Clinical trials: Ocular Hypertension Glaucoma
Glaucoma
Spectralis OCT Repeatability and Reproducibility Study
This single-center, prospective, interventional clinical study is conducted to evaluate the repeatability and reproducibility of structural parameters of the optic nerve head, the peripapillary retinal nerve fiber layer, and the…
- Trial name
- S-2013-1 (NCT02209077)
- Testing
- OCT performed to collect data from the back of the eye
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Heidelberg Engineering GmbH
Glaucoma
The Water Drinking Test in Glaucoma Study
To investigate the correlation and agreement between the intraocular pressure peaks detected during the water drinking test and modified diurnal tension curve in glaucomatous eyes and to analyse whether this is associated with…
- Trial name
- WIGS (NCT05283031)
- Testing
- Modified Diurnal Tension Curve
- Where
- United Kingdom
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Glaucoma
Randomized Controlled Trial on Visual Field Training
Unreliability and visual field variability is a known problem with automated perimetry in both developing and developed country settings.
- Trial name
- NCT01669031
- Testing
- Practice program
- Where
- Chile
- Volunteers
- 200 people
- Sponsor
- Oftalmologia Hospital Sotero del Rio
Retinal Disease, Macular Degeneration
Stem Cell Ophthalmology Treatment Study
This study will evaluate the use of autologous bone marrow derived stem cells (BMSC) for the treatment of retinal and optic nerve damage or disease. http://mdstemcells.com/scots-ii/
- Conditions
- Retinal Disease, Macular Degeneration, Hereditary Retinal Dystrophy, Optic Nerve Disease
- Trial name
- SCOTS (NCT01920867)
- Testing
- RB (Retrobulbar), ST (Subtenon), IV (Intravenous)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- MD Stem Cells
Glaucoma, Open-angle
The Effectiveness of YAG Iridotomy in Preventing Peripheral Anterior Synechia After CLASS in Primary Open Angle Glaucoma
To investigate the effectiveness of YAG laser iridotomy in preventing peripheral anterior synechia after CO2 Laser-Assisted Sclerectomy Surgery and the long-term effect of reducing intraocular pressure
- Trial name
- NCT04912362
- Testing
- YAG iridotomy
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Glaucoma
The Role of Music in Enhancing Attention During Visual Field Exams for Pediatric Glaucoma Patients
The goal of the study is to see if the use of music improves attention during visual field exams for pediatric glaucoma patients.
- Trial name
- NCT06971588
- Testing
- Music intervention
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Johns Hopkins University
Glaucoma
Discriminating Ability of the Cirrus High Definition (HD) Optical Coherence Tomography (OCT) for Glaucoma
The Cirrus HD OCT, a new spectral domain optical coherence tomography, has better resolution than the previous OCT. Reproducibility and discriminating ability of the Cirrus HD OCT for glaucoma detection will be studied.
- Trial name
- NCT00742378
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Glaucoma
The Effectiveness of Ologen® Collagen Matrix in Preventing Intraocular Pressure (IOP) Spikes After Ahmed Glaucoma Valve Surgery (AGV-FP7)
The purpose of this study is to investigate whether placing Ologen over the posterior plate of the Ahmed glaucoma drainage device during initial implantation will allow the formation of a thinner capsule, and decrease the…
- Trial name
- NCT02990143
- Testing
- Ologen
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The New York Eye & Ear Infirmary
Primary Open Angle Glaucoma, Ocular Hypertension
A Randomized, Open-label, Active-controlled, Phase 2a Clinical Trial to Evaluate the Efficacy and Safety of TFC-003 in Patients With Primary Open-angle Glaucoma or Ocular Hypertension
The purpose of this study was to explore the efficacy and safety of the weekly intraocular pressure change of the TFC-003 group and the dorzolamid/timolol combination group in patients with primary open-angle glaucoma or ocular…
- Trial name
- NCT06177678
- Testing
- TFC-003, COSOPT ophthalmic solution
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Kukje Pharma
Glaucoma, Angle-Closure
Clinical Efficacy and Safety of Minimally Invasive Glaucoma Surgery on Primary Angle Closure Glaucoma
To evaluate the clinical efficacy (intraocular pressure reduction , success rate, the number of antiglaucoma medication) and safety of ab interno trabeculectomy (AIT) with Trabectome in Chinese PACG .
- Trial name
- NCT02964676
- Testing
- ab interno trabeculectomy with Trabectome, trabeculectomy
- Volunteers
- 246 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Open-Angle Glaucoma, Ocular Hypertension
Three Month Efficacy/Safety Study With a 3-Month Safety Extension of Brinzolamide 1%/Brimonidine 0.2% vs. Brinzolamide 1% or Brimonidine 0.2%
The purpose of this study was to evaluate the safety and efficacy of a new ophthalmic suspension (Brinz/Brim) in lowering intraocular pressure (IOP) relative to its individual active components in subjects with open-angle…
- Trial name
- NCT01297920
- Testing
- Brinzolamide 1%/brimonidine tartrate 0.2% ophthalmic suspension, Brinzolamide ophthalmic suspension, 1%, Brimonidine tartrate ophthalmic solution, 0.2%
- Volunteers
- 1,062 people
- Sponsor
- Alcon Research
Primary Open Angle Glaucoma, Ocular Hypertension
ATS907 Ph2a Open-Label Dose-ranging Safety and Tolerability in Primary Open Angle Glaucoma (POAG) and Ocular Hypertension (OHT) Subjects
This single-site, dose-escalation study will evaluate safety and tolerability of increasing concentrations of ATS907 in 12 subjects with Primary Open Angle Glaucoma and/or Ocular Hypertension
- Trial name
- NCT01668524
- Testing
- ATS907
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Altheos, Inc.
Glaucoma, Open-Angle
Safety and Effects of Brimonidine Intravitreal Implant in Patients With Glaucomatous Optic Neuropathy
A multicenter, randomized, patient-masked, sham-controlled evaluation of the safety and effects on visual function of brimonidine intravitreal implant in patients with glaucomatous optic neuropathy.
- Trial name
- NCT00693485
- Testing
- 400 ug Brimonidine Implant, 200 ug Brimonidine Implant
- Where
- 2 sites in United States, Israel
- Volunteers
- 70 people
- Sponsor
- Allergan
Glaucoma, Angle-Closure
Laser Peripheral Iridotomy Plus Laser Peripheral Iridoplasty for Primary Angle Closure
This is a 10-centre randomized controlled clinical trial to explore whether laser peripheral iridoplasty (LPIP) plus laser peripheral iridotomy (LPI) is more effective than single LPI to control the progression of primary angle…
- Trial name
- NCT02613013
- Testing
- neodymium:yttrium-aluminum- garnet laser, frequency-doubled Q-switched neodymium:yttrium-aluminum-garnet 532-nm laser, Pilocarpine
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Sun Yat-sen University
Glaucoma
Circadian Ocular Perfusion Pressure and Ocular Blood Flow
The purpose of this study was to compare the short term effects of two intraocular pressure (IOP) lowering medications on ocular perfusion pressure (OPP), ocular blood flow, intraocular pressure, and blood pressure in patients…
- Trial name
- NCT00800540
- Testing
- Brinzolamide 10 mg/ml/Timolol 5 mg/ml eye drops suspension, Brimonidine 20 mg/ml/Timolol 5 mg/ml eye drops solution
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Alcon Research
Open-Angle Glaucoma, Ocular Hypertension
SIMBRINZA® Suspension BID as an Adjunctive to Prostaglandin Analogue (PGA)
The purpose of this study is to evaluate the additive intraocular pressure (IOP) lowering effect of brinzolamide 1%/brimonidine 0.2% (dosed twice per day (BID)) when added to a prostaglandin analogue (PGA) in subjects with…
- Trial name
- NCT02419508
- Testing
- Brinzolamide 1%/brimonidine 0.2% tartrate ophthalmic suspension, Brinz/brim vehicle, Prostaglandin analogue
- Where
- United States
- Volunteers
- 290 people
- Sponsor
- Alcon Research
Glaucoma
Change in IOP Fluctuation After DSLT
This is a prospective, single-center, single-arm, observational study designed to evaluate the change in diurnal intraocular pressure (IOP) fluctuation following Direct Selective Laser Trabeculoplasty (DSLT) in patients with…
- Trial name
- NCT07428668
- Testing
- Voyager DSLT
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Ophthalmology Associates, Fort Worth
Glaucoma
ICare Self-tonometry - A Head-to-head Comparison to the Gold Standard Goldmann Tonometer
The purpose of this study is to compare glaucoma patients' own I Care measurements by the standard Goldmann applanation tonometer intraocular pressure (IOP) measurements.
- Trial name
- NCT01733550
- Testing
- Home iCare (study nurse), goldmann applanation tonometry, home iCare (by patient)
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Glaucoma
Morphometric Markers of the Effectiveness of Micropulse Cyclophotocoagulation
This prospective study aims to evaluate morphometric markers of treatment response following micropulse transscleral cyclophotocoagulation (MP-CPC) in patients with glaucoma.
- Trial name
- MMEMC (NCT07592923)
- Testing
- MicroPulse transscleral cyclophotocoagulation, Conventional transscleral cyclophotocoagulation
- Where
- Kazakhstan
- Volunteers
- 20 people
- Sponsor
- Kazakh Eye Research Institute
Ocular Hypertension
Safety and Efficacy of Liposomal Latanoprost in Ocular Hypertension
Aim: Evaluation of a single subconjunctival injection of liposomal EggPC formulation of latanoprost in treating glaucoma. Hypothesis: The investigators have already evaluated carrier stability, drug partitioning, in vitro drug…
- Trial name
- NCT01987323
- Testing
- Subconjunctival injection of liposomal latanoprost
- Volunteers
- 6 people
- Sponsor
- Singapore Eye Research Institute
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.