Clinical trials: Ocular Diseases
Uveitis
RChildUV:Study on Non-infectious Chronic Uveitis in Pediatric Age
Uveitis is an inflammatory disease of the uvea, one of the highly vascularized fundamental structures of the eye. It is a rare condition in children, with an incidence in the pediatric population ranging from 2% to 14% of all…
- Trial name
- NCT06273748
- Where
- 19 sites in United States, Belgium and 3 more
- Volunteers
- 290 people
- Sponsor
- Meyer Children's Hospital IRCCS
Glaucoma
Mirtogenol and Bimatoprost on IOP in Hispanics With Open-Angle Glaucoma
A prospective, parallel-group, double-blind, randomized placebo-controlled clinical study will be conducted with an estimated 72 participants.
- Trial name
- NCT04380025
- Testing
- Experimental: Oral Mirtogenol
- Where
- Puerto Rico
- Volunteers
- 72 people
- Sponsor
- University of Puerto Rico
Cataract
Evaluation of Therapeutic Strategies in Pediatric Cataract Surgery
The purpose of this observational study is to assess the therapeutic strategies in the treatment of pediatric cataracts.
- Trial name
- EP3C (NCT02253017)
- Testing
- Children operated on for cataract
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Glaucoma Eye
Assessment of the Occuity PM1 Pachymeter
To determine whether the Occuity PM1 device is non-inferior in measuring central corneal thickness when compared to ultrasound pachymetry, the Lenstar and the Pentacam.
- Trial name
- NCT05895617
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Occuity Limited
Dry Eye Disease
Evaluating the Safety, Tolerability, and Efficacy of GRF312 5% in Participants With Dry Eye Disease (DED).
This is a Phase 2, multi-site, double-masked, randomized, vehicle-controlled, study designed to evaluate the safety, tolerability, and efficacy in adult participants with DED.
- Trial name
- NCT07264517
- Testing
- GRF312 5%
- Where
- 10 sites in United States
- Volunteers
- 103 people
- Sponsor
- Instituto Grifols, S.A.
Cataract
Randomized Trial of Aspirin and Cataracts in U.S. Physicians
To determine whether 325 mg of aspirin taken on -alternate days reduces the risk of developing cataract among male U.S. physicians who were aged 40 to 84 in 1982.
- Trial name
- NCT00000157
- Testing
- Aspirin
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Diabetic Retinopathy
Pivotal Trial to Assess the Clinical Performance of Ophthal-360 for the Detection of Diabetic Retinopathy
Multicenter, prospective, study to assess the performance of the Ophthal-360 platform in the diagnosis of more-than-mild Diabetic Retinopathy (mtmDR) in diabetic patients with no previous diagnosis of DR.
- Trial name
- NCT05806957
- Testing
- Fundus Photography
- Volunteers
- 500 people
- Sponsor
- Ophthalytics, Inc.
Ocular Pain, Dry Eye
Study to Evaluate the Ocular Tolerance of SYL1001 in Healthy Volunteers
The purpose of this study is to determine whether SYL1001 is safe for the prevention and treatment of ocular pain and dry eye syndrome.
- Trial name
- NCT01438281
- Testing
- SYL1001
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sylentis, S.A.
Myopia, Astigmatism
Daily Disposable Toric Comparative Trial in Europe
The purpose of this study is to investigate the subjective and objective performance of two daily disposable lenses for wearers with astigmatism.
- Trial name
- NCT01070381
- Testing
- nelfilcon A contact lens, ocufilcon D contact lens
- Volunteers
- 220 people
- Sponsor
- CIBA VISION
Retinopathy of Prematurity
Peripheral Avascular Retina in Retinopathy of Prematurity
Retinopathy of prematurity (ROP) is a widely known retinal vascular disorder in preterm infants and a leading cause of visual disability or blindness in children.
- Trial name
- NCT06044181
- Testing
- Diode laser photocoagulation.
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Assiut University
Vision, Low
Mobile Electronic Devices for Visual Impairment
Mobile electronic devices (MED) including, smartphones and tablets, offer a new type of assistive technology for visually-impaired people (VIP).
- Trial name
- MED4VI (NCT03560765)
- Testing
- MED, Buddy
- Where
- 2 sites in United Kingdom
- Volunteers
- 25 people
- Sponsor
- University of Manchester
Glaucoma, Intraocular Pressure
Comparing Rates of Glaucoma in Professional Wind Versus Non-Wind Instrument Players
The purpose of the present study is to compare rates of glaucomatous optic neuropathy in professional wind versus non-wind instrument players in the Philadelphia Orchestra.
- Conditions
- Glaucoma, Intraocular Pressure, Optic Neuropathy
- Trial name
- NCT02612571
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Wills Eye
Idiopathic Macular Hole, Macular Hole
Intraocular Gas Tamponade for Treatment of Large Idiopathic Macular Holes
The goal of this clinical trial is to evaluate the visual and anatomical outcomes of large (410-1000 μm) full-thickness macular holes repair surgery using perfluoropropane (15% C3F8), sulfur hexafluoride (20% SF6) gas tamponade.
- Conditions
- Idiopathic Macular Hole, Macular Hole, Macular Holes, Full Thickness Macular Hole
- Trial name
- NCT06927544
- Testing
- Pars plana vitrectomy
- Where
- Ukraine
- Volunteers
- 100 people
- Sponsor
- The Filatov Institute of Eye Diseases and Tissue Therapy
Cataract
Posterior Assisted Levitation of Dropped Nucleus
Dropping of nucleus is a common complication during cataract extraction by phacoemulsification. The investigators describe a new technique to retrieve the dropped nucleus by using an instrument called Pars Plana Levitator…
- Trial name
- PAL (NCT00974844)
- Where
- Pakistan
- Volunteers
- 14 people
- Sponsor
- Dow University of Health Sciences
Behçet
Role of Femoral Vein Wall Thickness and Inflammatory Markers in Patients With Behcet Disease
Evaluation of femoral vein wall thickness and inflammatory indices in patients with Behcet disease and assessment of their relation to the disease activity and related some clinical manifestations
- Trial name
- NCT06721234
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Cataracts, Corneal Edema
Study of Difluprednate vs. Prednisolone Acetate on Visual Acuity, and Corneal Edema Following Cataract Surgery.
The purpose of this clinical research study is to investigate the efficacy of predosing patients undergoing cataract surgery with the potent corticosteroid difluprednate ophthalmic emulsion 0.05% compared to prednisolone acetate…
- Conditions
- Cataracts, Corneal Edema, Retinal Structural Change, Deposit and Degeneration, Visual Acuity Reduced Transiently
- Trial name
- NCT01244334
- Testing
- Difluprednate ophthalmic emulsion 0.05%, Prednisolone acetate 1%
- Where
- 3 sites in United States
- Volunteers
- 52 people
- Sponsor
- Edward J. Holland
Myopia
Myopia Control With Simultaneous Vision Approach
To determine if the 'Defocus Incorporated Soft Contact' (DISC) lens slows myopia progression in Hong Kong schoolchildren using simultaneous vision approach.
- Trial name
- NCT00919334
- Testing
- Defocus Incorporated Soft Contact (DISC) lens
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Uveitis
Study to Evaluate the Long Term Use of Treatment With AIN457 for Uveitis
This study will provide patients who have completed the AIN457 Phase II and Phase III clinical trials in non-infectious uveitis continued access to treatment with AIN457 while collecting safety data and information on long term…
- Trial name
- SUPPORT (NCT01327664)
- Testing
- AIN457
- Sponsor
- Novartis Pharmaceuticals
Intracranial Hypertension
Comparison of the Effects of Deep and Moderate Neuromuscular Blockade on Optic Nerve Sheath Diameter
Increased intracranial pressure (IICP) is a common problem in traumatic brain injuries and many medical diseases. Early recognition of IICP can save lives.
- Trial name
- MBLONDE (NCT04211064)
- Testing
- Ultrasonographic measurement of optic nerve sheath diameter, Deep neuromuscular block, Moderate neuromuscular block
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Oculomotor Nerve Palsy, Trochlear Nerve Palsy
A Retrospective Study of the Effects of Ocular Acupuncture on Ocular Motor Nerve Palsy
This retrospective observational study is designed to assess the response to treatment with ocular acupuncture and its relative factors, in terms of diplopia status, ocular motility differences, and clinical features, in ocular…
- Conditions
- Oculomotor Nerve Palsy, Trochlear Nerve Palsy, Abducens Nerve Paralysis
- Trial name
- NCT03461809
- Testing
- Ocular acupuncture
- Volunteers
- 900 people
- Sponsor
- First Affiliated Hospital of Harbin Medical University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.