Clinical trials: Onychomycosis of Toenails
Onychomycosis of Toenails
Evaluation Study for the Efficacy and Safety of PinPointe FootLaser in Treatment for Onychomycosis
The purpose of this study is to assess the clinical efficacy and safety of the PinPointe Foot Laser device for the treatment of patients with onychomycosis who have been previously treated with oral Terbinafine and failed.
- Trial name
- NCT01920178
- Testing
- PinPointe Foot Laser
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Cambridge Health Alliance
Distal Subungual Onychomycosis
A Study to Evaluate TMI-358 in the Treatment of Distal Subungual Onychomycosis
The purpose of this study is to determine if a local treatment is effective for the treatment of toenail fungus (distal subungual onychomycosis).
- Trial name
- NCT01093118
- Testing
- TMI-358, MMI-467
- Where
- 7 sites in United States
- Volunteers
- 120 people
- Sponsor
- Talima Therapeutics, Inc.
Onychomycosis of Toenails
Evaluation of the Performance of a Fungal Nail Treatment on the Visual Signs of Onychomycosis
This is a prospective, open label, non-comparative clinical investigation to evaluate the performance of a Fungal Nail Treatment on the visual signs of onychomycosis.
- Trial name
- NCT02546258
- Testing
- A Fungal Nail Treatment
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Onychomycosis
Efficacy, Safety, and Tolerability of HTS-519 Insert in Patients With Toenail Fungus of the Big Toenail
The purpose of this study is to assess the efficacy, safety and tolerability of HTS-519 Inserts in the treatment of mild to moderate toenail fungus disease of the big toenail.
- Trial name
- NCT02798380
- Testing
- HTS-519 Insert
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hallux, Inc.
Onychomycosis
Study Comparing SUBA™-Itraconazole With SPORANOX® (Itraconazole) in the Treatment of Onychomycosis
The objective of this study is to compare the relative efficacy and safety of SUBA™-Itraconazole Capsules (HalcyGen Ltd) to an already marketed oral formulation of itraconazole SPORANOX® (itraconazole) capsules (Janssen Pharma)…
- Trial name
- NCT00791219
- Testing
- SUBA-itraconazole, Itraconazole
- Where
- 8 sites in United States
- Volunteers
- 175 people
- Sponsor
- Halcygen Pharmaceuticals Limited
Onychomycosis
Safety and Efficacy of NAB001 in the Treatment of Mild to Moderate Onychomycosis of the Toenails
The objectives of this study are to assess the safety of NAB001 for topical treatment of mild to moderate distal onychomycosis of the toenails over 52 weeks and to compare the efficacy of NAB001 to vehicle alone at the end of the…
- Trial name
- NCT01208129
- Testing
- NAB001
- Where
- 25 sites in United States
- Volunteers
- 458 people
- Sponsor
- Promius Pharma, LLC
Onychomycosis of Toenail
Safety and Efficacy of Next Science Gel on Toenail Fungus
This is a 52 week, 20-patient open-label pilot study on the safety and efficacy of Next Science Wound gel in the treatment of mild to moderate Distal Subungual Onychomycosis.
- Trial name
- NCT04042857
- Testing
- Next Science Treatment Gel
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Next Science TM
Onychomycosis
Diode Laser Treatment of Onychomycosis
The purpose of this study is to evaluate the V-Raser diode laser system with investigational Nail Fungus Handpiece in the treatment of onychomycosis.
- Trial name
- NCT01452490
- Testing
- Diode Laser Treatment
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- ConBio, a Cynosure Company
Distal and Lateral Subungual Onychomycosis
Safety and Efficacy of Luliconazole Solution, 10% in Subjects With Mild to Moderate Onychomycosis
The purpose of this study is to determine the safety and efficacy of a topical antifungal formulation, Luliconazole Solution, 10%, in the treatment of adults with onychomycosis of the toenails.
- Trial name
- SOLUTION (NCT01431820)
- Testing
- Luliconazole Solution, 10%, Vehicle Solution
- Where
- 28 sites in United States
- Volunteers
- 334 people
- Sponsor
- Topica Pharmaceuticals
Onychomycosis
Pharmacokinetics and Safety Study of ME1111 in Moderate to Severe Onychomycosis Patients
This study is Randomized, Double-Blind, Vehicle-Controlled, Multiple-Dose Study. The purpose is to determine the safety, tolerability, systemic exposure and pharmacokinetics of ME1111 after repeated daily topical application of…
- Trial name
- NCT01841996
- Testing
- ME1111 solution, Vehicle Solution
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Meiji Seika Pharma Co., Ltd.
Onychomycosis of Toenails
Efficacy and Safety Evaluation of AN2690 Topical Solution to Treat Onychomycosis of the Toenail
The purpose of this study is to determine whether AN2690 topical solution is a safe and effective treatment for onychomycosis of the toenail.
- Trial name
- NCT01270971
- Testing
- AN2690 Topical Solution, 5%, Solution Vehicle
- Where
- 27 sites in United States
- Volunteers
- 594 people
- Sponsor
- Pfizer
Onychomycosis of Toenail
Laser Treatment of Toenail Onychomycosis With a 1064 nm Nd:YAG-laser
This study aims to assess if laser treatment can cure fungal infection in toenails. Nail clippings from eligible subjects were obtained and randomised into two groups.
- Trial name
- NCT05260450
- Testing
- 1064 nm Nd:YAG-laser therapy
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Aalborg University Hospital
Mild to Moderate Onychomycosis Due to Dermatophyte
Phase IV Clinical Trial to Evaluate the Efficacy and Safety of Jublia® in Mild to Moderate Toenail Onychomycosis
The antifungal efficacy and safety of Jublia® topical solution will be assessed through an administration for 48 weeks to patients diagnosed with a mild or moderate onychomycosis due to dermatophyte.
- Trial name
- NCT03280927
- Testing
- Jublia®
- Where
- South Korea
- Volunteers
- 97 people
- Sponsor
- Dong-A ST Co., Ltd.
Onychomycosis
Safety and Efficacy Study of Subjects With Onychomycosis of the Great Toenail
The purpose of the study is to determine the safety and efficacy of 5.0% and 7.5% AN2690 Solution in the treatment of distal, subungual onychomycosis of the great target toenail.
- Trial name
- NCT00679523
- Testing
- AN2690 Solution, 5.0%, AN2690 Solution, 7.5%
- Where
- 9 sites in Mexico
- Volunteers
- 60 people
- Sponsor
- Pfizer
Onychomycosis
Absorption and Systemic Study of AN2690 in Patients With Moderate to Severe Onychomycosis (ADME I)
The purpose of the study is to determine the absorption, systemic pharmacokinetics and accumulation in the nail of AN2690 during a 28 day period of daily application of a 7.5% solution of AN2690 to all 10 toenails of up to 25…
- Trial name
- NCT00680160
- Testing
- AN2690
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Pfizer
Onychomycosis
A Study of the Systemic Absorption of MOB015B
A Study of the Systemic Absorption of Once Daily MOB015B when Applied for 28 Days in Subjects with Moderate to Severe Onychomycosis of the Toenails.
- Trial name
- NCT03244280
- Testing
- MOB015B
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Moberg Pharma AB
Dermatologic Disease, Onychomycosis of Toenail
Photodynamic Therapy and Topical Antifungal for Onychomycosis in Patients With Diabetes.
There are different therapeutic alternatives for onychomycosis. Systemic therapy is widely used due to its easy accessibility, low cost and high efficacy, but may be associated with systemic adverse events and drug-drug…
- Conditions
- Dermatologic Disease, Onychomycosis of Toenail, Diabetic Foot, Diabetes Mellitus
- Trial name
- NCT06485050
- Testing
- Photodynamic therapy
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Universidad Complutense de Madrid
Onychomycosis
Study of the Use of Low Level Laser Light Therapy to Treat Toenail Fungus
The purpose of this study is to determine whether low level laser light is effective in the treatment of toenail fungus.
- Trial name
- NCT01534689
- Testing
- Erchonia FX-405™ Laser
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Erchonia Corporation
Onychomycosis of Toenail
Photodynamic Therapy For Onychomycosis
The purpose of this study is clinical and mycological clearance of onychomycosis using photodynamic therapy (PDT) with aminolevulinic acid (ALA) 10% gel at 6 months, 3 months, 9 months and 12 months
- Trial name
- NCT07756671
- Testing
- ALA 10% gel, PDT, Urea
- Where
- 3 sites in United States
- Volunteers
- 5 people
- Sponsor
- The University of Texas Health Science Center, Houston
Infected Toenails, Onychomycosis
PinPointe FootLaser for the Treatment of Onychomycosis
To evaluate the safety and efficacy of the PathoLase FootLaser treatment of infected toenails.
- Trial name
- NCT00935649
- Testing
- PinPointe FootLaser
- Where
- 4 sites in United States, Canada
- Volunteers
- 134 people
- Sponsor
- PathoLase, Inc.