Clinical trials: Oncologic Patients
Neuroblastoma
Impact of Image-defined Risk Factors on the Outcome of Patients With Neuroblastoma: A Retrospective Study
The aim of this study is to evaluate Image-defined Risk Factors (IDRF) in patients with neuroblastoma, at the time of their initial presentation, as a prognostic factor for prediction of subsequent outcome \& complications…
- Trial name
- NCT02558244
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Needs and Demands of Oncology Patients, Breast Cancer Patients.
The Needs of Cancer Survivors
A questionaire for cancer patients without an active treatment in order to evaluate their needs and/or demands.
- Conditions
- Needs and Demands of Oncology Patients, Breast Cancer Patients., Colon Cancer Patients.
- Trial name
- NCT01686971
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Rambam Health Care Campus
Chemotherapy-induced Nausea and Vomiting, Pediatric Cancer
Effect of Guided Imagery on Chemotherapy-related Nausea and Vomiting
The goal of this randomized controlled study is to assess the effect of guided imagery on chemotherapy-related nausea and vomiting in pediatric oncology patients.
- Trial name
- NCT06120764
- Testing
- guided imagery
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Baskent University
Cancer
Phase 1/2a Study of SQ3370 in Patients With Advanced Solid Tumors
The purpose of this study is to evaluate the safety, tolerability, and preliminary activity of SQ3370 in patients with advanced solid tumors.
- Trial name
- NCT04106492
- Testing
- SQ3370
- Where
- 10 sites in United States, Australia
- Volunteers
- 53 people
- Sponsor
- Shasqi, Inc.
Cancer
A Study of ApricityRx™ for Management of IR-AEs in Patients on Immuno-Oncology Therapy
Study of ApricityRx™ for Management of IR-AEs for patients on I-O therapy. Patients currently receiving immunotherapy will be asked to consent to participate in ApricityRx software platform mobile telephone application to report…
- Trial name
- NCT04571398
- Testing
- ApricityRx mobile application
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Apricity Health, Inc
Breast Cancer
PTK787 + Trastuzumab for HER2 Overexpressing Metastatic Breast Cancer
HER2 gene amplification increases VEGF production in breast cancers; combined inhibition of HER2 and VEGF enhances response in xenograft models.
- Trial name
- NCT00216047
- Testing
- PTK787, Trastuzumab
- Where
- 8 sites in United States
- Volunteers
- 7 people
- Sponsor
- Hoosier Cancer Research Network
Other Cancer, Gastrointestinal Cancer
Symptom Management Implementation of Patient Reported Outcomes in Oncology
Deficits in the management of common symptoms cause substantial morbidity for cancer patients.Because the health care delivery system is structured to be reactive and not proactive, there are missed opportunities to optimize…
- Conditions
- Other Cancer, Gastrointestinal Cancer, Thoracic Cancer, Gynecologic Cancer
- Trial name
- SIMPRO (NCT03850912)
- Testing
- Stakeholder Survey (Control Period), Stakeholder Survey (Intervention Period), Qualitative Interview
- Where
- 6 sites in United States
- Volunteers
- 42,808 people
- Sponsor
- Dana-Farber Cancer Institute
Neoplasm
Role of the Pharmacist in Detection of Drug Interactions Before Antitumor Treatment Initiation
The purpose of this observational study is to evaluate the benefits of a pharmacist integration in an oncology ambulatory center, to prevent drug related problems (in particular drug drug interactions) at antitumor treatment…
- Trial name
- CHOPIN (NCT04142567)
- Where
- France
- Volunteers
- 440 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Non Small Cell Lung Cancer, Liquid Biopsy
ProSpecTive sAmpling in dRiver muTation Pulmonary Oncology Patients on Tyrosine Kinase Inhibitors (START-TKI)
The study is perfomed with adult patients with non-small cell lung cancer treated with tyrosine kinase inhibitor. The objective is to collect repeated samples of blood from patients (starting) on a tyrosine kinase inhibitor, for…
- Conditions
- Non Small Cell Lung Cancer, Liquid Biopsy, Tyrosine Kinase Inhibitor
- Trial name
- START-TKI (NCT05221372)
- Where
- Netherlands
- Volunteers
- 1,300 people
- Sponsor
- Erasmus Medical Center
Oral Mucositis, Chemotherapeutic Toxicity
Comparison of Prophylactic Photobiomodulation Protocols in Chemoinduced Oral Mucositis in Oncology Patients
Childhood cancers represent less than 1% of the malignant diseases diagnosed worldwide. Treatment modalities for childhood malignancies will differ depending on the diagnosis.
- Conditions
- Oral Mucositis, Chemotherapeutic Toxicity, Childhood Cancer
- Trial name
- NCT05811195
- Testing
- Diode Semiconductor, Duo, Gemini laser
- Where
- Brazil
- Volunteers
- 34 people
- Sponsor
- Federal University of Rio Grande do Sul
Metastatic Cancer, Palliatives Treatments
Towards an Early Integration of Palliative Care in Oncology
The primary objective of the study is to describe the nature and to estimate the prevalence the health needs of patients with metastatic cancer and their main caregivers, between the period from diagnosis to death.
- Trial name
- BESACE (NCT05339945)
- Where
- France
- Volunteers
- 361 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Head and Neck Cancer
Goal Directed Fluid Therapy in Free Flap Reconstructive Surgery
Wide excision of head and neck cancer with microsurgical free flap's reconstruction (FFR) results to a high cancer cure rate and a good functional recovery.
- Trial name
- NCT01129037
- Testing
- Goal directed fluid management based on continuous monitoring of stroke volume
- Where
- Canada
- Volunteers
- 78 people
- Sponsor
- University Health Network, Toronto
Wound Complications, Wound Infection
A Study to Evaluate a Quality Improvement Intervention to Reduce Wound Separation Rates in Obese Gynecologic Oncology Service Patients Undergoing Abdominal Surgery
Approximately 500,000 surgical site infections occur annually in the US. These lead to worse patient quality of life, more outpatient and emergency room visits, readmissions and home services, with an estimated increase in costs…
- Conditions
- Wound Complications, Wound Infection, Wound Separation
- Trial name
- NCT02071251
- Testing
- Prospective wound complication protocol
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Washington University School of Medicine
Chronic Myeloid Leukemia, Chronic Lymphocytic Leukemia
Pharmacists Coordinated Care Oncology Model (PCOM) for Patients Taking Oral Anti-cancer Medications
The objective of this study is to improve medication, symptom, and disease management of patients with hematological malignancies and multiple chronic conditions (2 or more conditions in addition to cancer) through care…
- Conditions
- Chronic Myeloid Leukemia, Chronic Lymphocytic Leukemia, Multiple Chronic Conditions
- Trial name
- NCT04595851
- Testing
- Patient Reported Outcome Measure (PROM), Comprehensive Medication Review (CMR), Communications between oncology and primary care pharmacists
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Michigan Rogel Cancer Center
Oral Mucositis
Investigation of the Effect of Oral Care With Coconut Oil on the Degree of Oral Mucositis in Pediatric Oncology Patients
Oral mucositis is characterized by ulcerative and inflammatory changes in the oral mucosa and is frequently seen in pediatric oncology patients receiving chemotherapy.
- Trial name
- NCT05849571
- Testing
- coconut oil
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Büşra Ekinci
Pediatric Oncology
Fit to Fight Childhood Cancer
The aim of the study is to investigate the influence of exercise on physical performance and psychosocial aspects in children and adolescents with cancer during and after treatment.
- Trial name
- Kolibri (NCT05867186)
- Testing
- Exercise training
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Johannes Gutenberg University Mainz
Medical Intensive Care Unit (MICU) Patients, Oncology Unit Patients
Promoting Respect and Ongoing Safety Through Patient-centeredness, Engagement, Communication and Technology
The purpose of this project is to refine, implement, and evaluate a multi-component intervention that achieves sustainable and meaningful impact on healthcare quality, safety, and costs while ensuring dignity and respect for…
- Trial name
- PROSPECT (NCT02258594)
- Testing
- Web-Based Patient Centered Toolkit (PCTK), The Patient-SatisfActive® Model
- Where
- United States
- Volunteers
- 4,368 people
- Sponsor
- Brigham and Women's Hospital
Neoplasms
Drug-Drug Interaction Study of Rucaparib, Rosuvastatin and Oral Contraceptives
This study will investigate the drug-drug interactions (DDIs) between rucaparib and oral rosuvastatin (Arm A), and between rucaparib and oral ethinylestradiol and levonorgestrel (Arm B), with rucaparib as a perpetrator.
- Trial name
- NCT03954366
- Testing
- Rucaparib, Rosuvastatin, Oral Contraceptives
- Where
- 7 sites in Hungary, Poland and 1 more
- Volunteers
- 36 people
- Sponsor
- pharmaand GmbH
Colorectal Cancer
Advocacy, Partnership, Outreach, and Yielding Optimized Care for Oncology Patients
This study is a pilot feasibility randomized trial involving newly diagnosed colorectal cancer (CRC) patients who identify as Latinx.
- Trial name
- NCT07403981
- Testing
- CHW/P Navigator Support, Social Services Resource List
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Stanford University
Neoplasms
A Pharmacokinetic Study of Valacyclovir in Pediatric Oncology Patients
The purpose of this research is to study the pharmacology (how the body handles this drug) of valacyclovir in children receiving treatment for cancer. This study will last approximately 7 days.
- Trial name
- NCT00042328
- Testing
- Valacyclovir
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Baylor College of Medicine
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