Clinical trials: Older Women
Breast Cancer, Colorectal Cancer
Adapting Multiple Behavior Interventions That Effectively Improve Cancer Survivor Health Cancer Survivor Health
This research study will test the efficacy of interactive, web-based interventions that improve diet, physical activity and weight management changes among early stage survivors of breast, prostate, colorectal, endometrial…
- Conditions
- Breast Cancer, Colorectal Cancer, Endometrial Cancer, Kidney Cancer
- Trial name
- AMPLIFY (NCT04000880)
- Testing
- Adapting MultiPLe Behavior Interventions That eFfectively Improve (AMPLIFI) Cancer Survivor Health, Diet-Exercise, Exercise-Diet
- Where
- 2 sites in United States
- Volunteers
- 603 people
- Sponsor
- University of Alabama at Birmingham
Respiratory Syncytial Virus
A Dose Escalation Study to Evaluate Safety, Reactogenicity, and Immunogenicity of mRNA-1345 in Healthy Adults and in Children Who Are Respiratory Syncytial Virus (RSV)-Seropositive
The primary objectives of this study are to evaluate the tolerability and reactogenicity of a single injection of up to 5 dose levels of mRNA-1345 in younger adults, women of child-bearing potential, and older adults including…
- Trial name
- NCT04528719
- Testing
- mRNA-1345
- Where
- 31 sites in United States
- Volunteers
- 651 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
Breast Cancer
Performance of MammoAlert™, Point of Care System, for the Screening of Breast Cancer in Women 18 Years of Age or Older
POC Medical Systems has developed a Point of Care system for the screening of breast cancer in the general population. Via a proprietary algorithm, the MammoAlert™ is expected to determine breast cancer's risk level for a subject…
- Trial name
- NCT03243877
- Testing
- MammoAlert Screening Test
- Where
- 7 sites in India
- Volunteers
- 2,458 people
- Sponsor
- POC Medical Systems, Inc.
Age Related Muscle Loss
Assessment of Physical Performance With A Supplementation Containing HMB in a Sample of Old Women in Good Health
The purpose of this study is to determine whether a supplementation containing β-Hydroxy-β-methylbutyrate is effective in the treatment of age-related muscle loss in a group of older women compared to a non interventional group
- Trial name
- HMB (NCT02118181)
- Testing
- HMB
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Padova
Urinary Incontinence
Briefs With Tapes Versus Pull Ups for Urinary Incontinence in Older People With Mild to Moderate Dementia (CUPID)
Urinary incontinence is a common health problem that significantly affects the quality of life of older people. The risk of urinary incontinence is increased in people living with dementia.
- Trial name
- CUPID (NCT04290403)
- Testing
- Pull Ups, Styled Briefs with tapes
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of Alberta
Cachexia
Study to Evaluate the Safety and Efficacy of 13 Weeks of the Selective Androgen Receptor Modulator (SARM) GSK2881078 in Chronic Obstructive Pulmonary Disease (COPD)
Impaired physical function and muscle dysfunction are a major consequence of COPD, which may be associated with increased mortality, poor quality of life and increased health care use.
- Trial name
- NCT03359473
- Testing
- GSK2881078
- Where
- 11 sites in United States, Germany and 1 more
- Volunteers
- 97 people
- Sponsor
- GlaxoSmithKline
Physical Inactivity
Testing Multi-Level Remote Physical Activity Interventions in a National Sample of Older Women: The WHISH EnCore Trial
While older women are disproportionately affected by chronic diseases and conditions associated with aging, including both physical and cognitive impairments, that can be alleviated or delayed by regular physical activity, few…
- Trial name
- WHISH EnCore (NCT05566873)
- Testing
- PA Education plus human and planetary health information, PA Education plus Our Voice citizen science
- Where
- United States
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Stanford University
Breast Cancer, Estrogen Receptor Positive Breast Cancer
A Breast Cancer Treatment Decision Aid for Women Aged 70 and Older
The purpose of this research study is to evaluate a decision aid to help women aged 70 and older decide on treatment for their breast cancer.
- Conditions
- Breast Cancer, Estrogen Receptor Positive Breast Cancer, Node-negative Breast Cancer, Human Epidermal Growth Factor 2 Negative Carcinoma of Breast
- Trial name
- NCT02823262
- Testing
- Breast Cancer Treatment Decision Aid for women 70+, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- Beth Israel Deaconess Medical Center
Cognitive Decline, Cardiovascular Diseases
Lifestyle Physical Activity and Cognitive Training Interventions
Older women with cardiovascular disease (CVD) are at greater risk for memory loss, an important public health issue due to the negative effects to quality of life and health care costs.
- Conditions
- Cognitive Decline, Cardiovascular Diseases, Cognitive Dysfunction, Cognitive Impairment
- Trial name
- MindMoves (NCT04556305)
- Testing
- Mind, Move
- Where
- United States
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Non-ovarian Gynecological Cancers
Radiation Adherence/Toxicity in Patients With Non-Ovarian Gynecological Cancers
The purpose of this study is to investigate the association between the Independent Activities of Daily Living (I-ADL) component of the Comprehensive Geriatric Assessment (CGA) and poor tolerance to radiation treatment in older…
- Trial name
- NCT02003430
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Healthy Older Adults
Resistance Training and Post-exercise Blood Pressure in Normotensive Older Women
The purpose of the present study was to analyze the effect of 12 weeks of resistance training on post-exercise blood pressure (BP) and to to correlate the acute and chronic decrease in blood pressure (BP) following resistance…
- Trial name
- NCT02346981
- Testing
- Resistance training
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Breast Cancer, Cervical Cancer
Dosing Physical Activity Among Older Cancer Survivors Who Experience Chronic Pain: a Micro-randomized Trial
The purpose of this study is to assess the best time to deliver a message to increase physical activity and how often participants will experience a pain episode in the 24 hours following their receipt of a message to increase…
- Conditions
- Breast Cancer, Cervical Cancer, Bladder Cancer, Colorectal Cancer
- Trial name
- NCT07227077
- Testing
- Physical Activity Promotion Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Medical College of Wisconsin
Older People
Multicomponent Training Combined With Multi-professional Intervention Health Status in Hypertensive and Normotensive Older Women
Objective: The objective of this study was to analyze the effects of multicomponent training (MCT) combined with multidisciplinary intervention (nutritional and psychoeducation) on body composition, biochemical markers, and…
- Trial name
- NCT07152158
- Testing
- multicomponent training combined with multi-professional intervention
- Where
- Chile
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Universidad Católica del Maule
Chronic Kidney Diseases
Geriatric Assessment for Older Kidney Transplantation Candidates
Geriatric assessment is now widely used to decide whether older patients with chronic kidney disease should be put on the kidney transplantation waiting list.
- Trial name
- NCT05395247
- Testing
- Geriatric assessment
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Caen
Aging, Inspiratory Muscle Weakness
Effect of Inspiratory Muscle Training on Diaphragm Muscle Thickness, Fatty Liver Density and Aerobic Capacity in Elderly Men: A Randomized Controlled Trial
This randomized controlled trial aims to investigate the effects of a 4-week inspiratory muscle training (IMT) program on diaphragm muscle thickness, fatty liver density, functional capacity, and quality of life in elderly men…
- Conditions
- Aging, Inspiratory Muscle Weakness, Fatty Liver, Reduced Functional Capacity
- Trial name
- IMT AND ELDERL (NCT07193082)
- Testing
- Experimental Inspiratory Muscle Training (IMT Group), Control Group: No inspiratory muscle training.
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Coronavirus Disease (COVID-19)
A Single Heterologous Booster Vaccination Study of TAK-019 in Healthy Japanese Adults (COVID-19)
TAK-019 is a vaccine in development to protect people against Covid-19. The main aims of the study are to learn if TAK-019 can protect people from Covid-19 and to check for side effects from TAK-019 for participants who will…
- Trial name
- NCT05299359
- Testing
- TAK-019
- Where
- 2 sites in Japan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Takeda
Pain, Chronic
Physical Activity and Percussive Massage Therapy for Reducing Pain in Older Women
Over 60% of women aged 65 and older suffer from pain, yet this group is underrepresented in research. Physical activity and percussive massage therapy may help manage pain, but both require consistent engagement, making long-term…
- Trial name
- MAPAP (NCT07056335)
- Testing
- Self-monitoring, Physical activity and percussive massage therapy education, Percussive massage therapy
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Pain, Acute
Assessment of Pain in Newborns and Older Infants (Infant Pain Assessment Study =
Pain assessments in non-verbal, critically ill infants represent an important clinical challenge. Older children or adults can easily express their pain, but infants lack that capability.
- Trial name
- iPAS) (NCT03330496)
- Testing
- Pain Measurement
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Stanford University
Osteoporosis
Selenium for Musculoskeletal Health
This research aims to determine whether selenium supplements improve bone and muscle health in older women at risk of osteoporosis (low bone density or weak bones) and fracture (broken bones).
- Trial name
- NCT02832648
- Testing
- selenase (selenium)
- Where
- United Kingdom
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
UTI - Urinary Tract Infection
Urine Collection and Novel UTI Biomarkers in Children and Older Adults
Suspected urinary tract infection (UTI) is a common driver of antibiotic prescribing and hospital admission, yet accurate diagnosis remains challenging.
- Trial name
- COLLECT-UTI (NCT07766278)
- Where
- United Kingdom
- Volunteers
- 230 people
- Sponsor
- Queen's University, Belfast