Clinical trials: Oncological Outcomes
Rectal Neoplasms
Selection of Surgical Technique in Rectal Cancer
Currently, there is no prediction scale available to identify patients with rectal neoplasms as technically complex in the middle and lower thirds; that is, those who are at high risk of affected circumferential margins and low…
- Trial name
- TECARE (NCT06442215)
- Testing
- Data collection
- Where
- Spain
- Volunteers
- 333 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Colorectal Cancer
Neutrophil-to-Lymphocite Ratio (NLR) and C-reactive Protein (CRP) as New Markers in Diagnosis and Prediction of Colorectal Cancer
Colorectal cancer (CRC) is the second leading cause of cancer-related death in the Western world. Overall survival (OS) remains poor, with 50% estimated 5-year survival.
- Trial name
- NelyCre (NCT05129046)
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Bladder Cancer
Oncological Outcomes of Different Patterns of Tumor Recurrence at First Evaluation After Bacillus Calmette-Guérin Induction Therapy for Intermediate and High Risk Non Muscle Invasive Bladder Cancer
This retrospective study aimed at assessment of different patterns (morphological and pathological) of tumor recurrence found at first evaluation after BCG induction therapy (3 months cystoscopy) for intermediate and high-risk…
- Trial name
- NCT04319263
- Testing
- induction regimen of intravesical BCG
- Where
- Egypt
- Volunteers
- 1,600 people
- Sponsor
- Mansoura University
Breast Cancer
Single-dose Preoperative Partial Breast Irradiation in Low-risk Breast Cancer Patients
In this ABLATIVE-2 trial, low-risk breast cancer patients will be treated with MRI-guided single dose preoperative partial breast radiotherapy to assess the rate of pathologic complete response after an interval of six to twelve…
- Trial name
- ABLATIVE-2 (NCT05350722)
- Testing
- Single dose ablative radiotherapy
- Where
- 7 sites in Australia, Netherlands
- Volunteers
- 100 people
- Sponsor
- Amsterdam UMC, location VUmc
Prostate Cancer
FOCAL HIGH-INTENSITY FOCUSED ULTRASOUND FOR PRIMARY LOCALIZED PROSTATE CANCER: MIDTERM ONCOLOGICAL OUTCOMES
Single-center evaluation of all patients treated for primary localized prostate cancer with focal HIFU from November 2009 to December 2016.
- Trial name
- Focal HIFU for (NCT04602208)
- Testing
- Retrospectively review of medical data in patients treated by focal HIFU for primary localized prostate cancer
- Where
- France
- Volunteers
- 146 people
- Sponsor
- Hospices Civils de Lyon
Breast Cancer
The OPBC-07/microNAC Study
The aim of this multicenter retrospective cohort study is to determine the safety of omission of axillary lymph node dissection in patients with residual micrometastases after neoadjuvant chemotherapy.
- Trial name
- NCT06529302
- Where
- 84 sites in United States, Argentina and 28 more
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Basel, Switzerland
the Focus of This Study is to Develop an Application for Postoperative Follow-up of Patients With Prostate Cancer
Digital Application Usage for Adherence of Patients Undergoing Robotic Assisted Radical Prostatectomy Following Oncological and Postoperative Functional Outcomes
Prostate cancer (PC) is the most common non-skin tumor in men and the second leading cause of death from cancer in Brazil. It accounts for 13.8% of deaths from cancer in males, similar to what happens with breast cancer in…
- Trial name
- NCT02809495
- Testing
- use of app in smartphone
- Volunteers
- 100 people
- Sponsor
- University of Sao Paulo General Hospital
Prostate Cancer
Oncological and Functional Outcomes After Radical Prostatectomy for Prostate Cancer: Comparing Open With Robot-assisted Surgery
For primary surgical treatment of prostate cancer the investigators compare the classic open surgery (radical retropubic prostatectomy, RRP) versus robot-assisted laparoscopic surgery (RALP).
- Trial name
- NCT01578356
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
D010051, Ovarian Cancer
Validation of ESGO Quality Indicators in Advanced Ovarian Cancer Surgery
This study, organized by the European Society of Gynaecological Oncology (ESGO), evaluates the clinical impact of adherence to ten ESGO-established quality indicators (QIs) in advanced ovarian cancer surgery.
- Conditions
- D010051, Ovarian Cancer, Advanced-stage Ovarian Cancer, FIGO Stages III and IV
- Trial name
- retroESGO ov1 (NCT07567573)
- Testing
- Preoperative Evaluations, Cytoreductive Surgery, Perioperative Management
- Where
- Belgium
- Volunteers
- 11,383 people
- Sponsor
- European Society of Gynaecological Oncology
Colonic Neoplasms Malignant, Cecal Neoplasms
Local Cecal Cancer - Optimization of Surgical Treatment
The purpose of this study is to determine the clinical efficacy, safety, and oncologic outcomes of ileocecal resection (ICR) with D3 lymphadenectomy compared to standard right hemicolectomy(RHC) for cecal cancer.
- Trial name
- LoCCOSTe (NCT06121089)
- Testing
- ileocecal resection with extended D3 lymphadenectomy., Right hemicolectomy with D3 lymphadenectomy.
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Moscow Clinical Scientific Center
Prostate Cancer (Post Prostatectomy)
Salvage Ultrahypofractionated Postoperative External Radiotherapy For Biochemical Recurrence
Recently, the Radiation Oncology Department at Fondazione IRCCS San Gerardo dei Tintori has been renovated and has been equipped with cutting edge technologies to treat prostate cancer.
- Trial name
- SUPERB (NCT06941363)
- Testing
- SDRT
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Milano Bicocca
Malignant Tumor of the Larynx
Stapler Versus Conventional Pharyngeal Repair After Total Larygectomy
This study was done to investigate the efficacy and safety of the linear stapler closure of the pharynx after total laryngectomy.
- Trial name
- NCT06256263
- Testing
- total laryngectomy
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Mansoura University
Colonic Neoplasms Malignant
Study of Oncological Outcomes of D3 Lymph Node Dissection in Colon Cancer
The purpose of this study is to determine wether D3 lymph node dissection gives superior oncological outcomes compared to standard D2 lymph node dissection in colon cancer
- Trial name
- COLD (NCT03009227)
- Testing
- Colonic resection with D2 lymph node dissection, Colonic resection with D3 lymph node dissection
- Where
- 12 sites in Russia
- Volunteers
- 780 people
- Sponsor
- N.N. Petrov National Medical Research Center of Oncology
Gastric Cancer
Robotic, Laparoscopic and Open Surgery for Gastric Cancer Compared on Surgical, Clinical and Oncological Outcomes
Gastric cancer represents a great challenge for health care providers and requires a multidisciplinary context in which surgery plays a main role.
- Trial name
- NCT02325453
- Testing
- Robotic Surgery, Laparoscopic Surgery, Open Surgery
- Where
- Italy
- Volunteers
- 7,000 people
- Sponsor
- International Study Group on Minimally Invasive Surgery for Gastric Cancer
Prostate Cancer, Treatment
Comparison H-FIRE and Laparoscopic RP in Treating Men With Localized Prostate Cancer
This trial is comparing the functional and oncological outcomes in treating men with prostate cancer between high-frequency irreversible electroporation and laparoscopic radical prostatectomy.
- Trial name
- NCT04278261
- Testing
- Focal therapy(high-frequency irreversible electroporation), laparoscopic radical prostatectomy
- Where
- China
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Shanghai East Hospital
Analgesia, Analgesia, Epidural
Postoperative Analgesia in Major Gynecological Cancer Surgeries
The aim of this study is to compare the effectiveness of epidural block or erector spinae plane block applied for postoperative analgesia in gynecological cancer surgeries.
- Conditions
- Analgesia, Analgesia, Epidural, ERAS
- Trial name
- NCT06424938
- Testing
- Patients who underwent epidural block, Patients who underwent erector spina plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Duygu Akyol
Kidney Neoplasms
Assessment of Oncological and Functional Outcomes After Robot Assisted Partial Nephrectomy Versus Laparoscopic Partial Nephrectomy
Currently, partial nephrectomy (PN) is considered as the gold standard treatment modality for small renal masses. In this setting, robot-assisted and conventional laparoscopic approaches are gaining more consensus every day.
- Trial name
- NCT02924922
- Testing
- Laparoscopic partial nephrectomy, Robot assisted partial nephrectomy, Conventional laparoscopic instruments
- Where
- Switzerland
- Volunteers
- 85 people
- Sponsor
- Luzerner Kantonsspital
Major Surgery
Long-term Enlarged Survival After an Enhanced Recovery Protocol (LESAS).
The main objective of this study is to analyze the impact on three years survival of an enhanced recovery program (PRI) after radical surgery for colorectal cancer.
- Trial name
- LESAS (NCT04305314)
- Testing
- PRI (Enhanced Recovery after surgery protocol)
- Where
- 12 sites in Spain
- Volunteers
- 750 people
- Sponsor
- Grupo Español de Rehabilitación Multimodal
Renal Cell Carcinoma
Oncological and Perioperative Outcomes of Laparoscopic Versus Robotic Partial Nephrectomy for Treatment of Renal Tumors.
partial nephrectomy offers lower renal function impairment and equivalent oncological survival outcomes compared with radical nephrectomy in those with T1 tumors.
- Trial name
- NCT06424080
- Testing
- laparoscopic partial nephrectomy, robotic partial nephrectomy
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Menoufia University
Cervical Cancers, Vaginal Cancers
Quality of Life and Sexuality After Pelvic Exenteration for Gynecologic Cancer
Pelvic exenteration is an exceptionally extensive and very rare surgical procedure, most commonly used in the treatment of locally recurrent cervical cancer among gynecological malignancies.
- Conditions
- Cervical Cancers, Vaginal Cancers, Vulvar Cancers, Endometrial Cancer
- Trial name
- NCT07594327
- Where
- Finland
- Volunteers
- 21 people
- Sponsor
- Tampere University Hospital