Clinical trials: Only Child
Adiposity, Childhood Obesity
Early Life Intervention in Pediatrics Supported by E-health
Childhood obesity in early life contributes to the development of specific NCDs, i.e. adult obesity. Unhealthy diet and low level of physical activity are lifestyle risk behaviors associated with chronic, systemic inflammation…
- Conditions
- Adiposity, Childhood Obesity, Adolescent Obesity, Non-communicable Disease
- Trial name
- ELIPSE-I (NCT06208345)
- Testing
- Life-Style app
- Where
- Switzerland
- Volunteers
- 148 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Stress, Child, Only
Evaluating the Effectiveness of the Calm Moments Cards Program Implemented by School Personnel
We explored the meaning and outcomes of a 4-month program designed to build capacity of school personnel in implementing evidence-based strategies for reducing stress and promoting mental well-being among students in school…
- Trial name
- CMC (NCT03173209)
- Testing
- professional development in Calm Moments Cards program
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Cleveland State University
Asymmetric Hearing Loss, Single-sided Deafness
Cochlear Implantation in Children With Asymmetric Hearing Loss or Single-Sided Deafness Clinical Trial
This is a two-phase study that compares performance growth pre-implant with current hearing aid (HA) technology versus post-implant with a cochlear implant (CI) in children with either asymmetric hearing loss (AHL) or…
- Conditions
- Asymmetric Hearing Loss, Single-sided Deafness, Unilateral Deafness
- Trial name
- NCT04793412
- Testing
- Cochlear Implant
- Where
- 5 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Epilepsy
Open-label Study of Levetiracetam Intravenous Infusion in Children (1 Month-4 Years Old) With Epilepsy
Keppra injection is approved in the US as adjunctive therapy in the treatment of partial onset seizures in adults with epilepsy.
- Trial name
- NCT00505934
- Testing
- Levetiracetam
- Where
- 23 sites in United States, Belgium and 4 more
- Volunteers
- 19 people
- Sponsor
- UCB Pharma SA
Balance
Dual-Task Training for Balance and Fine Manual Control in Unilateral CP
This trial will evaluate the impact of a dual-task training program on children aged 6-8 years with unilateral cerebral palsy. eighty four participants will be randomized into dual-task and single-task groups, with the dual-task…
- Trial name
- NCT07178782
- Testing
- Dual-Task Training Program, rehabilitation program
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Badr University
Postoperative Nausea and Vomiting
Aromatherapy for Postoperative Nausea and Vomiting in Children
Postoperative nausea and vomiting (PONV) is one of the most common postoperative complications of general anesthesia in pediatrics. Pediatric rates of nausea and vomiting are approximately double those of adult patients.
- Trial name
- NCT02663154
- Testing
- Aromatherapy inhaler, Saline inhaler
- Volunteers
- 39 people
- Sponsor
- Stuart Wright
Diabetes Mellitus, Type I
Effect of Advanced Hybrid Closed Loop System, MiniMed 780G in Newly Diagnosed Children and Adolescents With Type 1 Diabetes on Glycemic Control and Patient Reported Outcomes Compared to Standard Insulin Therapy Historical Data (AHCL in New Onset T1D Children Study)
The objective of this study is to evaluate glycemic control of users of the AHCL system MiniMed 780G with GS4 calibration-free sensor in children and adolescents with newly diagnosed T1D implemented directly upon T1D diagnosis in…
- Trial name
- NCT06919029
- Testing
- Advanced Hybrid Closed Loop from onset of type 1 diabetes in children
- Where
- Greece
- Volunteers
- 30 people
- Sponsor
- National and Kapodistrian University of Athens
Tonsillectomy
A Study of BiZact™ on Children and Adolescents Undergoing Tonsillectomy
The purpose of this study is to assess safety and performance with the use of the BiZact™ device in tonsillectomy procedures in children and adolescents.
- Trial name
- NCT03266094
- Testing
- BiZact™: A bipolar instrument for tonsillectomies
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Medtronic - MITG
Congenital Solitary Kidney
Long Term Outcome of Congenital Solitary Kidney
Congenital solitary kidney (CSK) is a disorder caused by an abnormal development of one of the two kidneys. The reported incidence ranges between 1:450-3200. It is debated whether CSK is a benign condition or not.
- Trial name
- CSKP (NCT01831141)
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Dental Anxiety, Children, Only
Effect of Parental Absence on Child's Dental Anxiety and Behaviors During Dental Treatment
The basis of pediatric dentistry is to provide cooperation in children with various behavioral management techniques. The presence or absence of the parent during dental treatments can be used to ensure the child's compliance…
- Conditions
- Dental Anxiety, Children, Only, Dental Caries
- Trial name
- NCT05125731
- Testing
- Parental absence, Parental visual support, Parental presence
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Chronic Hepatitis C Infection, Compensated Cirrhosis
A Study to Evaluate the Safety and Efficacy of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir in Adults With Genotype 1b Chronic Hepatitis C Virus (HCV) Infection and Cirrhosis
The purpose of this study was to evaluate the safety and efficacy of ombitasvir/ paritaprevir/ ritonavir and dasabuvir in adults with genotype 1b chronic hepatitis C virus (HCV) infection and cirrhosis.
- Trial name
- TURQUOISE-III (NCT02219503)
- Testing
- Ombitasvir/Paritaprevir/Ritonavir, Dasabuvir
- Volunteers
- 60 people
- Sponsor
- AbbVie
Malignancies, Cardiovascular Diseases
Cancer Therapy-related Cardiac Dysfunction Occuring in Children Treated by Anticancer Drugs for Malignancies
Little is known about cancer therapy-related cardiac dysfunction occuring in children treated by anticancer drugs for malignancies.
- Conditions
- Malignancies, Cardiovascular Diseases, Children, Only
- Trial name
- NCT05602103
- Testing
- use of anticancer drugs in monotherapy or in combination therapy
- Volunteers
- 10,000 people
- Sponsor
- University Hospital, Caen
Pulpectomy, Irreversible Pulpitis
Clinical and Radiographic Outcomes of Rotary Instrumentation in Primary Molars
This study will evaluate the clinical and radiographic outcomes of rotary versus manual pulpectomy in children with irreversible pulpitis.A single-visit pulpectomy will be performed for all patients.
- Trial name
- NCT07319741
- Testing
- Rotary Instrumentation, Manual Instrumentation
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Anfal mohamed elmotaz almogtaba
Tonsillopharyngitis, Rhinopharyngitis
Trial To Assess Efficacy and Safety of PediaFlu® in Children With Acute Tonsillopharyngitis / Rhinopharyngitis
Sore throat or acute tonsillopharyngitis, often referred to as angina catarrhalis in Central and Eastern Europe, affects mainly children, adolescents and young adults and represents one of the most common reasons to consult a…
- Trial name
- NCT04899401
- Testing
- Standard of care + PediaFlù®, Standard of care
- Where
- 3 sites in Romania
- Volunteers
- 130 people
- Sponsor
- Pediatrica S.r.l
Pain, Long-bone Fractures
Analgesic Efficacy of Morphine Alone or Combined With Paracetamol and/or Ibuprofen for Long-bones Fractures in Children
The main objective of this study is to evaluate the efficacy of two drugs: paracetamol and ibuprofen in association with morphine, compared with morphine alone on analgesia in children seen in the emergency department for a…
- Trial name
- MORPHAPAIN (NCT02477007)
- Testing
- Paracetamol, Ibuprofen, paracetamol + ibuprofen
- Where
- France
- Volunteers
- 304 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
HIV Infections
Pharmacokinetics Study on Nevirapine Resistance in Tanzania
Primary pharmacokinetics of single dose nevirapine the effect of single dose carbamazepine on the pk of single dose nevirapine resistance against nevirapine before and after.
- Trial name
- NCT00294892
- Testing
- carbamazepine and nevirapine, Nevirapine
- Where
- Tanzania
- Volunteers
- 144 people
- Sponsor
- Radboud University Medical Center
Type 1 Diabetes Mellitus
Protection Against Pneumococcal Infection in Children With T1DM
Children/ young people with diabetes may be at a higher risk of acquiring certain infections. These infections include those caused by a bacterium called the pneumococcus which can cause pneumonia, meningitis and ear infections.
- Trial name
- T1DM (NCT01939522)
- Testing
- 13-valent pneumococcal conjugate vaccine (PCV13)
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Oxford
Clinical Pharmacology
Study on the Safety of BAY 63-2521, How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Drug Given as a Single Oral Dose of 1 mg Tablet in Participants With Impaired Liver Function and Healthy Participants Matched for Age-, Gender-, and Weight
BAY 63-2521 is intended to be used for a disease that affects the blood flow through the lungs. Renal impairment is a common condition in patients with this disease.
- Trial name
- NCT04366622
- Testing
- Riociguat (Adempas, BAY 63-2521)
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bayer
Pediatric, Bacterial Infections
A Pharmacokinetic Study of LP-001 in Children With a Bacterial Infection
The purpose of this study is to determine the pharmacokinetic profiles of LP-001, an amoxicillin and clavulanate formulation compared to the pharmacokinetic profiles of Augmentin ES-600 for use in pediatric patients with a…
- Trial name
- NCT05584683
- Testing
- Amoxicillin potassium clavulanate, Amoxicillin potassium clavulanate (Augmentin ES-600)
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Kaizen Bioscience Co.
Helminthiasis, Ascaris Infection
Soil-transmitted Helminth Reinfection Rates After Single and Repeated School Hygiene Education
Soil-transmitted helminth (STH) infections caused by Ascaris lumbricoides, Trichuris trichiura, or hookworm, affect approximately 1.5 millions individuals primarily in tropical and subtropical regions.
- Conditions
- Helminthiasis, Ascaris Infection, Trichuris Infection, Hookworm Infections
- Trial name
- NCT04227834
- Testing
- Health hygiene education
- Where
- Indonesia
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- Universitas Sumatera Utara