Clinical trials: Older Men
Prostate Carcinoma
Systemic Light Exposure in Preventing Frailty in Older Patients With Prostate Cancer on Hormonal Therapy
This pilot trial studies how well systemic light exposure works in preventing frailty in older patients with prostate cancer on hormonal therapy.
- Trial name
- NCT03661437
- Testing
- Actigraph, Questionnaire Administration, Systematic Light Exposure
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- City of Hope Medical Center
Sarcopenia, Hypogonadism
TOM: Testosterone in Older Men With Sarcopenia
The purpose of this study is to determine whether testosterone replacement in older men with low testosterone levels will increase muscle strength, improve physical performance and overall sense of well being, and reduce fatigue.
- Conditions
- Sarcopenia, Hypogonadism, Muscular Diseases
- Trial name
- NCT00240981
- Testing
- Topical testosterone gel 1% (active formulation)
- Where
- 2 sites in United States
- Volunteers
- 209 people
- Sponsor
- Boston Medical Center
Diet, Food, and Nutrition
Resistance Exercise and Hydrolyzed Collagen Supplementation
This study aimed to investigate the effect of different doses of hydrolyzed collagen (HC) with resistance exercise (RE) on whole body collagen synthesis in healthy young and older males and females.
- Trial name
- NCT05932771
- Testing
- Experimental: Consumption of three different doses of hydrolyzed collagen (HC) with reistance exercise, Experimental: Consumption of two different doses of hydrolyzed collagen (HC) with reistance exercise
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Rob Erskine
Obesity
Weight Loss and Exercise in Obese, Physically Limited, Older Women and Men
The purpose of this study is to determine the effect of weight loss and exercise on physical function, body fat and muscle mass, bone strength, and quality of life.
- Trial name
- NCT00146107
- Testing
- Diet, Exercise, Weight Loss and Exercise
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Washington University School of Medicine
Healthy
Metabolic Availability of Methionine From Mung Beans in Healthy Adults
The research study is being done so we can determine the quality of the protein present in Mung beans. Amino acids are the building blocks of protein and protein quality is determined by the amount of amino acids present and by…
- Trial name
- NCT03674723
- Testing
- Dietary Intakes
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Older Men and Women With High Fall Risk
A Balanced Assessment and Training Protocol (BATP) to Address Balance Disorders in Older and Neurologically Disabled Veterans
Falls are by far the leading cause of accidental injury and death in older adults. The Veteran population is more severely affected by falls since it is significantly older than the overall population (45% over 65 years of age…
- Trial name
- BATP (NCT04359888)
- Testing
- Multi-Modality Balance Intervention, Balanced Reach Training (BRT)
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Prostate Cancer, Physical Function
RESIST-ADT (Androgen Deprivation Therapy)
The overall goal of this study is to determine if implementing structured exercises prevent decline in muscle mass, muscle strength and physical function in men with prostate cancer undergoing androgen deprivation therapy (ADT).
- Trial name
- NCT04485767
- Testing
- Progressive Resistance Training Exercise, Flexibility and Balance Exercise
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- Dana-Farber Cancer Institute
Medical Male Circumcision
An Implementation Science Study Investigating Profiles of Men Interested in MMC
There are both supply and demand gaps in our understanding of how best to implement MMC services. In terms of supply of MMC services, there is a need to better understand what the best way is of efficiently accessing mature…
- Trial name
- Imbizo (NCT02352961)
- Testing
- Exclusive Intervention Strategy
- Where
- South Africa
- Volunteers
- 2,817 people, healthy volunteers welcome
- Sponsor
- The Aurum Institute NPC
Lower Urinary Tract Symptoms
Study to Evaluate Efficacy and Safety of NDS-446 in Men With Lower Urinary Tract Symptoms (LUTS)
Prospective, Randomized, Double-Blind, Placebo Controlled clinical trial to study the efficacy and the safety of NDS-446 (500 mg/cap) in Men 45 years of age or older with moderate to severe lower urinary tract symptoms (LUTS)
- Trial name
- NCT02808013
- Testing
- NDS-446
- Volunteers
- 116 people
- Sponsor
- Naturex-Dbs
Sarcopenia
Anabolic and Inflammatory Responses to Short-Term Testosterone Administration in Older Men
Skeletal muscle loss is a common consequence of aging and in some individuals reaches a level that compromises health and quality of life.
- Trial name
- NCT00957801
- Testing
- Testosterone injection, Testosterone gel, Medrol
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Prostate Cancer
Effect Of Risedronate On Bone Mass In Older Men Receiving Neoadjuvant Therapy For Prostate Cancer
Men treated with neoadjuvant luteinizing hormone-releasing hormone (LHRH)-agonists such as leuprolide and goserelin for prostate cancer will become hypogonadal due to hormonal suppression and demonstrate increased bone turnover…
- Trial name
- NCT00859027
- Testing
- risedronate
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- UConn Health
Sarcopenia, Obesity
Citrulline Supplementation Combined With Exercise: Effect on Muscle Function in Elderly People (CITEX Study)
The main objective of this study is to determine if oral supplementation of Citrulline, when combined with HIIT, can produce significant changes in body composition, muscle quality, muscle metabolism and functional capacity in…
- Trial name
- CITEX (NCT02417428)
- Testing
- Citrulline, Exercise, without exercise
- Where
- Canada
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Université du Québec a Montréal
Immune Response, Inflammation
Effect of Blueberries on Immunity
This research study will test the effects of Blueberries on immune functions in overweight older men and postmenopausal women
- Trial name
- Blueberry (NCT05534893)
- Testing
- Blueberry powder group
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Sarcopenia
The Effects of Long Term Cyclic Testosterone Administration on Muscle Function and Bone in Older Men
The general hypothesis is that administration of testosterone to healthy, older men for 52 weeks (1 year) following a cycle of 4 weeks of testosterone administration and 4 weeks without testosterone (i.e., monthly cycled regimen)…
- Trial name
- NCT01417364
- Testing
- Testosterone enanthate
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Energy Metabolism
Muscle Energy Metabolism and Metabolic Flexibility in Older Men and Women
This study will explore differences in energy metabolism and metabolic flexibility under various conditions in older men and women.
- Trial name
- NCT03701867
- Testing
- Metabolic Flexibility Tests
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Sarcopenia, Prostate Cancer
Identifying Fundamental Mechanisms of Skeletal Muscle Ageing in Older Men Undergoing Androgen Deprivation Therapy: a Feasibility Study
To find out whether it is possible to run a study looking at the underlying markers of ageing in muscle quality and quantity in men receiving Androgen Deprivation Therapy for prostate cancer treatment.
- Conditions
- Sarcopenia, Prostate Cancer, Muscle Atrophy, Androgen Deprivation Therapy
- Trial name
- MASS-ADT (NCT07134439)
- Volunteers
- 20 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Brain Vascular Function, Cerebral Blood Flow
Effects of Peanut Consumption on Brain Function
Impaired brain vascular function precedes the development of reduced cognitive performance, while brain insulin-resistance is also associated with cognitive decline.
- Conditions
- Brain Vascular Function, Cerebral Blood Flow, Brain Insulin Sensitivity, Cognitive Performance
- Trial name
- NCT05724654
- Testing
- Skin roasted peanuts
- Where
- Netherlands
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Brain Insulin Sensitivity, Brain Vascular Function
Effects of Ketone Monoesters on Brain Function
Disturbances in brain insulin-sensitivity are not only observed in obesity and type 2 diabetes (T2D), but also during brain aging and in dementia.
- Conditions
- Brain Insulin Sensitivity, Brain Vascular Function, Cerebral Blood Flow, Cognitive Performance
- Trial name
- NCT06395051
- Testing
- Ketone Monoester
- Where
- Netherlands
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Muscular Atrophy
Two Weeks of Reduced Activity and Skeletal Muscle Health in Older Men
Muscle size declines at around 0.5-1% per year after 50 years of age, with muscle strength declining up to twice as fast as muscle size.
- Trial name
- NCT02495727
- Testing
- Step-reduction, Pre-training, Exercise snacking
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Bath
Low Testosterone
Effects of TAK-448 in Middle-aged and Older Men With Low Testosterone
The purpose of this study is to evaluate the effects on serum testosterone (ST) after 6 weeks of subcutaneous (SC) administration of different doses and dosing frequencies of TAK-448 to middle-aged and older men with low ST…
- Trial name
- NCT02381288
- Testing
- TAK-448
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Takeda