Clinical trials: Older Women
Breast Cancer
Longitudinal Impact of Adjuvant Chemotherapy on Functional Status, Comorbidity and Quality of Life
The goal of this study is to increase our understanding of the adjuvant chemotherapy experience in older and younger adults by prospectively describing the longitudinal trajectory of functional status, comorbidity, and quality of…
- Trial name
- NCT01030250
- Where
- United States
- Volunteers
- 238 people
- Sponsor
- City of Hope Medical Center
Kidney Cancer, Renal Cell Cancer
Cabozantinib and Nivolumab Among Older Patients With Renal Cell Carcinoma
The goal of the study is to describe real-life use and exposition to nivolumab-cabozantinib among older patients with metastatic clear-cell renal cell cancer
- Trial name
- CABOLD (NCT06934057)
- Testing
- Nivolumab, Cabozantinib
- Where
- 7 sites in France
- Volunteers
- 50 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Advanced Cancer
Living With Hope Program for Rural Women Caregivers
Family caregivers of terminally ill persons describe hope as inner strength that will help them continue caregiving. Our research team has developed and pilot tested a Living with Hope Program (LWHP) for caregivers of family…
- Trial name
- LWH (NCT01081301)
- Testing
- Living with Hope Program
- Where
- 2 sites in Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Breast Cancer
Doxorubicin Hydrochloride Liposome as First-Line Therapy in Treating Older Women With Metastatic Breast Cancer
RATIONALE: Drugs used in chemotherapy, such as doxorubicin hydrochloride liposome, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00960336
- Testing
- pegylated liposomal doxorubicin hydrochloride
- Where
- France
- Volunteers
- 59 people
- Sponsor
- ARCAGY/ GINECO GROUP
Sarcopenia, Collagen Degeneration
Effects of Whey Protein Supplementation Collagen Associated to Resistance Training in Older Woman
The main purpose of the present study was to investigate the effects of whey protein with collagen hydrolyzed following resistance training on body composition, muscular strength, functional capacity, and plasma-metabolism…
- Trial name
- NCT04621383
- Testing
- Whey protein plus collagen, Whey protein plus maltodextrin
- Where
- Brazil
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Community-acquired Pneumonia, Urinary Tract Infections
Physical Rehabilitation of Older Persons Following a Community-Acquired Infection Hospitalization - A Randomised-Controlled Trial
Community-acquired infections such as community-acquired pneumonia (CAP) and urinary tract infection (UTI) remain leading causes of hospitalization and death due to infections in older persons in Europe.
- Trial name
- REHAB-CAI (NCT06689280)
- Testing
- Video-supervised home-based exercise training
- Where
- 3 sites in Denmark
- Volunteers
- 460 people
- Sponsor
- Nordsjaellands Hospital
Overweight
The Influence of Honey-flavored Yogurt on Low-grade Inflammation and Gut Health in Middle to Older Aged Women.
A randomized, double-blind, crossover dietary intervention trial will test the effects of 4 weeks of daily honey-flavored yogurt intake on markers of inflammation (Th17 cytokines) and oxidative stress (NOX2, UA, RSNO) and…
- Trial name
- NCT04248127
- Testing
- Honey sweetened yogurt, Sugar sweetened yogurt
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Osteoporosis, Osteopenia
µMRI of Therapeutic Intervention in Postmenopausal Osteoporosis
The purpose of this study is to apply a novel advanced magnetic resonance imaging methodology to evaluate the response to drug intervention involving two treatment arms of postmenopausal participants with osteoporosis, randomized…
- Trial name
- TERIZOL (NCT01153425)
- Testing
- Virtual Bone Biopsy, Teriparatide, Zoledronic Acid
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Pennsylvania
Older Adult
High-intensity Interval Training Combined with Muscle-strength Training in Older Women
Women generally live longer than men but often experience a faster muscle mass loss due to inactivity, which can lead to weakness and disability. Despite these risks, women, particularly older women, are less active than men.
- Trial name
- NCT06825130
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Muscle Atrophy, Muscle Disuse Atrophy
n3 PUFA and Muscle-disuse Atrophy in Older Women
This study will examine the influence of n3 PUFA supplementation on the rate of muscle atrophy in older women undergoing 1 week of unilateral limb immobilization.
- Conditions
- Muscle Atrophy, Muscle Disuse Atrophy, Sarcopenia
- Trial name
- NCT03808519
- Testing
- n3 PUFA-enriched fish oil
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- McMaster University
Depression, Physical Functional Performance
Eccentrically Reinforced Resistance Training vs. Traditional Resistance Training in Sedentary Older Women
There are easily accessible and safe strategies, such as physical exercise, that can contribute to reducing depressive symptoms and to the preservation of physical and executive function in elderly women.
- Conditions
- Depression, Physical Functional Performance, Executive Function
- Trial name
- NCT05910632
- Testing
- Eccentrically strengthened resistance exercise, Traditional resistance training
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Federal University of Vicosa
Condition
"We Walk": Impact of Exercise Dose on Health Outcomes Among Women Ages 60-75
The overall goal is to determine whether any energy expenditure compensation in response to 16 weeks of aerobic exercise at a higher-dose is greater compared to a lower-dose intervention in older women, and to begin to…
- Trial name
- WW (NCT01722136)
- Testing
- Low Dosage, High Dosage
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Participants Must be Women Aged 25 Years or Older, Participants Should Have no Self-reported History of Heart Disease or Stroke
RCT of HeartBot in Women
The goal of this clinical trial is to find out whether an app-based program called HeartBot II, which uses an artificial intelligence (AI) chatbot, can help improve women's awareness and knowledge of heart attacks in women.
- Conditions
- Participants Must be Women Aged 25 Years or Older, Participants Should Have no Self-reported History of Heart Disease or Stroke, Participants Should Have no Terminal Illness or Diagnosed Cognitive Impairment, Including Alzheimer's Disease, Participants Should Not be a Healthcare Professionals or Healthcare Trainees
- Trial name
- HeartBot II (NCT07416734)
- Testing
- HeartBot II Program, Waitlist Control
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Aging, Cognitive Decline
Omega-3 Fatty Acids and Exercise on Mobility and Cognition in Older Women
The study will provide insight into how lifestyle-related interventions, specifically nutrition and exercise can impact the health of older women.
- Trial name
- MOBILE (NCT03228550)
- Testing
- Efamol Active 50+, Aerobic exercise
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bournemouth University
Essential Hypertension
Heat Therapy in Older Hypertensive Women
The prevalence of hypertension is greater in older women than men, while the blood pressure (BP) control rate is lower in older women in US. Uncontrolled hypertension is a major risk factor for cardiovascular morbidity/mortality.
- Trial name
- NCT03857490
- Testing
- Lower leg heat therapy
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- University of Texas Southwestern Medical Center
Anxiety Disorder, Breast Cancer
Mindful Movement Program in Improving Quality of Life in Older Female Breast Cancer Survivors
RATIONALE: Mindful movement is a self-directed activity of mindfulness (intention, attention, and attitude) and physical movement.
- Conditions
- Anxiety Disorder, Breast Cancer, Cancer Survivor, Cognitive/Functional Effects
- Trial name
- NCT00903474
- Testing
- questionnaire administration, study of socioeconomic and demographic variables, CAM exercise therapy
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- City of Hope Medical Center
Cognitive Function, Preclinical, Chronic Kidney Diseases
Exercise Training and Cognitive Function in Kidney Disease
Chronic kidney disease (CKD), affects over 45% of all individuals over 70 years of age. Patients with moderate CKD have more than a two-fold increased risk of cognitive impairment than those without CKD; furthermore, as many as…
- Conditions
- Cognitive Function, Preclinical, Chronic Kidney Diseases, Older Adults
- Trial name
- NCT03197038
- Testing
- Partially supervised home-based walking exercise, Control
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Protein-energy; Imbalance
Assessment of Dietary Protein Needs of Older Women
The purpose of this study is to evaluate dietary protein requirements in elderly women aged 80 years and older using the indicator amino acid oxidation technique.
- Trial name
- NCT01193946
- Testing
- dietary control
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Purdue University
Urinary Incontinence, Stress
To Determine How Effective Duloxetine is in Treating Women 65 Years and Older With Symptoms of Stress Urinary Incontinence, or With a Combination of Stress Urinary Incontinence and Urge Urinary Incontinence Symptoms
The purpose of this study is to determine how effective duloxetine is in treating women who are 65 years of age or older with symptoms of stress urinary incontinence, or with a combination of stress urinary incontinence and urge…
- Trial name
- NCT00244296
- Testing
- Duloxetine hydrochloride
- Where
- 31 sites in France, Germany and 5 more
- Volunteers
- 276 people
- Sponsor
- Eli Lilly and Company
Social Cognition, Healthy Aging
Immersive Group Dance in Virtual Reality and Perceived Social Cohesion in Older Adults
This is a two-arm, parallel-group randomized controlled trial designed to evaluate the effects of an immersive virtual reality (VR)-based group dance program on perceived social cohesion among community-dwelling older adults…
- Conditions
- Social Cognition, Healthy Aging, Loneliness, Social Isolation
- Trial name
- VR-GD-COHESION (NCT07850479)
- Testing
- Immersive VR Group Dance Program, Conventional Light Physical Activity Program
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj