Clinical trials: Oncologic Disorders, open to volunteers
Thyroid Cancer
GETNE Registration of Thyroid Cancer
An epidemiological, observational, multicenter, cross-sectional, retrospective study on patients ≥ 18 years visited in the oncology services of the participating centers with diagnosis of primary thyroid cancer.
- Trial name
- NCT03765333
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Grupo Espanol de Tumores Neuroendocrinos
Acute Lymphobkastic Leukemia, Medication Adherence
The AYA Oncology Self-care Movement
This trial will test the impact of a social media intervention for improving oral chemotherapy adherence among adolescents and young adults (AYAs) with acute lymphoblastic leukemia.
- Trial name
- #AYAOSM (NCT07724652)
- Testing
- Educational Website, #AYAOSM
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Northwestern University
Cancer, NGS
Performance Indicators and Impact on the Care Pathway of Sequencing on the SeqOIA and AURAGEN (Seqogen) Platforms for Oncology Patients
As part of the French Genomic Medicine Plan 2025 (FGM), the SeqOIA and AURAGEN platforms were selected to perform high-throughput genomic sequencing.
- Conditions
- Cancer, NGS, Tumor, RARE DISEASE
- Trial name
- SONCO (NCT07147465)
- Where
- 3 sites in France
- Volunteers
- 3,149 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lung Cancer, Lung Cancer Stage I
Feasibility Study to Treat Lung Cancer With the Permanently Implantable LDR CivaSheet®
This is a feasibility study to determine the usefulness of a brachytherapy device that utilizes active components (palladium-103) of standard devices in a novel configuration, which may benefit lung cancer patients by reducing…
- Conditions
- Lung Cancer, Lung Cancer Stage I, Lung Cancer Stage II
- Trial name
- NCT03290534
- Testing
- CivaSheet
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- CivaTech Oncology
Cervical Intraepithelial Neoplasia, Cervical Neoplasms
Gene Therapy Follow up Protocol for Subjects Previously Enrolled in NCI Center for Immuno-Oncology Studies
Background: Gene therapy is closely followed by the U.S. Food and Drug Administration (FDA). The FDA requires researchers to conduct long-term follow-up of people who have had the treatment.
- Conditions
- Cervical Intraepithelial Neoplasia, Cervical Neoplasms, Oropharyngeal Neoplasms, Squamous Intraepithelial Lesions of the Cervix
- Trial name
- NCT04266093
- Testing
- GeneTherapy
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- National Cancer Institute (NCI)
Blood Cancer, Multiple Myeloma (MM)
Development of an Intervention Integrating Procedures Combining Hypnosis and Virtual Reality in the Support of Patients with Hematological Cancer
Research into cancer patients has shown that quality of life is significantly altered by the disease and its associated treatments and is also reported to be a predictor of significant emotional distress.
- Conditions
- Blood Cancer, Multiple Myeloma (MM), Lymphoma
- Trial name
- NCT06817759
- Testing
- Virtual Reality Hypnosis, VRH : Beach, VRH : Forest
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Gynecological Oncology, Gynecology
Yoga in Women With Surgical Menopause After Gynecological Cancer
This randomized controlled trial investigates the effects of yoga on quality of life, sleep quality, and spiritual well-being in women who have entered surgical menopause after gynecological cancer surgery.
- Conditions
- Gynecological Oncology, Gynecology, Oncology, Surgical Menopause
- Trial name
- NCT07141953
- Testing
- Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Dokuz Eylul University
Lung Cancer, Pulmonary Neoplasm
Precision Lung Cancer Survivorship Care Intervention
The overarching goal of the Kentucky LEADS Collaborative Lung Cancer Survivorship Care program is to reduce the burden of lung cancer by offering an innovative survivorship care approach that improves lung cancer quality of life…
- Conditions
- Lung Cancer, Pulmonary Neoplasm, Neoplasms, Lung, Neoplasms, Pulmonary
- Trial name
- KYLEADSII (NCT05857995)
- Testing
- Kentucky LEADS Collaborative Lung Cancer Survivorship Care Program, Enhanced Usual Care
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Jerod L Stapleton, PhD
Neutropenic Fever
Antibiotic Stewardship in Suspected Neutropenic Fever (ASTERIC Trial)
Executive Summary Background: Neutropenic Fever (NF), or febrile neutropenia, occurs in patients with early stage and metastatic solid tumours, non-leukaemic haematological cancers and acute leukaemia.
- Trial name
- NCT06794320
- Testing
- NF Protocol, ASTERIC protocol
- Where
- Hong Kong
- Volunteers
- 648 people
- Sponsor
- The University of Hong Kong
Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma
Mobile Health Intervention to Support Oral Chemotherapy Adherence in Adolescents and Young Adults With Leukemia
This is a small-scale micro-randomized clinical trial of a new mobile just-in-time adaptive intervention (JITAI) designed to promote oral chemotherapy adherence in adolescents and young adults (AYA) with acute lymphoblastic…
- Trial name
- NCT03932903
- Testing
- ADAPTS (ADherence Assessments and Personalized Timely Support).
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Northwestern University
Colorectal (Colon or Rectal) Cancer, STOMACH NEOPLASM
Perioperative Biomarkers in Colorectal and Gastric Cancer Surgery
This study aims to evaluate whether monitoring perioperative inflammatory and metabolic biomarkers can help identify postoperative complications early in adult patients undergoing colorectal or gastric cancer surgery.
- Trial name
- PERIO-BIO (NCT07881133)
- Testing
- Perioperative Biomarker-Guided Monitoring
- Where
- Romania
- Volunteers
- 320 people
- Sponsor
- Bucharest Emergency Hospital
Brain Metastases
University of Kentucky Markey Cancer Center Neuro-Oncology Multi-Disciplinary Tumor Board Protocol for the Treatment of Advanced Brain Metastases
This study evaluates whether review by the University of Kentucky Markey Cancer Center Neuro-Oncology Multidisciplinary Tumor Board improves clinical outcomes for adults with advanced brain metastases.
- Trial name
- NCT07786311
- Testing
- Neuro-Oncology Multi-Disciplinary Tumor Board Review
- Volunteers
- 125 people
- Sponsor
- John L. Villano, MD, PhD
Lung Cancer
Empathic Communication Skills (ECS) Training
Research indicates that perceived stigma within medical encounters is prevalent and problematic for lung cancer patients' well-being and quality of cancer care.
- Trial name
- NCT05456841
- Testing
- Empathic Communication Skills (ECS) training, Standard of Care participant interaction
- Where
- 12 sites in United States
- Volunteers
- 1,232 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Pregnancy Related, Immune-mediated Diseases
Impact of In Utero Exposure to Immunomodulatory Drugs on Neonatal Immune System Development
What is this project about? This project aims to better understand how the immune system develops in babies whose mothers received immunomodulatory treatments during pregnancy.
- Trial name
- NEWbornIMMPACT (NCT07033663)
- Testing
- Monoclonal antibody
- Where
- 3 sites in Spain
- Volunteers
- 90 people
- Sponsor
- Fundació Sant Joan de Déu
Head &Amp;Amp; Neck Squamous Cell Carcinoma
The FORCE Trial Pilot: Fish Oil-enriched Nutrition for Radiotherapy in Cancer of the hEad and Neck
en-label, proof-of-concept study designed to evaluate the feasibility, safety, and acceptability of a prophylactic fish oil-enriched nutritional supplement (Fresubin Supportan) in patients with head and neck cancer (HNC)…
- Trial name
- FORCE (NCT07180576)
- Testing
- Nutrition counseling, Fresubin Supportan
- Volunteers
- 15 people
- Sponsor
- Anna Arthur, PhD
Breast Cancer, Prostate Cancer
Precise Oncology Interventions in Nutrition and Training (OnPoint)
The purpose of this study is to see if survivors of breast, prostate, colorectal or lymphoma cancer who receive a personal referral to a targeted nutrition and exercise program will be able to eat a healthier diet and be more…
- Conditions
- Breast Cancer, Prostate Cancer, Colorectal Cancer, Lymphoma
- Trial name
- OnPoint (NCT06534918)
- Testing
- Fitbit, Nutrition Course: Group Sessions, Physical Activity Program: Group Sessions
- Where
- United States
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- University of Miami
Acupuncture, Breast Cancer
Stress Reduction Through Acupuncture
This randomized controlled trial evaluates whether eight weeks of weekly acupuncture can reduce psychological distress in breast cancer patients who have recently completed primary therapy compared to standard-of-care wait-list…
- Conditions
- Acupuncture, Breast Cancer, Survivorship
- Trial name
- STREAK (NCT07132034)
- Testing
- Acupuncture, Standard supportive care
- Where
- 3 sites in Switzerland
- Volunteers
- 112 people
- Sponsor
- Isabell Xiang Ge
Gynecologic Cancer, Frailty
Measuring Ultrasound Guided Skeletal Muscle Mass of Lower Extremity as a Predictor of Post-Operative Length of Stay in Exploratory Gynae-oncology Surgeries
Increased incidence of Gynae-oncological cancer is observed specifically in women above 50 years of age. Sarcopenia (a progressive and generalized loss of skeletal muscle mass, quality, and strength) is considered a reliable…
- Conditions
- Gynecologic Cancer, Frailty, Sarcopenia
- Trial name
- MUSLES (NCT06816836)
- Testing
- Bed Side ultrasound guided muscle mass estimation of lower extremity
- Where
- India
- Volunteers
- 320 people
- Sponsor
- Tata Medical Center
Advanced Malignant Tumors
A Study of BMS-986488 as Monotherapy and Combination Therapy in Participants With Advanced Malignant Tumors
This purpose of this study is to determine if experimental treatment with BMS-986488, alone, or in combinations is safe, tolerable, and has anti-cancer activity in patients with advanced malignant tumors.
- Trial name
- NCT06764771
- Testing
- BMS-986488, Adagrasib, Cetuximab
- Where
- 8 sites in United States, Australia and 1 more
- Volunteers
- 437 people
- Sponsor
- Bristol-Myers Squibb
Colorectal Cancer, Sarcopenia
Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer
This study will examine the association between low muscle mass (myopenia) at diagnosis and chemotherapy toxicity in older adults with newly diagnosed advanced colorectal cancer.
- Trial name
- M&M (NCT03998202)
- Where
- 147 sites in United States
- Volunteers
- 300 people
- Sponsor
- Wake Forest University Health Sciences