Clinical trials: Old Age; Atrophy, open to volunteers
Sarcopenia in Elderly, Frailty/Sarcopenia
Frailty in the Elderly Oncological and Oncohematological Patient.
The Italian population is progressively aging, and cancer incidence increases with age. Older patients are at higher risk of frailty, a condition associated with adverse outcomes such as disability, falls, hospitalization, and…
- Conditions
- Sarcopenia in Elderly, Frailty/Sarcopenia, Oncological Patients, Hematologic Disease
- Trial name
- SALICE (NCT07624370)
- Testing
- Frailty evaluation
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- Azienda Socio Sanitaria Territoriale Ovest Milanese, Ospedale di Legnano
Sarcopenia in Elderly
Evaluation of the Effect of a Seaweed Flour- and Leucine-Enriched Food on Metabolic and Inflammatory Status in Older Adults With Probable Sarcopenia or Sarcopenia
Sarcopenia and probable sarcopenia are associated with loss of muscle strength, functional impairment, frailty, and an increased risk of adverse outcomes in older adults.
- Trial name
- NCT07689994
- Testing
- Standard chocolate-flavored cake, Leucine-Enriched Chocolate Cake, Leucine Plus Seaweed Flour-Enriched Chocolate Cake
- Where
- Chile
- Volunteers
- 102 people
- Sponsor
- Finis Terrae University
Sarcopenia
Case Control in Sarcopenia Among Elderly Type 2 Diabetic Patients
1. Assess sarcopenia prevalence in elderly diabetic patients. 2. Evaluate impact of diabetes and its medications on muscle health. 3. detect effect of sacropenia on quality of life on elderly
- Trial name
- NCT07244601
- Testing
- muscle ultrasound
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eman Alaa Eldean Mohamed
Sarcopenia
Efficacy on Walking Ability of Electroacupuncture Therapy in Elderly Patients With Sarcopenia
Introduction: The efficacy of existing therapies for the treatment of sarcopenia is still not satisfactory. Therefore, this randomized controlled, assessor-blinded study was designed to investigate the efficacy and safety of…
- Trial name
- NCT05431010
- Testing
- electroacupuncture, Rehabilitation Training
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Sarcopenia in Elderly, Sarcopenic Obesity
Comparative Analysis of Sarcopenia in Rehabilitation Outcomes Following Femoral Neck Fracture: a Study in Normal Weight and Obese Study Cohort
Impact of Obesity on Sarcopenia Prevalence and Severity in Elderly Adults Recovering from Femoral Neck Fractures: A Prospective Study Introduction Age-related muscle loss, or sarcopenia, which includes reductions in both muscle…
- Conditions
- Sarcopenia in Elderly, Sarcopenic Obesity, Frailty, Femoral Fractures
- Trial name
- NCT06705166
- Volunteers
- 300 people
- Sponsor
- Shmuel Harofeh Hospital, Geriatric Medical Center
Heart Failure with Preserved Ejection Fraction (HFPEF), Heart Failure with Reduced Ejection Fraction
Feasibility and Effectiveness of Eccentric Exercise in Sarcopenic Older Adults with Heart Failure: a Pilot Study
This study is designed to evaluate the safety, feasibility, and effectiveness of a 12-week eccentric exercise program for older adults with sarcopenia (muscle loss) or sarcopenic obesity and chronic heart failure (HF).
- Conditions
- Heart Failure with Preserved Ejection Fraction (HFPEF), Heart Failure with Reduced Ejection Fraction, Sarcopenia in Elderly, Sarcopenic Obesity
- Trial name
- ECLYPSE-HF (NCT06826963)
- Testing
- Aerobic eccentric intervention
- Where
- 2 sites in Italy
- Volunteers
- 15 people
- Sponsor
- Universita di Verona
Frailty at Older Adults, Sarcopenia
A Clinical Study on the Improvement of Frailty and Sarcopenia in Elderly Community Residents Through Pulsed Electromagnetic Field Therapy
The entire clinical study will be conducted strictly following the following procedure: 1) Informed Consent If you decide to participate in this trial, we will first ensure that you fully understand the research purpose…
- Trial name
- NCT07834697
- Testing
- Standard treatment with pulsed magnetic therapy apparatus, Fake stimulation therapy with pulse magnetic therapy device
- Volunteers
- 100 people
- Sponsor
- Xuanwu Hospital, Beijing
Hip Fracture, Malnutrition
GNRI and Rectus Femoris Muscle Thickness in Older Patients Undergoing Hip Fracture Surgery
This prospective observational study will evaluate whether nutritional risk and reduced muscle mass are associated with postoperative outcomes in adults aged 65 years or older undergoing surgery for hip fracture.
- Conditions
- Hip Fracture, Malnutrition, Sarcopenia, Postoperative Complications
- Trial name
- NCT07751692
- Testing
- Geriatric Nutritional Risk Index Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
The Association Between Sarcopenia and the Strength of Peripheral and Respiratory Muscles in Elderly Individuals, Cardiovascular Diseases
The Association Between Sarcopenia and the Strength of Peripheral and Respiratory Muscles in Elderly Individuals
Population aging is a significant global trend, with projections indicating that by 2050, 1 in 6 individuals worldwide will be over 65 years old, compared to 1 in 11 in 2019.
- Conditions
- The Association Between Sarcopenia and the Strength of Peripheral and Respiratory Muscles in Elderly Individuals, Cardiovascular Diseases, Diabetes Mellitus, Hypertension
- Trial name
- NCT06756399
- Testing
- Questionnare, hand grip and respiratory muscle strength
- Volunteers
- 100 people
- Sponsor
- Biruni University
Sarcopenia in Elderly
Feasibility of Egg White Pudding Supplementation for Individuals in Personal Care Home Centres Needing Dietary Supplementation
This trial is an open-label randomized controlled parallel arm feasibility trial. 54 residents in care homes receiving nutrition supplementation (minimum 40% of each sex, ≥ 50 years of age).
- Trial name
- NCT07805993
- Testing
- Egg White Pudding, Nestle Resource
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Seven Oaks Hospital Chronic Disease Innovation Centre
Sarcopenia in Elderly, Hospital Associated Disability
Preventing Hospital Associated Disability in Older Patients: Individualized Nutrition and Exercise Strategy
Aproximately a third of persons older than 70 years lose physical function and ability to take care of themselves during a stay at a hospital. This is associated to an increased risk of readmission and mortality.
- Conditions
- Sarcopenia in Elderly, Hospital Associated Disability, Malnutrition Elderly, Physical Function
- Trial name
- PrevHAD RCT (NCT07373587)
- Testing
- Exercise
- Where
- Denmark
- Volunteers
- 360 people
- Sponsor
- Bispebjerg Hospital
Colorectal Cancer, Sarcopenia
Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer
This study will examine the association between low muscle mass (myopenia) at diagnosis and chemotherapy toxicity in older adults with newly diagnosed advanced colorectal cancer.
- Trial name
- M&M (NCT03998202)
- Where
- 147 sites in United States
- Volunteers
- 300 people
- Sponsor
- Wake Forest University Health Sciences
Osteoarthritis (Knee / Hip), Sarcopenia
Preoperative Muscle Stiffness, Functional Reserve, and Postoperative Quality of Recovery in Lower Extremity Arthroplasty
In elderly patients undergoing arthroplasty surgery, postoperative recovery quality is closely related to preoperative physical reserve. Sarcopenia and reduced muscle quality can increase postoperative complications.
- Conditions
- Osteoarthritis (Knee / Hip), Sarcopenia, Postoperative Recovery
- Trial name
- PRE-QoR (NCT07879209)
- Testing
- Handgrip Strength (HGS) Measurement, Ultrasound Shear Wave Elastography (SWE)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara Etlik City Hospital
Femur Fractures, Frailty
Predicting of Frailty
This study aims to evaluate the frailty status of elderly patients undergoing surgery for hip fractures (femur trochanteric fractures).
- Conditions
- Femur Fractures, Frailty, Sarcopenia
- Trial name
- PRE-FRAIL (NCT07332052)
- Testing
- Clinical and Functional Assessment, Rectus femoris thickness measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- ali ihsan uysal
Old Age; Atrophy
The Effect of a Combined Personalized Nutritional Intervention and a Personalized Graded Activity Functional Training Program on Physical Performance in Hospitalized Older Patients, Compared to Usual Care
This project aims to improve physical performance in older patients, by offering a personalized combined nutritional intervention with a physical activity training program.
- Trial name
- FITFOOD (NCT05413616)
- Testing
- FITFOOD lifestyle intervention
- Where
- Netherlands
- Volunteers
- 136 people
- Sponsor
- Radboud University Medical Center
Sarcopenia in Elderly, Frailty at Older Adults
Exergaming-based Sitting Tai Chi for Sarcopenia and/or Frailty
This randomized controlled trial will evaluate the effects of an exergaming-based sitting Tai Chi program on muscle strength, physical function, cognition, and psychosocial outcomes in older adults living in residential care…
- Trial name
- NCT07616219
- Testing
- Exergaming-based sitting Tai Chi, General health education
- Where
- Hong Kong
- Volunteers
- 152 people
- Sponsor
- Hong Kong Metropolitan University
Sarcopenia, Sarcopenia in Elderly
Acute Sarcopenia in Hospitalized Older Adults
Acute sarcopenia is a rapid decline in muscle mass and function occurring within 28 days of a major stressor, such as hospitalization, infection, or surgery. It is frequent but often underdiagnosed in older adult.
- Trial name
- BASIS (NCT07454759)
- Testing
- Acute sarcopenia will be defined as the incidence of sarcopenia compared to baseline measurements at recruitment, using the European Working Group on Sarcopenia in older people 2 (EWGSOP2) criteria
- Volunteers
- 280 people
- Sponsor
- IRCCS San Raffaele
Coronary Disease, Sarcopenia
The Therapeutic Effect of Phase I Cardiac Rehabilitation on Elderly Patients With CHD Complicated by Sarcopenia
The purpose of this clinical trial is to explore whether Phase I cardiac rehabilitation can treat elderly patients with coronary heart disease complicated by sarcopenia.
- Trial name
- NCT07197463
- Testing
- drug therapy （Aspirin, Atorvastatin, Nitroglycerin）+ general treatment（quit smoking）
- Volunteers
- 100 people
- Sponsor
- Qilu Hospital of Shandong University
Cognitive Disorders, Muscular Disorders, Atrophic
Dietary Strategy to Tackle Cognitive and Locomotor Abilities in Early Elderly Subjects
Polyphenols, precisely resveratrol, with red wine as the most substantial source, was associated with improvements in cognitive function.
- Trial name
- WinAging (NCT06871384)
- Testing
- Nonalcoholic red wine group (Intervention group), Drinking water group (Control group)
- Where
- 3 sites in Spain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
COPD (Chronic Obstructive Pulmonary Disease), Sarcopenia in Elderly
The Aim of the Study is to Decipher the Alterations in Signalling Pathways of Skeletal Muscle Stem Cells (Satellite Cells (SCs)) in Individuals With COPD, as Well as to Examine the Effect of Exercise Training on SCs.
The aim of the study is to decipher the alterations in signalling pathways of skeletal muscle stem cells (satellite cells (SCs)) in individuals with COPD, as well as to examine the effect of exercise training on SCs.
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), Sarcopenia in Elderly, Skeletal Muscle Atrophy, Cachexia-Anorexia Syndrome
- Trial name
- SCOOP (NCT07923656)
- Testing
- Exercise training
- Where
- 3 sites in France
- Volunteers
- 26 people
- Sponsor
- University Hospital, Bordeaux