Clinical trials: Old Age; Atrophy
Cognition Disorders in Old Age, Cognitive Function
Impact of Nutrition, Sleep, and Physical Activity on Intellectual Function and Muscle Mass in Older Adults
The goal of this prospective, single site, interventional randomized control trial is to treat age related health conditions in adults older than 65 years and functional independence.
- Conditions
- Cognition Disorders in Old Age, Cognitive Function, Frailty/Sarcopenia, MCI
- Trial name
- INSPIOR (NCT06135740)
- Testing
- Fitbit wearing, with notification for sleep, activity and nutrition based fitbit data, Routine care
- Where
- Japan
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- Tokyo University
Presbyphonia
Creatine Supplementation for Improved Voice Performance in the Elderly
The primary objective of this study is to determine if creatine supplementation improves acoustic, auditory perceptual, physiologic, and patient-reported outcome measures in patients over 65 years of age.
- Trial name
- NCT05856916
- Testing
- Creatine monohydrate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health
Sarcopenia, Muscular Atrophy
Exercise and Nutrition Interventions in Age-related Sarcopenia
This project will investigate the synergistic effects of Aerobic and Resistance type Exercise, in combination with Protein Supplementation, on; Body Composition, Musculoskeletal Functioning, Nutritional Status and Quality of Life…
- Trial name
- NCT02912130
- Testing
- Protein Supplementation, Aerobic Exercise, Resistance Exercise
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Liverpool Hope University
Sarcopenia in Elderly
A Study of PLH-2301 in Subjects With Sarcopenia
This is a Phase 2, randomized, double-blind, placebo-controlled, parallel-group study to evaluate the efficacy and safety of PLH-2301 in subjects with sarcopenia.
- Trial name
- PLH-2301_P2 (NCT07390552)
- Testing
- PLH-2301
- Where
- 5 sites in South Korea
- Volunteers
- 168 people
- Sponsor
- Pluto Inc.
Muscle Loss
Galactooligosaccharide and Aging
Sarcopenia is a progressive muscle disease, most commonly affecting older individuals, that is categorised by 1) low muscle strength, 2) low muscle quantity or quality, and 3) low physical performance.
- Trial name
- NCT06411964
- Testing
- Prebiotic
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Bath
Parkinson's Disease, Multiple System Atrophy
Magnetic Resonance Imaging in the Diagnosis of Parkinsonian Syndromes
Parkinsonian syndrome is clinically characterized by the presence of resting tremor, rigidity, bradykinesia and postural instability.
- Conditions
- Parkinson's Disease, Multiple System Atrophy, Progressive Supranuclear Palsy, Vascular Parkinsonism
- Trial name
- PARKIMAGE (NCT02445469)
- Testing
- MRI exam of the brain
- Where
- France
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Joint(S) Degeneration, Old Age; Atrophy
Association Between Fear of Falling and Spinal Stiffness.
1. / evaluation of the fear of falling using an FES-I questionnaire, distribution of subjects according to the score into 3 groups (16-19: little concerned by the fear of falling, 20-27 moderately concerned, 28-64 very concerned…
- Conditions
- Joint(S) Degeneration, Old Age; Atrophy, Fear of Injury
- Trial name
- RAAPC (NCT05134038)
- Testing
- anthropomorphic measurements
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hopital of Melun
Sarcopenia
Feasibility of a Resistance Exercise and Dietary Protein Intervention in Elderly People in Practice (ProMuscle 65PK)
The purpose of this pilot study is to investigate the feasibility and potential impact of a combined resistance exercise and increased protein intake intervention in (frail) elderly, in a real-life setting.
- Trial name
- NCT02434289
- Testing
- Dietary protein products, Resistance exercise training
- Where
- Netherlands
- Volunteers
- 23 people
- Sponsor
- Wageningen University
HEALTHY
Biological Aging of Skeletal Muscles in Humans
Aging affects almost all the tissues and physiological functions, and skeletal muscle is the most affected organ. The progressive decline of the weight and the muscular function linked to the aging contributes to the lack of…
- Trial name
- BioAge (NCT02675192)
- Testing
- Proof cohort : muscular assessment
- Where
- France
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Sarcopenia, Aged
HIT Training in the Frail Elderly.
This pilot study aims to investigate whether high intensity interval training can result in rapid improvements in physical fitness amongst the frail elderly (over 70 years old).
- Conditions
- Sarcopenia, Aged, Exercise, Preoperative Care
- Trial name
- eHIT (NCT03138265)
- Testing
- HIIT Device: ergometer
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Sarcopenia, Sarcopenia in Elderly
Determination of Skeletal Muscle Mass Index Values in the Turkish Population Using Dual Energy X-Ray Absorptiometry
Sarcopenia is defined by the European Working Group on Sarcopenia in Older People (EWGSOP) as "a syndrome characterized by progressive and generalized loss of skeletal muscle mass and strength, carrying a risk of adverse outcomes…
- Trial name
- NCT07510009
- Where
- Turkey (Türkiye)
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Sarcopenia in Elderly
Feasibility of Pre-Conditioning FRT in Sarcopenia
This study aims to assess whether a short, structured exercise programme is suitable and acceptable for older adults with early-stage muscle weakness (known as probable sarcopenia).
- Trial name
- NCT07756762
- Testing
- Pre-Conditioning Functional Resistance Exercise Program
- Volunteers
- 30 people
- Sponsor
- University of Hull
Sarcopenia
Outcome of Exercise With a Towel in Elderly With Sarcopenia
As the proportion of older adults increases, elderly-related issues attract more attention. Sarcopenia is one of the popular elderly-related issues.
- Trial name
- NCT03258827
- Testing
- Exercise with a towel, Home-based exercise
- Where
- Taiwan
- Volunteers
- 53 people
- Sponsor
- Chang Gung Memorial Hospital
Sarcopenia in Elderly, Frailty at Older Adults
Exergaming-based Sitting Tai Chi for Sarcopenia and/or Frailty
This randomized controlled trial will evaluate the effects of an exergaming-based sitting Tai Chi program on muscle strength, physical function, cognition, and psychosocial outcomes in older adults living in residential care…
- Trial name
- NCT07616219
- Testing
- Exergaming-based sitting Tai Chi, General health education
- Where
- Hong Kong
- Volunteers
- 152 people
- Sponsor
- Hong Kong Metropolitan University
Sarcopenia in Elderly, Cachexia; Cancer; Sarcopenia
Body Composition in Older Adults
The primary aim of the study is to explore body composition in older adults (aged 70 years and over) with cancer, undergoing systemic anticancer treatment.
- Conditions
- Sarcopenia in Elderly, Cachexia; Cancer; Sarcopenia, Body Composition Changes, Older Adults
- Trial name
- BODI (NCT06630754)
- Testing
- No Intervention: Observational Cohort
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Protein Malabsorption, Nutrition Disorders
Bioavailability of Proteins From Plant Based Diets
The quality of protein intake has an important role within the nutritional needs of people throughout their lives around the world, particularly in developing countries and in particular during pregnancy and early childhood.
- Conditions
- Protein Malabsorption, Nutrition Disorders, Sarcopenia
- Trial name
- NCT03492190
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Eduardo Ferriolli
Muscle Loss in Elderly
The Effects of Resistance Training and Protein Supplementation in Healthy Elderly Men and Women.
The main objective of this study is to examine the effects of resistance type exercise training combined with nutritional support on body composition and muscle characteristics in healthy elderly men and women.
- Trial name
- NCT01004588
- Testing
- Protein drink
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Sarcopenia, Muscle Atrophy
Concurrent Assessment of Skeletal Muscle Mass and Synthesis/Breakdown in Old Age
This study involves minimally-invasive techniques to measure muscle mass, muscle protein breakdown and synthesis simultaneously in older age.
- Trial name
- NCT04114383
- Testing
- D3-Creatine, Deuterium Oxide, D3-3-methylhistidine
- Where
- United Kingdom
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Frailty, Disability Physical
Viability of an Educational Program for Lifestyle Changes and an Algorithm for the Derivation of Exercise Programs in Older People at Risk of Dependency at Primary Care.
According to the INE in 2021, more than 9 million people are currently over 65 years of age. This means that more than 1 million are frail and almost 4 million are pre-fragile only in Spain.
- Conditions
- Frailty, Disability Physical, Old Age; Atrophy
- Trial name
- PRICA-POWFRAIL (NCT05772910)
- Testing
- EDUcation, EXERcise, EDU-EXER
- Volunteers
- 110 people
- Sponsor
- University of Cadiz
Inflammation, Oxydative Stress
Physical Activity Oxidative Stress and Inflammation With Ageing
Sarcopenia, an age-related decline in muscle function, are thought to be influenced by oxidative stress and low-grade inflammation, resulting in significant muscle mass reduction and altered physical performance.
- Conditions
- Inflammation, Oxydative Stress, Sarcopenia, Older Patient
- Trial name
- POXI-AGEING (NCT06980896)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Nantes University Hospital