Clinical trials: Only Child
Acquired Brain Injury
Exploring the Use of the CO-OP With Children With EF Functions Deficits Following ABI
Purpose: Acquired brain injury (ABI) in childhood are the cause of disabling motor, cognitive and behavioural disorders, with severe consequences on the later development of autonomy and learning, with long-term repercussions on…
- Trial name
- NCT04718688
- Testing
- CO-OP rehabilitation
- Where
- France
- Volunteers
- 2 people
- Sponsor
- Hopitaux de Saint-Maurice
Congenital Heart Disease, Physical Inactivity
Exergame-Based Physical Activity Promotion for Children and Adolescents With Congenital Heart Disease
The goal of this clinical trial is to learn whether a Nintendo Switch-based exergame physical activity program can help children and adolescents with congenital heart disease increase their physical activity.
- Trial name
- ExPACE-CHD (NCT07593118)
- Testing
- Nintendo Switch-Based Exergame Physical Activity Promotion Intervention
- Where
- China
- Volunteers
- 13 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Hemophilia A
Study of Biostate for Treatment of Children With Hemophilia A Complicated by Antibody Development
This is a clinical study to investigate how well Biostate works in treatment of male patients below the age of 12 years who have a clotting factor deficiency that is aggravated by the development of antibodies.
- Trial name
- NCT01445197
- Testing
- Biostate
- Where
- 7 sites in Austria, Germany and 3 more
- Volunteers
- 1 people
- Sponsor
- CSL Behring
Haemophilus Influenzae Type b (Hib) Infection
Immunogenicity and Safety of a Monovalent Glycoprotein-Conjugated (Diptheria Toxin -CRM197) Hib Vaccine in 13-59 Months Old Healthy Children
This study will evaluate the safety and immunogenicity of single dose of two commercially available vaccines used to prevent Haemophilus influenzae type b infections in children 13-59 months of age.
- Trial name
- NCT01125527
- Testing
- Monovalent glyco-conjugated vaccine against Haemophilus influenzae type b (Hib), Tetanus toxoid polysaccharide-conjugated vaccine against Haemophilus influenzae type b (Hib)
- Where
- China
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Infectious Disease, Febrile Illness
A Rapid Triage Test to Improve Risk-stratification of Febrile Children (EChiLiBRiST, Clinical Trial 1, Outpatients)
The overall aim of the study is to provide evidence that introducing novel biomarkers evaluation at triaging (first clinical assessment), in combination with IMCI-based guidelines (SoC), is a viable strategy to enhance rapid and…
- Conditions
- Infectious Disease, Febrile Illness, Child, Only
- Trial name
- NCT06422338
- Testing
- IMCI-enhanced by suPAR levels (SoC + suPAR POC)
- Where
- 2 sites in Gabon, Mozambique
- Volunteers
- 5,212 people
- Sponsor
- Barcelona Institute for Global Health
Acute Pyelonephritis, Complicated Urinary Tract Infection
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Meropenem-Vaborbactam in Children With Complicated Urinary Tract Infection, Including Acute Pyelonephritis
The primary objective of the study is to assess the safety and tolerability of meropenem-vaborbactam administered by intravenous (IV) infusion in children 3 months and above to less than 12 years with complicated urinary tract…
- Trial name
- NCT06672978
- Testing
- Meropenem-Vaborbactam, Antibiotics
- Where
- 26 sites in United States, Bulgaria and 4 more
- Volunteers
- 66 people
- Sponsor
- Rempex (a wholly owned subsidiary of Melinta Therapeutics, LLC)
Healthy Volunteer
AZD7325 Multiple Ascending Dose Study
This is a study to evaluate safety, tolerability, PK and PD effects of orally administered AZD7325 after single and repeated ascending doses.
- Trial name
- MAD (NCT00681915)
- Testing
- AZD7325
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Asthma Exacerbation, Children
A Comparative Study of Adding Ipratropium to Salbutamol for the Treatment of Asthma Attack in Children
The goal of this clinical trial was to determine if adding ipratropium bromide to salbutamol improves asthma treatment in children.
- Trial name
- NCT06918418
- Testing
- Salbutamol (Ventolin®), salbutamol + ipratropium bromide nebules
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Children's Hospital and Institute of Child Health, Multan
Diarrhoea
Long-Term Immunogenicity of the altSonflex1-2-3 Shigella Vaccine in African Children
The current study is a follow-up to 2 previous parent studies, a dose-selection study with 3 different dose-levels of the altSonflex1-2-3 vaccine in a schedule of 3 vaccinations (H06_01TP study [NCT05073003, 212149]) and a study…
- Trial name
- H06_04TP (NCT07320716)
- Testing
- AltSonflex1-2-3, Menveo, Infanrix hexa
- Volunteers
- 528 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Solid Tumor, Lymphoma
Durvalumab in Pediatric and Adolescent Patients
This clinical trial is the first clinical trial to study Durvalumab, a checkpoint inhibitor which stimulates the patient's own immune system to act against cancer cells in children and adolescents.
- Conditions
- Solid Tumor, Lymphoma, Central Nervous System Tumors
- Trial name
- NCT02793466
- Testing
- Durvalumab; MEDI4736
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Leo Mascarenhas
Neuroblastoma
A Study of LY3295668 Erbumine in Participants With Relapsed/Refractory Neuroblastoma
The reason for this study is to see if the study drug LY3295668 erbumine is safe in participants with relapsed/refractory neuroblastoma.
- Trial name
- NCT04106219
- Testing
- LY3295668 Erbumine, Topotecan, Cyclophosphamide
- Where
- 17 sites in United States, Australia and 7 more
- Volunteers
- 71 people
- Sponsor
- Eli Lilly and Company
Autism Spectrum Disorder
tDCS on Working Memory (WM) in Adults With ASD
This study will involve an experiment in individuals with Autism Spectrum Disorder (ASD) comparing their performance on a working memory task before, during and after non-invasive brain stimulation (tDCS) compared to a control…
- Trial name
- NCT03255837
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- NHS Greater Glasgow and Clyde
Idiopathic Short Stature
A Study (Phase 1b/2) of GenSci134 in Children With Idiopathic Short Stature (ISS)
This study comprises two phases: Phase Ib and Phase II. Phase Ib is a multicenter, randomized, open-label, active-controlled, single-dose, dose-escalation study to evaluate the safety, tolerability, PK/PD profile, and…
- Trial name
- NCT07450053
- Testing
- GenSci134 Injection, Recombinant Human Growth Hormone Injection(Norditropin® FlexPro®)
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Liver Cirrhosis
Midodrine Plus Albumin Versus Midodrine Alone to Prevent Cirrhosis Related Complications in Children With Cirrhosis and Ascites
Children with decompensated cirrhosis are more prone to develop various complications. The pathogenesis of cirrhotic complications (ascites, hyponatremia, acute kidney injury) includes release of vasodilatory molecules like…
- Trial name
- NCT06091345
- Testing
- Midodrine, albumin, Standard Medical Treatment
- Where
- India
- Volunteers
- 61 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Anxiety, Child, Only
The Impact of Preprocedural Animation About Echocardiography Display and Kaleidoscope Display on Anxiety in Children
Objective: The study was conducted for the purpose of determining the effect of making children aged 5 to 12 years watch a cartoon about echocardiography (ECO) procedure before the procedure and kaleidoscope during the procedure…
- Conditions
- Anxiety, Child, Only, Echocardiography
- Trial name
- NCT04334733
- Testing
- Cartoon group, Kaleidoscope group, Cartoon+Kaleidoscope group
- Where
- Turkey (Türkiye)
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Yaws, Treponema Infection
Single-dose Azithromycin for the Treatment of Yaws
Yaws, an endemic treponematosis and as such a neglected tropical disease (NTD), is currently making a comeback in children in rural areas. Injectable long acting penicillin remains the drug of choice for the treatment of yaws.
- Conditions
- Yaws, Treponema Infection, Neglected Tropical Disease
- Trial name
- NCT01382004
- Testing
- Penicillin-G-benzathine, Azithromycin
- Where
- Papua New Guinea
- Volunteers
- 255 people
- Sponsor
- Lihir Medical Centre
Problem Behavior, Developmental Delay
Problem Behavior Assessment and Intervention in IDEA Part C Services
The purpose of this study is to evaluate the effect of function-based assessment and intervention to reduce problem behavior in children with developmental disability or delay in the context of IDEA Part C services.
- Conditions
- Problem Behavior, Developmental Delay, Developmental Disability
- Trial name
- NCT06771284
- Testing
- Function-based assessment and intervention
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Cerebral Palsy, Spastic Dysarthria
Application of Vibration Wave Therapy to the Children Suffering From Cerebral Palsy and Tongue Spastic Dysarthria
Vibration therapy is the widely used in many neurological disorders for different type of problems. Recently, it is being used by researchers for the betterment of motor disorders and muscle movements of the cerebral palsy…
- Trial name
- NCT04222049
- Testing
- Vibro Tactile Gadget
- Where
- Pakistan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- National University of Science and Technology, Pakistan
Allergic Rhinitis
Study to Evaluate Diphenhydramine in Children and Adolescents
To characterize the pharmacokinetics of diphenhydramine in two pediatric populations: children, ages 2 to < 12 years, and adolescents, ages 12 to < 18 years.
- Trial name
- NCT00762749
- Testing
- diphenhydramine HCl
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Acute Appendicitis, Children, Only
Plasma Sodium: a Predictor of Perforation in Acute Appendicitis. (The NAP-study)
This clinical prospective diagnostic accuracy study assesses plasma sodium concentration using blood gas analysis at the emergency department in children, age 1-15 years, with suspected acute appendicitis.
- Trial name
- NCT04806789
- Where
- Sweden
- Volunteers
- 451 people
- Sponsor
- Urban Fläring
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