Clinical trials: Onychomycosis
Infected Toenails, Onychomycosis
PinPointe FootLaser for the Treatment of Onychomycosis
To evaluate the safety and efficacy of the PathoLase FootLaser treatment of infected toenails.
- Trial name
- NCT00935649
- Testing
- PinPointe FootLaser
- Where
- 4 sites in United States, Canada
- Volunteers
- 134 people
- Sponsor
- PathoLase, Inc.
Onychomycosis of Toenails
Evaluation of the Performance of a Fungal Nail Treatment on the Visual Signs of Onychomycosis
This is a prospective, open label, non-comparative clinical investigation to evaluate the performance of a Fungal Nail Treatment on the visual signs of onychomycosis.
- Trial name
- NCT02546258
- Testing
- A Fungal Nail Treatment
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Onychomycosis
A Retrospective Analysis of the Effects of Low Level Laser Therapy on Toenail Onychomycosis
The purpose of this study is to determine whether low level laser therapy (LLLT) using the Erchonia LUNULA device is effective in increasing clear nail in toenails with onychomycosis.
- Trial name
- NCT02588599
- Testing
- Erchonia LUNULA
- Volunteers
- 54 people
- Sponsor
- Erchonia Corporation
Distal Subungual Onychomycosis
Study to Evaluate the Efficacy and Safety of Topical MOB015B in the Treatment of Mild to Moderate Distal Subungual Onychomycosis (DSO)
The primary objective of this study is to evaluate the efficacy of topical MOB015B in patients with mild to moderate distal subungual onychomycosis (DSO).
- Trial name
- NCT02866032
- Testing
- MOB015B, Ciclopirox 80 mg/g
- Where
- 3 sites in Germany, Poland and 1 more
- Volunteers
- 452 people
- Sponsor
- Moberg Pharma AB
Onychomycosis
Efficacy and Safety of RV4104A Ointment in Onychomycosis
The purpose of the study is to evaluate the efficacy of RV4104A ointment versus bifonazole-urea ointment for the complete removal of the clinically infected nail plate area in patients with toenail onychomycosis.
- Trial name
- NCT00808366
- Testing
- Keratolytic/Antifungal
- Where
- France
- Volunteers
- 228 people
- Sponsor
- Pierre Fabre Dermo Cosmetique
Onychomycosis
Efficacy and Safety Study of ME1111 in Patients With Onychomycosis
The purpose of the study is to determine the safety and efficacy of high and low strength of ME1111 solutions compared to the vehicle in the treatment of onychomycosis of the toenail.
- Trial name
- NCT02022215
- Testing
- ME1111 Solution, Low strength, ME1111 Solution, High strength, Matching Vehicle Solution
- Where
- 31 sites in United States
- Volunteers
- 304 people
- Sponsor
- Meiji Seika Pharma Co., Ltd.
Onychomycosis of Toenails
Efficacy and Safety Evaluation of AN2690 Topical Solution to Treat Onychomycosis of the Toenail
The purpose of this study is to determine whether AN2690 topical solution is a safe and effective treatment for onychomycosis of the toenail.
- Trial name
- NCT01270971
- Testing
- AN2690 Topical Solution, 5%, Solution Vehicle
- Where
- 27 sites in United States
- Volunteers
- 594 people
- Sponsor
- Pfizer
Mild to Moderate Onychomycosis Due to Dermatophyte
Phase IV Clinical Trial to Evaluate the Efficacy and Safety of Jublia® in Mild to Moderate Toenail Onychomycosis
The antifungal efficacy and safety of Jublia® topical solution will be assessed through an administration for 48 weeks to patients diagnosed with a mild or moderate onychomycosis due to dermatophyte.
- Trial name
- NCT03280927
- Testing
- Jublia®
- Where
- South Korea
- Volunteers
- 97 people
- Sponsor
- Dong-A ST Co., Ltd.
Onychomycosis
A Study to Compare the Blood Levels of Albaconazole in Healthy Subjects Who Have Received a Single Dose of 400 mg Albaconazole as a Tablet Versus Albaconazole as a Capsule
The purpose of this study is to determine whether albaconazole tablets and albaconazole capsules (single 400mg dose) act in the body in the same way over a period of time.
- Trial name
- NCT01039883
- Testing
- Albaconazole tablet 400mg, Albaconazole 100mg capsules, then albaconazole 400mg tablet
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Stiefel, a GSK Company
Onychomycosis
Efficacy and Safety Study of Iontophoretic Application of Terbinafine Gel in Subjects With Onychomycosis
The purpose of this study is to determine if the iontophoretic application of terbinafine gel is safe and effective for teh treatment of distal subungual onychomycosis
- Trial name
- NCT01080079
- Testing
- Terbinafine Hydrochloride, Purified Water
- Where
- 9 sites in United States, Canada
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Nitric BioTherapeutics, Inc
Onychomycosis of Toenail
A Phase 2 Study to Assess the Effectiveness of Topical Terbinafine in Participants With Mild to Moderate Onychomycosis of the Toenails
Onychomycosis is a fungal infection of the toenail caused by a range of organisms, including dermophytes, non-dermophyte molds, and yeasts.
- Trial name
- NCT07382427
- Testing
- 2.4% Topical Terbinafine, 10% Topical Efinaconazole, Vehicle Control
- Volunteers
- 200 people
- Sponsor
- Onyx Axiom
Onychomycosis
Randomized, Placebo-Controlled, Double-Blind, Parallel-Group, Multi-Site Phase 2b Clinical Study
A Randomized, Placebo-Controlled, Double-Blind, Parallel-Group, Multi- Site Phase 2b Clinical Study to Assess the Efficacy, Safety and Tolerability of 8-Week Regimens of NVXT topical product in Patients with Mild to Moderate…
- Trial name
- NCT02933879
- Testing
- NVXT topical
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Onychomycosis
Evaluation of a Combination of Two Medical Devices and One Device Use in the Treatment of Toenail Onychomycosis
The goal of this clinical investigation is to evaluate the efficacy of the tested products in medium to moderate onychomycosis after 112 days of treatments.
- Trial name
- NCT06175013
- Testing
- Sérum PURIFIANT, Sérum PURIFIANT in association Sérum BOOSTER
- Where
- Mauritius
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Swiss Footcare Laboratories - Poderm Professional
Onychomycosis
Open-Label Pharmacokinetics (PK)/Safety Study of Luliconazole Solution, 10% in Distal Subungual Onychomycosis
To determine the safety, tolerability, systemic exposure and pharmacokinetics of luliconazole after repeat daily topical application of Luliconazole Solution, 10% in a maximal use setting in adults with distal subungual…
- Trial name
- NCT01044381
- Testing
- Luliconazole Solution, 10%
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Topica Pharmaceuticals
Onychomycosis of Toenail
Clinical Trial of Topical ABL01 Treatment of Onychomycosis
This clinical trial seeks to investigate if an experimental medical device, ABL01, can be used to treat onychomycosis. In a 1-year trial the effectiveness of ABL01 will be tested against placebo in 70 study subjects with…
- Trial name
- NCT03141840
- Testing
- ABL01
- Where
- Sweden
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Abbell AB
Onychomycosis
TDT 067 Onychomycosis Study
The aim of this study is to establish the efficacy, clinical benefits, and safety of treatment with TDT 067 for clinically diagnosed distal subungual onychomycosis of the toenails caused by dermatophytes confirmed by positive…
- Trial name
- NCT01145807
- Testing
- TDT067, Transfersome
- Where
- United States
- Volunteers
- 738 people
- Sponsor
- Celtic Pharma Development Services
Foot Dermatoses
Treatment of Onychomycosis With Loceryl (Amorolfine) Nail Lacquer 5% Versus Ciclopirox Nail Lacquer
The main objective of this study is to compare subject's compliance and satisfaction for two modes of treatment of toenails infection (Onychomycosis) with Loceryl Nail Lacquer (Loceryl NL) and Ciclopirox Nail Lacquer (Ciclopirox…
- Trial name
- LOOP (NCT02679911)
- Testing
- Loceryl NL, Ciclopirox NL
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Galderma R&D
Foot Dermatoses
Treatment of Onychomycosis With Loceryl (Amorolfine) Nail Lacquer 5% Versus a Two-course Treatment With Urea 40% Ointment and Bifonazole Cream 1%
The main objective of this study is to compare subject adherence and satisfaction for two modes of treatment toenails infection (Onychomycosis) with Loceryl Nail Lacquer (Loceryl NL) and a Fungal Nail Treatment Set containing…
- Trial name
- OPEN (NCT02705664)
- Testing
- Loceryl Nail Lacquer, Urea Ointment, Bifonazole Cream
- Where
- Iceland
- Volunteers
- 22 people
- Sponsor
- Galderma R&D
Onychomycosis/Onycholysis and Tinea Pedis
Safety and Pharmacokinetics of Terbinafine Hydrogen Chloride (HCl) Nail Lacquer in Patients With Onychomycosis
In this study, the safety and pharmacokinetics of 10 % terbinafine hydrogen chloride (HCl) nail lacquer wre investigated by comparison with vehicle control and 1% terbinafine cream
- Trial name
- NCT00691184
- Testing
- Terbinafine Hydrochloride, Terbinafine
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- NexMed (U.S.A.), Inc. (subsidiary of Apricus Biosciences, Inc.)
Onychomycosis of Toenail, Onychomycosis
Early Feasibility Study to Evaluate the Efficacy of the RenewalNail™ Plasma Treatment System in Patients With Onychomycosis (Fungal Nail)
A study to determine if a three-treatment protocol with the RenewalNail™ plasma treatment system over a week will result in mycological cure and/or clear nail growth on the treated hallux toe.
- Trial name
- NCT03216200
- Testing
- plasma treatment
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- DeviceFarm, Inc.