Clinical trials: Oocyte
Infertility, Female
Double Trigger in Patients With Low Number of Oocytes Retrieved Per Number of Preovulatory Follicles
The aim of this randomized controlled trial is to determine whether co-administration of GnRH agonist and hCG for final oocyte maturation ( 40 and 34 h prior to oocyte retrieval , respectively) can increase the oocytes yield in…
- Trial name
- NCT04407065
- Testing
- Double trigger, HCG trigger
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Riyadh Fertility and Reproductive Health center
Oocyte Cryopreservation
Oocyte Cryopreservation Registry (HOPE Registry)
Phase IV, prospective multicenter, observational Registry will track cycle outcomes for subjects who are thawing frozen oocytes for subsequent use through in vitro fertilization (IVF) and embryo transfer (ET)
- Trial name
- NCT00699400
- Where
- 15 sites in United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- EMD Serono
Infertility, Female
CAPA In-vitro Oocyte Maturation
In vitro oocyte maturation (IVM) is a mild-approach assisted reproductive technology (ART). Because of its simplicity, the more favorable financial implications (reduced cost) for patients, and the lower health risk profile of…
- Trial name
- NCT06984081
- Testing
- CAPA IVM
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Breast Cancer
Risk of Infertility Related to Adjuvant Chemotherapy for Early Breast Cancer: Oocyte/Embryo Cryopreservation
The aim of the study is to perform a French multicenter prospective interventional study in order to assess the feasibility and safety of ovarian hyperstimulation for oocyte / embryo cryopreservation in young women with breast…
- Trial name
- CHACRY (NCT02871167)
- Testing
- Controlled ovarian hyperstimulation (COH), Oocyte/embryo freezing
- Where
- 28 sites in France
- Volunteers
- 140 people
- Sponsor
- Centre Oscar Lambret
Infertility, Assisted Reproductive Technology
Prognostic Value of Progesterone on Oocyte Retrieval Day for In Vitro Fertilization Outcome
This observational study aims the potential role of serum progesterone levels on the day of oocyte pick-up on the probability of pregnancy, in patients undergoing antagonist IVF cycles.
- Trial name
- NCT02109900
- Testing
- Serum Progesterone Levels
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Invitro Fertilizaion
Prediction of Metaphase II Oocytes According to Different Levels of Serum AMH in Poor Responders Using the Antagonist Protocol
A multicentric study looked into 179 poor responders who underwent antagonist protocol in ICSI cycles Gonadotrophines is started on day 2 with HMG until the day of HCG administration with starting dose 300IU to 450IU,with no…
- Trial name
- NCT03484611
- Testing
- GnRH antagonist, Gonadotropins, Human chorionic gonadotropin
- Where
- Egypt
- Volunteers
- 179 people
- Sponsor
- Cairo University
Breast Cancer
Oocyte Recovery During Tamoxifen Adjuvant Therapy
Survival in young patients with cancer has increased and also have increased the adverse long-term side effects of chemotherapy, there is a large number of women who experience loss of ovarian function without accomplishing their…
- Trial name
- TAMOXIFERT (NCT02355600)
- Testing
- Oocyte retrieval
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Infertility/Sterility
Markers in Follicular Fluid and in Embryo Culture Medium as a Marker of Oocyte and Embryo Quality
Assessment of the quality of follicular fluid and early embryo via chemical markers.
- Trial name
- NCT03350009
- Where
- Israel
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Fertility Preservation
Follicular Flushing Versus Direct Aspiration in Transabdominal Oocyte Retrieval
The goal of this observational study is to learn whether rinsing the egg sacs (follicles) during egg collection helps doctors collect more eggs in women with low egg reserve.
- Trial name
- NCT07877025
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Centrum Clinic IVF Center
Complications; Artificial Fertilization, Introduction of Embryo in Embryo Transfer
Growth Hormone (GH) in in Vitro Fertilization (IVF) Poor-responder Patients
Experimental study to evaluate if rGH addition to a standard controlled ovarian stimulation treatment improves ovarian response in women with previous poor ovarian response.
- Trial name
- FUNDEX001 (NCT01298960)
- Testing
- Somatropin
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Fundacion Dexeus
Abnormal Fertilization, Infertility
Outcomes of Embryos Created From Abnormally Fertilized Oocytes
The purpose of this study is to retrospectively analyze data from multiple clinics in a fertility network on embryos that were created from abnormally fertilized oocytes (AFO) including the rate of transfers and any clinical…
- Trial name
- NCT07666243
- Volunteers
- 92 people
- Sponsor
- Inception Fertility Research Institute, LLC
Ovarian Stimulation, Reproductive Techniques, Assisted
The Effect of Dual Trigger for Final Oocyte Maturation on IVF/ICSI Outcomes in Patients With Suboptimal Ovarian Response
Recently, in patients with a suboptimal ovarian response, a study of the role of adding a single dose of GnRH agonist to a standard dose of hCG to initiate final oocyte maturation has also been studied. Griffin et al.
- Trial name
- NCT04549649
- Testing
- Dual triggering
- Where
- Iran
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Low Ovarian Reserve, Poor Quality Oocytes
Improving the Reproductive Outcome of Poor Quality Ova by Injection of Autologous Somatic Mitochondria
A prospective randomized controlled trial (RCT) to determine the effect of injecting an autologous somatic mitochondria concentrate, together with the spermatozoon during ICSI, into oocytes of older and or poor prognosis in vitro…
- Trial name
- NCT01631578
- Testing
- Injection of an autologous mitochondria to the oocyte.
- Where
- Israel
- Sponsor
- Hadassah Medical Organization
Infertility
Diafert for Embryo Selection and Fertility Improvement (DESTINy)
Prospective, single-center, single-blind, randomized, controlled, two-arm, interventional study.
- Trial name
- DESTINy (NCT02593513)
- Testing
- Daifert, Control Group
- Where
- Hungary
- Volunteers
- 108 people
- Sponsor
- Forest Laboratories
Infertility, Female
CAPA-IVM Versus STANDARD IVM
The aim of this study is to evaluate the effectiveness and safety of CAPA-IVM versus standard IVM in women with polycystic ovarian morphology (PCOM) or polycystic ovary syndrome (PCOS) .
- Trial name
- NCT03921710
- Testing
- CAPA-IVM, Standard-IVM
- Where
- Vietnam
- Volunteers
- 80 people
- Sponsor
- Mỹ Đức Hospital
Infertility, Female, Pain, Postoperative
Assessing Efficacy of Intravenous Acetaminophen for Perioperative Pain Control for Oocyte Retrieval
In this research study we want to learn more about how effective certain medications are at reducing pain after oocyte (egg) retrieval surgery and how effective they are at reducing the time between the retrieval and discharge…
- Trial name
- NCT03073980
- Testing
- IV Acetaminophen, PO Acetaminophen
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Embryo Implantation
Assessment of Endometrial Receptivity in Recipients of Donated Oocytes
The purpose of this study is to determine whether endometrial receptivity markers obtained by endometrial sampling are effective in prediction of in vivo human embryo implantation.
- Trial name
- ERPOD (NCT00506480)
- Testing
- endometrial sampling
- Volunteers
- 100 people
- Sponsor
- Hadassah Medical Organization
Infertility
A Comparative Study of Sibling Oocytes: ICSI vs. the PICSI Sperm Selection Method
The aim of this research is to compare sibling oocytes using two sperm selection methods for choosing the best quality spermatozoa before they are injected into oocytes and the influence of each of these methods on embryo quality…
- Trial name
- NCT03240302
- Testing
- ICSI petri dish, PICSI petri dish
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Hillel Yaffe Medical Center
Ovarian Stimulation
Impact of Three Different Gonadotrophin Regimes on Egg Donation Program
Exploratory study assessing the effect of three gonadotrophin protocols on Controlled Ovarian Stimulation (COS) parameters and IVF outcome in oocyte donors undergoing GnRH analogue (long protocol).
- Trial name
- NCT00829075
- Testing
- r-FSH, HP-hMG, r-FSH plus HP-hMG
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Infertility
Hormone-free Antral Retrieval for Viable Embryo Storage & Transfer
This study is testing whether eggs can be collected from small follicles without using the usual ovarian stimulation medications. Participants will have up to three egg retrieval procedures.
- Trial name
- HARVEST (NCT07801105)
- Testing
- CAPA-IVM System, Serial Unstimulated Transvaginal Oocyte Retrieval, ICSI, Blastocyst Culture, PGT-A, Embryo Vitrification/Accumulation, and Single Euploid Embryo Transfer
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Kevin Doody