Clinical trials: Oculomotor System
Biological Clock Dysfunction, Optic Nerve Hypoplasia
Biological Clock Dysfunction in Optic Nerve Hypoplasia
Background: Optic Nerve Hypoplasia (ONH) is a leading cause of blindness in children. For unclear reasons, the incidence of ONH is increasing, with ONH affecting about 1 in 10,000 live-born infants.
- Trial name
- NCT00825591
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Yale University
Spinocerebellar Ataxia Type 3, Machado-Joseph Disease
Natural History of Oculomotor Neurophysiology in Ataxic and Pre-ataxic Carriers of SCA3/MJD
The study will consist of a prospective observation of subjects in a natural history design. Disease progression will be monitored through clinical scales and video-oculography.
- Trial name
- BIGPRO (NCT04229823)
- Testing
- Video-oculography, Clinical Scales, Genotyping
- Where
- Brazil
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Brain Injuries
Pilot Study of Individualized Neurovisual Rehabilitation Following Acquired Brain Injury
This prospective single-group pilot study will evaluate the feasibility and preliminary outcomes of an individualized neurovisual rehabilitation program for adults with visual impairment following acquired brain injury.
- Trial name
- NCT07849582
- Testing
- Individualized Neurovisual Rehabilitation
- Where
- Czechia
- Volunteers
- 30 people
- Sponsor
- Charles University, Czech Republic
Cerebral Palsy Spastic Diplegia
Oculomotor Training in Spastic Diplegia: Effects on Postural Stability and Motor Proficiency
This randomized clinical trial investigates the effect of oculomotor training on postural stability and motor proficiency in children with spastic diplegia.
- Trial name
- NCT07731074
- Testing
- Oculomotor Training, Conventional Physiotherapy
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Cairo University
Elderly, Proprioception, Postural Balance
Neck Integration and Eye Movement Training for Fall Risk in the Elderly
Age is one of the primary risk factors for falls, with risk increasing as people get older. Research on fall risk and prevention has identified hundreds of contributing factors, showing that falls have complex and multifactorial…
- Conditions
- Elderly, Proprioception, Postural Balance, Oculomotor System
- Trial name
- NCT07167979
- Testing
- Combining neck muscle strengthening with oculomotor saccade tasks., Neck Strengthening Only
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University
Oculomotor Nerve Palsy, Trochlear Nerve Palsy
A Retrospective Study of the Effects of Ocular Acupuncture on Ocular Motor Nerve Palsy
This retrospective observational study is designed to assess the response to treatment with ocular acupuncture and its relative factors, in terms of diplopia status, ocular motility differences, and clinical features, in ocular…
- Conditions
- Oculomotor Nerve Palsy, Trochlear Nerve Palsy, Abducens Nerve Paralysis
- Trial name
- NCT03461809
- Testing
- Ocular acupuncture
- Volunteers
- 900 people
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Healthy, Dystonia
Abnormal Movements, Cerebellum and Sensorimotor : Oculomotor Study
Dystonia is a movement disorder characterized by involuntary, sustained, often repetitive muscle contractions of opposite muscles that lead to abnormal twisting movements or odd postures.
- Conditions
- Healthy, Dystonia, Parkinson Disease
- Trial name
- MOUVADOC (NCT01495897)
- Testing
- Tracking eye movement, Tracking eye movement under deep brain stimulation
- Where
- France
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Vision Disorders
Effect of Lens Presentation on the Clinical Oculomotor Assessment at Near
This study will compare near clinical oculomotor parameters (heterophoria, vergence ranges, AC/A and accommodative findings) measured when lenses and/or prisms are introduced using three different instruments namely: (i) a…
- Trial name
- NCT02679313
- Testing
- Phoropter
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Carotid Artery Stenoses
SPI-guided Analgesia During CEA Under RA
The aim of this randomized prospective trial is to assess the utility of Adequacy of Anaesthesia technique (Response Entropy and Surgical Pleth Index) for monitoring pain perception intraoperatively, maintainance of hemodynamic…
- Trial name
- CEA (NCT04500249)
- Testing
- infiltration rescue intraoperative analgesia, rescue IA, rescue antyhypertensive medication
- Where
- Poland
- Volunteers
- 105 people
- Sponsor
- Medical University of Silesia
Möbius Sequence
Impairments of Oral Language in Mobius Syndrome
The Möbius syndrome constitutes a congenital disorder classically caused by genetic and environmental factors. The clinical manifestations include lesion of the facial and abducens nerves associated with limb malformations…
- Trial name
- Mobius (NCT00856531)
- Sponsor
- Fortaleza University
Convergence Insufficiency
Effect of Oculomotor Therapy in Individuals With Convergence Insufficiency
The aim of this study is to investigate the effect of oculomotor therapy in individuals with ocular convergence insufficiency.
- Trial name
- NCT07036263
- Testing
- Oculomotor therapy, No Treatment Added
- Volunteers
- 70 people
- Sponsor
- University of Nove de Julho
Stroke, Oculomotor; Disorder
Oculomotor and Cognitive Rehabilitation Using Visual Feedback in Stroke Patients
Investigators will test the effectiveness of oculomotor cognitive training using eye tracker-based device during rehabilitation course in patients with a degree of disability no more than 3 points on a scale Rankin.
- Conditions
- Stroke, Oculomotor; Disorder, Attention Disturbances
- Trial name
- NCT05309148
- Testing
- Training on eye tracker based device, Training with a neuropsychologist, Training on eye tracker based device and with a neuropsychologist
- Where
- Russia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Federal Center of Cerebrovascular Pathology and Stroke, Russian Federation Ministry of Health
Acquired Brain Injury
VR-based Remote Rehabilitation for Pediatric ABI
The primary objective of this study is to evaluate the feasibility and effectiveness of an at-home program of VR-based vestibular and oculomotor rehabilitation on improving postural stability, ocular motility and activities of…
- Trial name
- NCT05052905
- Testing
- LibraVR
- Where
- Israel
- Volunteers
- 2 people
- Sponsor
- Libra At Home LTD
Parkinson Disease, Idiopathic
Video-oculography and Parkinson's Disease
This study aims to study, in patient with Parkinson's disease, mild to moderate stage (according to Movement Disorder Society Clinical Diagnostic Criteria for Parkinson's Disease, Postuma et al., 2015): the evolution of…
- Trial name
- NCT04731246
- Testing
- Video-oculography / Neuropsychological evaluations
- Where
- Monaco
- Volunteers
- 30 people
- Sponsor
- Association de Recherche Bibliographique pour les Neurosciences
PARKINSON DISEASE (Disorder)
Oculomotor-Pupillary AI Biomarkers in Parkinson's
The goal of this prospective observational study is to investigate whether oculomotor-pupillary abnormalities detected using a novel edge-AI eye-tracking device can serve as objective and quantitative biomarkers for the early…
- Trial name
- NCT07886450
- Testing
- Edge-AI Eye-Tracking Assessment
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Brain Injuries, Concussion, Brain
The Monaco Initiative for Concussion in Motorsport Pilots
The study aims: to observe a population particularly exposed by the past to brain trauma and concussion: Motorsport Pilots who are retired from a professional practice of motor sport; to report results of their neuro-cognitive…
- Conditions
- Brain Injuries, Concussion, Brain, Sport Injury
- Trial name
- NCT04730167
- Testing
- Neurological and neuropsychological assessments / MRI / PET scan / Video-oculography.
- Where
- Monaco
- Volunteers
- 12 people
- Sponsor
- Association de Recherche Bibliographique pour les Neurosciences
Temporomandibular Disorder, Temporomandibular Joint Disorders
Effect of Exercises on Convergence Insufficiency in Individuals With Temporomandibular Disorders
Temporomandibular Disorder is a disorder that involves the muscles of mastication, the temporomandibular joint (TMJ), and associated structures.
- Conditions
- Temporomandibular Disorder, Temporomandibular Joint Disorders, Temporomandibular Joint Dysfunction Syndrome, Convergence Insufficiency
- Trial name
- NCT05761106
- Testing
- Oculomotor Therapy, Therapy for Temporomandibular Disorder
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- University of Nove de Julho
Inattention, Cognitive Training
RECOGNeyes Gaze-Control Training
RECOGNeyes is a computer game developed by members of the research team to improve attention in people who find it hard to "keep their eyes on the task".
- Conditions
- Inattention, Cognitive Training, Cognitive Control, Oculomotor Dysfunction
- Trial name
- NCT06691646
- Testing
- Gaze-control training game
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Concussion
Oculomotor Rehabilitation After Concussion in Adults: A Feasibility Study
After concussion, many individuals experience vision-related symptoms such as blurred vision, difficulty reading, and discomfort in visually stimulating environments, which can interfere with return to work, school, and daily…
- Trial name
- ORCA (NCT07709936)
- Testing
- Usual Care, Oculomotor exercises delivered in virtual reality
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
MTBI - Mild Traumatic Brain Injury
Validation of Clinical Outcome Measures Specific to mTBI-Related Oculomotor Disorders
The specific aim of this project is to validate clinical tests to be used as outcome measures in studies of mTBI-related vision problems.
- Trial name
- NCT07282691
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Salus University