Clinical trials: Oncologic
Cancer and / or Hematological Malignancy, Anthracycline-induced Cardiotoxicity
BHF-COLLATE: UK Prospective, Multi-centre, Observational, Cardio-oncology Anthracycline Registry
The study aims to collect information on how cancer treatment affects heart health. This will include collecting baseline medical information, storing blood samples, recording cancer treatment, and analysing heart scans across…
- Trial name
- BHF-COLLATE (NCT07864467)
- Where
- 6 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- South Tees Hospitals NHS Foundation Trust
Ovarian Neoplasms, Uterine Neoplasms
Evaluation of Interactions and Group Processes in Multidisciplinary Tumor Boards in Gynecologic Oncology
Study Title Group Dynamics Evaluation in Gynecologic Multidisciplinary Tumor Boards - GOLD Study Background and Rationale Multidisciplinary Tumor Boards are central to complex oncologic decision-making.
- Trial name
- GOLD (NCT07645716)
- Testing
- Online Survey Assessment of Tumor Board Group Dynamics
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Oncology, Myeloid Leukemia, Acute
A Decisional Intervention for Older Adults With Acute Myeloid Leukemia and Their Caregivers
This is a multicenter randomized controlled trial that assesses the efficacy of a decisional intervention [University of Rochester-Geriatric Oncology assessment for Acute myeloid Leukemia (UR-GOAL)] compared to an attention…
- Conditions
- Oncology, Myeloid Leukemia, Acute, Cancer
- Trial name
- UR-GOAL RCT (NCT06697600)
- Testing
- UR-GOAL
- Where
- 4 sites in United States
- Volunteers
- 1,020 people
- Sponsor
- University of Rochester
Subjective Cognitive Complaints, Cancer
Emotional Freedom Techniques to Reduce Patient Reported Cognitive Complaints in Cancer Survivors
The aim of this study is to further validate the CDT as a screening tool for identifying elderly cancer patients in need of a more in-depth cognitive evaluation within comprehensive geriatric assessment (CGA) and to validate the…
- Trial name
- EMOTICON (NCT02771028)
- Testing
- Emotional Freedom Techniques
- Where
- 3 sites in Belgium
- Volunteers
- 121 people
- Sponsor
- General Hospital Groeninge
Left-sided Pancreatic Cancer, Ductal Adenocarcinoma
Oncologic Impact of Splenectomy-omitting Radical Pancreatectomy in Well-selected Left-sided Pancreatic Cancer
When distal pancreatectomy is carried out for left-sided pancreatic cancer, splenectomy is usually performed not only for margin-negative resection but also for effective clearance of the splenic hilar lymph nodes.
- Trial name
- NCT01875198
- Testing
- Radical Antegrade Modular Pancreatectomy with Splenectomy, Radical Antegrade Modular Pancreatectomy without splenectomy
- Where
- South Korea
- Volunteers
- 1 people
- Sponsor
- Yonsei University
Toxicity Due to Chemotherapy, Cancer Cachexia
Chemotherapy-related Toxicity, Nutritional Status and Quality of Life
Determine whether nutritional support with high protein ONS in adult oncologic patients in the first step of cancer cachexia - asymptomatic precachexia, influence on the toxicity of systemic therapy.
- Conditions
- Toxicity Due to Chemotherapy, Cancer Cachexia, Metastatic Colorectal Cancer, Quality of Life
- Trial name
- NCT02848807
- Testing
- NUTRIDRINK Compact Protein
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- University Clinical Centre, Gdansk
Cervical Cancer, Endometrial Cancer
Epidural Analgesia or Patient-Controlled Analgesia in Treating Patients Who Have Undergone Surgery for Gynecologic Cancer
RATIONALE: Giving pain medication into the space between the wall of the spinal canal and the covering of the spinal cord or giving it into a vein may help lessen pain caused by cancer surgery.
- Conditions
- Cervical Cancer, Endometrial Cancer, Fallopian Tube Cancer, Ovarian Cancer
- Trial name
- NCT00295945
- Testing
- fentanyl citrate, hydromorphone hydrochloride, ropivacaine hydrochloride
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of California, San Francisco
Prostate Cancer
Neoadjuvant Study of In-situ REIC/Dkk-3 in Prostate Cancer
This is a phase I neoadjuvant gene therapy followed by prostatectomy, open-label, dose-escalation trial for prostate cancer patients with high risk of local recurrence after radical prostatectomy.
- Trial name
- NCT01197209
- Testing
- Ad-REIC/Dkk-3
- Where
- United States
- Sponsor
- Momotaro-Gene Inc.
Pancreatic Cancer, Endoscopy
Plastic Stent Within a Lumen-Apposing Stent for Malignant Biliary Obstruction
There are doubts concerning the possible benefits derived from the insertion of double-pigtail plastic stents (DPS) within the lumen-apposing metal stents (LAMS) in the EUS-guided transmural biliary drainage (BD).
- Conditions
- Pancreatic Cancer, Endoscopy, Oncologic Disorders, Therapy Related Neoplasms
- Trial name
- LAMSpigBil (NCT04420039)
- Testing
- Endoscopic biliary transmural drainage
- Where
- 3 sites in Spain
- Volunteers
- 39 people
- Sponsor
- Hospital Universitari de Bellvitge
Early Stage Breast Carcinoma
Observational Trial on the Impact of Hypnose Used as a Sedation in Oncology Surgery in Breast Cancer
The investigators will compare the operated patients for a beginning breast cancer in the Hypnose arm and the patient in the classical general anesthesia arm.
- Trial name
- NCT03003611
- Testing
- hypnose sedation, general anesthesia
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Prostate Cancer, Prostate Cancer (Diagnosis)
Study of the Epidemiological, Clinical, Diagnostic, and Therapeutic Characteristics of Prostate Cancers in Algeria
The goal of this observational study is to describe the demographic, epidemiological, clinical, and outcome characteristics of patients with prostate cancer.
- Conditions
- Prostate Cancer, Prostate Cancer (Diagnosis), Prostate Cancer (Post Prostatectomy), Prostate Cancer Patients Treated by Radiotherapy
- Trial name
- CLIQQC (NCT07484971)
- Where
- 24 sites in Algeria
- Volunteers
- 2,000 people
- Sponsor
- Société Algérienne de Formation et Recherche en Oncologie
Low Risk Myelodysplastic Syndromes
Study of R289 in Patients With Lower-risk Myelodysplastic Syndromes (LR MDS)
Phase 1b Study of R289 in Patients with Lower-risk Myelodysplastic Syndromes (LR MDS)
- Trial name
- NCT05308264
- Testing
- R906289 Monosodium (R289 Na)
- Where
- 15 sites in United States
- Volunteers
- 86 people
- Sponsor
- Rigel Pharmaceuticals
Transitional Cell Carcinoma of the Bladder
Neoadjuvant Cisplatin, Gemcitabine, Sunitinib Malate + Radical Cystectomy for TCC
This trial will investigate the activity of sunitinib combined with cisplatin and gemcitabine followed by radical cystectomy in patients with Transitional Cell Carcinoma (TCC) of the Bladder.
- Trial name
- NCT00859339
- Testing
- Gemcitabine, Cisplatin, Sunitinib Malate
- Where
- 5 sites in United States, United Kingdom
- Volunteers
- 9 people
- Sponsor
- Noah Hahn, M.D.
Childhood Cancer
PET/MRI and PET/CT in Diagnosing Younger Patients With Cancer
This pilot clinical trial studies how well positron emission tomography (PET)/magnetic resonance imaging (MRI) works compared to PET/computed tomography (CT) in diagnosing younger patients with cancer.
- Trial name
- NCT02287636
- Testing
- fludeoxyglucose F 18, positron emission tomography, computed tomography
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Case Comprehensive Cancer Center
Breast Cancer, Mobile Community
Distress Reduction by Activity Tracking and Activity Enhancement by Mobile Support Group in Oncology
This study aims to investigate the effect of the formation of social networks using smartphones can help increase physical activity and reduce stress in survivors after breast cancer treatment surgery.
- Trial name
- DRAAGON (NCT03783481)
- Testing
- Mobile community, No Mobile community
- Where
- South Korea
- Volunteers
- 202 people
- Sponsor
- Asan Medical Center
Cancer
Implementation of a Return Home With a Hospitalization at Home or With a Home Health Care Provider From the Services of Oncopneumology, Oncology and Hematology of University Hospital of Strasbourg
Hospitalization at home is booming. It is designed to meet the demands of patients and their families to continue care at home. It partially solves the problem of the lack of places in the "long-term care" structures and allows…
- Trial name
- NCT03217864
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Colorectal Cancer
Efficacy and Safety of Simtuzumab (SIM) With FOLFIRI as Second Line Treatment in Colorectal Adenocarcinoma
The primary objective of this study is to compare the additive efficacy of SIM versus placebo in combination with leucovorin (folinic acid), irinotecan, and fluorouracil (FOLFIRI) as measured by improvement in progression-free…
- Trial name
- NCT01479465
- Testing
- Simtuzumab, Leucovorin, Irinotecan
- Where
- 109 sites in United States, France and 5 more
- Volunteers
- 266 people
- Sponsor
- Gilead Sciences
Lung Cancer, Nonsmall Cell
Pulmonary Function After Arterial Sleeve Lobectomy
Lung cancer is the leading cause of cancer death worldwide. Despite the evolution of medical and multimodal treatments, surgical treatment remains the curative management in the localized cancer.
- Trial name
- NCT04981938
- Testing
- Lobectomy with pulmonary artery reconstruction
- Where
- France
- Volunteers
- 81 people
- Sponsor
- Centre Hospitalier Régional Universitaire Montpellier
Cancer, Immune-related Adverse Event
Extensive CArdioVAscular Characterization and Follow-up of Patients Receiving Immune Checkpoint Inhibitors
The goal of this prospective, multicentre study is to investigate short- and long-term cardiovascular effects in cancer patients treated with immune checkpoint inhibitors (ICIs).
- Conditions
- Cancer, Immune-related Adverse Event, Cardiac Abnormalities, Variable, Immune Checkpoint Inhibitor-Related Myocarditis
- Trial name
- CAVACI (NCT05699915)
- Testing
- Cardiology consultation, Chest Computed Tomography (CT) without contrast, Non-invasive endothelial function tests
- Where
- 4 sites in Belgium
- Volunteers
- 105 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Diabetes Mellitus Risk
Hyperglycaemia In Childhood Hematologic Malignancies
BACKGROUND/AIM: Secondary forms of diabetes are often understudied and underdiagnosed in children and adolescents with cancer. The objectives of this cohort study were to study the incidence and risk factors for hyperglycaemia in…
- Trial name
- DIAB-ONCO (NCT05525364)
- Where
- Belgium
- Volunteers
- 303 people
- Sponsor
- Université Catholique de Louvain
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