Clinical trials: Ocular Diseases
Childhood Absence Epilepsy, Absence Seizures
Assessing Comorbidities in Epilepsy Using Eye Movement Recordings
This study wants to make it easier to find kids with a type of epilepsy called childhood absence epilepsy (CAE) who might have problems with ongoing seizures and thinking.
- Conditions
- Childhood Absence Epilepsy, Absence Seizures, Epilepsy Comorbidities
- Trial name
- ACER (NCT06310772)
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eysz, Inc.
Dry Eye
Subjective and Objective Performance of Systane Complete Multi-Dose PF Versus Walgreen's Lubricant Balance
Single site, prospective, double-masked, randomized-controlled, two-arm study of the dry eye symptoms as well as corneal and conjunctival staining in subjects using 2 different eyedrops.
- Trial name
- NCT06219577
- Testing
- Systane Complete Multi-Dose PF, Walgreen's Lubricant Balance
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Scripps Poway Eyecare and Optometry
Alopecia, Breast Cancer
Bimatoprost Ophthalmic Solution in Increasing Eyebrow and Eyelash Growth in Patients Who Have Undergone Chemotherapy for Breast Cancer and in Healthy Participants
RATIONALE: Bimatoprost ophthalmic solution may help increase eyebrow and eyelash growth in patients who have undergone chemotherapy.
- Trial name
- NCT00999557
- Testing
- bimatoprost ophthalmic solution
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Jonsson Comprehensive Cancer Center
Glaucoma
Safety and Tolerability of the Preservative-free Ophthalmic Solution PRO-122 Compared With Krytantek Ofteno®
Therapeutic indication: Ocular hypotensive Use: Primary open-angle glaucoma and ocular hypertension. Objectives: To evaluate the safety and tolerability of the preservative-free formulation PRO-122 manufactured by Sophia…
- Trial name
- PRO-122/I (NCT03966365)
- Testing
- PRO-122, Krytantek Ofteno®
- Where
- Mexico
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Laboratorios Sophia S.A de C.V.
Amblyopia
Study of Binocular Computer Activities for Treatment of Amblyopia
The purpose of the study is to compare the effectiveness of 1 hour/day of binocular game play 7 days per week with 2 hours/day patching 7 days per week in children 5 to <17
- Trial name
- ATS18 (NCT02200211)
- Testing
- iPad®, Patching 2 hours per day, 7 days per week
- Where
- 2 sites in United States
- Volunteers
- 485 people
- Sponsor
- Jaeb Center for Health Research
Uveitis
Simvastatin in Uveitis
The study evaluates anti-inflammatory effects and safety of simvastatin in non-infectious uveitis.
- Trial name
- NCT04183387
- Testing
- Simvastatin 40mg
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- Federal State Budgetary Scientific Institution, Research Institute of Fundamental and Clinical Immunology
Eye Diseases
Multimodal Equipment for Teleophthalmology Assessment (META)
We have developed a Multimodal Equipment for Teleophthalmology Assessment (META) device. This novel device is compact, portable and suitable for packaging and express delivery.
- Trial name
- NCT05565547
- Testing
- META, Commercial devices
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Glaucoma, Open-Angle, Failing Bleb Following Trabeculectomy
Treatment of Failing Blebs With Ranibizumab
This study was designed to evaluate the efficacy and safety in the use of Ranibizumab, an effective vascular endothelial growth factor (VGEF) inhibitor, in treating patients with a failing bleb, characterized by increased…
- Trial name
- NCT00570726
- Testing
- Ranibizumab (Lucentis)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- The New York Eye & Ear Infirmary
Demyelinating Disorders, Multiple Sclerosis
Induction Therapy With a Single High Dose Bolus of Intravenous Methotrexate With Leucovorin Rescue, Prior to Initiation of AVONEX® Treatment, in Patients Presenting With a First Acute Demyelinating Event.
The participant will receive weekly intramuscular treatment with AVONEX® (interferon beta 1-a) and a one-time high dose intravenous methotrexate with Leucovorin rescue, along with the standard solumedrol treatment before…
- Conditions
- Demyelinating Disorders, Multiple Sclerosis, Optic Neuritis, Myelitis
- Trial name
- NCT00037115
- Testing
- interferon beta 1a, methotrexate, methylprednisolone
- Where
- United States
- Sponsor
- MidAmerica Neuroscience Research Foundation at Rowe Neurology Institute
Age-related Macular Degeneration
Efficacy and Safety of Two Different Brolucizumab 6 mg Dosing Regimens in Neovascular Age-related Macular Degeneration
The purpose of this study was to evaluate the efficacy and safety of two different brolucizumab 6 mg dosing regimens in patients with visual impairment due to age-related macular degeneration (AMD) who have previously received…
- Trial name
- FALCON (NCT04679935)
- Testing
- Brolucizumab
- Where
- 19 sites in Germany, Switzerland
- Volunteers
- 52 people
- Sponsor
- Novartis Pharmaceuticals
Astigmatism
Evaluation of Orientation and Visual Acuity of Four Toric Soft Contact Lenses When Head is Tilted at 90 Degrees
The purpose of this study is to determine the relative performance of a new toric soft contact lens against three toric contact lens currently available in market, specifically with orientation and visual acuity when head is…
- Trial name
- NCT00583908
- Testing
- senofilcon A, balafilcon A toric, lotrafilcon B toric
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataracts
PROOF-OF-CONCEPT STUDY FOR NEW INTRAOCULAR LENS, MODEL C0002
Prospective, two-arm, randomized, bilateral, subject/evaluator-masked clinical study to evaluate the distance visual acuity, peripheral refractive error and functional vision of the EPV IOL compared to a standard monofocal…
- Trial name
- NCT05531292
- Testing
- Model C0002, Model ZCB00/DCB00
- Where
- 2 sites in France
- Volunteers
- 106 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Myopia
Eye Exercise, Transcutaneous Electrical Nerve Stimulation on Prevention of Myopia Progression
In Taiwan, the increasing prevalence of myopia shows a decline with age. Myopia has become a serious ocular problem in children because high myopia may lead to retinal damage, cataract and glaucoma.
- Trial name
- NCT04017234
- Testing
- frequency following response, eye exercise, and transcutaneous
- Where
- Taiwan
- Volunteers
- 27 people
- Sponsor
- China Medical University Hospital
Rhinitis, Allergic, Seasonal
Nasal Ocular Reflexes Contribute to Eye Symptoms
Eye symptoms of tearing, redness and itching frequently occur in patients with allergic rhinitis or hayfever. The purpose of this trial is to study whether placing an allergen (a substance that causes allergies) directly in your…
- Trial name
- NCT00117832
- Testing
- Azelastine nasal spray
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Graves' Ophthalmopathy
Thyroid-Associated Ophthalmopathy Subtypes and Orbital Antibodies
The purpose of this study is to determine whether radioactive iodine, as compared to anti-thyroid medications, is a risk factor for the development or progression of thyroid-associated ophthalmopathy in patients with…
- Trial name
- NCT00430547
- Testing
- Carbimazole, radio-active iodine (I131)
- Where
- Australia
- Volunteers
- 60 people
- Sponsor
- Barwon Health
Uveitis
Phase 2b Pivotal Study of Izokibep in Non-infectious, Intermediate-, Posterior- or Pan-uveitis
Izokibep is a small protein molecule that acts as a selective, potent inhibitor of interleukin-17A, to which it binds with high affinity.
- Trial name
- NCT05384249
- Testing
- Izokibep
- Where
- 69 sites in United States, Austria and 5 more
- Volunteers
- 96 people
- Sponsor
- ACELYRIN Inc.
Diabetic Macular Edema, Cataract
Anti-VEGF Intravitreous Injections for Diabetic Macular Edema in Patients Undergoing Cataract Surgery
The investigators aim to evaluate how different timing of anti-VEGF intravitreous injections affect visual acuity (BCVA) in patients with diabetic macular edema who are undergoing cataract surgery; and to evaluate how different…
- Trial name
- Anti-VEGF (NCT04063358)
- Testing
- Lucentis
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Second Military Medical University
Neuromyelitis Optica Spectrum Disorders, Pain
Efficacy of Electroacupuncture in NMOSD Patients With Pain: Study Protocol
Abstract Background Neuropathic pain is a common complication in neuromyelitis optica spectrum disorder (NMOSD), which seriously affects the quality of life of NMOSD patients, with no satisfactory treatment.
- Trial name
- NCT05871658
- Testing
- electroacupuncture
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Yuanqi Zhao,MD
Glaucoma
Effects of Balance Training in Individuals With Glaucoma
Glaucoma is a chronic progressive eye disease characterized by visual field loss, which may adversely affect postural control, functional mobility, and increase the risk and fear of falling.
- Trial name
- NCT07910955
- Testing
- Balance Training Program
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Myopia, Visual Fatigue
Discussion on the Effectiveness of Tea on Blood Pressure, Body Composition and Vision Problems in College Students
Background: Tea is a universal beverage and one of the most popular drinks around the world. Some cell and animal experiments have pointed out that drinking tea may be related to hypotension, body composition and vision problems…
- Conditions
- Myopia, Visual Fatigue, Blood Pressure, Body Composition
- Trial name
- NCT06570226
- Testing
- hibiscus tea
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hungkuang University
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