Clinical trials: Ocular Microbiome
Sjogren's Syndrome
Sjogren's Mini-Pill Oral and Gut Microbiome Study
The goal of this observational study is to characterize and compare region-specific gastrointestinal, stool, oral, and periodontal microbiomes in adults with Sjögren's disease and healthy controls using ingestible mini-pill…
- Trial name
- NCT07732582
- Testing
- Mini-Pill
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tufts University
Rosacea, Ocular Rosacea
Lipidome and Microbiome Profile of the Eye in Rosacea
The question that the investigators aim to address in this proposal is how the local lipid mediator profiles of ceramides and eicosanoids are altered in cutaneous and ocular rosacea and how antibiotics alter the lipidome.
- Conditions
- Rosacea, Ocular Rosacea, Cutaneous Rosacea
- Trial name
- NCT03655197
- Testing
- Doxycycline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Retinopathy of Prematurity, Microbiome
The Analysis of Association of Retinopathy of Prematurity, Gut Microbiome Profile, and Systemic Inflammation
Study Aims 1. Understanding the gut microbiome profile in very low birth weight infants with or without ROP. The onset and aggravation of ROP and their relationship with gut microbiome will be examined. 2.
- Trial name
- NCT05144282
- Testing
- intravitreal injection of anti VEGF, laser photocoagulation
- Where
- Taiwan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Chalazion
Probiotics for Treatment of Chalazion in Adults
There is growing evidence encouraging probiotics use in several diseases. The aim of the investigator's study is to define the possible beneficial impact of probiotics on adults suffering from chalazia.
- Trial name
- NCT04342507
- Testing
- conservative treatment, probiotics
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Molise
Antibiotic Resistance, Ocular Surface Microbiome
Antibiotic Resistance In Eye Surgeries
In this study, the investigators seek to determine the effect of antibiotic use post-surgery on antimicrobial resistance. The investigators will be studying adults (aged 18 or older) who will undergo eye surgery at University of…
- Conditions
- Antibiotic Resistance, Ocular Surface Microbiome, Gut Resistome
- Trial name
- ARIES (NCT04750655)
- Testing
- Moxifloxacin (Topical)
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- University of California, San Francisco
Infectious Keratitis
Investigation of the Microbiome of the Cornea in Microbial Keratitis
Design: Prospective observational diagnostic study and methods-comparison. Aims: The overall aim of the project is to better define the pathogenic microorganisms in patients with microbial keratitis (MK) through a better…
- Trial name
- STOICA (NCT04030403)
- Where
- United Kingdom
- Volunteers
- 219 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Geographic Atrophy, Age-Related Macular Degeneration
Oral Postbiotics in Patients With Macular Atrophy
A pilot study to evaluate the safety and efficacy of oral therapy with Postbiotics in patients with geographic atrophy secondary to age-related macular degeneration, myopia, or angioid streaks.
- Trial name
- REVERS-GA (NCT05391074)
- Testing
- postbiotics (IGENH35.3A), vitamins (AREDS formulation and recommended daily dose)
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Institut de la Macula y la Retina