Clinical trials: Oncologic
Esophageal Cancer, Gastric Cancer
Fluorescence Image Guided Foregut Surgery
A high number of resected lymph nodes is an independent prognostic factor for improved survival after esophagectomy or gastrectomy for cancer.
- Trial name
- FOREGUT (NCT04734821)
- Testing
- Near Infra-Red Fluorescence Guided Surgery
- Where
- France
- Volunteers
- 60 people
- Sponsor
- IHU Strasbourg
Breast Cancer
Clinical Trial Evaluating the Efficacy and Implementation of an Early Adapted Physical Activity to Prevent and Manage Aromatase Inhibitor-induced Musculoskeletal Pain in Breast Cancer (APIS)
Aromatase inhibitors (AI) are the standard adjuvant hormone therapy for postmenopausal women with hormone-sensitive breast cancer.
- Trial name
- APIS (NCT07295457)
- Testing
- Adapted Physical Activity started early, Adapted Physical Activity begins at the start of hormone therapy
- Where
- 2 sites in France
- Volunteers
- 182 people
- Sponsor
- Hospices Civils de Lyon
Anal Cancer, Anxiety Disorder
Psychological and Emotional Impact in Patients Undergoing Treatment For Metastatic Cancer Either in a Clinical Trial or as Standard Off-Trial Therapy
RATIONALE: Gathering information from patients who received treatment for metastatic cancer while participating in a phase II or phase III randomized clinical trial and from patients receiving standard treatment off-trial may…
- Conditions
- Anal Cancer, Anxiety Disorder, Breast Cancer, Depression
- Trial name
- NCT00896467
- Testing
- questionnaire administration, psychosocial assessment and care, quality-of-life assessment
- Where
- 2 sites in France
- Volunteers
- 200 people
- Sponsor
- Centre Oscar Lambret
Medulloblastoma Tumor
Evaluation of The Radioprotective Effect of 3D-Printed Intraoral Stents in Children With Brain Cancer.
Brain cancer patients undergoing radiotherapy may experience oral complications such as oral mucositis, gingival inflammation, plaque accumulation, radiation-induced caries, and reduced oral-health-related quality of life due to…
- Trial name
- NCT07715357
- Testing
- 3D printed intraoral stents.
- Volunteers
- 72 people
- Sponsor
- Ain Shams University
Cancer, NGS
Performance Indicators and Impact on the Care Pathway of Sequencing on the SeqOIA and AURAGEN (Seqogen) Platforms for Oncology Patients
As part of the French Genomic Medicine Plan 2025 (FGM), the SeqOIA and AURAGEN platforms were selected to perform high-throughput genomic sequencing.
- Conditions
- Cancer, NGS, Tumor, RARE DISEASE
- Trial name
- SONCO (NCT07147465)
- Where
- 3 sites in France
- Volunteers
- 3,149 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Exercise Behavior, Multiple Myeloma
Exercise Phenotyping Prior to Chemotherapy in Newly Diagnosed Multiple Myeloma (MM-Exercise)
MM-Exercise is a prospective, single-centre, observational pilot study of patients with newly diagnosed multiple myeloma who have not yet started chemotherapy and whose resting echocardiogram is unremarkable or only mildly…
- Trial name
- MM-Exercise (NCT07851493)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Technical University of Munich
PICC Line Placement, Tip Location
IC ECG Combined With Ultrasound Bubble Test for PICC Tip Positioning Among Oncology Adults: A Three Arm Randomized Controlled Trial
The goal of this clinical trial is to learn if using IC-ECG together with ultrasound works better than either method alone to identify the tip position of a PICC in adults with cancer.
- Trial name
- NCT07888400
- Testing
- Combined IC-ECG and Ultrasound PICC Tip Location Technique, IC-ECG PICC Tip Location Technique, Ultrasound PICC Tip Location Technique
- Where
- China
- Volunteers
- 267 people
- Sponsor
- Sun Yat-sen University
Sars-CoV2, Cancer
Prospective Analysis of Morbi-mortality of Patients With Cancers in Active Phase of Treatment Suspected or Diagnosed of a SARS-CoV-2 Infection
National multicentre epidemiological study to describe retrospectively and prospectively the clinical outcomes of patients with a suspected coronavirus infection (either confirmed or not) while receiving a medical treatment for…
- Trial name
- ONCOVID-19 (NCT04363632)
- Where
- 18 sites in France
- Volunteers
- 1,231 people
- Sponsor
- Centre Leon Berard
Head and Neck Cancer
Docetaxel and Capecitabine for First Line Treatment of Metastatic Squamous Cell Carcinoma of the Head & Neck
Recent progress in treatment of recurrent/metastatic SCCHN has been made with the introduction of the taxanes. Docetaxel as a single agent has a response rate of 22-42% and 17% in patients with recurrent disease.
- Trial name
- NCT00216138
- Testing
- Docetaxel, Capecitabine, Premedication
- Where
- 18 sites in United States
- Volunteers
- 19 people
- Sponsor
- Hoosier Cancer Research Network
Oncology, Sexual Health
Support of the Sexual Health in Oncology
Implementation of sexual health support program in oncology department. This program is organized in 3 axes. One is to inform the side effects of treatment on sexual health.
- Trial name
- NCT03166774
- Testing
- Program of support of the sexual health
- Sponsor
- Fondation Hôpital Saint-Joseph
Anxiety, Signs and Symptoms
Effectiveness of a Music Therapy Intervention in Cancer Patients Undergoing Active Treatment at the Jaén University Hospital: a Non-randomized Controlled Trial.
A cancer diagnosis and its clinical progression can cause patients physical, psychological, emotional, social, and spiritual distress.
- Conditions
- Anxiety, Signs and Symptoms, Oncologic Complications
- Trial name
- ECMONC (NCT07886658)
- Testing
- Music Therapy
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- University of Jaén
Urinary Bladder Tumour
Urinary Markers by SpectrosCopy: Diagnostic Aid in oncologY - Application to Urological Cancers
This study aims to evaluate the performance of vibrational spectroscopy (Infrared and Raman spectroscopy techniques) in bladder cancer diagnosis using urine samples.
- Trial name
- MUSCADE (NCT06087016)
- Testing
- Urine vibrational analysis
- Where
- France
- Volunteers
- 899 people
- Sponsor
- CHU de Reims
Oncology Patients
The Effect of Reiki on Hopelessness Level
This quasi-experimental study aims to examine the effect of Reiki on the level of hopelessness in oncology patients. The study was conducted at İzmir Tepecik Training and Research Hospital with 32 patients in both experimental…
- Trial name
- NCT06954506
- Testing
- Reiki Group
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Cardiac Toxicity, Lymphoma
Combination Chemotherapy With or Without Dexrazoxane in Treating Children With Hodgkin's Disease
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Chemoprotective drugs, such as dexrazoxane, may protect normal cells from the side effects of chemotherapy.
- Trial name
- NCT00005578
- Testing
- bleomycin sulfate, filgrastim, cyclophosphamide
- Where
- 63 sites in United States, Canada and 1 more
- Volunteers
- 219 people
- Sponsor
- Children's Oncology Group
Nursing, Gynecological Cancers
Effects of a Self-Regulation Based E-MOTE Program Delivered Via an AI-Assisted Robot and Supported by Mobile Platforms for Newly Diagnosed Gynecologic Cancer Patients
To evaluate the effectiveness of the E-MOTE Emotional Care Program, delivered through the Kebbi robot and the LINE Official Account, for patients newly diagnosed with gynecologic cancer undergoing surgery.
- Conditions
- Nursing, Gynecological Cancers, Psycho-Oncology
- Trial name
- NCT07745478
- Testing
- E-MOTE group
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Bone Sarcoma
Exercise Intervention for Bone Tumor Patients
The proGait-study is a two-arm exercise intervention study for AYA-patients with lower extremity tumor endoprosthesis in the follow-up care.
- Trial name
- proGAIT (NCT04963517)
- Testing
- Exercise therapy, Information
- Where
- Germany
- Volunteers
- 11 people
- Sponsor
- Universität Duisburg-Essen
Leukemia, Lymphoma
Interferon Alfa in Treating Children With HIV-Related Cancer
RATIONALE: Interferon alfa may interfere with the growth of cancer cells. PURPOSE: Phase II trial to study the effectiveness of interferon alfa in treating children with an HIV-related cancer including leukemia, non-Hodgkin's…
- Conditions
- Leukemia, Lymphoma, Unspecified Childhood Solid Tumor, Protocol Specific
- Trial name
- NCT00002621
- Testing
- recombinant interferon alfa
- Where
- 10 sites in United States, Canada and 2 more
- Volunteers
- 8 people
- Sponsor
- Children's Oncology Group
Cancer, Emergencies
Pro-active Monitoring of Vital Signs in Oncology Patients Using a Smartwatch
The goal of this single center prospective observational study is to determine the effect of chemotherapy on (the change in) vital parameters.
- Trial name
- PROGRESS (NCT06680778)
- Testing
- Proactive Monitoring
- Where
- Netherlands
- Volunteers
- 175 people
- Sponsor
- Erasmus Medical Center
Neurosurgery, Neurovascular
Intra-operative Hyperspectral Imaging in Neurosurgery
Brain surgery operations include brain tumour removal and blood vessel procedures. Each year in the UK, approximately 70,500 patients are diagnosed with a brain tumour, 5,000 of whom undergo surgery.
- Conditions
- Neurosurgery, Neurovascular, Neuro-Oncology
- Trial name
- NeuroHSI (NCT05294185)
- Where
- United Kingdom
- Volunteers
- 81 people
- Sponsor
- King's College London
Pediatric Cancer, Leukemia
Enrollment on the Childhood Cancer Research Network (CCRN) of the Children's Oncology Group
The Children's Oncology Group has established a research network, the Childhood Cancer Research Network (CCRN), to collect information about children with cancer and other conditions that are benign but involve abnormal cell…
- Conditions
- Pediatric Cancer, Leukemia, Sarcoma, Brain Tumors
- Trial name
- NCT01117168
- Where
- United States
- Volunteers
- 57,816 people
- Sponsor
- Children's Oncology Group
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