Clinical trials: Older Women
Breast Cancer, Cancer Survivor
Aerobic Exercise, Resistance Exercise, or Flexibility and Relaxation Training in Inactive Older Female Breast Cancer Survivors
RATIONALE: Aerobic exercise, resistance exercise, and flexibility and relaxation training may reduce fatigue and improve the health and quality of life of breast cancer survivors.
- Conditions
- Breast Cancer, Cancer Survivor, Fatigue, Long-term Effects Secondary to Cancer Therapy in Adults
- Trial name
- NCT00662103
- Testing
- exercise intervention, laboratory biomarker analysis, questionnaire administration
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- OHSU Knight Cancer Institute
Sarcopenia
Resistance Exercise Effect on Physical Performance and Functional Status in Sarcopenic Older Women
Aging is characterized by a progressive loss of multiple physical and cognitive abilities. From these changes, the most important one is the loss of muscle mass, which has been called "sarcopenia".
- Trial name
- NCT01829009
- Testing
- Resistance Exercise Group
- Where
- Mexico
- Sponsor
- National Institute of Medical Sciences and Nutrition, Salvador Zubiran
Healthy
Pharmacologic Effects of Darifenacin and Tolterodine on Cardiovascular Parameters in Healthy Subjects
This study will evaluate the pharmacologic effects of exposure to darifenacin and tolterodine on cardiovascular parameters in healthy subjects 50 years of age and older
- Trial name
- NCT00413790
- Testing
- Darifenacin, Tolterodine
- Where
- 12 sites in United States
- Volunteers
- 162 people
- Sponsor
- Novartis
Chronic Kidney Disease (CKD)
Domperidone and the Risk of Serious Adverse Events
This study will assess whether initiating domperidone at doses ≥30 mg/day compared to <30 mg/day in patients with advanced chronic kidney disease (CKD) (estimated glomerular filtration rate [eGFR] <45 mL/min/1.73 m² but not…
- Trial name
- NCT07098078
- Testing
- Domperidone (drug)
- Where
- Canada
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Type 2 Diabetes
The Benefits of Intensive Glycemic Control in Elderly Patients With Type 2 Diabetes
Aims/hypothesis: Populations worldwide are aging and type 2 diabetes is common in individuals aged >80 years. The important issue that needs to be considered is whether tight glycemic control is benefits for elderly patients with…
- Trial name
- NCT00850798
- Testing
- Intensive glycemic control, Conservative glycemic control
- Where
- Taiwan
- Volunteers
- 208 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Frail Elderly Syndrome
Exercise Mediation on Hormonal, Immune and Psychological Well-being in Institutionalized Frail Older Women.
Frailty syndrome is a complex aging expression determined by ontogenetic and phylogenetic factors. Chronic stress has been shown to have immunosuppressive effects, to accelerate immunosenescence and to cause cumulative disorders…
- Trial name
- UC (NCT04435899)
- Testing
- Physical exercise
- Where
- Portugal
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Muscle Protein Synthesis, Sarcopenia
The Impact of a Whole-food Animal-based Versus Plant-based Protein Rich Meal on Muscle Protein Synthesis
Rationale: Food intake stimulates muscle protein synthesis rates. The magnitude of the anabolic response to feeding forms a key factor in regulating muscle mass maintenance.
- Trial name
- MeaL (NCT05151887)
- Testing
- Muscle protein synthesis
- Where
- Netherlands
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Breast Cancer
Vinorelbine in Treating Older Women With Stage IV Breast Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of vinorelbine in treating older women who have stage IV…
- Trial name
- NCT00022152
- Testing
- vinorelbine tartrate
- Where
- 18 sites in United States
- Volunteers
- 25 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Invitro Fertilization
FSH/LH Ratio as a Predictor of IVF Outcome in Young and Older Women
All women had normal uterine cavity determined by previous hysterosalpingography or hysteroscopy. Women with abnormally low Gn as hypothalamic hypogonadism , High LH as PCOS and women with abnormal endocrine functions as abnormal…
- Trial name
- NCT02674178
- Testing
- Invitro fertilization
- Where
- Egypt
- Volunteers
- 235 people
- Sponsor
- Cairo University
Performance Enhancement
Functional vs Traditional Training in Older Women's Health
This study investigates how balance, mobility, strength, gait speed, and health-related quality of life in older adults (65+) are affected after an 8-week training period using the Norwegian national concept for older adults…
- Trial name
- NCT05551000
- Testing
- Experimental, comparator and control
- Where
- Norway
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Patient Acceptance of Health Care, Acute Renal Failure
DETECT-IP: a Clinical Decision Support System and Intelligent Procedures to Counter Some Adverse Drug Events in Older Hospital Patients
Current evidence shows that computerized decision support systems (CDSS) have shown to be insufficiently effective to prevent adverse drug reactions (ADRs) at large scale (e.g. whole hospital).
- Trial name
- DETECT-IP: (NCT05923983)
- Testing
- Clinical decision support, Will not receive Clinical Decision Support
- Where
- France
- Volunteers
- 783 people
- Sponsor
- University Hospital, Lille
Frail Elderly Syndrome
Alleviation by Fisetin of Frailty, Inflammation, and Related Measures in Older Women
This is a pilot study to evaluate whether targeting inflammation will help reduce markers of insulin resistance inflammation, bone resorption and physical dysfunction in elderly women with gait disturbance.
- Trial name
- AFFIRM (NCT03430037)
- Testing
- Fisetin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Arterial Hypertension
Mindfulness-Based and Forest Bathing Interventions for Older Women With Treated Arterial Hypertension
This pilot study, conducted by the Department of Social Medicine and Epidemiology, Faculty of Medicine, University of Rijeka, and funded by the University of Rijeka (project no.
- Trial name
- SHIFT (NCT07709962)
- Testing
- Mindfulness-Based Living Course (MBLC), Forest therapy
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- University of Rijeka
Blood Pressure, Hemodynamic Response
Ischemic Preconditioning in Resistance Exercise in Older Women
This study investigates whether ischemic preconditioning (IPC) can reduce cardiac demand after resistance exercise in older women.
- Conditions
- Blood Pressure, Hemodynamic Response, Rating of Perceived Exertion, Heart Rate
- Trial name
- NCT07497659
- Testing
- Ischemic Preconditioning
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Triangulo Mineiro
Postmenopausal, Female
How Seasons Affect Kidney Health in Post-Menopausal Females
The investigators are assessing how seasonal changes affect kidney function biomarkers in post-menopausal women, an understudied group.
- Trial name
- NCT06866743
- Testing
- There will be no intervention.
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Florida State University
Depressive Symptoms, Aging
Twelve Weeks of Resistance Training is Equally As Effective At Improving Cardiovascular Risk Factors in Older Women with and Without Depression: a Non-randomized Cross-over Trial
Background: the purporse was to evaluate and compare the effects of 12 weeks of resistance training (RT) on cardiovascular disease (CVD) risk factors in older women with and without depressive disorders Methods: We included 79…
- Conditions
- Depressive Symptoms, Aging, Resistance Training, Cardiovascular Risk Factor
- Trial name
- NCT06591325
- Testing
- exercise, Control
- Where
- Brazil
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Hypertension, Aging
Wild Blueberries and Cardiovascular Health in Middle-aged/Older Men and Postmenopausal Women
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. Aging is the primary risk factor for CVD, in large part due to adverse modifications to the arteries.
- Conditions
- Hypertension, Aging, Endothelial Dysfunction, Men
- Trial name
- WB2020 (NCT04530916)
- Testing
- Blueberry Powder
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Urgency Urinary Incontinence, Nocturia
Effect of Behavioral Sleep Intervention on Lower Urinary Tract Symptoms in Older Women
Urgency urinary incontinence (UUI) is common in older people and vastly reduces quality of life, yet the cause and mechanism of disease are not well understood.
- Trial name
- SLAB (NCT05604222)
- Testing
- Mirabegron 50 MG, Brief Behavioral Treatment for Insomnia
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Shachi Tyagi
Endothelial Dysfunction
A Clinical Trial for People HIV+ Age > 50 at Risk for Heart Disease
This research study is to see whether blood vessel function, an early sign of heart disease, improves in HIV-infected men and women who take telmisartan for 12 weeks.
- Trial name
- NCT01578772
- Testing
- Telmisartan
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of California, Los Angeles
Age Problem
Home Accidents Among Turkish Older Men and Women
Background: Home accidents are a significant public health issue in developed and developing countries. The present study aims to identify the factors associated with home accidents among older individuals in Türkiye.
- Trial name
- NCT06514872
- Testing
- prevalance and determinants of home accidents
- Where
- Turkey (Türkiye)
- Volunteers
- 8,225 people
- Sponsor
- Ataturk University