Clinical trials: Older Women
Sarcopenia
Investigation of the Relationship Between Sarcopenia and Balance, Fear of Falling and Fall Risk in Older Female Patients
This study (study type: cross-sectional) aims to investigate the relationship of sarcopenia level with balance, fear of falling and risk of falling in the elderly female population.
- Trial name
- NCT06277193
- Testing
- valuation of balance status, fear of falling and risk of falling in patients non-sarcopenia., Evaluation of balance status, fear of falling and risk of falling in patients with probable sarcopenia., Evaluation of balance status, fear of falling and risk of falling in patients with sarcopenia.
- Where
- Turkey (Türkiye)
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Konya Beyhekim Training and Research Hospital
Chronic Kidney Diseases
Geriatric Assessment for Older Kidney Transplantation Candidates
Geriatric assessment is now widely used to decide whether older patients with chronic kidney disease should be put on the kidney transplantation waiting list.
- Trial name
- NCT05395247
- Testing
- Geriatric assessment
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Caen
Back Pain, Headache
Influence of Dalcroze Eurhythmics on Pains in Older Women
In this study, we attempted to answer the question of whether participation in a 12-week rhythmic exercise program using the Dalcroze method affects the level of intensity of pain experienced by women over the age of 65.
- Conditions
- Back Pain, Headache, Leg Pain
- Trial name
- NCT06264102
- Testing
- Physical exercise program
- Where
- Poland
- Volunteers
- 61 people
- Sponsor
- Poznan University of Physical Education
Kidney Failure, Chronic
Advance Care Planning With Older Patients Who Have End-stage Kidney Disease
This study will test the feasibility of carrying out a randomised controlled trial, incorporating a mixed methods process evaluation, to evaluate advance care planning with older patients who have end-stage kidney disease.
- Trial name
- ACREDiT (NCT02631200)
- Testing
- Advance care plan
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Queen's University, Belfast
Resilience, Psychological
The BRIgHT Program: Building Resilience in HIV Together
This is the second phase of a two-part study. In the first phase (Protocol ID: R34AT009170), the investigators refined and piloted the Relaxation Response Resiliency (3RP) intervention for women age 50 and over who are living…
- Trial name
- NCT03673098
- Testing
- Adapted 3RP
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Massachusetts General Hospital
Metastatic Non Small Cell Lung Cancer, Recurrent Non Small Cell Lung Cancer
Etirinotecan Pegol (NKTR-102) in NSCLC
This Phase 2 study is designed to characterize the objective response rate (defined as complete response (CR) and partial response (PR)) of Etirinotecan pegol administered to subjects with metastatic and recurrent NSCLC after…
- Trial name
- NCT01773109
- Testing
- Etirinotecan pegol (NKTR-102)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Healthy Aging
Preventing Chronic Disease: ActuaYa
The purpose of the study is to help older Hispanic women to increase physical activity, reach a healthy body weight, increase self-esteem and mood and increase knowledge about chronic diseases such as hypertension, diabetes, and…
- Trial name
- NCT04088552
- Testing
- Go4Life-Physical Activity/Exercise Program "Workout to Go" 5, ActuaYa Educational Sessions
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Miami
Dementia, Chronic Disease
Project to Improve Communication About Serious Illness--Hospital Study: Pragmatic Trial (Trial 1)
The objective of this protocol is to test the effectiveness of a Jumpstart intervention on patient-centered outcomes for patients with chronic illness by ensuring that they receive care that is concordant with their goals over…
- Conditions
- Dementia, Chronic Disease, Neoplasm Metastasis, Lung Neoplasm
- Trial name
- PICSI-H (NCT04281784)
- Testing
- EHR-based Clinician Jumpstart
- Where
- 3 sites in United States
- Volunteers
- 2,512 people
- Sponsor
- University of Washington
Osteoporosis
Aquatic Verses Land Exercise to Decrease Fall Risk
Compare the effect of aquatic,land and no exercise on fall risk factors in women diagnosed with osteoporosis
- Trial name
- NCT00227071
- Testing
- exercise
- Where
- Canada
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Urinary Incontinence, Falls, Accidental
Continence Across Continents to Upend Stigma and Dependency
To determine whether women exposed to the continence promotion intervention will report improved urinary symptoms and quality of life, and lower incontinence-related stigma and falls than women who receive a control intervention…
- Conditions
- Urinary Incontinence, Falls, Accidental, Quality of Life, Stigma
- Trial name
- CACTUS-D (NCT01858493)
- Testing
- Continence promotion group education workshop
- Where
- 4 sites in Canada, France and 1 more
- Volunteers
- 910 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Obesity, Overweight (BMI > 25)
CHANGES IN SLEEP QUALITY AND BODY COMPOSITION FOLLOWING A MULTIMODAL LIFESTYLE INTERVENTION IN OLDER WOMEN
This single-arm pilot study evaluated changes in sleep quality, body composition, biochemical parameters, physical activity, and psychological well-being following a 12-week multimodal lifestyle intervention in overweight and…
- Conditions
- Obesity, Overweight (BMI > 25), Sleep Quality, Body Composition
- Trial name
- NCT07740902
- Testing
- Multimodal Lifestyle Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Saglik Bilimleri Universitesi
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
Dose-Reduced Docetaxel With Cyclophosphamide for the Treatment of Vulnerable Older Women With Stage I-III HER2 Negative Breast Cancer, the DOROTHY Trial
This phase II trial tests how well dose-reduced docetaxel combined with cyclophosphamide works in treating older women with early stage (stage I-III) HER2 negative breast cancer vulnerable to toxicity.
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, HER2-Negative Breast Carcinoma
- Trial name
- NCT06042569
- Testing
- Cyclophosphamide, Docetaxel, Medical Chart Review
- Where
- 3 sites in United States
- Volunteers
- 174 people
- Sponsor
- City of Hope Medical Center
SARS-CoV-2 Infection, COVID-19
To Evaluate the Safety, Tolerability, and Immunogenicity of BNT162b2 Against COVID-19 in Healthy Pregnant Women 18 Years of Age and Older
Results will be submitted, however please note that data are not yet available for all serology outcome measures. This will be a Phase 2/3, randomized, placebo-controlled, observer-blind study evaluating the safety, tolerability…
- Conditions
- SARS-CoV-2 Infection, COVID-19, Maternal Immunization
- Trial name
- NCT04754594
- Testing
- BNT162b2
- Where
- 90 sites in United States, Brazil and 3 more
- Volunteers
- 726 people, healthy volunteers welcome
- Sponsor
- BioNTech SE
Breast Cancer, Colorectal Cancer
Adapting Multiple Behavior Interventions That Effectively Improve Cancer Survivor Health Cancer Survivor Health
This research study will test the efficacy of interactive, web-based interventions that improve diet, physical activity and weight management changes among early stage survivors of breast, prostate, colorectal, endometrial…
- Conditions
- Breast Cancer, Colorectal Cancer, Endometrial Cancer, Kidney Cancer
- Trial name
- AMPLIFY (NCT04000880)
- Testing
- Adapting MultiPLe Behavior Interventions That eFfectively Improve (AMPLIFI) Cancer Survivor Health, Diet-Exercise, Exercise-Diet
- Where
- 2 sites in United States
- Volunteers
- 603 people
- Sponsor
- University of Alabama at Birmingham
Urinary Incontinence (UI)
Effectiveness of Chinese Herbal Medicine for Older Adults With Urinary Incontinence
This study aims to evaluate the effectiveness and safety of Chinese herbal medicine in improving urinary incontinence symptoms among older adults.
- Trial name
- NCT07637175
- Testing
- Chinese Herbal Medicine (CHM) supplement
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Kwantlen Polytechnic University
Cognitive Disorders, Delirium
The Impact of Ketamine on Postoperative Cognitive Dysfunction, Delirium, and Renal Dysfunction
Ketamine is a commonly used anesthetic medication which is used for induction of anesthesia as well as as an analgesic. It has been shown to have anti-inflammatory properties which may decrease post-operative complications…
- Conditions
- Cognitive Disorders, Delirium, Acute Kidney Injury
- Trial name
- NCT02554253
- Testing
- Ketamine, Propofol
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Mayo Clinic
Older Adults, Reduced Physical Activity
Step-reduction in Older Men and Women
This study investigates the effects of two weeks of reduced daily ambulation and a subsequent return to normal physical activity on metabolic health of older adults.
- Trial name
- CDA-SR (NCT03039556)
- Testing
- Normal Daily Steps, Step-Reduction, Return to Normal Daily Steps
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- McMaster University
Breast Cancer
Capecitabine and Vinorelbine in Treating Older Women Who Have Metastatic Breast Cancer With or Without Bone Involvement
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00003902
- Testing
- capecitabine, vinorelbine tartrate
- Where
- Switzerland
- Volunteers
- 110 people
- Sponsor
- Swiss Cancer Institute
Postexercise Hypotension
Post-Exercise Hypotension After Water Exercise
Hypertension is the most prevalent cardiovascular disease risk factor among individuals 60 years of age and older. Hypertension can be prevented and modified with lifestyle interventions that include regular exercise.
- Trial name
- NCT03112070
- Testing
- Water aerobic exercise session (WATER)
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Urinary Bladder, Overactive, Urinary Incontinence
Comparative Effectiveness of Initial OAB Treatment Options Among Older Women at High Risk of Falls
The goal of this study is to conduct a randomized pilot multi-arm clinical trial comparing a standard course of physical therapist provided pelvic floor muscle training (PFMT) to pharmacologic therapy for the treatment of urgency…
- Conditions
- Urinary Bladder, Overactive, Urinary Incontinence, Accidental Falls
- Trial name
- NCT05880862
- Testing
- Pelvic Floor Muscle Training, Mirabegron, Trospium Chloride
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- The University of Texas Medical Branch, Galveston