Clinical trials: Oncology Pain
Arthralgia, Breast Cancer
Cannabidiol (CBD) for Treatment of Aromatase Inhibitor-Associated Arthralgias
Study of Cannabidol to examine the safety and efficacy of 15 weeks of CBD in postmenopausal women with aromatase inhibitor-associated musculoskeletal symptoms (AIMSS).
- Trial name
- NCT04754399
- Testing
- Cannabidiol (CBD)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan Rogel Cancer Center
Multiple Myeloma, Compression Fracture of Vertebral Column
Evaluation of Vertebral Compression Fracture Fixation With RF Kyphoplasty in Patients With Multiple Myeloma
The objective of this post market clinical study is to collect prospective clinical data to confirm the efficacy of RF Kyphoplasty for the treatment of pathological fractures of the spine caused by multiple myeloma.
- Trial name
- MM (NCT01410929)
- Testing
- Kyphoplasty/Vertebral Augmentation (Device-StabiliT)
- Sponsor
- DFINE Inc.
Acupressure, Cancer Pain
The Effect of Acupressure and Reiki on Pain and Fatigue Levels
This research was conducted with the aim of determining the effect of levels of pain and fatigue of acupressure and Reiki application on cancer patients receiving palliative care.
- Conditions
- Acupressure, Cancer Pain, Fatigue
- Trial name
- NCT05473845
- Testing
- Acupressure intervention, Reiki intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people
- Sponsor
- Mardin Artuklu University
Orchiectomy, Spermatic Cord Block
Comparison of Spinal Anesthesia and Spermatic Cord Block for Bilateral Orchiectomy
The goal of this randomized controlled trial is to compare intraoperative pain score, Morphine consumption during 6 and 12 hour after surgery, and postoperative complications between SA and SCB groups in metastatic prostate…
- Conditions
- Orchiectomy, Spermatic Cord Block, Spinal Anesthesia, Pain Score
- Trial name
- NCT06313775
- Testing
- bilateral orchiectomy
- Where
- Thailand
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Sanpasitthiprasong Hospital
Chronic Neuropathic Pain
Surgical Treatment of Chronic Neuropathic Pain
Observational registry study assessing the subject's pain history and the impact of surgery for the treatment of chronic neuropathic pain by comparing post-operative outcomes (pain level, pain medication usage, quality of life…
- Trial name
- Rethink Pain (NCT04287075)
- Testing
- Surgical Management of Neuroma
- Where
- 4 sites in United States
- Volunteers
- 8 people
- Sponsor
- Axogen Corporation
Bowel Dysfunction, Constipation
Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain
Adults who are taking opioid therapy for persistent non-cancer pain and have resulting opioid-induced bowel dysfunction (OBD) will be randomized (1:1:1) to one 2 alvimopan arms, or to placebo.
- Trial name
- NCT00256932
- Testing
- alvimopan
- Where
- 200 sites in United States, Austria and 8 more
- Volunteers
- 518 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Postoperative Pain, Lung Cancer
Postoperative Pain Management on Patients Undergoing Lung Tumor Resection
Multimodal analgesia (MMA) is an essential part of Enhanced Recovery After Surgery (ERAS) protocol. The principle of MMA is to manage pain with analgesics of multiple classes acting on distinct target sites through different…
- Conditions
- Postoperative Pain, Lung Cancer, Lung Tumor
- Trial name
- NCT06397807
- Testing
- Dinalbuphine sebacate, Analgesic injectables, Enteral analgesics
- Volunteers
- 400 people
- Sponsor
- China Medical University Hospital
Thoracic Neoplasms, Lumbar Neoplasm
Local Radiofrequency Ablation Plus External Beam Radiation for the Treatment of Painful Thoracic and Lumbar Spine Tumors
This study looks at how well a combination of treatments helps reduce pain in people with tumors in the middle and lower back (thoracic and lumbar spine).
- Trial name
- NCT07479199
- Testing
- kyphoplasty with Osteocool
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Cancer, Pain
Study Evaluating Safety and Tolerability of Oxycodone in Patients With Moderate to Severe Cancer Pain
This study is to evaluate the safety and tolerability of oxycodone control-released (CR) and/or immediate-released (IR) use in patients with moderate to severe cancer pain in a 3-months period in Taiwan.
- Trial name
- STOP Pain (NCT03176121)
- Testing
- Oxycodone
- Where
- 10 sites in Taiwan
- Volunteers
- 73 people
- Sponsor
- Taiwan Mundipharma Pharmaceuticals Ltd.
Breast Neoplasms
Upper Limb Function After Breast Cancer Surgery: the Role of Post-operative Physical Therapy Intervention
Surgical treatments can cause late effects influencing activity of daily living, physical activity, and overall health. Late effects include persistent pain reported by 30 - 50% of women that underwent breast operations…
- Trial name
- NCT03389204
- Testing
- PHYSICAL THERAPY
- Where
- Israel
- Volunteers
- 160 people
- Sponsor
- Assuta Medical Center
Pain, Satisfaction
Randomized Controlled Trial Comparing Co2 vs. Air in Colonoscopy in Sedated Patients
CO2 insufflation instead of air for colonic distension in colonoscopy is considered to reduce pain after and during colonoscopy. There is limited data, that Co2 is similar effective in sedated patients.
- Trial name
- NCT00660296
- Testing
- Air insufflation use in colonoscopy, CO2 use in colonoscopy
- Where
- Austria
- Volunteers
- 300 people
- Sponsor
- Medical University of Vienna
Chronic Pain
Prospective Study About Clinical and Pharmacogenetic Safety of Opioid Use for Chronic Pain
Aim of this project is to customize the choice of the strong opioid in the treatment of cancer chronic pain through the identification of patient clinical history and pain characteristics, moreover in the analysis the…
- Trial name
- NCT00916890
- Testing
- Morphine, Oxycodone, Fentanyl
- Where
- 6 sites in Italy
- Volunteers
- 320 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Breast Cancer, Peripheral Neuropathies
Chemotherapy-Induced Peripheral Neuropathy-Essential Oil Intervention
This study will evaluate an oil blend with active ingredients for the reduction in chemotherapy-induced peripheral neuropathy in people with breast cancer.
- Trial name
- CIPN-EOI (NCT03449303)
- Testing
- EOI
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Augusta University
Breast Cancer
Musculoskeletal Pain in Postmenopausal, Early Breast Cancer Patients Receiving Aromatase Inhibitor Therapy - A Pilot Study
In 2005, the EBCIG demonstrated the efficacy of tamoxifen in improving overall survival in hormone receptor positive breast cancers.
- Trial name
- AIMS (NCT00653718)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Cancer Patients With Cancer Pain
DECLIC Patient Education Program : Assessment Through a Population Health Intervention Research Approach (LE DECLIC EPRI)
Cancer pain is a frequent symptom, reported by 20 to 70% of patients in any stage of the cancer disease : 60 to 70% in the advanced stage of the disease and 20 to 40% among the survivors.
- Trial name
- NCT04634097
- Testing
- Experimental group, standrad group
- Where
- 5 sites in France
- Volunteers
- 246 people
- Sponsor
- Institut Curie
Degenerative Disc Disease, Herniated Disc
Bone Graft Materials Observational Registry
A multi-center, prospective, observational patient registry to collect information on the clinical outcomes and "real world" use of approved and commercially available bone graft substitutes, autograft and allograft.
- Conditions
- Degenerative Disc Disease, Herniated Disc, Spinal Stenosis, Spondylolithesis
- Trial name
- APPROACH-001 (NCT00974623)
- Testing
- Bone graft substitute, autograft or allograft
- Where
- 14 sites in United States, Hungary and 1 more
- Volunteers
- 329 people
- Sponsor
- Baxter Healthcare Corporation
Pain Related to Cancer
Evaluation of the Efficacy and Safety of Two Methadone Titration Methods for the Treatment of Cancer-related Pain With Inadequate Pain Relief or Intolerable Side Effects When Treated With Level 3 Opioids.
This is a multicentric, randomized, open-label, phase IIIb national study, to evaluate the clinical effects (success/failure) of methadone for the treatment of cancer-related-pain in patients with inadequate pain relief or…
- Trial name
- EQUIMETH2 (NCT01793480)
- Testing
- Methadone
- Where
- 16 sites in France
- Volunteers
- 146 people
- Sponsor
- RECORDATI GROUP
Pain
Pharmacokinetics & Safety of Diclofenac Potassium Oral Solution in Ped. Subjects (2-12 Yrs) With Mild-Mod. Acute Pain
As part of the Pediatric Research Equity Act (PREA) commitment, the objectives of the study are to characterize the pharmacokinetic (PK) profile and to determine the safety and tolerability of diclofenac potassium oral solution…
- Trial name
- NCT02287350
- Testing
- diclofenac potassium oral solution
- Where
- 5 sites in United States
- Volunteers
- 51 people
- Sponsor
- Depomed
Advanced Cancer, Pain
Safety Evaluation of Bioactive Glass Based Bone Cement Combined With Ultrasound in Implantation for Metastatic Bone Tumors
This study is evaluating the safety of using bioactive glass-containing bone cement combined with ultrasound during surgery for patients with metastatic bone tumors.
- Trial name
- SE-BGCU-MBT (NCT07540468)
- Testing
- Bioactive Glass Bone Cement + Ultrasound
- Volunteers
- 8 people
- Sponsor
- Liao Yun
Head and Neck Cancer
A Trial of Nimotuzumab and Pinkiller Efficacy and Pain in Advanced Head and Neck Squamous Cell Carcinoma
The purpose of this study is to investigate the impact of combining Nimotuzumab with analgesic agents on pain management outcomes, as well as the effectiveness and safety profile of this therapeutic combination in the…
- Trial name
- NCT06879691
- Testing
- Nimotuzumab, cis-platinum, IMRT combine with cisplatin concurrent chemotherapy
- Where
- China
- Volunteers
- 171 people
- Sponsor
- Biotech Pharmaceutical Co., Ltd.