Clinical trials: Older People, open to volunteers
To Develop, Test, Implement and Evaluate a Model for Person-centred Care for Older People at Two Academic Residential Care Facilities
ProFoUND PCC= A Program For a Userbased Nursing Development in Person-Centered Care, is a Project That Aims to Develop, Test and Evaluate Effects of a Co-created Intervention to Increase Person-centred Care in Residential Care Settings for Older People.
The aim of this project is to develop, test and evaluate effects of a co-created intervention to increase person-centred care in residential care settings for older people.
- Trial name
- ProFoUND PCC (NCT07921953)
- Testing
- A program for a userbased nursing development in person-centred care
- Where
- Sweden
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Mälardalen University
Older People
Dose-Response and Phase-Specific Effects of Graded Cognitive Load on Functional Mobility in Older Adults: A Kinematic Analysis
This study will be conducted to investigate the effect of dose-response and phase-specific effects of Graded Cognitive Load affect on functional mobility in Older Adults
- Trial name
- CL (NCT07814053)
- Testing
- Dual-Task Cognitive Loading Protocol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Older People, Pain
Exploring the Acute and Dynamic Relationships Between Movement and Pain in Older Adults With Musculoskeletal Pain
The purpose of this research study is to evaluate the effect of brief bouts of intermittent walking on bodily pain, pain during movement, and how the body adapts to musculoskeletal pain in older adults.
- Trial name
- NCT06886906
- Testing
- Intermittent light walking, uninterrupted sitting
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Indiana University
Older Adults (65 Years and Older), Polypharmacy (People Under Treatment With 5 or More Drugs)
Impact of Pharmacotherapy Optimization in Polymedicated Lebanese Older Adults in Primary Health Care Centers
Why are the researchers doing this study? Many older adults take five or more medicines every day. Some of these medicines may no longer help them. Some may even cause harm, such as falls, confusion or tiredness.
- Conditions
- Older Adults (65 Years and Older), Polypharmacy (People Under Treatment With 5 or More Drugs), Primary Health Care, Social Determinants of Health (SDOH)
- Trial name
- PHARMACT-PHC (NCT07866677)
- Testing
- Structured pharmacotherapy optimization, Usual Care
- Where
- Lebanon
- Volunteers
- 452 people
- Sponsor
- National Institute of Public Health, Clinical Epidemiology, and Toxicology-Lebanon (INSPECT-LB)
Older Adults (65 Years and Older), Living Alone
Home-based Monitoring & Enabled Medication Independence With New Digital Tools
This clinical trial is studying an online tool that may help older adults safely manage their medications at home. The study focuses on older adults who live alone and have memory concerns or mild changes in thinking.
- Conditions
- Older Adults (65 Years and Older), Living Alone, Mild Cognitive Decline, Polypharmacy (People Under Treatment With 5 or More Drugs)
- Trial name
- HOME-MIND (NCT07659548)
- Testing
- HOME-MIND
- Volunteers
- 60 people
- Sponsor
- University of Michigan
Locally Advanced Rectal Cancer, Older People
Efficacy and Safety of Conventional Neoadjuvant Therapy Versus Total Neoadjuvant Therapy in Older Patients With Locally Advanced Rectal Cancer
The SHAPERS study is a multicentre, open-label, randomised, pragmatic clinical trial, comparing standard-of-care neoadjuvant treatment options for older (i.e., ≥70 years) subjects with high-risk stage II and stage III rectal…
- Trial name
- SHAPERS (NCT06052332)
- Testing
- Short course radiotherapy, Adjuvant chemotherapy (optional), Total mesorectal excision
- Where
- 19 sites in Belgium
- Volunteers
- 230 people
- Sponsor
- Jules Bordet Institute
Older People
The FINGER Model - Preventing Cognitive Decline and Promoting Health of Older People.
Cognitive impairment and dementia can cause considerable suffering, both for the person affected and for next of kin. They also pose major challenges for health and social care.
- Trial name
- NCT07661472
- Testing
- FINGER model
- Where
- Sweden
- Volunteers
- 180 people
- Sponsor
- University of Gavle
Healthy Older Adults, Postural Balance
INDIVIDUALIZED DUAL-TASK TRAINING FOR BALANCE AND MOBILITY IN OLDER ADULTS
The goal of this clinical trial is to prevent functional decline and improve mobility in healthy older adults aged 65 and over. The main questions it aims to answer are: What is the effect of individualized dual-task training on…
- Conditions
- Healthy Older Adults, Postural Balance, Dual Task Exercises in Elderly People, Dual Task Cost
- Trial name
- NCT07448961
- Testing
- Individualized Dual-Task Training, Standardized Dual-Task Training, Single-Task Motor Training
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Sezen Karaborklu Argut
Person-Centred Care, Well Being
Elderly Care in Transition - Perspectives of the Elderly and the Staff
Elderly care in Sweden faces several significant challenges. The number of older people is increasing at the same time as there are fewer of working age.
- Conditions
- Person-Centred Care, Well Being, Health, Environment
- Trial name
- NCT07508878
- Testing
- Academic nursing homes
- Volunteers
- 600 people
- Sponsor
- University of Gavle
Older People With Home Care, Staff Working With Older People in Home Care
Elderly Care in Transition - the Older Persons' and the Staff's Perspective
Elderly care has and is facing several challenges with an increasing number of older people and fewer of working age. Strengthening the positive aspects will be central and creating good conditions for older people and staff for…
- Trial name
- NCT07504159
- Where
- Sweden
- Volunteers
- 1,980 people
- Sponsor
- University of Gavle
Hemodialysis, Hemodiafiltration
Hemodiafiltration Versus Hemodialysis in Older People
This study will compare the impact of two hemodialysis techniques on fatigue and post-dialysis recovery time in patients aged 85 years and older. These two techniques are high-flux hemodialysis (HD) and hemodiafiltration (HDF).
- Conditions
- Hemodialysis, Hemodiafiltration, Fatigue Symptom, Quality of Life of Patients
- Trial name
- HD-OLDER (NCT07278973)
- Testing
- High-flux hemodialysis, Hemodiafiltration
- Where
- 4 sites in France
- Volunteers
- 62 people
- Sponsor
- AUB Santé
Amputation, Functional Limitation
Impact Evaluation of Breizh Fabribus Intervention for Personalized Assistive Technology Creation or Adaptation
In France, more than 14 million individuals report severe functional limitations, and nearly 5 million struggle with essential daily activities.
- Conditions
- Amputation, Functional Limitation, Autonomy of Older People, Handicaps Physical
- Trial name
- BFB-IMPACT (NCT07314099)
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fondation Ildys
Insomnia Chronic, Older People
Efficacy of Trazodone to Treat Insomnia in Older Adults (TRADITION Study)
This study aims to evaluate how effective trazodone is in treating insomnia in adults aged 65 years and older. The main question it aims to answer is : Is trazodone more effective than a placebo in reducing the severity of…
- Conditions
- Insomnia Chronic, Older People, Drug Therapy
- Trial name
- TRADITION (NCT06983080)
- Testing
- Trazodone 25 mg
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Gut -Microbiota, Older People
Probiotics and Active Aging: Enhancing Gut Health
The general objective of this clinical trial is to assess the physical fitness and gut microbiota of older adults, thereby highlighting the importance of focusing on health maintenance.
- Conditions
- Gut -Microbiota, Older People, Physical Activity, Physical Fitness
- Trial name
- PAAEGH (NCT07033637)
- Testing
- Dietary Supplement, Structured Physical Activity Program
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Jose Luis Felipe
Non-small Cell Lung Cancer, Older People
Carbon Ion Radiotherapy for Locally Advanced Lung Cancer in Elderly Patients
To observe the effect and toxicity of carbon ion radiotherapy on local advanced non-small cell lung cancer over 75 years old patients. Systemic therapy could be targeted therapy, chemotherapy or immunotherapy.
- Conditions
- Non-small Cell Lung Cancer, Older People, Carbon Ion Radiotherapy, Radiotherapy Side Effect
- Trial name
- NCT06311981
- Testing
- carbon ion radiotherapy, targeted therapy, single regimen chemotherapy in sequence with radiotherapy
- Where
- China
- Volunteers
- 29 people
- Sponsor
- Jian Chen
Mild Cognitive Impairment, Older People
A Socio-Technological Intervention in Community-Based Healthcare for Individuals With Mild Cognitive Impairment (DHEAL-COM-MCI)
The objectives of the intervention are to counteract the progression of cognitive decline, enhance the intrinsic abilities of users and support the well-being of elderly people with mild cognitive impairment (MCI) through a…
- Trial name
- DHEAL-COM-MCI (NCT06984367)
- Testing
- socio-technical intervention, Usual care
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
Osteoporosis, Older People
Tele-Rehabilitation Intervention in Community-Based Healthcare for Patients With Osteoporosis (DHEAL-COM-OP)
The DHEAL-COM-OP study is characterized as a feasibility study. The general objective is to evaluate the improvement in the physical performance of patients with osteoporosis detected through the Performance-Oriented Mobility…
- Trial name
- DHEAL-COM-OP (NCT06984380)
- Testing
- Telerehabilitation, Usual care
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
Parkinson Disease, Older People
Tele-Rehabilitation Intervention in Community-Based Healthcare for Patients With Parkinson's Disease (DHEAL-COM-PD)
The study aims to measure the improvement in functional capacity in a group of elderly people suffering from early-stage Parkinson's disease (Hoehn \& Yahr scale 1-3), following a telerehabilitation intervention integrated with…
- Trial name
- DHEAL-COM-PD (NCT06984393)
- Testing
- home tele-rehabilitation, Usual care
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
Critical Illness, Geriatric Assessment
Geriatric Assessment at Discharge From the Intensive Care Unit in Patients Aged 75 Years and Older: a Feasibility Study
The number of patients aged over 75 continues to grow, and, according to INSEE, will represent almost 10% of the French population in 2021, an increase of 2.4 points since 2000.
- Conditions
- Critical Illness, Geriatric Assessment, Older People, Frailty
- Trial name
- PreGEDI (NCT06513130)
- Testing
- Geriatric assessment in the 7 days following ICU discharge., No geriatric assessment in the 7 days following ICU discharge.
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Strasbourg, France
Older People
Underprescribing in Geriatric Patients: a Prevalence Study and Analysis of Factors Contributing to Potential Prescription Omissions (Under-PRES)
This observational study will determine the prevalence of underprescription in a cohort of elderly patients, recruited at the time of an outpatient geriatric visit, or hospitalized, upon admission to a geriatric ward.
- Trial name
- Under-PRES (NCT06904638)
- Where
- 2 sites in Italy
- Volunteers
- 374 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani