Clinical trials: Ocular Surface
Keratoconus
Accuracy of Curvature and Wavefront Aberrations of Posterior Corneal Surface, in Keratoconic and Post-CXL Corneas
Primary objective of this study was to assess the intrasession, intersession and interobserver variability of the Pentacam-derived curvature and zernike coefficients in back surface of normal, keratoconic and crosslinked corneas.
- Trial name
- NCT01527708
- Testing
- Corneal Collagen Cross-linking (CXL)
- Where
- Greece
- Volunteers
- 129 people
- Sponsor
- Democritus University of Thrace
Glaucoma, Open-Angle Glaucoma
Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication Use
The objective of this study is to evaluate whether reduction in topical medication with the injection of a sustained release capsule (Durysta) leads to a reduction in ocular surface inflammation, indicated by levels of caspase-1…
- Conditions
- Glaucoma, Open-Angle Glaucoma, Ocular Hypertension, Glaucoma Suspect
- Trial name
- NCT07217678
- Testing
- Durysta, Bimatoprost Intracameral Implant 10 µg
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Miami
Ocular Surface Disease, Neurotrophic Keratopathy Stage 1
Effect of Acoltremon Ophthalmic Solution 0.003% on Signs and Symptoms of Ocular Surface Disease in Stage I Neurotrophic Keratopathy Patients With Tear Deficiency
STUDY OBJECTIVE To assess if acoltremon 0.003% improves tear production in patients with Stage 1 Neurotrophic Keratopathy.
- Trial name
- NCT07502378
- Testing
- Patients will receive topical Acoltremon 0.003% ophthalmic solution BID in both eyes over an 8 week period., Alternative would be patient exiting the trial and starting on tears or other standard of care.
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of South Florida
Dry Eye
Objective Evaluation of Ocular Surface Lubricants in Two Environments
This study will evaluate ocular surface lubricants in subjects with dry eye syndrome.
- Trial name
- NCT01375582
- Testing
- B & L Soothe Lubricant Eye Drops, Liposic EDO, OcuFresh Eye Wash
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Meibomian Gland Dysfunction, Posterior Blepharitis
Efficacy of Zylet vs. Lotemax for the Treatment of Ocular Surface Inflammation/MGD/Blepharitis
This is a Phase IV, single site, randomized, double masked, parallel control clinical trial of 60 subjects to investigate the variance of efficacy between Lotemax® and Zylet® for treatment of ocular surface inflammation due to…
- Trial name
- ZvL (NCT01456780)
- Testing
- Loteprednol/tobramycin, Loteprednol, B+L Advanced Eye Relief Lubricant Drop
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts Eye and Ear Infirmary