Clinical trials: Olfaction
Newborn Jaundice
Influence of Breast Milk Smell on Newborns Bilirubin Level, Duration of Time Phototherapy and Comfort in Newborns Receiving Phototherapyv
ABSTRACT Purpose: This research was done for the purpose of determining the impact of breast milk smell administered to term infants hospitalized in neonatal intensive care units (NICU) due to physiological jaundice on their…
- Trial name
- NCT05167474
- Testing
- breast milk smell
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Head and Neck Cancer, Lung Cancer
Paclitaxel and Cisplatin Plus Radiation Therapy Followed by Filgrastim in Treating Patients With Recurrent Head and Neck Cancer or Lung Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells.
- Trial name
- NCT00021333
- Testing
- filgrastim, cisplatin, paclitaxel
- Where
- 18 sites in United States
- Volunteers
- 29 people
- Sponsor
- Fox Chase Cancer Center
Adult With Stroke and Olfaction's Complaint
REEDUCATION OF OLFACTORY DISORDERS AFTER A CEREBRAL VASCULAR ACCIDENT IN ADULTS
Study context: The literature identifies more and more research revealing olfactory disorders, with a high frequency after an acquired brain injury.
- Trial name
- RE-OLF (NCT04703218)
- Testing
- olfactory rehabilitation
- Where
- France
- Volunteers
- 3 people
- Sponsor
- University Hospital, Caen
Cancer
Evaluation of the Therapeutic Approach of Aromatherapy by Olfaction of Essential Oils in Association With Hypnosis in the Management of Patients Followed for Cancer
Patients having the following gestures (blood test, change of dressing for cancerous lesion and complete toilet in bed) will be identified by the team of the medical oncology department.
- Trial name
- HYPNO-AROMA (NCT05714995)
- Testing
- hypnosis, Hypnosis with aromatherapy
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Covid-19
Retrospective Study on Anosmias and Ageusias Linked to Infection by Covid-19
Odor and taste disturbances have increased dramatically during this time of the COVID-19 pandemic. Currently, we have very little information on the demographic and clinical characteristics of the affected population, on the…
- Trial name
- STras-Cov-2 (NCT04681157)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Strasbourg, France
Parkinson Disease, Olfactory Disorder
The Efficacy of Olfactory Training Intervention on Olfactory and Other Non-motor Symptoms in PD
To explore the efficacy of olfactory training on olfactory and other non-motor symptoms in PD.
- Conditions
- Parkinson Disease, Olfactory Disorder, Olfactory Training
- Trial name
- NCT06607653
- Testing
- Olfactory training
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
Bladder Cancer, Breast Cancer
Chemotherapy in Treating Patients With Solid Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I/II trial to study the effectiveness of oblimersen in treating patients who have solid tumors…
- Conditions
- Bladder Cancer, Breast Cancer, Colorectal Cancer, Esophageal Cancer
- Trial name
- NCT00003103
- Testing
- oblimersen sodium, docetaxel
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer, Chemotherapy-related Cognitive Impairment
Evaluation of Cognitive Education Activities in Breast Cancer Patients Receiving Chemotherapy
Breast cancer is one of the most common cancer types worldwide and accounts for approximately 31% of all cancers in women. The global incidence of breast cancer is increasing, making it a significant public health problem.
- Trial name
- NCT07570251
- Testing
- Cognitive Function Training Activities
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Saglik Bilimleri Universitesi
Hematologic Cancer, Undernutrition
CAncer, NUtrition and Taste - Validation of the CANUT-QVA Questionnaire on Eating Habits in Cancer Patients
Cancer patients are at high risk of undernutrition, which is generally more pronounced for solid tumours (upper digestive tract, Ear Nose and Throat (ENT), bronchial tubes).
- Conditions
- Hematologic Cancer, Undernutrition, Chemotherapy Effect, Taste Disorders
- Trial name
- CANUT-QVA (NCT04235153)
- Testing
- Evaluation of the 9 dimensions of the CANUT-QVA questionnaire
- Where
- France
- Volunteers
- 127 people
- Sponsor
- Hospices Civils de Lyon
Bipolar Disorder
OLFACTION AND BIPOLAR DISODER
To compare olfactory performance between patients with BD and HC and correlate their performances to neuroimaging data
- Trial name
- OLF-BP (NCT06809881)
- Testing
- olfactory testing, MRI acquisition, clinical assessment
- Where
- France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Anosmia
Coronavirus Smell Therapy for Anosmia Recovery
As the COVID-19 pandemic spread around the world, anosmia and dysgeusia were quickly recognized as two of the key presenting symptoms.
- Trial name
- Co-STAR (NCT04422275)
- Testing
- Budesonide, High-Concentration Essential Oil, Low-Concentration Essential Oil
- Where
- United States
- Sponsor
- Washington University School of Medicine
Glaucoma
Assessment of the Ability to Distinguish Odors in Glaucoma Patients
Glaucoma is one of the leading causes of blindness worldwide. The key feature of glaucoma is damage to the optic nerve head with loss of retinal ganglion cells and local tissue remodeling.
- Trial name
- NCT00304824
- Volunteers
- 30 people
- Sponsor
- University Hospital, Basel, Switzerland
Cancer
Thalidomide and Docetaxel in Treating Patients With Advanced Cancer
RATIONALE: Thalidomide may stop the growth of cancer by stopping blood flow to the tumor. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die.
- Trial name
- NCT00049296
- Testing
- docetaxel, thalidomide
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Case Comprehensive Cancer Center
Adult Anaplastic Astrocytoma, Adult Anaplastic Ependymoma
Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer
Bevacizumab may reduce CNS side effects caused by radiation therapy. This randomized phase II trial is studying how well bevacizumab works in reducing CNS side effects in patients who have undergone radiation therapy to the brain…
- Conditions
- Adult Anaplastic Astrocytoma, Adult Anaplastic Ependymoma, Adult Anaplastic Meningioma, Adult Anaplastic Oligodendroglioma
- Trial name
- NCT00492089
- Testing
- bevacizumab, magnetic resonance imaging, quality-of-life assessment
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- National Cancer Institute (NCI)
Olfactory Dysfunction, Smell Loss
Scents of Progress: Leveraging a Novel Device for Olfactory Training in Older Adults
The goal of this clinical trial is to learn if ScentCare, a novel olfactory training device and accompanying companion web-based application, will lead to improved olfactory and well-being outcomes in elderly patients with…
- Conditions
- Olfactory Dysfunction, Smell Loss, Anosmia, Hyposmia
- Trial name
- SPLENDOR-OA (NCT06733636)
- Testing
- Sudoku Puzzles, ScentCare (Olfactory Training Device)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Johns Hopkins University
Substance Use Disorders, Opioid Use Disorder
Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Substance Use Disorders
The overarching goal of this study phase, Phase II component is to implement Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Substance Use Disorders (EDITOR) device in substance use disorder (SUD)…
- Conditions
- Substance Use Disorders, Opioid Use Disorder, Alcohol Use Disorder, Cocaine Use Disorder
- Trial name
- EDITOR (NCT06434818)
- Testing
- EDITOR (CBOT with olfactory stimulants, OFC tasks & remote monitoring of treatment compliance), CBOT with olfactory stimulants & OFC tasks
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Evon Medics LLC
Breast Cancer, Head and Neck Cancer
Photodynamic Therapy in Treating Patients With Skin Cancer or Solid Tumors Metastatic to the Skin
RATIONALE: Photodynamic therapy uses light and drugs that make cancer cells more sensitive to light to kill tumor cells. This may be effective treatment for skin cancer and cancer that is metastatic to the skin.
- Conditions
- Breast Cancer, Head and Neck Cancer, Lymphoma, Metastatic Cancer
- Trial name
- NCT00023790
- Testing
- silicon phthalocyanine 4
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Case Comprehensive Cancer Center
Olfaction Disorders
Evaluation of Two Methods of Olfactory Rehabilitation in Post-viral Loss of Smell: Classic and Intensive
One of the most common causes of loss of smell is upper respiratory tract infection. These disorders can be quantitative (hyposmia or anosmia) or qualitative (parosmia or phantosmia).
- Trial name
- Odorat-Covid (NCT04598763)
- Testing
- smell the odors of the olfactory rehabilitation kit according to the classic or intensive method
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Central Hospital, Nancy, France
Epilepsy
An Open-Label, Safety and Tolerability Study of Chronic Intermittent Use of Diazepam Nasal Spray.
This study will assess long-term safety and tolerability of repeat dose diazepam nasal spray in adolescents and adults with cluster seizures, with a focus on potential local effects (changes in nasal mucosa, olfaction, and taste).
- Trial name
- NCT02316847
- Testing
- diazepam nasal spray
- Where
- 33 sites in United States
- Volunteers
- 126 people
- Sponsor
- Acorda Therapeutics
Preoperative Olfactory Training, Postoperative Delirium
Effect of Preoperative Olfactory Training on Postoperative Delirium in the Elderly Undergoing Orthopedic Surgeries
To observe whether preoperative olfactory training can reduces the incidence of postoperative delirium in elderly patients undergoing orthopedic surgeries, a prospective randomized controlled study method will be used in this…
- Trial name
- NCT05908318
- Testing
- olfactory training
- Volunteers
- 450 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University