Clinical trials: Oncologic
Paediatric Oncology, Nurses
RCT to Evaluate the Efficacy of the NSSCEP in Reducing Burnout Among Jordanian Pediatric Oncology Nurses
The goal of this clinical trial is to learn if the Nurses' Stress Self-Care Educational Program (NSSCEP) can reduce burnout and occupational stress in Jordanian pediatric oncology nurses.
- Conditions
- Paediatric Oncology, Nurses, Burnout, Occupational Stress
- Trial name
- NSSCEP (NCT07175103)
- Testing
- Nurses' Stress Self-Care Educational Program (NSSCEP), General Technical Skills Program
- Where
- Jordan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Localized Resectable Tumor, MSI/dMMR
Immunotherapy in MSI/dMMR Tumors in Perioperative Setting.
This trial is a multicenter, 3-cohort, prospective, Phase II trial conducted in patients with untreated resectable MSI/dMMR carcinomas and aiming to evaluate the safety and the efficacy of ICI (immune checkpoint inhibitor) as…
- Trial name
- IMHOTEP (NCT04795661)
- Testing
- Pembrolizumab
- Where
- 18 sites in France
- Volunteers
- 240 people
- Sponsor
- Centre Leon Berard
Oral Mucositis
Oral Care With Propolis in Pediatric Oncology Patients
According to the data from the World Health Organization, approximately 14 million people are diagnosed with cancer every year, and this number is expected to increase further in the next 10 years.
- Trial name
- NCT05400031
- Testing
- propolis
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Izmir Katip Celebi University
Cancer, Oncology
Intelligent Electric Bicycle for Health (VELIS) to Optimize the Return to Physical Activity for Oncology Patients
The purpose of this pilot study is to encourage oncology patients to continue effort retraining after their release from rehabilitation and recuperative care facilities with physical activity sessions and therapeutic education…
- Trial name
- NCT03340857
- Testing
- Intelligent electric bicycle (VELIS) sessions
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Fondation Audavie
Neoplasm Metastasis
Study of DS-8201a for Participants With Advanced Solid Malignant Tumors
HER2-positive cancer is a cancer that tests positive for a protein called human epidermal growth factor receptor 2 (HER2). HER2 promotes the growth of certain cancer cells.
- Trial name
- NCT03383692
- Testing
- DS-8201a, Ritonavir, Itraconazole
- Where
- 10 sites in Japan, South Korea and 1 more
- Volunteers
- 40 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Cancer (Solid Tumors), Geriatric Oncology
TRTRM (ACTTOP) -Guided Dosing Strategy in Older Patients With Cancer
Older adults receiving systemic cancer treatments are at increased risk of developing severe treatment-related toxicities (TRT).
- Trial name
- NCT07484932
- Testing
- TRTRM-guided risk-stratified treatment strategy
- Where
- Hong Kong
- Volunteers
- 400 people
- Sponsor
- The University of Hong Kong
Neoplasms
Counting Steps! Integration of Objectively Assessed Physical Activity and Fitness With Smartphones in Clinical Oncology Practice.
Rationale: Optimal selection of patients with cancer eligible for a clinical trial, is of utmost importance, but can be very difficult.
- Trial name
- NCT03493672
- Testing
- Objective measurement of physical activity and fitness
- Where
- Netherlands
- Volunteers
- 135 people
- Sponsor
- Amsterdam UMC, location VUmc
Carcinoma, Transitional Cell (RENI)
Prognostic Value of Performance Scores in Patients Undergoing Surgery for Upper Tract Urothelial Carcinoma
Aim: to comprehensively evaluate the prognostic value of preoperative ECOG-PS scores and ASA scores in patients undergoing radical nephroureterectomy (RNU) for upper tract urothelial carcinoma. Methods: multicentered cohort study
- Trial name
- NCT06305130
- Testing
- No intervention
- Volunteers
- 2,515 people
- Sponsor
- Kaohsiung Medical University
Snoezelen, Pediatric Cancer
Proof-of-Concept Study of the SNOEZELEN Device on Anxiety Symptoms in Patients Hospitalized for Chemotherapy in a Pediatric Oncology Department
The goal of this clinical trial is to evaluate whether the Snoezelen multisensory relaxation approach can reduce anxiety symptoms in children and adolescents aged 8 to 17 years hospitalized for chemotherapy in a pediatric…
- Conditions
- Snoezelen, Pediatric Cancer, Symptomatologie Anxieuse, Chimiothérapie
- Trial name
- SNOOZE (NCT07202507)
- Testing
- self-report questionnaires, research interviews
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Oscar Lambret
Undernutrition, Cancer
Management of Malnutrition in Oncogeriatrics
In France, undernutrition affects almost three million people, a third of whom are over 70 (Diagnosing undernutrition earlier in the elderly aged 70 and over, n.d.).
- Trial name
- NCT06425315
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Hospices Civils de Lyon
Cardiac Inflammation
Heart Analysis in GATED-PET in Patients Having a Gallium-68-DOTATOC PET/CT Exam for Oncology Indication
Gallium-68-DOTATOC binds primarily with high affinity to somatostatin subtype 2 (SSTR2) receptors and these somatostatin receptors are also overexpressed on inflammation cells when activated.
- Trial name
- GATEDOTA (NCT06467968)
- Testing
- Cardiac ECG-gated PET imaging will added
- Where
- France
- Volunteers
- 99 people
- Sponsor
- Central Hospital, Nancy, France
Granulocyte Colony-Stimulating Factor, Chemotherapy-induced Neutropenia
Starting Granulocyte Colony-Stimulating Factor at 1 Day vs 3 Days Following Chemotherapy in Pediatric Cancer Patients
Chemotherapy places patients at an increased risk of infection. A medication called granulocyte colony-stimulating factor is given as a daily injection in order to help decrease the risk of infection.
- Conditions
- Granulocyte Colony-Stimulating Factor, Chemotherapy-induced Neutropenia, Chemotherapy-Induced Febrile Neutropenia, Pediatric Cancer
- Trial name
- NCT03823950
- Testing
- Granulocyte Colony-Stimulating Factor
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Mississippi Medical Center
Lymphoma, Non-Hodgkin
A Phase I, Dose-Escalation Study to Assess the Safety and Biological Activity of Recombinant Human Interleukin-18
The purpose is to identify a dose of SB-485232 which is safe, tolerable and effective when used in combination with Rituximab in patients with non-Hodgkin's lymphoma (NHL).
- Trial name
- NCT00500058
- Testing
- SB-485232, Rituximab
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- GlaxoSmithKline
Metastatic Colon Adenocarcinoma, Metastatic Colon Cancer
xDRIVE in Metastatic Colorectal Cancer
The study aims to evaluate the clinical utility of the xDRIVE functional precision medicine + artificial intelligence (AI) platform in predicting treatment response for metastatic colorectal cancer (mCRC).
- Conditions
- Metastatic Colon Adenocarcinoma, Metastatic Colon Cancer, Metastatic Rectal Adenocarcinoma, Metastatic Rectal Carcinoma
- Trial name
- NCT06929338
- Testing
- Functional precision medicine
- Sponsor
- First Ascent Biomedical Inc.
Postoperative Delirium (POD), Gynecologic Cancers
Immunonutrition and Neuromonitoring for Postoperative Delirium in Gynecologic Oncology
Early postoperative delirium (POD) is a common and distressing neuropsychiatric complication frequently observed in elderly patients undergoing major surgical interventions, including radical and cytoreductive gynecologic…
- Conditions
- Postoperative Delirium (POD), Gynecologic Cancers, Malnutitrion
- Trial name
- NCT07877285
- Testing
- Preoperative Immunonutritional Scoring and Intraoperative Neuromonitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Pediatric Oncology
Effects of Resistance and Endurance Training in Pediatric Cancer Patients During Intensive Treatment Phase
The purpose of this study is to determine whether combined endurance and resistance training can improve muscle strength in children and adolescents with cancer during the intensive treatment phase.
- Trial name
- MUCKI (NCT02612025)
- Testing
- Exercise Training
- Where
- Germany
- Volunteers
- 35 people
- Sponsor
- Johannes Gutenberg University Mainz
Bladder Cancer, Muscle-Invasive Bladder Carcinoma
Clinical Trial to Evaluate Post-Operative Outcomes of Ureteral Stent vs Ureteral Stent Free Radical Cystectomy
Subjects will be randomized into 2 groups (stent or no stent) prior to radical cystectomy with ileal conduit urinary diversion (RCIC). They will follow the standard of care and be enrolled in the study for 12 months post-op.
- Conditions
- Bladder Cancer, Muscle-Invasive Bladder Carcinoma, Urothelial Carcinoma, Pelvic Malignancy
- Trial name
- NCT07234968
- Testing
- Ureteral Stent Placement, No Ureteral Stent, Indocyanine Green with Fluorescence Imaging
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- Thomas Jefferson University
Cirrhosis
Use of the French Healthcare Insurance Database
Hepatocellular carcinoma (HCC) has become the second most common cause of cancer death in the world, estimated responsible for nearly 745,000 deaths in 2012 (9.1% of all cancer deaths).
- Trial name
- SAMHEPAT (NCT02983968)
- Testing
- Description of the cirrhosis management
- Where
- France
- Volunteers
- 75,868 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Pediatric Cancer
Cope 360 App for Caregivers of Children With Cancer
To date, most caregiver focused interventions have been targeted at caregivers of adults with cancer, completely ignoring the unique needs of caregivers of children with cancer.
- Trial name
- NCT05112458
- Testing
- Cope 360 mobile health application, Usual care
- Volunteers
- healthy volunteers welcome
- Sponsor
- Indiana University
Childhood Cancer, Cancer
CANnabinoids in Pediatric ONCology
CANnabinoids in Pediatric ONCology is a randomized, double blind, adaptive clinical trial looking at the tolerability of cannabinoids in children with cancer across 3 Canadian children's hospitals.
- Trial name
- CAN-PONC (NCT05754840)
- Testing
- MPL-001, MPL-005, MPL-009
- Where
- 3 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of Manitoba
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