Clinical trials: Oncologic
Smoking Cessation and Lung Cancer
Study of Psychopathological Characteristics of Patient Smoking in Thoracic Oncology
Persistent smoking after lung cancer has been the subject of medical, therapeutic and epidemiological publications for twenty years of research.
- Trial name
- NCT01955057
- Testing
- Research interviews, Tests (Fagerström, Q-MAT, H.A.D.S, SCL 90-R), Projective methods (Thematic apperception Test, Rorschach)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
Cancer-related Pain, Pain Assessment
Developing a Multimodal Cancer Pain Database to Support AI-Based Automatic Pain Assessment
The goal of this observational study is to collect short video and sound recordings of people with cancer to create a secure database that can be used in future research to develop an artificial intelligence (AI) tool for pain…
- Conditions
- Cancer-related Pain, Pain Assessment, Artificial Intelligence (AI), Oncology
- Trial name
- SENSAI-DBD (NCT07262632)
- Testing
- Audiovisual and questionnaire-based data collection (once), Audiovisual and questionnaire-based data collection (consecutive)
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Dr. Mark Mulder
Metastasis
A Study Evaluating Safety and Therapeutic Activity of THOR-707 in Adult Subjects With Advanced or Metastatic Solid Tumors (THOR-707-101)
Primary Objectives: Evaluate the safety and tolerability of THOR-707 as a single agent and as a combination therapy (identify Dose Limiting Toxcitiy (DLTs) in Cohorts A, B, C, D, and G, and adverse events (AEs)/serious adverse…
- Trial name
- HAMMER (NCT04009681)
- Testing
- THOR-707, Checkpoint inhibitor, anti-EGFR antibody
- Where
- 24 sites in United States, Argentina and 4 more
- Volunteers
- 175 people
- Sponsor
- Synthorx, Inc, a Sanofi company
Breast Cancer, Gynecologic Cancer
Mobile App Postoperative Home Monitoring After Enhanced Recovery Oncologic Surgery
This study will assess whether the implementation of a combination of ERAS (Enhanced Recovery After Surgery) protocols and postoperative followup via a smartphone app can offer 1) improved patient satisfaction, 2) virtual patient…
- Trial name
- ERAS-OncoRe (NCT03456167)
- Testing
- RecoverWell mobile app for follow-up care
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Alberta Health Services, Calgary
Oncology, Nausea and Vomiting Chemotherapy-Induced
The Effect of Using Interactive Mobile Application for the Management of Chemotherapy- Induced Nausea and Vomiting in Children
The aim of this study was to develop an interactive mobile application and to investigate the effect of this application on the management of nausea and vomiting symptoms by using it during chemotherapy treatment.
- Conditions
- Oncology, Nausea and Vomiting Chemotherapy-Induced, Pediatric Cancer, Mobile Application
- Trial name
- NCT04693832
- Testing
- 5inD
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Trakya University
Cancer, Immune-related Adverse Event
Immune-Related Adverse Events and Associated Biomarkers in Patients Receiving Cancer Immunotherapy
The purpose of this project is to collect body samples like blood and tissue and health information from people receiving immune-based treatment for cancer.
- Trial name
- IMBARC (NCT06089967)
- Testing
- Medical chart review
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Duke University
Oncologic Disease, Hematologic Diseases
Molecular Characterizazion and Biological Samples Centralisation of Patients Affected by Oncoematolofic Pathology
Currently, the molecular characterization of onco-hematological, onco-immunological and hematological diseases, at onset or in relapse, of patients with suspected diagnosis afferent to the CROP centers, is done through…
- Trial name
- NCT06304194
- Testing
- Analysis of biological samples
- Where
- 3 sites in Italy
- Volunteers
- 340 people
- Sponsor
- Meyer Children's Hospital IRCCS
Colon Cancer, Gastric Cancer
Integrated Care Pathway in Oncology (PASSION)
A centralized unit for integrated management of care pathway in Oncology has been created. This unit settles the patients' appointments (biopsy, intravenous device, chemotherapy, imaging, oncologist...).
- Conditions
- Colon Cancer, Gastric Cancer, Pancreatic Cancer, Thoracic Neoplasms
- Trial name
- PASSION (NCT04235556)
- Testing
- Care pathway unit
- Where
- France
- Volunteers
- 1,800 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
CANCER
Clinical Benefits of Preoperative Nutrition Support With Enteral Immune-enhancing Formulas in Surgical Oncology
After surgical treatment, numerous trials using early postoperative enteral or parenteral nutritional support have been attempted, in order to reduce morbidity and mortality.
- Trial name
- NCT01032512
- Testing
- SUPPORTAN + GLUTAMINE PLUS, NO PREOPERATIVE NUTRITION SUPPORT
- Where
- Chile
- Sponsor
- University of Chile
Low Back Pain, Oncology
Digital Intervention for the Modification of Lifestyles (iGame)
The objective of the project is to analyze the clinical effectiveness of a gamifield mHealth application (iGAME) and developed in the context of lifestyle modification, but with the approach of the Behaviour Change Technique…
- Conditions
- Low Back Pain, Oncology, Depression, Sedentary Lifestyle
- Trial name
- NCT04019119
- Testing
- Digital intervention
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- University of Malaga
Urothelial Carcinoma, Head and Neck Cancer
MAGE-A10ᶜ⁷⁹⁶T for Urothelial Cancer, Melanoma or Head and Neck Cancers
This Phase 1 study is designed as a cell dose escalation trial in HLA-A*02:01 and HLA-A*02:06 subjects with MAGE-A10 positive urothelial, melanoma or head and neck tumors.
- Conditions
- Urothelial Carcinoma, Head and Neck Cancer, Melanoma, Bladder Urothelial Carcinoma
- Trial name
- NCT02989064
- Testing
- Autologous genetically modified MAGE A10ᶜ⁷⁹⁶T cells
- Where
- 11 sites in United States, Canada and 1 more
- Volunteers
- 10 people
- Sponsor
- Adaptimmune
Radiation Toxicity, MRI Simulated Positioning
A Novel Target Delineation Scheme in High-grade Glioma Patients: a Randomized Single-blind Clinical Trial
The main question it aims to answer are: 1. whether the new target delineation scheme can improve Progression-free Survival 2. whether it can reduce the incidence of radiation complications in high-grade glioma patients.
- Conditions
- Radiation Toxicity, MRI Simulated Positioning, High Grade Glioma, Progression-free Survival
- Trial name
- NCT06215495
- Testing
- reduced target volume, EORTC (European organisation for research and treatment of cancer) target volume
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Zhujiang Hospital
Breast Cancer
Four Conversations RCT
The purpose of this study is to see whether patients with metastatic breast cancer, their caregivers, and their healthcare providers can improve in shared decision making (SDM) and preparedness around end of life (EOL) planning…
- Trial name
- NCT02944344
- Testing
- Four Conversations
- Where
- United States
- Volunteers
- 357 people
- Sponsor
- Duke University
Cancer
CRQ Survey Study: Clinical Research Questionnaire of Oncology Patients - A Nationwide Survey
This is a translational, multicentre questionnaire study. The study design follows that of a cross sectional, quantitative research approach. Data collection will involve self-administered, paper-based questionnaires.
- Trial name
- NCT02836392
- Testing
- Questionnaire
- Where
- 14 sites in Ireland
- Volunteers
- 1,000 people
- Sponsor
- Cancer Trials Ireland
Pediatric Cancer
Immune Function and Response to Vaccination After Cancer Therapy in Pediatric Patients
Pediatric cancer survivors have increased infection-related morbidity and mortality. This study will evaluate immune dysfunction following cancer directed systemic therapy completion, with attention to clinical relevance and…
- Trial name
- NCT04948619
- Testing
- Vaccine
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Wake Forest University Health Sciences
Neoplasms, Nursing Caries
Nurse-Led Electronic Patient-Reported Outcome System to Improve Quality of Life in Chemotherapy Patients
Chemotherapy often causes burdensome symptoms that affect daily life and reduce patients' quality of life. This study aims to test whether an information-based symptom management program can help cancer patients better manage…
- Trial name
- NURSE-PRO (NCT07144449)
- Testing
- Nurse-Led ePRO System, Usual Care
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- CHIAO-CHI KUAN
Endometrial Cancer
Trial Between Two Follow up Regimens With Different Test Intensity in Endometrial Cancer Treated Patients
This study aims to compare two different follow up regimens with different test intensity in endometrial cancer treated patients.
- Trial name
- TOTEM (NCT00916708)
- Testing
- Intensive/Low-Risk follow up (IA G1; IA G2), Intensive/High-Risk follow up (≥ IA G3), Minimalist/Low-Risk follow up (IA G1; IA G2)
- Where
- Italy
- Volunteers
- 1,884 people
- Sponsor
- Azienda Ospedaliera San Giovanni Battista
Breast Cancer, Ductal Carcinoma In Situ, DCIS
Areola Preservation in NSM With Nipple Involvement
Background: During nipple-sparing mastectomy (a surgery that removes breast tissue but keeps the nipple and areola), doctors test the tissue behind the nipple right away.
- Conditions
- Breast Cancer, Ductal Carcinoma In Situ, DCIS, Invasive Breast Carcinoma
- Trial name
- APRESERVE-1 (NCT07544134)
- Testing
- Areola-Preserving Nipple-Sparing Mastectomy with Immediate Nipple Reconstruction
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Skin Toxicity
Novel Skin Care for Chemotherapy- Related Dermatologic Toxicities
Notwithstanding the continuous progress in cancer treatment, patients with cancer still have to cope with quality of life (QoL) - impairing complications.
- Trial name
- ChemoSkin (NCT04929847)
- Testing
- Self-prepared emollient
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Jessa Hospital
Psycho-Oncology, Visceral Cancer
Optimized Psycho-oncological Care Through an Interdisciplinary Care Algorithm
Adequate, needs-oriented psycho-oncological care contributes to reducing the burden on cancer patients and their relatives and to improving the quality of life.
- Conditions
- Psycho-Oncology, Visceral Cancer, Screening, Psychosocial Stressor
- Trial name
- OptiScreen (NCT04638699)
- Testing
- OptiScreen training
- Where
- Germany
- Volunteers
- 900 people
- Sponsor
- Hannover Medical School
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