement, Optic Nerve Sheath Diameter Measurement, Intracranial Pressure Change
- Trial name
- NCT07458321
- Testing
- Bupivacaine %0.25 (isobaric), Bupivacaine %0.5 (hyperbaric)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa City Hospital
Deafness, Blindness
Workshops for Veterans With Vision and Hearing Loss
This is a pilot study of workshops to help Veterans with both vision and hearing loss live a happier, fuller and less stressful life. The results will be used to guide the development of a large scale clinical trial.
- Trial name
- DSLW (NCT01109576)
- Testing
- DSL Workshop
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- US Department of Veterans Affairs
Intracranial Pressure Change, Optic Nerve Diameter
VIMA vs TIVA and ONSD in Laparoscopic Cholecystectomy
This study compared two commonly used general anesthesia techniques in adults undergoing elective laparoscopic gallbladder surgery.
- Trial name
- NCT07786740
- Testing
- Propofol (Astra-Zeneca), Remifentanil, Sevofluorane
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bagcilar Training and Research Hospital