Clinical trials: Ondansetron
Chemotherapy-Induced Nausea and Vomiting
Efficacy and Safety of Palonosetron Intravenous in Prevention of Chemotherapy Induced Nausea and Vomiting in Pediatric Patients
The primary objective is to evaluate the efficacy of two different doses of IV palonosetron in the prevention of chemotherapy induced nausea and vomiting in MEC and HEC patients through 120 hours after start of chemotherapy in…
- Trial name
- NCT01442376
- Testing
- Palonosetron, Ondansetron
- Where
- 67 sites in United States, Argentina and 14 more
- Volunteers
- 502 people
- Sponsor
- Helsinn Healthcare SA
Hernia, Inguinal
Efficacy of Co-Spinal Ondansetron In Inguinal Herniorrhaphy
Ondansetron, a selective serotonin 5-HT3 receptor antagonist, is well known for its antiemetic effects. However, its ability to reduce hypotension during spinal anesthesia has recently sparked great interest.
- Trial name
- NCT06850740
- Testing
- Ondansetron 8mg, Normal Saline
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Suez Canal University
Juvenile Idiopathic Arthritis
The Ondansetron Premedication Trial in Juvenile Idiopathic Arthritis
Far too many kids and families live in dread over the weekly nausea and vomiting caused by methotrexate - a medicine that controls joint swelling in Juvenile Arthritis patients.
- Trial name
- OPT-JIA (NCT04169828)
- Testing
- Methotrexate, Ondansetron, Folic/folinic acid
- Where
- 11 sites in Canada
- Volunteers
- 52 people
- Sponsor
- University of British Columbia
Alcohol Abuse, Alcoholism
Ondansetron for the Treatment of Heavy Drinking Among Emerging Adults
This study will evaluate the efficacy of ondansetron + BASICS Plus in reducing severe or binge drinking among emerging adults. BASIC Plus (Brief Alcohol Screening and Intervention for College Students) has been the most validated…
- Trial name
- NCT00890149
- Testing
- Ondansetron, BASICS Plus
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Maryland, Baltimore
Pruritus, Nausea/Vomiting
Does IV Ondansetron Prevent Pruritus After Intrathecal Morphine in Pediatric Patients?
This is a prospective randomized, double-blind, placebo-controlled study to compare the incidence and intensity of ITM-induced pruritus and nausea/vomiting using pre-emptive IV ondansetron, followed by scheduled Around The Clock…
- Trial name
- NCT03262038
- Testing
- Ondansetron
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Michigan
Preeclampsia, Spinal Anesthesia-Induced Hypotension
Dexamethasone Versus Ondansetron for Preventing Post-Spinal Hypotension in Preeclampsia
This study compares the efficacy and safety of intravenous dexamethasone versus intravenous ondansetron in preventing low blood pressure (hypotension) following spinal anesthesia in pregnant women with preeclampsia undergoing…
- Conditions
- Preeclampsia, Spinal Anesthesia-Induced Hypotension, Cesarean Section
- Trial name
- NCT07793760
- Testing
- Dexamethasone, Ondansetron
- Volunteers
- 110 people
- Sponsor
- Assiut University
Nausea and Vomiting
the Efficacy and Safety of Ondansetron Oral Soluble Pellicles
The name of this prospective study is a multicenter, open-label, randomized controlled clinical study of the efficacy and safety of Ondansetron Oral Soluble Pellicles for the prevention of delayed nausea and vomiting induced by…
- Trial name
- NCT06282211
- Testing
- Ondansetron Oral Soluble Pellicles
- Where
- China
- Volunteers
- 184 people
- Sponsor
- The First Affiliated Hospital of Xinxiang Medical College
Postoperative Nausea and Vomiting, Post Operative Pain
Effect of Dexmedetomidine on Prevention of Postoperative Nausea and Vomiting in Children
this study will aim to evaluate the effects of dexmedetomidine, dexamethasone and Ondansetron on the prevention of postoperative nausea and vomiting in children undergoing dental rehabilitation surgery.
- Conditions
- Postoperative Nausea and Vomiting, Post Operative Pain, Emergence Delirium
- Trial name
- NCT05124067
- Testing
- Dexamethasone, Ondansetron, Dexmedetomidine
- Where
- Saudi Arabia
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Tanta University
Nausea and Vomiting in Pregnancy
Effect of Moringa Oleifera, Zingiber Officinale, and Curcuma Xanthorrhiza Extracts for Nausea and Vomiting in First-Trimester Pregnancy
This retrospective cohort study will evaluate the association between adjunctive Moringa oleifera, Zingiber officinale, and Curcuma xanthorrhiza extracts and changes in Pregnancy-Unique Quantification of Emesis and Nausea (PUQE)…
- Trial name
- NCT07833371
- Where
- Indonesia
- Volunteers
- 65 people
- Sponsor
- Maranatha Christian University
Spinal Anaesthetic
Granisteron Versus Ondansetron for Prophylaxis Against Post-Spinal Anesthesia Shivering: a Randomized Controlled Study
3. Scientific committee approval (Was it scientifically approved by the department?) Yes Date of approval: Sunday ,1ST September,2019 Background and Rationale: Regional anesthesia is commonly associated with intraoperative…
- Trial name
- NCT04294992
- Testing
- Ondansetron 8mg
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Kasr El Aini Hospital
Postoperative Vomiting
Postoperative Vomiting in Children - Is Dextrose an Effective Prophylactic Anti-emetic?
The aim of this study was to investigate the efficacy of intraoperative intravenous dextrose in preventing POV in pediatric population undergoing dental day surgery.
- Trial name
- DEXPO (NCT01912807)
- Testing
- Dextrose (D5NS), Ondansetron (Control)
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- University of Saskatchewan
Cancer
Ondansetron Plus Dexamethasone With or Without Metoclopramide as Antiemetic Prophylaxis After Receiving Cisplatin
The objective of this study is to assess the efficacy and tolerability of metoclopramide added to standard antiemetic regimen for prophylaxis of cisplatin-induced emesis.
- Trial name
- NCT01093690
- Testing
- metoclopramide
- Where
- Thailand
- Volunteers
- 162 people
- Sponsor
- Mahidol University
Healthy
Bioequivalence Study for Ondansetron Hydrochloride Tablets 8 mg Under Fed Condition
This is an open label, balanced, randomized, two-treatment, two-period, two sequence,single dose, crossover, oral bioequivalence study.
- Trial name
- NCT01511718
- Testing
- Ondansetron Hydrochloride
- Where
- India
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Postoperative Nausea and Vomiting
Dexamethasone and Ondansetron Versus Placebo for Postoperative Nausea and Vomiting
The investigators want to test if it is indicated to associate dexamethasone and ondansetron in obese patients having bariatric surgery under total intra-venous closed-loop anesthesia.
- Trial name
- Loop-NVPO (NCT01876290)
- Testing
- Dexamethasone and Ondansetron
- Where
- France
- Volunteers
- 122 people
- Sponsor
- Hopital Foch
Vomiting
Hyoscine Butyl-bromide Versus Ondansetron for Nausea and Vomiting During Cesarean Section Under Spinal Anesthesia
overall incidence of intraoperative nausea and vomiting(IONV) during regional anesthesia for cesarean section is extremely variable, up to 80 percent , depending on the anesthetic technique used (spinal, epidural or combined…
- Trial name
- NCT04785118
- Testing
- Hyoscine N Butylbromide, Ondansetron, Saline
- Where
- Egypt
- Volunteers
- 165 people
- Sponsor
- Assiut University
Myocardial Repolarization
The Effects of the Anti Nausea Drugs Droperidol and Ondansetron on the Way the Heart Recovers Between Beats
We are investigating a new technique for testing the effect of drugs on electrical activity in the heart. Disturbances of this electrical activity can cause life-threatening changes to heart rhythms.
- Trial name
- NCT00624208
- Testing
- droperidol and saline, ondansetron and saline, droperidol and ondansetron
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia