Clinical trials: Ocular Hypertension
Glaucoma
Comparing NGENUITY vs Conventional Microscope in a New Hydrus User
To compare the potential efficiency and educational value of using NGENUITY (3D camera system, FDA approved for this indication) vs the conventional microscope for Hydrus microstent placement by new users.
- Trial name
- NCT05529966
- Testing
- NGENUITY, Conventional microscope
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Stanford University
Glaucoma, Open-Angle
A Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System
The purpose of this study is to evaluate the long-term safety and effectiveness of the OMNI® Surgical System in subjects who were treated under protocol #06213
- Trial name
- NCT05044793
- Testing
- OMNI® Surgical System
- Where
- 4 sites in United States
- Volunteers
- 70 people
- Sponsor
- Sight Sciences, Inc.
Glaucoma, Open-Angle, Ocular Hypertension
To Compare the Efficacy and Safety of Perrigo's Product to an FDA Approved Product for the Treatment of Glaucoma or Ocular Hypertension in Both Eyes
To compare the efficacy and safety of Perrigo's product to an FDA approved product in the treatment of Primary Open Angle Glaucoma or Ocular Hypertension in Both Eyes.
- Trial name
- NCT04944290
- Testing
- Brinzolamide/brimonidine ophthalmic suspension, Simbrinza 0.2%/1% Ophthalmic Suspension
- Where
- United States
- Volunteers
- 447 people
- Sponsor
- Padagis LLC
Glaucoma, Ocular Hypertension
Efficacy and Tolerability of Xalatan in Patients
Efficacy data was not collected or analyzed. This study did assess safety and tolerability of Xalatan.
- Trial name
- A6111128 (NCT00950690)
- Testing
- Xalatan 0.005% eye drops
- Where
- 3 sites in Egypt, Saudi Arabia and 1 more
- Volunteers
- 1,289 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Glaucoma, Open Angle, Ocular Hypertension
Patient Satisfaction With Timolol in Subjects With Open-Angle Glaucoma or Ocular Hypertension
This study compares patient symptoms and anterior segment safety in patients treated with timolol hemihydrate, generic timolol gel forming solution or timolol maleate.
- Trial name
- NCT00804648
- Testing
- Timolol Maleate in Sorbate, Timolol hemihydrate, Timolol maleate gel forming solution
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Vistakon Pharmaceuticals
Primary Open Angle Glaucoma, Cataract
Additional Long-Term Follow-up for Subjects Implanted With a CyPass® Micro-Stent
The purpose of this study is to assess long-term (10 years post-CyPass implantation) status of the corneal endothelium in subjects who were implanted with the CyPass Micro-Stent in the COMPASS trial.
- Trial name
- COMPASS XXT (NCT04629521)
- Testing
- CyPass Micro-Stent, Cataract Surgery
- Where
- 12 sites in United States
- Volunteers
- 54 people
- Sponsor
- Alcon Research
Intracranial Pressure Increase
Ocular Screening in Children and Young Adults at Risk for Increased Intracranial Pressure
The purpose of this study is to evaluate the vision and posterior segment of eyes in children and young adults less than 22 years of age with risk, suspicion, or past medical history significant for elevated intracranial pressure…
- Trial name
- ICP (NCT03286426)
- Testing
- Pictor
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Duke University
Primary Open Angle Glaucoma, Ocular Hypertension
Study of LL-BMT1 in Patients With Elevated Intraocular Pressure
This is an open-label, Phase 2a clinical study of LL-BMT1 in patients with primary open-angle glaucoma and ocular hypertension. Study subjects will be treated for 7 days with a single dose of LL-BMT1.
- Trial name
- NCT04747808
- Testing
- LL-BMT1
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- MediPrint Ophthalmics, Inc.
Elevated Intracranial Pressure (ICP)
Optic Nerve Sheath Diameter (ONSD) With the Raised PCO2 and Internal Jugular Venous Occlusion
Monitoring the ICP is the most important aspect of the management of these patients. Recently, transorbital ultrasonography has gained popularity as a noninvasive bedside exam that has been shown to be useful in the diagnosis of…
- Trial name
- NCT02361658
- Testing
- Ultrasonographic of the optic nerve sheath diameter, RespirAct™, Neck collar
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lashmi Venkatraghavan
Glaucoma
Effect of Age on Latanoprost 0.005% in Patients With Glaucoma
Latanoprost is a commonly used treatment for glaucoma. Because of its mechanism of action, it is plausible that the age of a patient using the medication may affect its efficacy and time of onset.
- Trial name
- NCT00224289
- Testing
- Latanoprost 0.005%
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Yale University