Clinical trials: Older Adults
the Elderly, Respiratory Disorders
Effects of Pulmonary Rehabilitation in Salt Chambers on Functional Efficiency, Respiratory Parameters, and Blood Rheology in Elderly With Respiratory Diseases.
The aim of the study is to assess the impact of the rehabilitation and treatment stay at the underground Health Resort of the 'Wieliczka' Salt Mine in Wieliczka on the functional capacity, respiratory parameters, and rheological…
- Trial name
- PRSC-FERPBR (NCT06951633)
- Testing
- Subterranean, pulmonary rehabilitation
- Where
- Poland
- Volunteers
- 33 people
- Sponsor
- University School of Physical Education, Krakow, Poland
Hypertension, Pulmonary
Long-term Ambrisentan Extension Study for Pediatric Patients Who Participated in AMB112529
An open label, long term extension to Study AMB112529. All subjects may remain in the extension study for a minimum of six months.
- Trial name
- NCT01342952
- Testing
- Ambrisentan
- Where
- 22 sites in United States, Argentina and 7 more
- Volunteers
- 38 people
- Sponsor
- GlaxoSmithKline
Anticholinergic Adverse Reaction
Intervention to REduce anticholinerGic burdEN in oldER pATiEnts (REGENERATE) Aged 65 Years and Older
Medications with anticholinergic properties are frequently prescribed for several conditions in older age; for example cardiovascular drugs (e.g. digoxin, furosemide), urologicals (e.g.
- Trial name
- REGENERATE (NCT04660838)
- Testing
- ACB intervention
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Aberdeen
Pain, Blood Sampling Procedure
The Effect of a Guessing Game on Fear, Pain, and Emotional State During Blood Collection in Children Aged 6-12
The aim of this study is to evaluate the effects of a guessing game on fear, pain and emotional state during blood collection in children aged 6-12 years.
- Conditions
- Pain, Blood Sampling Procedure, Fear Anxiety
- Trial name
- NCT07299058
- Testing
- I Wonder What I Am Play
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Cognitive Dysfunction, Mild Cognitive Impairment
Effect of Dual Task Exercise on Cognitive and Physical Function in the Elderly With Mild Cognitive Impairment
The purpose of this study is to investigate the effect of the dual task exercise program on cognitive and physical function in the elderly with mild cognitive impairment.
- Trial name
- NCT05855785
- Testing
- dual task exercise, home exercise
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Seoul National University Boramae Hospital
Atrial Fibrillation New Onset
Screening for Atrial Fibrillation in Elderly Women Older Than 70 Years
Screening for Atrial Fibrillation in Elderly Women (SAFE-W) is a pilot study evaluating the prevalence of atrial fibrillation (Afib) in a rapidly aging segment of the population.
- Trial name
- SAFE-W (NCT05444335)
- Testing
- Wearable cardiac monitor -Zio patch
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Severe Aplastic Anemia, Aplastic Anaemia
A Novel Conditioning Regimen for Haplo-HSCT in Older Patients With SAA
The goal of this prospective, multicenter, single arm observational study is to evaluate the efficacy and safety of the BFCA regimen in ≥ 40 years old SAA patients undergoing haplo-HSCT.
- Conditions
- Severe Aplastic Anemia, Aplastic Anaemia, Hematopoietic Cell Transplant
- Trial name
- NCT07586735
- Testing
- BFCA conditiong regimen
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Peking University People's Hospital
Sarcopenia in Elderly, Chronic Heart Failure
Effects of Resistance Training on Sarcopenia in Older Patients With Chronic Heart Failure
The goal of study is to evaluate the effects of an eight-week machine-based resistance training program on managing sarcopenia in older outpatients with chronic heart failure (HF) at Military Hospital 175.
- Trial name
- NCT06785168
- Testing
- Machine-based Resistance Training
- Where
- 2 sites in Vietnam
- Volunteers
- 146 people
- Sponsor
- Kieu Dang Phuong Nguyen
Healthy
Health Effects of Milk Proteins in Elderly Subjects
The aim of the present study is to investigate effects of milk on body composition and muscle strength, inflammation, appetite, DNA damage/repair and PBMC whole genome transcriptomics in elderly subjects.
- Trial name
- NCT02218333
- Testing
- Milk
- Where
- Norway
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Chronic Disease
Pilot Evaluation of "KeepWell" Using a Hybrid Effectiveness-Implementation Pragmatic Randomized Controlled Trial
The burden of chronic disease is a global phenomenon, particularly amongst seniors. Aging is an expensive process. In Canada, 10% of seniors who have the most complex health needs account for 60% of the total annual health care…
- Trial name
- NCT04437238
- Testing
- KeepWell tool, Control - Usual care
- Where
- Canada
- Volunteers
- 456 people
- Sponsor
- North York General Hospital
Human Papillomavirus Infection, HPV
Human Papillomavirus in Young People Epidemiological Research 4
Anal cancer is overrepresented among gay, bisexual and other men who have sex with men (MSM), particularly those living with HIV.
- Conditions
- Human Papillomavirus Infection, HPV, HPV Infection, Anal Cancer
- Trial name
- HYPER4 (NCT05587738)
- Where
- Australia
- Volunteers
- 500 people
- Sponsor
- Monash University
Diabetes Type 1
Transition of T1DM Patients Aged Over 65 Years Into AHCL (780G) Insulin Pump
Older people with diabetes have a higher risk for cognitive impairment and for physical disability whether this may be effected by an improvement in glucose indices is unknown.
- Trial name
- 780G65+ (NCT06207838)
- Testing
- MiniMed 780G system
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Jagiellonian University
Depression
Treatment of Depression in the Elderly
The study is designed to establish the efficacy and tolerability of escitalopram in the treatment of depressive episodes of mild to moderate severity in the elderly.
- Trial name
- NCT00130455
- Testing
- escitalopram
- Where
- Denmark
- Volunteers
- 189 people
- Sponsor
- Psychiatric Hospital, Hillerod
Ageism
The Effect of Elderly Care Training Given to Nursing Students on Ageism
geism is a multidimensional term that includes different attitudes, prejudices, behaviors and actions shown to a person simply because of his or her age.
- Trial name
- NCT06488885
- Testing
- Elderly care training
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Beykent
Multimorbidity
Self-Management Program for Older Adults With Multimorbidity
Patients with multimorbidity move between multiple care settings, and so they are at high risk of receiving fragmented care leading to increased risk for avoidable illness, death, and health care costs.
- Trial name
- NCT02209285
- Testing
- Self-Management Program for Older Adults with Multimorbidity
- Where
- Canada
- Volunteers
- 59 people
- Sponsor
- McMaster University
Autism
Open Label of Clinical Trial of Sulforaphane in Children With Autism
This is an open-label, 4-month study examining the effects of Sulforaphane (SF) on behavior in children with ASD and the correlation between behavior change and urinary metabolites.
- Trial name
- NCT02654743
- Testing
- Sulforaphane
- Volunteers
- 21 people
- Sponsor
- University of California, San Francisco
Penile/Perineal /Perianal Intraepithelial Neoplasia, Anal Intraepithelial Neoplasia
A Phase III Trial to Evaluate the Efficacy, Immunogenicity and Safety of a Recombinant Human Papillomavirus 9-Valent (Types 6, 11, 16, 18, 31, 33, 45, 52, 58) Vaccine (E.Coli) in Chinese Males
This phase III clinical trial was designed to evaluate the efficacy, immunogenicity and safety of a Recombinant Human Papillomavirus 9-Valent (Types 6, 11, 16, 18, 31, 33, 45, 52, 58) Vaccine (E.Coli) manufactured by Xiamen…
- Conditions
- Penile/Perineal /Perianal Intraepithelial Neoplasia, Anal Intraepithelial Neoplasia, Penile/Perianal/Perineal Cancer, Anal Cancer
- Trial name
- NCT06866574
- Testing
- Recombinant Human Papillomavirus 9-Valent (Types 6, 11, 16, 18, 31, 33, 45, 52, 58) Vaccine (E.coli), Aluminum Adjuvant
- Where
- 4 sites in China
- Volunteers
- 9,300 people, healthy volunteers welcome
- Sponsor
- Xiamen University
Loneliness, Sleep Quality
Mindfulness for Lonely Older Adults With Emigrant Children
This study is to examine the feasibility of a proposed mindfulness-based intervention (MBI) and study methodology for future main study.
- Conditions
- Loneliness, Sleep Quality, Quality of Life, Stress
- Trial name
- NCT07711860
- Testing
- Intervention, Active Control
- Where
- Hong Kong
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hong Kong Metropolitan University
Influenza Immunization
Study to Evaluate Safety and Immunogenicity of a Pandemic Flu H5 mRNA Vaccine in Healthy Adults Aged 18 Years and Older
The purpose of this study is to evaluate a pandemic flu H5 strain messenger ribonucleic acid (mRNA) vaccine at 3 dose levels (low, medium, and high) in comparison with placebo in 276 healthy adult participants to select the…
- Trial name
- NCT06727058
- Testing
- Pandemic flu H5 mRNA vaccine
- Where
- 14 sites in United States
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
End Stage Renal Disease, Catheter Infection
AUSTrian Randomized Interventional Study on Dialysis Accesses
Patients with diagnosed end stage renal disease and indication for chronic dialysis rely on a well-functioning access for dialysis.
- Conditions
- End Stage Renal Disease, Catheter Infection, Shunt Malfunction
- Trial name
- AUSTRIA (NCT03764358)
- Testing
- Arteriovenous Fistula, Tunneled Cuffed Catheter
- Where
- Austria
- Volunteers
- 220 people
- Sponsor
- Medical University of Vienna