Clinical trials: Oncologic
Gynecologic Cancer, Breast Cancer
Web-based Family History Tool
The purpose of this pilot study is to determine if a web-based tool that collects family health history is useful for patients being seen in a gynecologic oncology office setting.
- Conditions
- Gynecologic Cancer, Breast Cancer, BRCA1 Mutation, BRCA2 Mutation
- Trial name
- Progeny (NCT04890327)
- Testing
- Web-based family health history tool
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Breast Cancer
NAC Sparing Mastectomy After Neo-adjuvant Chemotherapy
Nipple areolar-complex (NAC) sparing mastectomy, extending the concept of skin-sparing mastectomy, allows to leave the nipple-areola complex intact and to provide a better cosmetic result.
- Trial name
- NCT02471742
- Testing
- NAC-sparing mastectomy, conventional mastectomy
- Where
- Italy
- Volunteers
- 573 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Oncologic Disease, Hematologic Diseases
Molecular Characterizazion and Biological Samples Centralisation of Patients Affected by Oncoematolofic Pathology
Currently, the molecular characterization of onco-hematological, onco-immunological and hematological diseases, at onset or in relapse, of patients with suspected diagnosis afferent to the CROP centers, is done through…
- Trial name
- NCT06304194
- Testing
- Analysis of biological samples
- Where
- 3 sites in Italy
- Volunteers
- 340 people
- Sponsor
- Meyer Children's Hospital IRCCS
Oncology, MET Gene Amplification
Sym015 (Anti-MET) in Patients With Advanced Solid Tumor Malignancies
This is the first study to test Sym015 in humans. The primary purpose of this study is to see if Sym015 is safe and effective for patients with advanced solid tumor malignancies without available therapeutic options.
- Conditions
- Oncology, MET Gene Amplification, NSCLC, MET Gene Mutation
- Trial name
- NCT02648724
- Testing
- Sym015
- Where
- 27 sites in United States, Denmark and 4 more
- Volunteers
- 57 people
- Sponsor
- Symphogen A/S
Osteoarthritis Shoulder, Rheumatoid Arthritis
Exactech Humeral Reconstruction Prosthesis of Shoulder Arthroplasty PMCF (HRP)
The objective of this study is to collect and evaluate long-term clinical outcomes data in order to better understand the safety and performance of the Equinoxe Humeral Reconstruction Prosthesis in shoulder arthroplasty over…
- Conditions
- Osteoarthritis Shoulder, Rheumatoid Arthritis, Oncology
- Trial name
- HRP (NCT05615246)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Exactech
Mobilization of Hematopoietic Stem Cells (HSC) to Peripheral Blood (PB), Hematopoetic Stem Cell Transplantation
G-CSF Combined With IL-11 on Hematopoietic Reconstitution After Autologous Hematopoietic Stem Cell Transplantation
Autologous hematopoietic stem cell transplantation(auto-HSCT) plays an important role in treating hematologic malignancies. Mobilization and collection of peripheral blood stem/progenitor cells is the key to successful autologous…
- Conditions
- Mobilization of Hematopoietic Stem Cells (HSC) to Peripheral Blood (PB), Hematopoetic Stem Cell Transplantation, Hemato-oncologic Patients
- Trial name
- NCT07362810
- Testing
- G-CSF+IL-11, G-CSF Granulocyte-Colony Stimulating Factor
- Where
- 7 sites in China
- Volunteers
- 224 people
- Sponsor
- Fudan University
Lung Cancer, Surgery
Nutritional Therapy Enriched With Omega-3 in Patients With Lung Resection
The aim of this study is to analyze the effect of enriched formula with omega-3 in the 30-day incidence infection and inflammatory response following lung resection surgery in lung cancer patients.
- Trial name
- NCT06531460
- Testing
- Fish oil enteral supplementation, Fish oil oral supplementation, Enteral nutrition without fish oil
- Where
- Mexico
- Volunteers
- 310 people
- Sponsor
- National Institute of Respiratory Diseases, Mexico
Gynecologic Cancer
Mind-body Online Therapy in Gynecological Oncology
In this randomized-controlled two-arm monocentric study with three measurement time points, the effectiveness and feasibility of an internet-based, therapist-guided mind-body self-help intervention for gynecological cancer…
- Trial name
- NCT05313724
- Testing
- Mind-Body Online Therapy
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Katja Haemmerli Keller
Lung Cancer
Empathic Communication Skills (ECS) Training
Research indicates that perceived stigma within medical encounters is prevalent and problematic for lung cancer patients' well-being and quality of cancer care.
- Trial name
- NCT05456841
- Testing
- Empathic Communication Skills (ECS) training, Standard of Care participant interaction
- Where
- 12 sites in United States
- Volunteers
- 1,232 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Oncology, Solid Tumors
Study of Avelumab-M3814 Combinations
The main purpose of the study was to evaluate a safe, tolerable recommended Phase II dose (RP2D) and/or the maximum tolerated dose (MTD) of M3814 when given in combination with avelumab with and without radiotherapy in…
- Trial name
- NCT03724890
- Testing
- M3814, Avelumab, Radiotherapy
- Where
- 8 sites in United States
- Volunteers
- 57 people
- Sponsor
- EMD Serono Research & Development Institute, Inc.
Malignant Neoplasm of Breast
Phase 1 Study to Evaluate the Effect of DS-8201a on the QT/QTc Interval and Pharmacokinetics in HER2-Expressing Breast Cancer
This study will look at the effect on the QTc interval and pharmacokinetics after multiple dosing in subjects with HER2-expressing metastatic and/or unresectable breast cancer.
- Trial name
- NCT03366428
- Testing
- DS-8201a
- Where
- 7 sites in Japan
- Volunteers
- 51 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Cancer, Neoplams
Effect of Pecha Kucha-Based Education on Symptom Management and Quality of Life in Patients Receiving Chemotherapy
This randomized controlled study aims to evaluate the effect of education delivered using the PechaKucha method on symptom management and quality of life in patients receiving chemotherapy.
- Trial name
- NCT07769931
- Testing
- PechaKucha-Based Symptom Management Education, Routine/Standard Patient Education
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Istanbul Aydın University
Cancer, Lymphoma
A Study of PNT2258 in Patients With Advanced Solid Tumors
This study is sponsored by Sierra Oncology, Inc. formerly ProNAi Therapeutics, Inc. The purpose of this research study is to evaluate the safety of the investigational drug PNT2258 in patients with advance tumors and see how it…
- Conditions
- Cancer, Lymphoma, Prostate Cancer, Melanoma
- Trial name
- NCT01191775
- Testing
- PNT2258
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Sierra Oncology LLC - a GSK company
Lung Carcinoma
Supportive Care Needs of Bronchial Cancer Patients in Active Treatment: A Descriptive Study in Outpatient Oncology
Bronchial cancer is a major oncological pathology, representing the leading cause of cancer death in France. Supportive oncological care (SOS) is defined as all the care and support necessary for patients throughout their…
- Trial name
- NCT06832592
- Where
- France
- Volunteers
- 100 people
- Sponsor
- L'hôpital Nord-Ouest - Villefranche Villefranche sur Saône
Advanced Non Small Cell Lung Cancer, Advanced (Inoperable) Non Small Cell Lung Cancer
AZD9291 First Time In Patients Ascending Dose Study
This study will treat patients with advanced NSCLC who have already received at least one course of specific anti-cancer treatment but the tumour has started to re-grow following that treatment.
- Trial name
- AURA (NCT01802632)
- Testing
- AZD9291
- Where
- 45 sites in United States, Australia and 8 more
- Volunteers
- 603 people
- Sponsor
- AstraZeneca
Estrogen Receptor Positive Breast Cancer
[18F]Fluoroestradiol-PET/CT Companion Imaging Study to the FORESEE Trial
This protocol is a companion imaging study that will add FES-PET/CT imaging to the FORESEE trial at HCI. This study will establish the feasibility of using FES-PET/CT imaging to guide therapeutic decision making for functional…
- Trial name
- NCT04727632
- Testing
- [18F]Fluoroestradiol (FES) PET/CT
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Utah
Pediatric Cancers
Palliative Care and Symptom Management for the Pediatric Oncology Patient
The goal of this study is to learn about the communication, decision-making, symptom management, emotional adjustment, and spiritual needs of parents and pediatric patients treated at the Children's Cancer Hospital at M. D.
- Trial name
- NCT00675467
- Testing
- Focus Group - Parent/Caregiver, Focus Group - Pediatric Patient
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- M.D. Anderson Cancer Center
Solid Tumor, Adult
A Study to Assess AXN-2510 Treatment in Adult Patients With Advanced Solid Tumors
The goal of this clinical trial is to learn more about the side effects and best dose of AXN-2510 in adults with advanced solid tumors.
- Trial name
- NCT07159828
- Testing
- AXN-2510
- Where
- 7 sites in United States
- Volunteers
- 3 people
- Sponsor
- Axion Bio, Inc
Patient Having a Cancer
Assessments and Recommendations for the Implementation of Advance Directives in Oncology
Legitimized by the Leonetti law of April 22, 2005, advance directives (AD) appear in various places of care that alongside the end of life, and even tend to be generalized to all areas related to health care in general.
- Trial name
- DA (NCT02634632)
- Testing
- Choosing to write advance directives
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Oncology, Quality of Life
Long-term Follow-up and Quality of Life of Patients Treated With Anticancer Drugs
Currently, aspects related to the effects of anticancer treatments and the quality of life of patients and their needs are still poorly documented at the Rafael Institute.
- Conditions
- Oncology, Quality of Life, Symptoms and Signs
- Trial name
- THERAPINNOV (NCT06317714)
- Testing
- questionnaires
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Institut Rafael
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