Clinical trials: Off Pump Coronary Artery Bypass Graft
Coronary Artery Disease, Graft Failure
Clinical Effect of No-touch Harvesting Technique in OPCABG
This study aims to investigate the clinical effect of the new saphenous vein harvesting technique "No-touch" in off-pump coronary artery bypass grafting(OPCABG), comparing to the conventional technique.
- Trial name
- NCT03729531
- Testing
- Conventional vein harvesting technique, no-touch vein harvesting technique
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Artery Disease
On-pump Versus Off-pump Coronary Artery Bypass Grafting , Short Term Outcomes , Sohag Experience
Coronary artery disease (CAD) and its sequlae, such as myocardial infarction, arrhythmia and heart failure, are among the leading causes of death around the world .
- Trial name
- NCT06069986
- Testing
- coronary artery bypass graft CABG
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Sohag University
Patients Undergoing Off-pump Coronary Artery by Pass Surgery
Predictive Value of Postoperative Prognostic Nutritional Index Trajectory on 1-year Mortality After Off-pump Coronary Artery Bypass Surgery
This study investigated the changing pattern of postoperative Prognostic Nutritional Index (PNI) after off-pump coronary artery bypass surgery using a trajectory analysis.
- Trial name
- NCT06435416
- Testing
- No intervention
- Where
- South Korea
- Volunteers
- 983 people
- Sponsor
- Gangnam Severance Hospital
Coronary Artery Bypass Graft
High Frequency Ventilation During Off Pump Coronary Artery Bypass Graft (CABG)
This study is to test the safety of high frequency-low volume ventilation during off pump coronary artery bypass as reflected in the near infrared spectroscopy values for cerebral oxygenation.
- Trial name
- VHF (NCT00863044)
- Testing
- Apnea, High frequency ventilation
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Montreal Heart Institute
Coronary Artery Bypass, Off-Pump, Minimally Invasive Cardiac Surgery
MInithoraCotomy vs Sternotomy for Multivessel Coronary Artery Bypass Grafting: A Partially Randomized Patient Preference Trial Assessing Quality of Life and Patency Outcomes
This trial will address essential questions of the efficacy and safety of MICS-CABG in addition to the quality of life and patency rate of the grafts.
- Trial name
- NCT04795193
- Testing
- Minimal invasive coronary surgery, Off-pump coronary artery bypass surgery
- Where
- China
- Volunteers
- 248 people
- Sponsor
- Peking University Third Hospital
Acute Coronary Syndrome (ACS)
Effect of Perioperative Clopidogrel Responsiveness on Ischemic Outcome in Patients With Acute Coronary Syndrome Undergoing Off-pump Coronary Artery Bypass Surgery
The whole blood Thrombelastograph (TEG®) Platelet Mapping™ assay measures clot strength, maximal amplitude (MA), reflecting maximal platelet function, and detects the reduction in platelet function, presented as percentage…
- Trial name
- NCT02184884
- Testing
- MACE after OPCAB, without MACE after OPCAB
- Where
- South Korea
- Volunteers
- 195 people
- Sponsor
- Yonsei University
Coronary Artery Disease, Coronary Stenosis
Enhanced Recovery After Surgery (ERAS) in Coronary Artery Bypass Graft / Off Pump Coronary Artery Bypass (CABG/OPCAB)
It has been assumed that some elements of the ERAS protocol may contribute to the reduction of complications and improve the satisfaction of patients undergoing coronary artery bypass surgery.
- Trial name
- NCT03956420
- Testing
- Premedication visit, Preoperative period, Postoperative period
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Silesian University of Medicine
Cardiac Surgery
Effects of Colloid and Crystalloid on the Microcirculatory Alterations During Off-pump Coronary Artery Bypass Surgery
The purpose of this study is to compare the effects of crystalloid and colloid, which are used for pump priming solution, on the microcirculatory alterations during cardiac surgery.
- Trial name
- NCT01713166
- Testing
- plasmalyte solution, Hextend
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Seoul National University Hospital
Ischemic Heart Disease, Coronary Artery Bypass Grafting
Evaluation of Outcomes of Coronary Artery Bypass Grafting.
Evaluation of outcomes of coronary artery bypass grafting.
- Trial name
- EOCABG (NCT03786939)
- Testing
- On-pump CABG., Off-pump CABG., Pump-assisted CABG.
- Where
- Russia
- Volunteers
- 1,000 people
- Sponsor
- St. Petersburg State Pavlov Medical University
Coronary Artery Disease, Off Pump Coronary Artery Bypass Surgery
Early Cardioprotective Effect of Sevoflurane
In vitro studies and in vivo animal experiments have shown that halogenated volatile anesthetics have a protective effect on the ischemic myocardium.
- Trial name
- NCT00477737
- Testing
- Sevoflurane, propofol
- Where
- Croatia
- Volunteers
- 32 people
- Sponsor
- University Hospital Dubrava
Coronary Artery Bypass Grafting, Remote Ischemic Conditioning
Safety and Efficacy of Remote Ischemic Conditioning for Patients Taking Off-pump Coronary Artery Bypass Grafting
Remote ischemic conditioning (RIC) is the process of repeated ischemia and reperfusion in the peripheral vessels, which is proved in reducing IRI in vital organs.
- Conditions
- Coronary Artery Bypass Grafting, Remote Ischemic Conditioning, Ischemia-Reperfusion Injury
- Trial name
- IMPROVE (NCT06141525)
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 648 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Coronary Artery Bypass Graft Triple Vessel
Effect of Prewarming on Microcirculatory Response
Intraoperative hypothermia may affect tissue microcirculation and can induce myocardial injury, wound infection, and coagulopathy.
- Trial name
- NCT02186210
- Testing
- prewarming
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Heart Disease
German Off Pump Coronary Artery Bypass in Elderly Study
Comparison of two operative techniques (on-pump vs off-pump)of coronary revascularisation of the best treatment concept for patients older or 75 years old.
- Trial name
- GOPCABE (NCT00719667)
- Testing
- coronary artery bypass grafting
- Where
- 2 sites in Germany
- Volunteers
- 2,000 people
- Sponsor
- German Off Pump Coronary Artery Bypass in Elderly Study Group
Microcirculation, Anesthetic Complication Spinal
Effect of Anesthetics on Microcirculation in Patients Undergoing Off-pump Coronary Artery Bypass Surgery
Volatile anesthetics, such as sevoflurane and desflurane, are commonly used in patients undergoing cardiac surgeries including off-pump coronary artery bypass.
- Trial name
- NCT03209193
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Seoul National University Hospital
Coronary Artery Disease, Diabetes
Predictability of Preoperative Hemoglobin A1c in Diabetic Patients Underwent Off-Pump Coronary Artery Bypass Surgery: A Retrospective Study.
The aim of this study is to evaluate evaluated the impact of preoperative HbA1c in diabetic patients on perioperative glycemic variability and outcome after off-pump coronary artery bypass (OPCAB).
- Trial name
- NCT03543449
- Testing
- Off-Pump Coronary Artery Bypass (OPCAB) surgery
- Where
- South Korea
- Volunteers
- 703 people
- Sponsor
- Yonsei University
Coronary Artery Occlusive Disease(CAOD)
The Effect of Balanced Crystalloid Versus 5% Albumin on Endothelial Glycocalyx Degradation in Patients Undergoing Off-pump Coronary Artery Bypass Surgery
It is being revealed that the more severe the damage of the endothelial glycocalyx (EG) layer, the more likely it is that the prognosis of the patients is poor.
- Trial name
- NCT03699462
- Testing
- Plasma solution-A injection, 5% Albumin
- Where
- South Korea
- Volunteers
- 106 people
- Sponsor
- Yonsei University
Acute Kidney Injury
Effect of Sodium Bicarbonate on Prevention of Acute Kidney Injury in High Risk Patients Undergoing Off-pump Coronary Artery Bypass (OPCAB)
In this single-site, randomized, controlled and double-blind clinical trial, the investigators evaluate the effect of sodium bicarbonate on prevention of acute kidney injury in high risk patients undergoing off pump coronary…
- Trial name
- NCT01840241
- Testing
- sodium bicarbonate, normal saline
- Where
- South Korea
- Volunteers
- 162 people
- Sponsor
- Yonsei University
Postoperative Cognitive Dysfunction (POCD)
Cohort Study of Postoperative Cognitive Dysfunction After Off-Pump Coronary Artery Bypass Grafting
This prospective cohort study aims to investigate postoperative cognitive dysfunction in patients undergoing off-pump coronary artery bypass grafting. Eligible patients will be enrolled before surgery and followed after surgery.
- Trial name
- OPCAB-POCD (NCT07643194)
- Testing
- Off-Pump Coronary Artery Bypass Grafting
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Artery Occlusive Disease
Effects of Ulinastatin on Coagulation in High Risk Patients Undergoing Off Pump Coronary Artery Bypass Graft Surgery
Ulinastatin reduce the amount of bleeding and fibrinolysis in high risk patients undergoing off-pump coronary bypass surgery (OPCAB).
- Trial name
- NCT01084044
- Testing
- ulinastatin, saline solution
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Yonsei University
Coronary Artery Occlusive Disease
The Effect of 6% Hydroxyethyl Starch 130/0.4 on Blood Loss and Coagulation in Patients Medicated With Antiplatelet Agents Prior to Off-Pump Coronary Bypass Graft Surgery
HES 130/0.4 significantly solution will not affect on coagulation and blood loss in patients medicated with antiplatelet agents prior to off-pump coronary bypass surgery (OPCAB).
- Trial name
- NCT01051206
- Testing
- 6% hydroxyethyl Stach 130/0.4
- Where
- South Korea
- Volunteers
- 106 people
- Sponsor
- Yonsei University