Clinical trials: Old Age; Debility
COVID-19
Developing an Effective Intervention to Address Post-Corona-Virus-Disease-2019 Balance Disorders, Weakness and Muscle Fatigue in Individuals Aged 65+
The long-term consequences and sequelae of COVID-19 are still unclear; however, a vast number of elderly individuals have reported prolonged general weakness and muscular fatigue, leading to significant functional decline…
- Trial name
- NCT05934279
- Testing
- Resistance Training
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Józef Piłsudski University of Physical Education
Frailty, Old Age; Debility
The Effects of a Tele-health Program
Frailty is a state of being vulnerable and functional disable due to age-related decline of multiple physiological systems, and is often associated with higher risk of falls, institutionalization, hospitalization, disability…
- Trial name
- NCT05267444
- Testing
- Individualized motion-based interactive game program
- Where
- Hong Kong
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Accidental Falls, Old Age; Debility
Interventions to Prevent Falls. PRECAISAL Study
This study aims to guide older people living in the community on appropriate strategies within a fall prevention program. This program is aimed at training in physical exercises carried out through group workshops or at…
- Conditions
- Accidental Falls, Old Age; Debility, Activity, Motor
- Trial name
- NCT05070533
- Testing
- Individual treatment, Groupal treatment
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud
Surgery, Old Age; Debility
Pre-surgical Protocol for Frail Elderly People in Order to Reduce Hospitalization Days (APOPM).
Elderly people (EP) have increased, as well as life expectancy at birth. In Chile there are more than 2 million 800 thousand EP, which corresponds to 1/6 of the Chilean population.
- Conditions
- Surgery, Old Age; Debility, Frail Elderly Syndrome, Post-Operative Confusion
- Trial name
- APOPM (NCT04770259)
- Testing
- Timely pre-surgical conditioning
- Where
- 2 sites in Chile
- Volunteers
- 87 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Old Age, Mobility Limitation
RIC (Remote Ischemic Conditioning) in Older Individuals
The purpose of this study is to examine the feasibility and acceptability of a technique called remote ischemic conditioning (RIC) that aims to improve muscle strength, muscle mass, exercise tolerance, resilience (i.e.
- Conditions
- Old Age, Mobility Limitation, Debility
- Trial name
- NCT06476288
- Testing
- Low-intensity resistance exercise training, High-Dose Remote ischemic conditioning (RIC), Low-Dose Remote ischemic conditioning (RIC)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Duke University
Poor Performance Status, Muscle Weakness
SR-WBV Training for Frail Elderly in the Skilling up Stage
This randomized controlled study aims to examine long term effects in the skilling up phase over 4 weeks on physical functional performance and strength of mechanical SR-WBV and dance therapy intervention in a frail elderly…
- Trial name
- NCT01704976
- Testing
- SR-WBV
- Where
- Switzerland
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Bern University of Applied Sciences
Critical Illness, Sarcopenia
Effect of Protein, Mobility Therapy and Electric Stimulation on Recovery in Older ICU Survivors
Older ICU survivors with ICU acquired weakness (ICUAW) are malnourished, sarcopenic, and functionally debilitated as a consequence of the high burden of comorbidities common in the elderly.
- Conditions
- Critical Illness, Sarcopenia, ICU Acquired Weakness
- Trial name
- ProMoTE (NCT05326633)
- Testing
- MRP and High Protein Supplement (HPRO) and Neuromuscular Electric Stimulation (NMES)
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of Maryland, Baltimore
Frailty
Correlation Between Modified Weakness Index and Postoperative Delirium in Elderly Patients
1. To study whether there is a correlation between weakness and postoperative delusions in elderly non-cardiac surgery patients 2. Can the improved debilitating index predict the delusion after non-cardiac surgery 3.
- Trial name
- NCT05189678
- Testing
- No intervention
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Qianfoshan Hospital
Old Age; Debility, Peripheral Neuropathy
Protective Arm Balance Responses
The overall objective of this study is to investigate the effect of attention control training on reach-grasp stabilizing responses during fall-induced perturbations.
- Trial name
- PAT (NCT06388434)
- Testing
- Protective Arm Balance Response Training
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Pelvic Floor Muscle Weakness, Urinary Incontinence in Old Age
Investigation of The Effect of Pelvic Floor Exercise Programme in Elderly.
Alteration of hormonal structure and decreasing of muscle tissue with aging causes pelvic floor dysfunction. Over age of 65 so many factors such as decrease in volume of muscle tissue, decrease in the amount of estrogen /…
- Conditions
- Pelvic Floor Muscle Weakness, Urinary Incontinence in Old Age, Sexual Dysfunction, Quality of Life
- Trial name
- NCT04036604
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Fall Injury, Postural; Defect
Conscious Movement Processing, Postural Stability and Muscle Efficiency in Older Adults
This study aims to address critical knowledge gaps by investigating the effects of trait conscious movement processing propensity on real-time (state) conscious movement processing propensity, postural stability, and muscle…
- Conditions
- Fall Injury, Postural; Defect, Old Age; Debility
- Trial name
- NCT05630911
- Testing
- Standing tasks with different task difficulty
- Where
- China
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Old Age; Debility, Muscle Weakness
Probiotic-Muscle Study
This study will examine the effect of probiotic supplementation (Bacillus coagulans) on muscle protein synthesis in older adults in response to a plant-based diet.
- Conditions
- Old Age; Debility, Muscle Weakness, Protein Deregulation, Protein Deposition
- Trial name
- NCT04297111
- Testing
- Probiotic
- Where
- Ireland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Old Age; Debility
Combined Effects of NMES and LIRT on Muscle Strength, Girth, and Physical Endurance in the Geriatric Population
This study will employ a randomized controlled trial design with a pre-post design to investigate the combined effects of Neuromuscular Electrical Stimulation (NMES) and Low-Intensity Resistance Training (LIRT) on muscle…
- Trial name
- NCT07646405
- Testing
- Neuromuscular electrical stimulation, lOW intensity resistance training
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Weakness, Hospital Acquired Condition
Dedicated Ambulator-assisted Physical Activity to Improve Hospital Outcome Measures in Elderly Patients
Bedrest and lack of mobility in the inpatient hospital setting hastens the functional decline of elderly patients and is associated with increased risk of complications such as falls, delirium, venous thrombosis, and skin…
- Trial name
- NCT02757131
- Testing
- Ambulation
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- The Cleveland Clinic
Old Age; Debility, Fall
Effects of Perturbation-based Balance Training on Postural Control and Cortical Modulation in Elderly With Fall Risk
This is a single-blinded randomized controlled trial with pre- and post- measurements. Forty community-dwelling elderly (age> 65 y/o) with fall risk (defined as functional reach test≦25.4 cm) will be recruited and randomly…
- Trial name
- NCT04473885
- Testing
- Perturbation-based balance training
- Where
- Taiwan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Muscle Weakness, Muscular Atrophy
Physiologic Effects of PRMS & Testosterone in the Debilitated Elderly
This study's primary objective is to determine the independent and combined effects of progressive resistance muscle strength training and testosterone on the development of sustainable improvements in physical function.
- Trial name
- NCT00018356
- Testing
- exercise, testosterone
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- US Department of Veterans Affairs
Hospital Associated Disability, Immobility
Targeting Muscle Strength Loss Due to Hospitalization in Older Adults by Blood-flow Restriction Combined With an Electromyography-driven Serious Game.
This study investigates a new training method designed to help older adults preserve their muscle strength during hospitalization.
- Conditions
- Hospital Associated Disability, Immobility, Older Adults (65 Years and Older)
- Trial name
- GHOSTLY+ (NCT07294131)
- Testing
- Gamified isometric strength training with blood flow restriction, Standard Physiotherapy
- Where
- 3 sites in Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Old Age; Debility, Fall
Implementing an Evidence-based Exercise Program to Reduce Falls in Community-dwelling Older Adults (Otago)
Falls are a major health care problem for seniors. The Otago Exercise Program, which consists of strength and balance training delivered by a physiotherapist, can reduce falls in this population.
- Trial name
- NCT04851405
- Testing
- Otago Exercise Programme+ (OEP+), Otago Exercise Programme (OEP)
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- University of British Columbia
Frail Elderly People Hospitalized
Evaluation of the Hospital Pathway for Frail Elderly Patients Hospitalised for Pathologies Leading to Medical Decompensation
People aged over 75 account for 25% of emergency department visits in the Provence Alpes Côte d'Azur region. Depending on the facility, around 50% of these patients are discharged home without being hospitalised.
- Trial name
- FRAGIL (NCT06873256)
- Where
- France
- Volunteers
- 310 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Frail Elderly Syndrome, Muscle Weakness
Investigation of Relation With Preoperative Fragility and ASA Score in Elderly Patients
Frailty is a term specific to the geriatric period. It is used to describe weak, unstable, frail patients and partially expresses the frailty of the elderly patient.
- Trial name
- NCT05078983
- Testing
- CGA-FI (COMPREHENSIVE GERIATRIC ASSESMENT - FRAILITY INDEX)
- Where
- Turkey (Türkiye)
- Volunteers
- 320 people
- Sponsor
- Gulhane Training and Research Hospital