Clinical trials: Omega-3 Fatty Acids
Coronary Artery Disease, Arrhythmia
Effect of Supplemental Intake of Omega-3 Polyunsaturated Fatty Acids on the Rate and Complexity of Spontaneously Occurring Ventricular and Supraventricular Arrhythmias in Patients With Implantable Cardioverter Defibrillator (ICD) - A Randomized Clinical Trial
We hypothesize that oral supplementation with omega-3 PUFA will decrease occurrence of arrhythmic events among post-MI, ICD recipients.
- Trial name
- NCT00290056
- Testing
- Eicosapentanoic acid (EPA) and Docosahexanoic acid (DHA).
- Where
- 2 sites in Israel
- Volunteers
- 105 people
- Sponsor
- Sheba Medical Center
Type 2 Diabetes
n-3 Fatty Acid Infusion and Type 2 Diabetes
The purpose of this experimental study is to investigate whether an acute lipid infusion added marine n-3 fatty acids produces effects on insulin sensitivity in subjects with type 2 diabetes, when compared with an acute lipid…
- Trial name
- NCT00829569
- Testing
- Intralipid +/- Omegaven
- Where
- Norway
- Volunteers
- 11 people
- Sponsor
- St. Olavs Hospital
Colorectal Cancer, Nutritional Deficiency
PeRioperative Omega Three and the Effect on ImmuNity
Bowel cancer is the second most common cause of cancer-related death in the UK, with 50,000 new cases and over 15,000 deaths annually.
- Conditions
- Colorectal Cancer, Nutritional Deficiency, Infected Wound, Surgical Site Infection
- Trial name
- PROTEIN (NCT03598413)
- Testing
- Omega-3
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust
Healthy Subjects
A Ph 1 Study of Epanova® in Healthy Chineses
The purpose of this study is to explore the safety, tolerability, and PK of single and multiple doses of Epanova in healthy male and female Chinese subjects and to allow comparison of these parameters with the Western population…
- Trial name
- NCT03574142
- Testing
- Epanova
- Where
- China
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy
Assessment of PCSO-524 Relative to a Comparator Product
A marine lipid oil extract isolated from the New Zealand Greenshell® Mussel, Perna canaliculus (P. canaliculus), contains a unique synergistic blend of marine fatty acids.
- Trial name
- NCT01564160
- Testing
- Fish Oil, PCSO-524
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Nutrasource Pharmaceutical and Nutraceutical Services, Inc.
Pancreatic Neoplasms
A Study of the Effect of Gemcitabine With Fish Oil in Patients With Advanced Pancreatic Cancer
Over 7000 patients are diagnosed with pancreas cancer every year in the UK. Only 10% have it caught early enough to have surgery to cure it.
- Trial name
- NCT01019382
- Testing
- Lipidem fish oil infusion + Gemcitabine chemotherapy
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University Hospitals, Leicester
Carcinoma Surgery, Parenteral Nutrition
The Impact of Omega-3 Fat Emulsion on Clinical Outcome of Post-Operative Cancer Patients
The purpose of this study is to evaluate clinical safety and effect of Omega-3 fat oil emulsion on outcome in post-operative cancer patients.
- Conditions
- Carcinoma Surgery, Parenteral Nutrition, Post-Operative Hospital Stay
- Trial name
- NCT00292279
- Testing
- Omega-3 fish oil emulsion (Omegaven ), long-chain triglyceride
- Where
- 5 sites in China
- Volunteers
- 206 people
- Sponsor
- Sino-Swed Pharmaceutical Corporation
Assess Effect of Omega-3 Fish Oil in Patients With Severe Acute Pancreatitis
Effects Of Fish Oil Emulsion On Severe Acute Pancreatitis Patients
The incidence of acute pancreatitis in UK has risen sharply over the past 40 years. Recent reports suggest that 56.5 per 100 000 of the population will suffer from AP annually; this figure is more than double the highest previous…
- Trial name
- NCT01745861
- Testing
- Lipidem (Omega-3 fish oil lipid emulsion), Lipofundin® MCT/LCT 20%
- Where
- United Kingdom
- Volunteers
- 44 people
- Sponsor
- University Hospitals, Leicester
Severe Hypertriglyceridemia
Epanova® Compared to Lovaza® In a Pharmacokinetic, Single-dose, Evaluation
The objectives of this study are to compare the relative bioavailabilities of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in plasma from a single dose of Epanova or Lovaza during periods of high- and low -fat…
- Trial name
- ECLIPSE (NCT01208961)
- Testing
- Epanova (4 g) and Lovaza (4 g), Lovaza (4 g) and Epanova (4 g)
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Joint Function Disorder
Efficacy of a Dietary Ingredient Combination With Omega-3 for Joint Function
Randomized, controlled, double-blind intervention study of four parallel branches depending on the product consumed, to analyze the efficacy of an Omega-3 based product on the mobility and functionality of the evaluated joint.
- Trial name
- 7DHA (NCT05279573)
- Testing
- Omega-3 and/or botanical ingredient, Control product consumption
- Where
- Spain
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Chronic Metabolic Disorder, Lipid Metabolism Disorders
Randomized Clinical Trial of HMR(Home Meal Replacement)-Type Omega-3-balanced-diet
Investigate whether HMR(Home meal replacement)-type omega-3-balanced-diet can improve clinical laboratory values related to chronic metabolic diseases through reducing lipids and chronic inflammation, and can prevent muscle loss.
- Conditions
- Chronic Metabolic Disorder, Lipid Metabolism Disorders, Sarcopenia
- Trial name
- NCT04552574
- Testing
- HMR(Home meal replacement)-type omega-3-balanced diet
- Where
- South Korea
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Chungbuk National University Hospital
Parenteral Nutrition Associated Liver Disease PNALD, Cholestasis
Evaluation of Omegaven™ Parenteral Nutrition in Patients With Total Parenteral Nutrition (TPN)-Induced Cholestasis
The purpose of this study is to determine if established parenteral nutrition (PN) associated liver disease can be reversed or its progression halted by using a parenteral fat emulsion prepared from fish oil as measured by…
- Trial name
- NCT00826020
- Testing
- Omegaven™
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Nebraska
Ischemic Stroke, Transient Ischemic Attack
Lovaza's Effect on Clopidogrel in a Neuro Population
In patients who have suffered an ischemic stroke or TIA (mini-stroke), as well as in patients who are candidates for neuroendovascular stenting, it is standard of care to treat these patients with antiplatelet therapy, or…
- Trial name
- NCT01526824
- Testing
- omega-3 polyunsaturated fatty acids (Lovaza)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Millard Fillmore Gates Hospital
Cognitive Change, Mood
The Acute Effect of a Walnut Intervention on Cognitive Performance, Brain Activation, and Serum Markers of Inflammation in Young Adults
This study investigates the effect of acute walnut consumption on the cognitive behaviour, mood, brain activation, and markers of inflammation in young adults.
- Conditions
- Cognitive Change, Mood, Inflammatory Response, Brain Derived Neurotrophic Factor Level
- Trial name
- WalCog (NCT04075448)
- Testing
- Control, 50 g Walnut
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Reading
Role of Omega-3 Polyunsaturated Fatty Acid in the Management of Major Depressive Disorder: A Randomized Controlled Trial
Role of Omega-3 Polyunsaturated Fatty Acid in the Management of Major Depressive Disorder.
Background: Patients with major depressive disorder have prominently been reported to be related with subnormal polyunsaturated omega-3 fatty acids levels, importantly low docosahexaenoic acid and eicosapentaenoic acid in plasma…
- Trial name
- NCT03732378
- Testing
- Omega-3 capsule
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Allama Iqbal Open University Islamabad
Breast Cancer, Precancerous Condition
Omega-3 Fatty Acids in Treating Women With Newly Diagnosed Ductal Carcinoma In Situ and/or Atypical Ductal Hyperplasia
RATIONALE: Polyunsaturated fatty acids are important for normal growth and development. One type, called omega-3 fatty acids (found in fish, fish oil, and some other foods), may affect the growth of abnormal breast cells.
- Trial name
- NCT00627276
- Testing
- omega-3 fatty acid
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- OHSU Knight Cancer Institute
Myocardial Infarction, Heart Failure
Omega-3 Fatty Acids in Elderly Patients With Acute Myocardial Infarction
The aim of the present study is to investigate the possible effects of supplementation with 1.8 g/day of n-3 polyunsaturated fatty acids on cardiovascular morbidity and mortality during a follow-up period of 2 years in an elderly…
- Conditions
- Myocardial Infarction, Heart Failure, Myocardial Revascularization, Atrial Fibrillation
- Trial name
- OMEMI (NCT01841944)
- Testing
- Pikasol, Corn oil
- Where
- 4 sites in Norway
- Volunteers
- 1,027 people
- Sponsor
- Oslo University Hospital
Evaporative Dry Eye Disease
Safety and Efficacy of NovaTears® + Omega-3 (0.2%) Eye Drops on Signs and Symptoms of Dry Eye
This PMCF study is carried out following successful CE marking of NovaTears® + Omega-3 and is intended to generate systematic clinical data on the safety and performance of the device when used in accordance with the intended…
- Trial name
- NCT04521465
- Testing
- NovaTears® + Omega-3 (Perfluorohexyloctane with 0.2% w/w Omega-3 fatty acid ethyl esters)
- Where
- 2 sites in Germany
- Volunteers
- 36 people
- Sponsor
- Novaliq GmbH
Hypertension, Kidney Diseases
Effects of Vitamin D and Fish Oil on the Kidney in Hypertensives
The VITamin D and OmegA-3 TriaL (VITAL; NCT01169259) is an ongoing randomized clinical trial in 25,875 US men and women investigating whether taking dietary supplements of vitamin D3 (2000 IU) or omega-3 fatty acids (Omacor (R)…
- Trial name
- NCT02757872
- Testing
- Vitamin D3, Omega-3 Fatty acids
- Where
- United States
- Volunteers
- 2,232 people
- Sponsor
- Albert Einstein College of Medicine
Pharmacokinetics
Comparing the Pharmacological Profile of Formulations Containing Omega 3 Fatty Acids
The primary objective of this study is to investigate the uptake/gastrointestinal absorption of fatty acids in healthy adult volunteers by using enteric coated and non-enteric coated soft capsules containing omega 3 fatty acids.
- Trial name
- NCT05394701
- Testing
- Omega-3 LipoMicel® soft gels, RxOmega-3 soft gels (Enteric), Omega-3 Complete soft gels (Non-Enteric)
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Factors Group of Nutritional Companies Inc.