Clinical trials: Omega 3 Fatty Acids, active
Hypertriglyceridemia, Normal
Cardiometabolic Properties of Omega-3 Functionalized With Hydroxytyrosol
The primary aim of this study is to investigate the potential cardioprotective effects of daily nutritional doses of eicosapentaenoic acid (EPA) enriched with hydroxytyrosol (HT) on cardiovascular health, as well as its…
- Trial name
- HydroxyOmega (NCT06992323)
- Testing
- EPA + HT, EPA, Sunflower Oil
- Where
- Spain
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- National Research Council, Spain
Hypertriglyceridemia
Evaluation of the Efficacy of Phospholipid-Bound Omega-3 Versus Omega-3 Alone in Patients With Hypertriglyceridemia: A Randomized Clinical Trial
Hypertriglyceridemia is a significant risk factor for cardiovascular diseases. Omega-3 fatty acids have been shown to reduce triglyceride levels, and their combination with phospholipids could offer additional benefits in…
- Trial name
- OMEGA-PHYT (NCT06749028)
- Testing
- Intervention Arm: Omega-3 + Phospholipids., Comparator Arm: Omega-3 alone.
- Where
- Colombia
- Volunteers
- 44 people
- Sponsor
- Fundación del Caribe para la Investigación Biomédica
Omega 3 Fatty Acids, Dementia
NMDA Enhancement Combined With Omega-3 for Early Dementia
In this 4-year proposed project, we will enroll 140 patients with aMCI or mild AD into a 24-week randomized, double-blind, placebo-controlled drug trial.
- Trial name
- NCT05181189
- Testing
- DAOIB+Omega-3
- Where
- Taiwan
- Volunteers
- 140 people
- Sponsor
- Chang Gung Memorial Hospital
Diabetic Neuropathies
Omega-3 Fatty Acid Lipidomics in Diabetes Peripheral Neuropathy
Diabetic peripheral neuropathy (DPN) is the most common chronic complication of diabetes, affecting about 50% of patients with diabetes and leading to severe morbidity, poor quality of life, high mortality, and high health care…
- Trial name
- NCT05169060
- Testing
- Fish Oil Concentrate, 1000 Mg Oral Capsule, Salsalate Oral Tablet
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Iowa
Mixed Dyslipidemia
ATLANTIS Trial: Phospholipid Omega-3 Versus Conventional Omega-3
This study is a clinical trial designed to compare two forms of omega-3 supplements in adults with mixed dyslipidemia. Mixed dyslipidemia is a condition in which blood fat levels, such as triglycerides and cholesterol, are not…
- Trial name
- ATLANTIS (NCT07394517)
- Testing
- Phospholipid Omega-3, Triglyceride Omega-3
- Where
- Colombia
- Volunteers
- 105 people
- Sponsor
- Fundación del Caribe para la Investigación Biomédica
Fatty Acids, Omega-3
Evaluation of the Nutritional Status of Omega-3 Fatty Acids and the Possible Influences of Dietary Patterns and Different Socioeconomic Factors, in a Spanish Population Over 60 Years of Age
The long-chain polyunsaturated fatty acids (PUFA) of the n-3 or omega-3 series and, in particular, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), both derived from the essential fatty acid alpha-linolenic acid, are…
- Trial name
- OMEGAPRED (NCT06916455)
- Where
- Spain
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Tuberculosis, Inflammation Biomarkers
Effects of Adjunct Omega-3 Long Chain Polyunsaturated Fatty Acids in Pulmonary Tuberculosis Patient: an Early Bactericidal Activity and Inflammatory Trial
The goal of this randomized controlled trial is to evaluate the early bactericidal activity, early inflammatory response, and safety of omega-3 long chain polyunsaturated fatty acid (n-3 PUFA) supplementation in adult patients…
- Conditions
- Tuberculosis, Inflammation Biomarkers, Liver Function Tests, Iron Status
- Trial name
- TREAT 3 (NCT07118059)
- Testing
- Omega-3 (EPA+DHA)
- Where
- South Africa
- Volunteers
- 40 people
- Sponsor
- North-West University, South Africa
Omega 3 Fatty Acids, Coronary Arterial Disease (CAD)
Investigation of the Effects of Omega-3 Supplementation in Chronic Kidney Disease Patients Diagnosed With Coronary Artery Disease and Dyslipidemia
Chronic kidney disease (CKD) is characterized by the slow, progressive, and irreversible loss of kidney function. Uremic toxins in CKD patients trigger an inflammatory response driven by various cytokines, chemokines, and other…
- Conditions
- Omega 3 Fatty Acids, Coronary Arterial Disease (CAD), Chronic Kidney Disease(CKD)
- Trial name
- NCT07127068
- Testing
- Omega-3 Suplementation, No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- University of Beykent
ADHD
Omega-3 Fatty Acids, Inflammation, Gut Microbiota in Youth With Depression
This is a 12 week double blind RCT aimed to investigate the role of omega-3 fatty acids in patients with major depressive disorder
- Trial name
- OMIMYDep (NCT07363551)
- Testing
- Omega-3 fatty acids
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- China Medical University Hospital
Perinatal Depression, PerinatalAnxiety
Perinatal Depression & Anxiety (PDA) and Maternal Gut Microbiome
Perinatal depression and anxiety (PDA) are the leading causes of maternal mortality in developed countries. Women with a history of depression have a 20 fold higher risk of PDA at subsequent pregnancies.
- Trial name
- NCT06074250
- Testing
- Fish oil, Probiotics, Prebiotics
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- The Canadian College of Naturopathic Medicine
Cardiovascular (CV) Risk, Inflammation
RESOLving INflammation Through Diet for Health (RESOLVIN)
Hyperlipidemia is the main driver of atherosclerotic cardiovascular disease (ASCVD), both through direct effects and as trigger of the chronic inflammation behind a cardiovascular health-to-disease transition.
- Conditions
- Cardiovascular (CV) Risk, Inflammation, Omega 3
- Trial name
- RESOLving (NCT07331103)
- Testing
- Fish Oil, Camelina oil, Vitamin E
- Where
- 9 sites in Italy
- Volunteers
- 324 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Docosahexaenoic Acid Content of the Participants, Docosahexaenoic Acid Content of the Breast Milk
Effectiveness of Nutritional Resources for Milk Donors
Maternal diet influences breast milk nutritional profile; however, a national survey undertaken by the researchers revealed that non-for-profit donor milk banks in the U.K. do not provide specific dietary information to donors.
- Trial name
- VITAMIN (NCT07042009)
- Testing
- Nutritional resources, Milk docosahexaenoic acid levels
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Roehampton
Maternal and Neonatal Outcomes, Pregnancy
Omega-3 Egg Intervention and Nutrition Education in Pregnant Women
The goal of this clinical trial is to evaluate the effect of omega-3 enriched egg supplementation combined with nutrition education in pregnant women with Chronic Energy Deficiency (CED).
- Conditions
- Maternal and Neonatal Outcomes, Pregnancy, Malnutrition Pregnancy
- Trial name
- OMEGA-MOM (NCT07863206)
- Testing
- Omega-3 Enriched Eggs, nutrition education
- Where
- Indonesia
- Volunteers
- 42 people
- Sponsor
- Institut Pertanian Bogor
Heart Health Markers, Cardiovascular Diseases
Omega-3D: Omega-3 for Diet-Driven Health Disparities
The goal of this clinical trial is to learn whether omega-3 fatty acid supplementation can reduce inflammation-related biomarkers and improve cardiovascular health in healthy adult volunteers with different genetic backgrounds.
- Conditions
- Heart Health Markers, Cardiovascular Diseases, Omega 3 Fatty Acids
- Trial name
- NCT07078344
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Nutritional Status, Micronutrient Status
Health and Nutritional Outcomes Among Young Females and Children in Southwest Bangladesh
This study aims to examine how societal and climate changes influence the nutritional status and fish consumption of young women over a 10 year period in southern Bangladesh, and how these factors affect their children's health.
- Conditions
- Nutritional Status, Micronutrient Status, Omega 3 Fat Status, Diet Diversity
- Trial name
- AQUAFOOD (NCT07541742)
- Testing
- The follow-up aims to evaluate natural changes occurring from adolescence to young adulthood with respect to the study objectives due to lifestyle and environmental factors, without any intervention.
- Where
- Bangladesh
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Obesity
Concentration of n-3 PUFA Monohydroxylated Derivatives in Adults With Obesity After n-3 PUFA Supplementation.
The goal of this clinical trial is to learn if daily supplementation with SPM Active® can increase omega 3 polyunsaturated fatty acid derivatives and improve well-being in adults with obesity.
- Trial name
- NCT06991296
- Testing
- SPM Active®
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of North Carolina, Chapel Hill
Atherosclerosis Cardiovascular Disease
Effect of Icosapent-ethyl Ester (IPE) to Reduce the Residual Risk Cardiovascular Disease.
Cardiovascular diseases (CVDs) are the leading cause of global mortality, despite significant advances in prevention and treatment.
- Trial name
- NCT06720662
- Testing
- Icosapent-ethyl ester capsules, Corn oil Control
- Volunteers
- 294 people
- Sponsor
- University of Sao Paulo
Esophageal Neoplasms
Omega-3 Fatty Acids With PD-1 Inhibitors in Advanced Esophageal Cancer
This is a randomized, double-blind, placebo-controlled phase II clinical trial designed to evaluate whether adding omega-3 fatty acids improves outcomes in adult patients with recurrent or metastatic esophageal cancer receiving…
- Trial name
- ESO-Shanghai28 (NCT07272382)
- Testing
- PD-1 + Omega-3 Fatty Acids (EPA/DHA)
- Where
- China
- Volunteers
- 142 people
- Sponsor
- Fudan University
Cognitive Dysfunction, Alzheimer Disease
ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults
This randomized, double-blind, placebo-controlled pilot trial will evaluate the effects of alpha-linolenic acid (ALA) supplementation on cognitive function, blood-brain barrier integrity, and brain vascular health in older adults…
- Conditions
- Cognitive Dysfunction, Alzheimer Disease, Blood-Brain Barrier, Apolipoprotein E, Deficiency or Defect of
- Trial name
- NCT07392723
- Testing
- Alpha-Linolenic Acid (2.6 g/day)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Michal Schnaider Beeri, Ph.D.
Breast Cancer, Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS)
Tart Cherry and Omega-3's for Aromatase Inhibitor Musculoskeletal Symptoms
Both Tart Cherry and Omega 3 FAs have better side effect profiles compared to other commonly used medications for AIMSS, such as nonsteroidal anti-inflammatories, steroids, and serotonin norepinephrine reuptake inhibitors.
- Conditions
- Breast Cancer, Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS), Joint Pain
- Trial name
- NCT06123286
- Testing
- Tart Cherry, Omega 3 FA (Fish Oil)
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Philip Chang