Clinical trials: Oncologic Patients
Depression, Anxiety, Cancer of the Head and Neck
Mindfulness-based Stress Reduction Effects on Depression, Anxiety and Internalized Stigma Compared With Treatment-As-Usual Among Head and Neck Cancer Patients
Head and neck cancer patients are vulnerable to various psychological complications due to the effects of both cancer itself and cancer treatment on patients' appearance and physical well-being.
- Conditions
- Depression, Anxiety, Cancer of the Head and Neck, Psycho-Oncology
- Trial name
- NCT06991309
- Testing
- MBSR
- Where
- Malaysia
- Volunteers
- 110 people
- Sponsor
- Universiti Sains Malaysia
Colo-rectal Cancer
NURSE-led Geriatric Assessment in Older Colorectal Cancer Patients
Older colorectal cancer patients frequently present with frailty, comorbidity, and other age-related vulnerabilities that may affect treatment tolerance and outcomes.
- Trial name
- NURSE-GA (NCT07872787)
- Testing
- Nurse-led Geriatric Assessment
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Helse Stavanger HF
Cancer Metastatic, Cancer
Telerehabilitation in Oncology Patients
The aim is to analyze the feasibility and effect of an online Therapeutic Exercise and Education programme (TEEP) in cancer patient and survivors
- Conditions
- Cancer Metastatic, Cancer, Survivorship
- Trial name
- NCT04547634
- Testing
- Therapeutic Exercise and Education
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- University of Malaga
Nasopharyngeal Carcinoma
A Study of Anti-PD-1 AK105 in Patients With Metastatic Nasopharyngeal Carcinoma
This is a multicenter, single-arm open-label, phase II study to evaluate the anti-tumor activity, safety, PK and immunogenicity of AK105 (Anti-PD1 antibody) in patients with metastatic nasopharyngeal carcinoma who have progressed…
- Trial name
- NCT03866967
- Testing
- AK105
- Where
- 2 sites in China
- Volunteers
- 130 people
- Sponsor
- Akeso
Squamous Cell Carcinoma of the Head and Neck
Cabazitaxel - PF Induction Chemotherapy
The primary objective of this study is to determine the first-cycle maximum tolerated dose (MTD) and recommended Phase II (RP2D) dose of Cabazitaxel when combined with Cisplatin and Follow-Up induction chemotherapy in patients…
- Trial name
- NCT01379339
- Testing
- Cabazitaxel 10mg/m2, Cabazitaxel 12.5mg/m2, Cabazitaxel 15mg/m2
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Krzysztof Misiukiewicz
Cardio-Oncology, Rehabilitation
Cardio-Oncology Rehabilitation Care Process
The objective of this observational study is to assess the outcomes of a hospital-based Cardio-Oncology Rehabilitation (CORe) program focused on exercise in cancer patients undergoing cardiotoxic treatment.
- Conditions
- Cardio-Oncology, Rehabilitation, Cardiovascular Diseases, Exercise
- Trial name
- ReCO (NCT06302634)
- Testing
- Exercise-based cardio-oncology rehabilitation
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Hospital Clinico Universitario de Santiago
Hematopoietic Stem Cell Transplantation, Cardiotoxicity
Effect of Angiotensin Converting Enzyme and Sacubitril Valsartan in Patients After Bone Marrow Transplantation
The purpose of the present study is to investigate the effect of ACE inhibitors and the sacubitril-valsartan complex in bone marrow transplant patients by assessing cardiovascular and endothelial parameters in order to search for…
- Trial name
- NCT04092309
- Testing
- ACE inhibitor, Sacubitril-Valsartan
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- University of Athens
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Survey Assessment of Patient and Provider Impressions of Telemedicine in Radiation Oncology
To understand more about the opinions of patients and health providers on the use of telemedicine in radiation oncology.
- Trial name
- NCT05496972
- Testing
- Survey Administration
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- M.D. Anderson Cancer Center
Neoplasms
Perceptions of Cell and Gene Therapies (CGT) for the Treatment of Cancer
Gene and cell therapies have a real value potential (example: potential long-term effect, curative potential, and single administration) but also drawbacks (example: treatment perceived as complex and risky generating fear and…
- Trial name
- NCT03336567
- Testing
- Telephonic interview
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- GlaxoSmithKline
Breast Cancer
Impact of Osteopathy on Pain After Breast Cancer Surgery
Breast cancer can be painful following surgery or can develop later and remain persistent. Pain occurrence is frequent with 50% of women developing sequelae pain of varying intensity with an impact on the quality of life.
- Trial name
- IPOD (NCT02621437)
- Testing
- Osteopathy sessions, phone questionnaires
- Where
- France
- Volunteers
- 161 people
- Sponsor
- Hospices Civils de Lyon
Stomatitis
Safety and Efficacy of CG53135-05 in the Prevention of Oral Mucositis in Patients Receiving Bone Marrow Transplant
CG53135-05, a recombinant human fibroblast growth factor-20 (rhFGF-20) protein, is under investigation for the prevention of oral mucositis.
- Trial name
- NCT00104065
- Testing
- CG53135-05, velafermin
- Where
- 9 sites in United States
- Sponsor
- CuraGen Corporation
Oral Mucositis Due to Chemotherapy, Hematolymphoid Malignancies
Phase II Single Arm Open Label Study Evaluating the Feasibility and Safety of Photobiomodulation as an Adjunct to Standard Supportive Care for Chemotherapy Induced Oral Mucositis in Pediatric Patients With Hematolymphoid Malignancies
Chemotherapy induced oral mucositis is a common and debilitating complication in pediatric patients receiving chemotherapy for hematolymphoid malignancies.
- Trial name
- BEAM (NCT07605234)
- Testing
- Photobiomodulation Therapy
- Volunteers
- 46 people
- Sponsor
- Tata Memorial Hospital
Gastroesophageal Cancer, Immune Checkpoint Inhibition
REACTION (Radiation Enhanced Assessment of Combination Therapies in Immuno-ONcology) - Nivolumab or Nivolumab in Combination With Other Immuno-oncology (IO) Agents After Targeted Systemic Radiation in Patients With Advanced Esophagogastric Cancer
This is a Phase 1B study assessing the safety of immune checkpoint inhibition after SBRT in patients with recurrent or metastatic gastroesophageal cancer (limited metastatic disease).
- Trial name
- REACTION (NCT03610711)
- Testing
- Nivolumab, Relatlimab
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Female Reproductive Cancer
Feeding Schedules After Surgery in Patients With Gynecologic Cancer
RATIONALE: Abdominal pain and nausea and vomiting may be lessened by waiting after surgery before eating foods by mouth. It is not yet known which feeding schedule is more effective in patients undergoing surgery.
- Trial name
- NCT00742677
- Testing
- nutritional support
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- European Institute of Oncology
Financial Toxicity, Cancer
Implementing Stepped Financial and Legal Navigation to Mitigate Financial Toxicity in Adolescent and Young Adult Cancer Patients Oncology Financial and Legal Navigation (OFLN)
The overall objective of this study is to test the effectiveness and implementability of stepped Oncology Financial and Legal Navigation (OFLN) in a noninferiority randomized controlled trial (RCT) using a hybrid type 1…
- Conditions
- Financial Toxicity, Cancer, Adolescent, Young Adult Cancer Survivors
- Trial name
- OFLN (NCT07849699)
- Testing
- Oncology Financial and Legal Navigation (OFLN) Stepped: Low Intensity, Oncology Financial and Legal Navigation (OFLN) Standard, Oncology Financial and Legal Navigation (OFLN) Stepped: High-Intensity
- Where
- United States
- Volunteers
- 294 people
- Sponsor
- University of Louisville
Tumor, Solid
BDB001-201: A Clinical Study of BDB001 in Patients With PD-(L)1 Refractory Solid Tumors
BDB001-201 is a multi-center, open-label, Phase II clinical trial to evaluate the efficacy and safety of BDB001 in the treatment of subjects with advanced solid tumors that have progressed on anti-PD-1 or anti-PD-L1 mAb treatment.
- Trial name
- NCT04819373
- Testing
- BDB001
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Eikon Therapeutics
Supportive Care
The Efficacy of Implementing Nurse-performed Ultrasound-guided Peripheral Intravenous Access in Oncology Patients
The purpose of this study is to investigate the clinical efficacy of nurse-performed ultrasound-guided intravenous access in oncology patients on the oncological outpatient unit in the National Hospital of the Faroe Islands.
- Trial name
- NCT06578494
- Testing
- Ultrasound
- Volunteers
- 40 people
- Sponsor
- Faroese Hospital System
Caregiver Burden, Care Giving Burden
Online Educational Tool for Caregivers of Pediatric Oncology Patients
The goal of this study is to assess the feasibility of using a game-based tool for caregivers of pediatric oncology patients to increase caregiver knowledge about supportive care for oncology patients while simultaneously…
- Conditions
- Caregiver Burden, Care Giving Burden, Pediatric Cancer
- Trial name
- NCT05616572
- Testing
- OncoWhiz
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Washington University School of Medicine
Exhaustion, Geriatric Disorder
Nursing Follow up in Geriatric Oncology : Tracking Time of Caregiver Exhaustion Risk
In geriatric oncology, caregivers are submitted to a risk of exhaustion. To investigate the clinical risk factor of exhaustion, the researchers propose to conduct a prospective observational study during 6 months phone follow up…
- Trial name
- TANGO (NCT02551965)
- Testing
- Phone nursing follow-up
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Neoplasms
Interindividual Genetic Variability as a Determinant of Chemotherapy Toxicity and Response in Pediatric Bone Marrow Transplantation Patients
The purpose of this study is to develop tests that will allow us to determine who will react differently to the drugs used to treat cancer.
- Trial name
- NCT00578630
- Testing
- buccal swabs and obtaining peripheral blood
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
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