Clinical trials: Olfaction
Covid19, Nasopharyngitis
BNO 1030 Extract (Imupret) in the Treatment of Mild Forms of COVID-19
According to WHO (World Health Organisation) data, about 40% of patients with COVID-19 (Corona Virus SARS-CoV-2) have a mild course of the disease, namely, cases of mild course are of great danger from the point of view of the…
- Conditions
- Covid19, Nasopharyngitis, Anosmia, Fever
- Trial name
- NCT04797936
- Testing
- BNO 1030, Standard care
- Where
- Ukraine
- Volunteers
- 133 people
- Sponsor
- Ivano-Frankivsk National Medical University
Alzheimer Disease, Smell Loss
Olfactory Biopsies
This research study aims to investigate the function of the olfactory lining in the nasal cavity and its potential alterations in both healthy and diseased conditions. The olfactory lining is involved in the sense of smell.
- Conditions
- Alzheimer Disease, Smell Loss, Smell Dysfunction
- Trial name
- NCT07021040
- Testing
- olfactory testing, Odor stimulation, Olfactory biopsy
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Duke University
Taste Alterations, Smell Disorder
Adaptation Strategies for Coping With the Impact of Sensory Alterations on Eating Behavior in Children With Cancer: A Qualitative Study From the Perspective of Children and Parents
Childhood cancer is a serious and life-changing disease that affects thousands of children every year worldwide. In addition to the disease itself, cancer treatments such as chemotherapy often cause difficult side effects.
- Conditions
- Taste Alterations, Smell Disorder, Eating Behavior Changes
- Trial name
- QUALISENS (NCT07490093)
- Testing
- No Intervention: Observational Cohort
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Leon Berard
Sinusitis
Olfactory Dysfunction of Rhinosinusitis - Cyclic Adenosine Monophosphate (cAMP)/Calcium Signaling Study
The study examines the biochemistry underlying human olfaction in both normal and diseased states. The study aims are: 1. to determine the levels of cAMP in olfactory tissue from people with chronic rhinosinusitis and other nasal…
- Trial name
- cAMP (NCT00970190)
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Greg Davis
Olfactory Dysfunction
Olfactory Training in Chronic Rhinosinusitis
Persons with a loss of sense of smell, who agree to participate in this study, will be assigned to one of three groups: two groups will have smell training and the third group will not do smell training.
- Trial name
- NCT03055572
- Testing
- Olfactory Training with Essential Oils, Olfactory Training with Pure Fragrance Oils
- Sponsor
- Emory University
Drug Abuse
The Effects of Expectation on Natural and Drug -Induced Rewards
Background: Environmental cues frequently induce expectancies in individuals that may strongly influence the actual experience associated with the cue.
- Trial name
- NCT01036230
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Coronavirus Disease 2019
Olfactory and Neurosensory Rehabilitation in COVID-19-related Olfactory Dysfunction
A combination of oral vitamin A (VitA) and intense aromatic chemosensory smell training (ST) by pulse aromatic stimulation will expedite the neurosensory recovery of olfaction in patients suffering from prolonged COVID-19-related…
- Trial name
- NCT04900415
- Testing
- Vitamin A, Electronic portable aromatic rehabilitation (EPAR) diffuser
- Where
- 2 sites in Hong Kong
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Ivan FN Hung MD
Menopause, Hot Flashes
Aromatherapy and Yogatherapy for Hot Flashes
The purpose of this study is to verify and analyse psychological and physiological effects of olfactory aromatherapy and yogatherapy respiratory exercises, together and separately, on the quality of life, levels of stress…
- Conditions
- Menopause, Hot Flashes, Hot Flushes
- Trial name
- NCT01816360
- Testing
- Olfactory aromatherapy, Yogatherapy
- Where
- Brazil
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Covid19
Physical Activity and Smell Trainings to Help Individuals With Coronavirus Disease (COVID-19) Recover From Persistent Smell and Taste Impairments - A Pilot Study
The primary objective of this study is to identify efficient treatments to help those with chemosensory losses due to Coronavirus disease (COVID-19).
- Trial name
- CAPS (NCT05037110)
- Testing
- Physical activity, Smell training
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- Université de Montréal
Anxiety
"Pain and Emotional Changes on Relationships Between Anxiety and Olfaction"
Introduction: This prospective study aimed to assess the impact of olfaction on providing positive emotional responses and reducing dental anxiety and pain.
- Trial name
- NCT06066073
- Testing
- Lavender Oil, Distal Water
- Where
- Saudi Arabia
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Qassim University
Estimate, With the Contribution of Optimized MRI, the Prevalence of Neurological and Neurovascular Manifestations on Imaging in the Event of SARS-CoV-2
Imaging SARS-CoV-2 Involvement of Leptomeninges, Olfactory and Limbic Areas
When patients arrive in the waiting room of the MRI department, patients will be given the briefing note explaining the purpose of the study and how it is going.
- Trial name
- ICILOLA (NCT04448054)
- Testing
- MRI
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Human Olfactory Amygdala Function
Characterization of Human Olfactory Amygdala Subregions Exp3
We aim to better understand the functions of the subregions of the human amygdala that receive direct projections from the olfactory bulb
- Trial name
- NCT07060651
- Testing
- Present odors to participants while recording and stimulating brain activity
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Olfactory Neuroblastoma, Esthesioneuroblastoma
A Natural History Study of Children and Adults With Olfactory Neuroblastoma
Background: Olfactory neuroblastoma (ONB) is a rare cancer. It grows from tissue in the upper part of the nose cavity, related to the sense of smell and can affect a person s sense of smell.
- Trial name
- NCT04755205
- Where
- United States
- Volunteers
- 525 people
- Sponsor
- National Cancer Institute (NCI)
Neurotoxic Effect of Sevoflurane-Based Anaesthesia
Evaluation of Neurotoxic Effect of Sevoflurane-Based AnaesthesiaGuided by Short-Term Olfactory Identification
Nowadays there is increasing doubts about the safety of anesthesia . Anesthesiologists have to console the worried patients, who are anxious about the potential risks of anesthetic-induced brain damage, by suggesting that any…
- Trial name
- NCT03726580
- Testing
- Sevoflurane
- Where
- Egypt
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Tanta University