Clinical trials: Oocyte
Infertility
Automation of Oocyte and Embryo Vitrification
Purpose: This study aims to test whether a new automated system can freeze human eggs and embryos as effectively as the current manual method performed by laboratory staff.
- Trial name
- NCT07197983
- Testing
- Automated Vitrification, Manual Vitrification
- Where
- United Kingdom
- Volunteers
- 125 people
- Sponsor
- Conceivable Life Sciences
Infertility, Male Factor Infertility
A Randomized Clinical Trial Comparing Embryo Euploidy Rates Following Ultrashort Versus Standard Abstinence
This research is being done to determine if producing sperm after an ultrashort period of abstinence (1 hour of abstinence) will be effective in improving the rates of embryos with normal chromosomes (structures that carry…
- Trial name
- NCT07062237
- Testing
- Ultrashort abstinence, Standard abstinence
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- UConn Health
Infertility
Influence of Ethnical Differences on the Egg Cell Collected in Patients Undergoing Fertility Treatment
Investigators wants to analyze the differences considering the country of origin, ethnicity, characteristics, reproductive history and habits of participants undergoing in vitro fertilization (IVF) / intracytoplasmic sperm…
- Trial name
- NCT03927417
- Where
- United Arab Emirates
- Volunteers
- 1,117 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Infertility, Oocyte Recipient
Single Embryo Transfer vs. Double Embryo Transfer in an Oocyte Donation Programme
Experimental study to assess the efficacy of single embryo transfer (SET) with respect to double embryo transfer (DET) in an oocyte donation programme, 160 recipients will be randomized in two groups
- Conditions
- Infertility, Oocyte Recipient, Single Embryo Transfer/Double Embryo Transfer, Cumulative Pregnancy Rate
- Trial name
- NCT01228474
- Testing
- Select the Number of embryos to transfer
- Where
- Spain
- Volunteers
- 65 people
- Sponsor
- Fundacion Dexeus
IVF Treatment
Follicle Size and Oocyte Development
Studies have shown that the follicles greater in diameter was most likely to have a mature oocyte that was capable of fertilization and best suited for development into a high-quality embryo.
- Trial name
- AMJH (NCT03660813)
- Testing
- Follicle measurment, Ovitrelle ( Hcg 250 mcg), Decapeptyl ( GnRH Agonist 0.1 mg*2 )
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Fertilization
Artificial Assisted Activation Following in Fertilization Failure
Fertilization failure is a common problem in assisted reproductive Technology (ART). The main reason for fertilization failure of conventional IVF fertilization is sperm penetration failure, and the main reason of ICSI is…
- Trial name
- NCT04523103
- Testing
- Artificial Assisted Activation
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
INFERTILITY, Fertility Preservation
Evolutive Potential of Embryos Obtained From Oocytes After Luteal Phase Ovarian Stimulation
The purpose of this study is to evaluate the clinical pregnancy rate per embryo transfer in oocytes recipients obtained after ovarian stimulation during the luteal phase of oocytes donors .
- Conditions
- INFERTILITY, Fertility Preservation, Ovulation Induction, Vitrification
- Trial name
- NCT01645241
- Testing
- gonadotropins plus GnRH antagonists, ganirelix
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Fundacion Dexeus
Androgen Profile, Inflammatory Markers
Effect of Resveratrol on Metabolic Parameters and Oocyte Quality in PCOS Patients
Polycystic ovary syndrome (PCOS) is characterized by enlarged ovaries, menstrual irregularity and hyperandrogenism and is the most common cause of oligoovulatory infertility.
- Conditions
- Androgen Profile, Inflammatory Markers, IVF Outcome
- Trial name
- RES-IVF (NCT01782911)
- Testing
- Resveratrol
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
Fertility Preservation
Oocyte Cryopreservation
The specific aim of this study is to further develop methods of oocyte cryopreservation and evaluate their impact on reproductive outcomes.
- Trial name
- NCT01696786
- Testing
- Oocyte cryopreservation
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Male Infertility, Azoospermia
Evaluating the Safety and Clinical Efficacy of the BAIBYS™ System in Intracytoplasmic Sperm Injection (ICSI)
This study looks at an investigational automated, artificial intelligence (AI)-based sperm selection technology called the BAIBYS™ System.
- Trial name
- Benchmark (NCT06990906)
- Testing
- BAIBYS Sperm selection, Intra cytoplasmatic sperm injection, Conventional manual sperm selection
- Where
- 3 sites in United States, Israel and 1 more
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- BAIBYS Fertility
OHSS (Ovarian Hyperstimulation)
Triggering of Final Oocyte Maturation With GnRHa (Buserelin) in GnRH Antagonist Cycles
The purpose of this study is to possibly further improve the clinical outcome and explore the incidence of OHSS in patients, who have final oocyte maturation with GnRHa (Buserelin) in GnRH antagonist IVF/ICSI cycles
- Trial name
- NCT00627406
- Testing
- Buserelin and Pregnyl, Pregnyl
- Where
- Denmark
- Volunteers
- 384 people
- Sponsor
- Regionshospitalet Viborg, Skive
Infertility, Infertility, Female
Assessing Ketorolac (Toradol) at Oocyte Retrieval
To determine if a nonsteroidal anti-inflammatory drug (NSAID), Ketorolac (Toradol), can improve pain control and decrease narcotic use after undergoing egg retrieval.
- Conditions
- Infertility, Infertility, Female, Oocyte Retrieval, Postoperative Pain
- Trial name
- Alleviate (NCT06026553)
- Testing
- Ketorolac (Toradol)
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- Shady Grove Fertility Reproductive Science Center
Ovulation, Ovarian Function
Exogenous Progesterone as Ovulation Trigger
The goal of this clinical trial is to learn whether the sudden administration of vaginal micronized progesterone during the late follicular phase can trigger an LH surge and reactivation of oocyte meiosis in healthy oocyte donors…
- Conditions
- Ovulation, Ovarian Function, Assisted Reproductive Treatments, Oocyte Maturation
- Trial name
- PRO-TRIGGER (NCT07466199)
- Testing
- Vaginal micronized progesterone
- Where
- Portugal
- Volunteers
- 10 people
- Sponsor
- Instituto Valenciano de Infertilidade de Lisboa
In Vitro Fertilisation (IVF) Treatment
Effect of Oxytocin and Vasopressin Antagonists on Uterine Contractions
The main purpose of this clinical research trial was to evaluate the effects of barusiban and atosiban compared to placebo on luteal phase uterine contractions in oocyte donors supplemented with progesterone.
- Trial name
- OVANCON (NCT00587327)
- Testing
- Barusiban, Atosiban
- Where
- 5 sites in Belgium, Czechia and 1 more
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Infertility
Subcutaneous Progesterone Versus Vaginal Progesterone for Endometrial Preparation in Fresh Donated Oocytes Recipients
Randomised, prospective, investigator-blinded, controlled, single-centre study to assess the impact on the ongoing pregnancy rate with the use of two progesterones with different administration routes, in recipients of fresh…
- Trial name
- NCT02363127
- Testing
- subcutaneous progesterone, vaginal progesterone
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Instituto Bernabeu
Fertility
Effect of Timing of Oocyte Denudation Before ICSI in an Oocyte Donation Model
Analyze the effect of preincubation time of oocyte on the results of ICSI in a oocyte donation model.
- Trial name
- NCT03121924
- Testing
- timing for oocyte denudation and Intracytoplasmatic Sperm injection
- Where
- Argentina
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Hospital Italiano de Buenos Aires
Infertility, Female
Can Virtual Reality Technology Improve the Patient Experience in Oocyte Retrieval?
A non-pharmacological, non-blinded, randomized cohort study that will investigate the effect of Virtual Reality technology on the patient experience during oocyte retrieval.
- Trial name
- NCT05826938
- Testing
- Virtual reality technology
- Where
- Denmark
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Peter Humaidan
IVF, Procedural Pain
Virtual Reality for Anxiety and Pain Management During Oocyte Retrieval in IVF/ICSI Treatment
Despite current anxiety and pain management during oocyte retrieval in IVF/ICSI treatment by conscious sedation, oocyte retrieval often remains painful and stressful for patients.
- Conditions
- IVF, Procedural Pain, Procedural Anxiety
- Trial name
- VitRo (NCT05555498)
- Testing
- Virtual Reality glasses
- Where
- Netherlands
- Volunteers
- 112 people
- Sponsor
- Amsterdam UMC, location VUmc
Oocyte Donation, Infertility, Female
Transfer Strategy in an Oocyte Donation Programme
It has been previously shown that although the activation of the embryonic genome can begin as early as two days of initiation of the embryonic development (D2), it is expressed on day 3 (D3).
- Conditions
- Oocyte Donation, Infertility, Female, Embryo Transfer
- Trial name
- NCT03088735
- Testing
- Blastocyst-stage embryo transfer strategy, Cleavage-stage embryo transfer strategy
- Where
- Spain
- Volunteers
- 134 people
- Sponsor
- Fundacion Dexeus
In Vitro Fertilization, Infertility
Sibling Oocyte Study of Medium for In Vitro Fertilization/Intracytoplasmic Sperm Injection (IVF/ICSI) With no Human Serum Albumine
The purpose of this study is to determine if a new medium with no human serum albumine added is as good as the media conventionally used for IVF/ICSI.
- Trial name
- NCT00541892
- Testing
- Medium with no human serum albumine added, Conventional medium
- Where
- Norway
- Sponsor
- Sykehuset Telemark