Clinical trials: Oncologic
Colorectal Cancer
Implementing Preemptive Pharmacogenomic Testing for Colorectal Cancer Patients in a Community Oncology Clinic
Pharmacogenomics (PGx) studies the interactions between an individuals genes and medications. PGx testing identifies genes within an individual that may affect treatment, efficacy, and toxicity of drugs.
- Trial name
- CRCPGx (NCT03187184)
- Testing
- OneOme RightMed®
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Essentia Health
Esophageal Neoplasms
The Predictive Value of CT-PET in Esophageal Cancer
A major focus of research in oncology is to identify patients who, following induction therapy, have a complete pathologic response, presenting opportunities for novel trials, including extended therapy or non-operative…
- Trial name
- NCT02385604
- Where
- Ireland
- Volunteers
- 250 people
- Sponsor
- St. James's Hospital, Ireland
Palliative Care, Cost and Cost Analysis
Palliative Care Costs for Outpatient Setting Management in Catalunya
Cost-of-illness studies in palliative care (PC) are a growing area of interest in health economics activity. They are, in part, stakeholders' basis for deciding the allocation of the scarce public and private economic resources.
- Conditions
- Palliative Care, Cost and Cost Analysis, Outpatient
- Trial name
- CoCPAC (NCT05412784)
- Volunteers
- 100 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Multiple Myeloma
A Phase 1 Study Evaluating CPI-0610 in Patients With Previously Treated Multiple Myeloma
Open-label, sequential dose escalation and expansion study of CPI-0610 in patients with previously treated multiple myeloma. CPI-0610 is a small molecule inhibitor of bromodomain and extra-terminal (BET) proteins.
- Trial name
- NCT02157636
- Testing
- CPI-0610
- Volunteers
- 30 people
- Sponsor
- Constellation Pharmaceuticals
Gastroenteropancreatic Neuroendocrine Tumors
Community-based Neuroendocrine Tumor (NET) Research Study
The purpose of this trial is to assess time to disease progression of patients with locally advanced or metastatic gastroenteropancreatic neuroendocrine tumors treated with Lanreotide Depot.
- Trial name
- NCT02730104
- Where
- 12 sites in United States
- Volunteers
- 100 people
- Sponsor
- Ipsen
Cancer
Exercise and Cognitive Rehabilitation Interventions for Older Cancer Survivors
The objective of this study is to assess the preliminary effects of an integrated exercise and cognitive rehabilitation intervention (ECO), an exercise intervention (EXCAP), and a cognitive rehabilitation intervention (MAAT) as…
- Trial name
- ECO 2 (NCT07390045)
- Testing
- EXCAP, MAAT, ECO
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Rochester
Oncology & Epidemiology & Lung Cancer
Insights on Dissemination of Lung Cancer
In patients with resectable NSCLC treated with surgery alone or with surgery as part of a multimodal treatment; CTC, ctDNA, STAS, and lymph node micrometastasis levels will be evaluated to see if they are associated with…
- Trial name
- LUCID (NCT07476495)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Breast Cancer
TREATMENT AND MONITORING PATTERNS AND CLINICAL OUTCOMES IN PATIENTS RECEIVING PALBOCICLIB COMBINATION TREATMENT (WITH AI OR FULVESTRANT) FOR HR+/HER2- A/MBC IN A COMMUNITY ONCOLOGY SETTING.
This is a retrospective, observational study that will document the treatment and monitoring patterns and clinical outcomes of patients diagnosed with HR+/HER2- a/mBC who received Palbociclib combination therapy with aromatase…
- Trial name
- NCT04498481
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Pfizer
Stress, Wellbeing
Impact of Aromatherapy on Wellbeing and Relaxation in Gynae Oncology Patients Post Treatment
The goal of this pilot study is to learn if aromatherapy helps to reduce stress and improve relaxation and wellbeing in gynaecological cancer patients after they have finished their treatment for cancer.
- Conditions
- Stress, Wellbeing, Relaxation
- Trial name
- NCT06590077
- Testing
- Aromatherapy
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- University of Dublin, Trinity College
Pediatric Cancer
Pharmacogenomic Testing in Pediatric Hematology/Oncology Patients
Pharmacogenomic (PGx) testing involves analyzing variants of genes associated with drug metabolism, transport and medication targets.
- Trial name
- NCT06744712
- Testing
- Pharmacogenomic Testing
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Wake Forest University Health Sciences
Oncology
Automatized "Semi-Whole-Body"-MRI Protocol for Cancer Staging
The aims of this study are to evaluate the image quality and robustness of a whole-body MRI protocol by using an innovative partially automatic algorithm (DOT engine), that automatically optimizes protocol parameters depending on…
- Trial name
- NCT03648619
- Testing
- Semi whole-body MRI
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- Kantonsspital Baden
Neuroendocrine Tumors
Neuroendocrine Tumors of Old Patients in the West of France
Neuroendocrine cancer remains a poorly known entity. Comprehensive treatment is multidisciplinary involving surgery, radiological and nuclear medicine, and medical.
- Trial name
- TANGO (NCT03749681)
- Where
- France
- Volunteers
- 306 people
- Sponsor
- University Hospital, Brest
Advanced Cancer, Rare Diseases
Umbrella Study for Single Patient Treatments in Oncology
The purpose of this study is to collect data for assessing the improvement of the overall response rate for the overall cohorts and the proportion of patients accessing precision targeted therapy.
- Trial name
- UNIQUE (NCT06285500)
- Testing
- Patient-specific treatments
- Where
- Canada
- Volunteers
- 400 people
- Sponsor
- University Health Network, Toronto
Acute Lymphoblastic Leukemia, Acute Myeloblastic Leukemia
Pulmonary Function at Presentation and Follow-up in Hemato-Oncology 3-7 Years Old Children
The aim of this study was to investigate the occurrences of respiratory symptoms risk factors and abnormalities in lung function in young children (3-6 years old) with hemato-oncologic diseases at presentation (before treatment)…
- Conditions
- Acute Lymphoblastic Leukemia, Acute Myeloblastic Leukemia, Solid Tumors,, Hodgkin's Disease
- Trial name
- NCT00552825
- Where
- Israel
- Volunteers
- 35 people
- Sponsor
- Sheba Medical Center
Neoplasms
Effects of Laugh-yoga Intervention on Mood and Quality of Life Among Oncologic Patients in a Oncologic Clinic Setting.
Previous studies report low levels of mood and of quality of life among cancer patients. Laugh has been proved to improve mood and immune system function.
- Trial name
- NCT01156935
- Testing
- Laugh Yoga
- Volunteers
- 60 people
- Sponsor
- Wolfson Medical Center
Breast Cancer, Cardiotoxicity
Cardiotoxicity in Breast Cancer Patients Treated With Proton or Photon Radiotherapy: A RadComp Companion Study
This is a companion study to the "Pragmatic Randomized Trial of Proton vs Photon Therapy for Patients with non-Metastatic Breast Cancer Receiving Comprehensive Nodal Radiation: A Radiotherapy Comparative Effectiveness (RadComp)…
- Trial name
- NCT04361240
- Testing
- Proton vs Photon Radiation
- Where
- 6 sites in United States
- Volunteers
- 172 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Female Breast Cancer
Expectations and Side Effects of Endocrine Therapy in Women With Breast Cancer
The purpose of this study is to evaluate the role of patients' response expectations for nocebo side effects, quality of life and adherence during adjuvant endocrine treatment (AET).
- Trial name
- NCT02088710
- Testing
- Enhanced information about endocrine therapy
- Where
- Germany
- Volunteers
- 138 people
- Sponsor
- Philipps University Marburg
Elective Surgery for Any Digestive Cancer
Benefit of a Flash Dose of Corticosteroids in Digestive Surgical Oncology: a Randomized, Double Blind, Placebo-controlled Trial
Perioperative inflammation is harmful in cancer patients, namely in those undergoing surgery: it increases the risk of recurrence, decreases cancer survival, increases post-operative complications, and prolongs the time of…
- Trial name
- CORTIFRENCH (NCT03875690)
- Testing
- Injection of methylprednisolone, Injection of sodium chloride, Blood samples
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Acute Lymphoblastic Leukemia, Pediatric
Parental Perception of Their Child's Emotional Quality of Life in Paediatric Oncology Before and After "Magic Massages"
Rationale: In France, 1,850 cases of cancer are diagnosed in children every year (28% of leukaemia). Despite a cure rate of 83% (all cancers combined), treatment remains a major burden.
- Trial name
- MASSAYA (NCT06107478)
- Testing
- Self-report questionnaires (only for parents), Interview (only for parents), Clinical data collection (only concerning Children)
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Centre Leon Berard
Cancer, Brain Tumor, Primary
A Tailored Exercise Oncology Program for Neuro-Oncology Patients
Background: Exercise, or physical activity, is beneficial for all cancer survivors. Despite this knowledge, there is generally a gap between the evidence and practice.
- Trial name
- ACE-Neuro (NCT04831190)
- Testing
- Tailored Exercise Intervention
- Where
- 4 sites in Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Calgary
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