Clinical trials: Old Age
HIV Infections, Elderly Infection
HIV Resilience Qualitative Study Hong Kong
This qualitative study aims to explore lived experiences of older adults living with HIV in Hong Kong. Twenty older Chinese adults of age 50 or above will be recruited from an HIV specialist clinic providing HIV care in the…
- Trial name
- NCT05021653
- Testing
- no intervention
- Where
- Hong Kong
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
STEMI, Percutaneous Coronary Intervention
Bivalirudin in Elderly Patients With Acute ST-segment Elevation Myocardial Infarction
The study is an investigator-sponsored, prospective, multicenter, randomized, open-label study designed to compare efficacy and safety between bivalirudin and heparin in elderly patients with acute ST-segment elevation myocardial…
- Conditions
- STEMI, Percutaneous Coronary Intervention, Aged
- Trial name
- BEST (NCT03882775)
- Testing
- Bivalirudin, Heparin
- Where
- China
- Volunteers
- 240 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Hodgkin's Disease
Study of Prednisone, Vinblastine, Doxorubicin, and Gemcitabine in Elderly Patients With Advanced Stages Hodgkin's Lymphoma
The objectives of this study are to assess the feasibility and efficacy of a combination chemotherapy (PVAG) in elderly patients with advanced stages Hodgkin's lymphoma.
- Trial name
- NCT00147875
- Testing
- Prednisone, Vinblastine, Doxorubicin (Adriamycin)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University of Cologne
Coronary Artery Disease
Effects of Exercise in Patients With Coronary Artery Disease Aged 80 Years or Older
The purpose of this study is to investigate the effects of exercise for patients with coronary artery disease (CAD) aged 80 years and older, with special reference to maximum aerobic capacity, muscle endurance, physical…
- Trial name
- NCT02025257
- Testing
- Exercise
- Where
- Sweden
- Volunteers
- 34 people
- Sponsor
- Sahlgrenska University Hospital
Elderly (People Aged 65 or More), Vital Signs
Poor Outcomes Among Patients Aged 65 and Older Presenting to the Emergency Department(EDEN-RICAPPS Study)
Our objective is to create and validate predictive models of poor outcome in people over 65 years of age seen in emergency departments.
- Trial name
- EDEN-RICAPPS (NCT07194122)
- Where
- Spain
- Volunteers
- 141,929 people
- Sponsor
- Hospital Galdakao-Usansolo
Social Care, Medical Care
Evaluation of Medical and Social Care for Elderly Patients, Between Hospital and Home: TEMPORARY ACCOMMODATION Out of Hospitalization by Nursing Home and Long-Term Care Units in Ile-de-France Region
Prospective, observational, non-interventional, comparative, multicenter RIPH3 study to investigate the impact of HTSH on length of hospital stay in referring services.
- Conditions
- Social Care, Medical Care, Elderly Patients
- Trial name
- HTSH (NCT06677645)
- Where
- 10 sites in France
- Volunteers
- 258 people
- Sponsor
- Gérond'if
Diastasis Recti Abdominis (DRA), Aging
Risk Factors and Exercise Effects on Abdominal Separation in Seniors
This study aims to evaluate the prevalence of diastasis recti abdominis (DRA) in the geriatric population and assess the effectiveness of a targeted exercise program on inter-recti distance (IRD) and linea alba stability.
- Trial name
- NCT07839572
- Testing
- Abdominal Exercise Program
- Where
- Poland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Acute Vaso Occlusive Crisis (VOC)
L-citrulline Injection in Patients Aged 6-21 Years Old with Sickle Cell Disease Presenting with Vaso-Occlusive Crisis (VOC)
The purpose of this study is to determine if intravenous L-citrulline can abrogate an active vaso-occlusive crisis in sickle cell disease, resulting in decreased pain, reduction or elimination of opiate usage, and reduction or…
- Trial name
- NCT04852172
- Testing
- L-citrulline, D5 1/2NS
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Asklepion Pharmaceuticals, LLC
Transition, Emergencies
The LEARNING WISDOM Phase II Scale up Project
Inspired by the Acute Care for Elders program at Mount Sinai Hospital, this study aims to improve care for elderly patients in four hospitals of Chaudière-Appalaches.
- Conditions
- Transition, Emergencies, Health Care Utilization, Frailty
- Trial name
- NCT04093245
- Testing
- GEM nurse, pre- and post-hospitalization medication list reconciliation, systematic discharge summaries
- Where
- Canada
- Volunteers
- 4,000 people
- Sponsor
- Laval University
Cancer
Assessment of a Multidisciplinary Team Meeting (RCP) in Geriatric Oncology
In France, cancer incidence increases over the course of life and therefore it is considered as an important pathology of the elderly. Cancers are the second leading cause of death for patients over 70 years old.
- Trial name
- EROG (NCT03662061)
- Testing
- Assessment of the follow-up of oncological and geriatric recommendations 4 months after the RCP
- Where
- 2 sites in France
- Volunteers
- 120 people
- Sponsor
- Hospices Civils de Lyon
Frailty, Critical Illness
Prevalence and Long Term Effects of Frailty in Elderly Intensive Care Patients
The primary aim is to study change of critical frailty scale (CFS) and health related quality of life (EQ-5D-5L) in a long-term follow-up of ICU survivors.
- Trial name
- SkrInt (NCT06012942)
- Where
- 5 sites in Norway
- Volunteers
- 300 people
- Sponsor
- University Hospital of North Norway
Hospital Acquired Condition, Frailty
Effect of a Multicomponent Exercise Program With Virtual Reality (MEP-VR) vs Standard Approaches on Functional and Cognitive Domains in Hospitalized Geriatric Patients: Study Protocol for a Randomized Controlled Trial.
The goal of this clinical trial is to test the effectiveness of a Multicomponent Exercise Program with Virtual Reality (MEP-VR) compared to a Multicomponent Exercise Program (MEP-only) or usual care, in terms of functional and…
- Trial name
- MEP-VR (NCT06469554)
- Testing
- MEP-only group, MEP-VR group
- Where
- Spain
- Volunteers
- 156 people
- Sponsor
- Fundacion Miguel Servet
Alzheimer Disease
Virtual Environment to Aid Cognitive Stimulation of Elderly People With Early Alzheimer's
This research was carried out with the objective of verifying the possibility of intervention through cognitive training protocols to assist in the stimulation of neurons and to delay the degradation resulting from Alzheimer's…
- Trial name
- NCT04919005
- Testing
- Virtual Environment
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Mogi das Cruzes
Risk of Falling in the Elderly
Fall Risk Assessment With an Innovative Device for Quantifying Gait and Static Balance in Geriatric Consultation
The main objective of this monocentric, non-randomized, prospective study was to evaluate the predictive capacity of a balance score based on spatio-temporal parameters of postural balance.
- Trial name
- PARACHUTE (NCT06535477)
- Testing
- Fall risk assessment
- Where
- France
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Gérond'if
Suicidal Ideation, Depression
Gamified VR Sports for Elderly Suicidal Ideation
Detailed Description: This quasi-experimental study investigates the effectiveness of a gamified sports exercise intervention delivered through virtual reality (VR) to improve mental health and life expectancy in elderly…
- Conditions
- Suicidal Ideation, Depression, Mental Health Issue
- Trial name
- VR-LIFE-SI (NCT06856083)
- Testing
- Gamified Virtual Reality Sports Exercise Program, Traditional Sports Exercise Program for Elderly Individuals with Suicidal Thoughts
- Where
- Iran
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Influenza
Study of a Pandemic Influenza Vaccine in Elderly Participants
The World Health Organisation has warned that an influenza pandemic is inevitable. The avian influenza H5N1 virus strain is one of the leading candidates to cause the next influenza pandemic.
- Trial name
- NCT00376402
- Testing
- H5N1 Pandemic Influenza Vaccine
- Where
- 2 sites in Australia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Seqirus
Aortic Valve Disease
Study on Optimal Treatment Strategy for Elderly Patients With High-risk Complex Aortic Valve Disease
Aortic valve disease (AVD) is the most common and age-related mortality in elderly patients with valvular heart disease (VHD). Although transcatheter aortic valve replacement (TAVR) has been recommended at a higher level in…
- Trial name
- NCT05044377
- Where
- China
- Volunteers
- 540 people
- Sponsor
- Yongjian Wu
Hip Fracture, Hypotension
Continuous Spinal Anesthesia With Hypobaric Bupivacaine to Preserve Hemodynamics in Elderly
The study evaluates the potential beneficial effects on hemodynamics when hypobaric bupivacaine is used instead of isobaric bupivacaine in continuous spinal anesthesia for surgical repair of hip fracture in elderly patients.
- Trial name
- NCT02428257
- Testing
- continuous spinal anesthesia, hypobaric bupivacaine, isobaric bupivacaine
- Where
- Tunisia
- Volunteers
- 120 people
- Sponsor
- Institut Kassab d'Orthopédie
Sarcopenia
Effects of Dietary Supplements on Sarcopenic Elders
Sarcopenia is defined as a syndrome characterized by decline of skeletal muscle mass and strength or an alteration in physical function.
- Trial name
- NCT03860194
- Testing
- Protison with High Protein 51(Original Flavor)
- Where
- Taiwan
- Volunteers
- 85 people
- Sponsor
- Far Eastern Memorial Hospital
Primary Insomnia
Elderly Primary Insomnia Polysomnographic Study (0928-002)(TERMINATED)
The purpose of the study is to test the safety and effectiveness of an Investigational Drug on insomnia in the elderly.
- Trial name
- NCT00094666
- Testing
- MK0928, gaboxadol / Duration of Treatment - 6 weeks
- Volunteers
- 465 people
- Sponsor
- H. Lundbeck A/S