Clinical trials: Oncologic Patients
Cardiotoxicity, Lung Cancer Stage III
Cardiotoxicity in Locally Advanced Lung Cancer Patients Treated With Chemoradiation Therapy
This observational cohort will evaluate the cardiovascular effects of chemoradiation used to treat locally advanced, non-small cell lung cancer.
- Conditions
- Cardiotoxicity, Lung Cancer Stage III, Lung Cancer Stage II, Radiation Toxicity
- Trial name
- CLARITY (NCT04305613)
- Testing
- Chemoradiation
- Where
- 8 sites in United States
- Volunteers
- 221 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Atrial Fibrillation (AF), Chronic Lymphocytic Leukemia
Atrial Fibrillation Among Patients With Hematologic Malignancies on Tyrosine Kinase Inhibitor Therapy
This study looks at how often atrial fibrillation (AF), an irregular heart rhythm, occurs in people with certain blood cancers who are starting a type of cancer medicine called a Bruton's tyrosine kinase inhibitor (BTKI).
- Conditions
- Atrial Fibrillation (AF), Chronic Lymphocytic Leukemia, Waldenstrom Macroglobulinemia, Mantle Cell Lymphoma
- Trial name
- NCT07711327
- Where
- 3 sites in United States
- Volunteers
- 500 people
- Sponsor
- Tina Baykaner
Metastatic Urothelial Carcinoma
Urine Omics Predicting IO Therapy Responses in mUC Patients
The study aims to identify urinary metabolite and protein markers that can predict anti-tumor efficacy and adverse events in subjects receiving IO-based therapies for metastatic urothelial carcinoma.
- Trial name
- NCT04641936
- Testing
- No intervention required
- Where
- Taiwan
- Volunteers
- 600 people
- Sponsor
- National Taiwan University Hospital
Solid Tumors
AS703569 Phase I in Patients With Solid Tumours
This is a Phase I trial. Some specific protocol information is proprietary and is not publicly available at this time. Full information will be provided to trial participants.
- Trial name
- NCT00391521
- Testing
- AS703569
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- EMD Serono
BRCA1/2 Mutation, Breast-conserving Surgery
Long-term Oncologic Outcome of Breast-conserving Surgery in Breast Cancer Patients With BRCA1/2 Mutations
The investigators matched BCS and mastectomy group using propensity scores and analyzed the recurrence and survival among the evenly matched patients in breast cancer patients with BRCA 1/2 mutations.
- Trial name
- NCT06429644
- Testing
- Breast-conserving surgery
- Where
- South Korea
- Volunteers
- 4,010 people
- Sponsor
- Hanyang University Seoul Hospital
Oncology Patients
Utilization of Virtual Reality to Increase Comfort and Reduce Procedural Distress During Port Insertion Into the Body
This randomised controlled study evaluates whether virtual reality (VR) can support patient comfort and help reduce anxiety and stress during subcutaneous venous port implantation in adult oncology patients.
- Trial name
- NCT06927804
- Testing
- Virtual reality intervention, Standard Care (in control arm)
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- University Hospital Ostrava
Ovarian Cancer
Study of the mTOR Inhibitor Temsirolimus (CCI-779) to Treat Ovarian Cancer With CA125 Only Relapse
The primary objective of this study is to determine the efficacy of Temsirolimus in patients with ovarian cancer with CA125 only relapse after first-line platinum-based chemotherapy.
- Trial name
- NCT00926107
- Testing
- Temsirolimus
- Where
- 12 sites in Greece
- Volunteers
- 9 people
- Sponsor
- Hellenic Cooperative Oncology Group
Children With Relapsed Solid Tumor, Lymphoma or Leukemia
Vorinostat in Children
The aim of this study is to define a dose recommendation of vorinostat in pediatric oncology, to determine pharmacokinetics of vorinostat in children, determine response rates, safety and feasibility.
- Trial name
- NCT01422499
- Testing
- zolinza/vorinostat
- Where
- 10 sites in Germany
- Volunteers
- 50 people
- Sponsor
- National Center for Tumor Diseases, Heidelberg
Breast Cancer
Oncologic Outcomes and Toxicities of Salvage Treatment in Patients With Locoregionally Recurrent Breast Cancer
The purpose of this study is to evaluate clinical outcomes and adverse events of salvage treatment for locoregional recurrence of breast cancer.
- Trial name
- SALT-LRR (NCT05933733)
- Testing
- Salvage treatment (surgery and/or radiation therapy)
- Where
- South Korea
- Volunteers
- 190 people
- Sponsor
- Samsung Medical Center
Cancer Patients
Effectiveness of Video Assisted Self Management Program on Chemotherapy Related Side Effects .
A study to assess the effectiveness of video assisted Self Management Program on chemotherapy side effects in terms of Knowledge, Self Efficacy and Severity of side effects among the Cancer patient receiving chemotherapy at…
- Trial name
- NCT05368116
- Testing
- Video Assisted Self Management Program, Standard of care
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Pain, Anxiety
Effect of Virtual Reality on Pain, Anxiety, and Vital Signs of the Patients Undergoing Port Catheter Implantation
This study aimed to determine the effect of virtual reality on pain, anxiety, and vital signs of oncology patients undergoing port catheter implantation.
- Conditions
- Pain, Anxiety, Blood Pressure, Body Temperature Changes
- Trial name
- NCT05140707
- Testing
- Virtual Reality Distraction
- Where
- Turkey (Türkiye)
- Volunteers
- 139 people
- Sponsor
- Inonu University
Brain Cancer
Refining and Testing the Electronic Social Network Assessment Program (eSNAP)
The purpose of the study is to learn more about neuro-oncology caregivers' quality of life and how friends and families help neuro-oncology cancer caregivers at different times during treatment.
- Trial name
- NCT03026699
- Testing
- eSNAP, Questionnaires
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Anxiety, Quality of Life
Using Meditation for Oncology Anxiety
The current study is a prospective, interventional, randomized, treatment-controlled study, evaluating the use of Meditation with a Mantra (MM) to decrease anxiety levels and improve Quality of Life (QOL) in prostate cancer…
- Conditions
- Anxiety, Quality of Life, Prostate Cancer, Prostate Cancer Recurrent
- Trial name
- NCT04312191
- Testing
- Mantra Meditation
- Sponsor
- Mellar Davis MD
Oncology, Cardiac Disease
Ask Questions About Clinical Trials
The overall goal of this study is to assess the implementation of the Ask Questions about Clinical Trials (ASQ-CT) brochure, a patient-focused communication tool previously demonstrated to improve patient-provider communication…
- Conditions
- Oncology, Cardiac Disease, Neurologic Disorder
- Trial name
- ASQ-CT (NCT07343297)
- Testing
- Ask Questions about Clinical Trials brochure
- Where
- 8 sites in United States
- Volunteers
- 293 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Infection
Vancomycin Serum Concentrations in Pediatric Oncology Patients Under Intensive Care
Observational protocol to analyse routine vancomycin serum levels of patients under intensive care and to obtain percentage of patients that achieve therapeutic values.
- Trial name
- NCT01304459
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Grupo de Apoio ao Adolescente e a Crianca com Cancer
Gynaecological Cancer
Palliation in Gynae-oncology: Patients Expectations and Assessment of Care (PEACE)
The overall aim is to assess the feasibility and acceptability of collecting data on the patients and carers perception of care as well as to prospectively monitor end of life care.
- Trial name
- PEACE (NCT05142150)
- Testing
- Questionaire
- Where
- Norway
- Volunteers
- 73 people
- Sponsor
- Nordic Society of Gynaecological Oncology - Clinical Trials Unit
Acquired Brain Injury
SAFIR© : An Early Intervention for Supporting Families of Patients With Acquired Brain Injuries
The aim of the study is to evaluate the feasibility of a newly developed intervention to improve family support for patient with acquired brain injury (ABI) in early phase of hospitalization (SAFIR): the main components are the…
- Trial name
- SAFIR© (NCT04138524)
- Testing
- SAFIR©
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Cancer, Psycho-Oncology
What Impact Does an Initial Psycho-oncological Contact Have on People With Cancer?
When diagnosed with cancer, patients or their relatives may, if they wish, on the recommendation of the treatment team and/or in cases of high stress, seek psycho-oncological support.
- Trial name
- PICS (NCT07544446)
- Testing
- initial psycho-oncological contact, Standard
- Where
- 5 sites in Switzerland
- Volunteers
- 148 people
- Sponsor
- Lindenhofgruppe AG
Advance Directives, Oncology
ACCEPTABILITY AND WRITING FREQUENCY OF ADVANCED DIRECTIVES IN ONCO-DERMATOLOGY PATIENTS
The law about advance directives is evolving but, in France, few people write it. Te main endpoint of this research is to estimate the proportion of patients who have written their advance directives or considering doing so in…
- Conditions
- Advance Directives, Oncology, Skin Cancer, Melanoma
- Trial name
- PADAONCODERM (NCT03822988)
- Testing
- no intervention, only complete a survey
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Central Hospital, Nancy, France
Gynecologic Cancer, Sexual Dysfunction
Sexual Dysfunction in Gynecologic Oncology Patients
This project will evaluate sexual dysfunction in women who have had surgery for gynecologic cancer. The subjects will complete a set of questionnaires about health, daily living, sexual encounters, and pain before their surgery…
- Trial name
- NCT03801031
- Testing
- Lidocaine Topical
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- David Bender
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