Clinical trials: Only Child
Indications for Laparoscopic Thoracic and Abdominal Surgery in Children, Congenital or Acquired Surgical Conditions Requiring Minimally Invasive Surgery in Children
Clinical Trial on Safety and Efficacy of Thoracoabdominal Endoscopic Surgical System for Pediatric Surgery
This is a prospective, multi-center, single-arm, target-value clinical trial conducted to evaluate the safety and effectiveness of the Thoracic and Abdominal Endoscopic Surgery System (model WJ-SR01-200) in pediatric surgical…
- Conditions
- Indications for Laparoscopic Thoracic and Abdominal Surgery in Children, Congenital or Acquired Surgical Conditions Requiring Minimally Invasive Surgery in Children, Pyeloplasty, Ureteral Reimplantation
- Trial name
- NCT07530133
- Testing
- Thoracic and Abdominal Endoscopic Surgery System
- Where
- 3 sites in China
- Volunteers
- 64 people
- Sponsor
- Hangzhou Kangji Weijing Medical Robotics Co., Ltd.
Cerebral Palsy, Postural; Defect
The Effect of Dynamic Elastomeric Fabric Orthosis (DEFO) on Sitting Balance and Gross Manuel Dexterity in Cerebral Palsy
To evaluate the effects and feasibility of lycra based compression garment called Stabilizing Pressure Input Orthosis (SPIO) vest on posture and balance during sitting and gross manuel dexterity, parent satisfaction with the…
- Trial name
- NCT03191552
- Testing
- SPIO, conventional exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Marmara University
Dental Pain
Buffered Local Anesthetic
The purpose of this research study is to compare responses in children during dental injections of local anesthetic (used for numbing), while children are under deep sedation (breathing on their own, often with a loss of…
- Trial name
- NCT05757648
- Testing
- Non-buffered Anesthetic, Buffered Anesthetic, Onset
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Autism Spectrum Disorders
Single Dose Double-blind, Placebo-controlled Cross-over (SDDBPCCO) Shiftability Study, Will be Followed by a 10-week Open-label Study With Arbaclofen (4 Weeks of Titration and Then 6 Weeks of Active/Stable Treatment). The Effects of Arbaclofen on Target EEG and ERG Metrics Will be Associated With th
study with arbaclofen (4 weeks of titration and then 6 weeks of active/stable treatment). The effects of arbaclofen on target EEG and ERG metrics will be associated with the clinical response in measures of social and general…
- Trial name
- NCT07655115
- Testing
- Arbaclofen
- Where
- 5 sites in France, Spain
- Volunteers
- 103 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Children, Only, Vestibular Function
Normative Data of Vestibular and Postural Function in Danish Children
The goal of this age-based cohort study is to provide normative data of vestibular function in the general Danish pediatric population.
- Trial name
- VASIC (NCT06229730)
- Testing
- video Head Impulse Test, Cervical Vestibular Evoked Myogenic Potential, Ocular Vestibular Evoked Myogenic Potential
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Gødstrup Hospital
Periodontal Disease
Study Aimed at Detecting Potential Abuse of Nitrous Oxide in Children During Dental Care
The aim of this study is to evaluate the potential risk of abusive behavior for children in care using nitrous oxide for dental care.
- Trial name
- MEOPAeDent (NCT02894463)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 76 people
- Sponsor
- Nantes University Hospital
Epilepsy
Open-label Study of Levetiracetam Intravenous Infusion in Children (4-16 Years Old) With Epilepsy
Keppra injection is approved in the US as adjunctive therapy in the treatment of partial onset seizures in adults with epilepsy.
- Trial name
- NCT00535392
- Testing
- Levetiracetam
- Where
- 25 sites in United States, Belgium and 4 more
- Volunteers
- 33 people
- Sponsor
- UCB Pharma
CMV, AdV Infection
Phase 3 Randomized Trial for Refractory ADV or CMV Infection With Family Matched CTLs and Standard of Care (SOC) vs SOC Alone
Patients with refractory ADV or CMV infection post allogeneic stem cell transplant will be randomized to either Family donor-derived viral specific cytotoxic T lymphocytes (CTLs) plus standard of care (SOC) vs SOC alone.
- Conditions
- CMV, AdV Infection, AdV Reactivation, Adenovirus
- Trial name
- NCT07225972
- Testing
- Standard of Care Antiviral medications, Viral CTLs
- Where
- 2 sites in United States
- Volunteers
- 138 people
- Sponsor
- New York Medical College
Smoking Reduction, Asthma in Children
Early Life Intervention in Pediatrics Supported by E-health - SMOKE
Unrestricted parental smoking habits are lifestyle risk behaviors associated with chronic, systemic inflammation, which promotes the pathogenesis of non-communicable diseases (NCDs).
- Conditions
- Smoking Reduction, Asthma in Children, Wheezing, Non-Communicable Disease
- Trial name
- ELIPSE-II (NCT06311162)
- Testing
- Life-Style app
- Where
- Switzerland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pain
A Study to Evaluate Ibuprofen (IBU) 62.5 mg and Acetaminophen (APAP) 125 mg/5 ml in an Oral Liquid Suspension Fixed-Dose Combination Product in Children Aged 6 to 11 Years
The purpose of this study will be to characterize the pharmacokinetic (PK) profile of the Fixed-Dose Combination (FDC) IBU 62.5 milligram (mg)/APAP 125 mg per 5 milliliter (mL) suspension in children 6 to 11 years of age…
- Trial name
- NCT07632274
- Testing
- Test Product
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- HALEON
Status Epilepticus, Coma
Rapid-Response EEG in Children With Suspected Status Epilepticus
Seizures are common in children (~350 per 100,000 patients per year) and require immediate medical attention. If the seizure is prolonged (> 5 minutes) it is called status epilepticus and delayed treatment leads to higher risk in…
- Trial name
- RECS (NCT06564662)
- Testing
- Rapid Response EEG
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Hospital at Montefiore
Adenovirus
Effectiveness of a Single Dose of Betamethasone in Children With Symptomatic Adenovirus Infection
The goal of this double-blind, Placebo-controlled Randomized Study is to assess if a single dose of betamethasone in children with febrile adenoviral infection works well in achieving an early fever regulation.
- Trial name
- Adeno-beta (NCT06299813)
- Testing
- Bentelan
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Child, Only, Essential Hypertension
Juvenile Essential Arterial Hypertension and Vascular Function
The main goal of this study is to investigate the association of the juvenile essential arterial hypertension with systemic micro- and macrovascular reactivity and cerebral vascular function, and to examine the potential impact…
- Trial name
- NCT05109013
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Helicobacter Pylori Infection, Children, Only
Treatment Adherence And Influencing Factors in Children With Helicobacter Pylori Infection During Eradication Therapy
The aim of this study is to describe the current status of treatment adherence in children with Helicobacter pylori infection, understand the medication literacy, medication beliefs of the children, knowledge of H.
- Trial name
- NCT06396780
- Where
- China
- Volunteers
- 233 people
- Sponsor
- Wei XIA, PhD
Myopia
Myopia Control in Children: Comparison of Defocus Incorporated Multiple Segments® Lenses Versus Atropine 0.05% Eyedrops
Myopia is the most common refractive disorder in the world. Many strategies have been developed to control myopia in children. Among them, the instillation of low-concentration atropine eyedrops has been proven to be effective in…
- Trial name
- ATROSMART (NCT05062031)
- Testing
- Defocus Incorporated Multiple Segments® (DIMS®) lenses, Atropine 0.05% eyedrops, Monofocal lenses
- Where
- France
- Volunteers
- 116 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Feeding Behaviors
Effects of Portion Size and Energy Density of a Single Meal in Preschool Children
This study investigates the effect of varying both energy density and portion size of all foods at lunch on preschool children's intake.
- Trial name
- NCT02299531
- Testing
- Varying meal energy density and portion size
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Penn State University
Multisensory Stimulation, Child, Only
Multisensory Stimulation on Postoperative Pain, Physiological Parameters and Fear in Children
It is known that non-pharmacological methods are effective in reducing pain in children and that they increase the effectiveness of drugs when used together with analgesics.
- Conditions
- Multisensory Stimulation, Child, Only, Postoperative Pain, Fear
- Trial name
- NCT06237894
- Testing
- Multisensory Stimulation
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bilecik Seyh Edebali Universitesi
Child, Only, Quality of Life
Evaluation of The Effect of Crowns Applied With Hall Technique on Occlusion
This study aims to evaluate and compare the change on occlusion after placing stainless steel crowns (SCC) using Hall technique and conventional technique in children between the ages of 5-8.
- Trial name
- NCT06220383
- Testing
- Hall technique, Conventional technique
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Health Care Utilization, Mental Health Impairment
Transitioning Young Patients' Health Care Trajectories
The project aims to transition the approach used to care for children with complex conditions and care pathways into a more holistic and coordinated model.
- Conditions
- Health Care Utilization, Mental Health Impairment, Child, Only, Multi-morbidity
- Trial name
- NCT04652154
- Testing
- Transitioning young patients' health care trajectories
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Haukeland University Hospital
Chemotherapy Induced Mucositis, Mouth Pain
A Study to Characterize the Pharmacokinetics and Tolerability of Buprenorphine Patches in Children With Moderate to Severe Mouth Pain
The purpose of this study is to characterize the pharmacokinetics and tolerability of buprenorphine patches in children who require opioid pain relief for moderate to severe mouth pain.
- Trial name
- BUP1501 (NCT00947466)
- Testing
- Buprenorphine
- Where
- 2 sites in Denmark, United Kingdom
- Volunteers
- 25 people
- Sponsor
- Mundipharma Research Limited
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